loxoprofen has been researched along with Cancer of Stomach in 1 studies
loxoprofen: RN given refers to parent cpd without isomeric designation; structure in first source
loxoprofen : A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-[(2-oxocyclopentyl)methyl]phenyl group. A prodrug that is rapidly converted into its active trans-alcohol metabolite following oral administration.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We recently showed that NSAIDs such as indomethacin and celecoxib have direct cytotoxicity (ability to induce necrosis and apoptosis in gastric mucosal cells) due to their membrane permeabilizing activities, which is involved in NSAID-induced gastric lesions." | 3.76 | Low direct cytotoxicity of loxoprofen on gastric mucosal cells. ( Arai, Y; Ishihara, T; Kimoto, A; Mizushima, T; Okamoto, Y; Otsuka, M; Suemasu, S; Tanaka, K; Yamakawa, N; Yokomizo, K, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yamakawa, N | 1 |
| Suemasu, S | 1 |
| Kimoto, A | 1 |
| Arai, Y | 1 |
| Ishihara, T | 1 |
| Yokomizo, K | 1 |
| Okamoto, Y | 1 |
| Otsuka, M | 1 |
| Tanaka, K | 1 |
| Mizushima, T | 1 |
1 other study available for loxoprofen and Cancer of Stomach
| Article | Year |
|---|---|
Low direct cytotoxicity of loxoprofen on gastric mucosal cells.
Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; | 2010 |