loxoprofen has been researched along with Bradyarrhythmia in 2 studies
loxoprofen: RN given refers to parent cpd without isomeric designation; structure in first source
loxoprofen : A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-[(2-oxocyclopentyl)methyl]phenyl group. A prodrug that is rapidly converted into its active trans-alcohol metabolite following oral administration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 37-year-old man suffered irreversible profound symptomatic bradycardia requiring a pacemaker 3 days after beginning tizanidine/loxoprofen combination therapy for neck pain." | 7.88 | Irreversible profound symptomatic bradycardia requiring pacemaker after tizanidine/loxoprofen combination therapy: a case report. ( Jin, Y; Li, X, 2018) |
| "A 37-year-old man suffered irreversible profound symptomatic bradycardia requiring a pacemaker 3 days after beginning tizanidine/loxoprofen combination therapy for neck pain." | 3.88 | Irreversible profound symptomatic bradycardia requiring pacemaker after tizanidine/loxoprofen combination therapy: a case report. ( Jin, Y; Li, X, 2018) |
| " The cause of hyperkalemia was considered to be several doses of loxoprofen, a nonsteroidal anti-inflammatory drug (NSAID), prescribed for her lumbago by an orthopedic specialist, in addition to the long-term intake of imidapril, an angiotensin-converting enzyme inhibitor (ACEI), prescribed for her hypertension by a cardiologist." | 3.70 | Syncope caused by nonsteroidal anti-inflammatory drugs and angiotensin-converting enzyme inhibitors. ( Kurata, C; Sugi, T; Uehara, A; Yamazaki, K, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, X | 1 |
| Jin, Y | 1 |
| Kurata, C | 1 |
| Uehara, A | 1 |
| Sugi, T | 1 |
| Yamazaki, K | 1 |
2 other studies available for loxoprofen and Bradyarrhythmia
| Article | Year |
|---|---|
Irreversible profound symptomatic bradycardia requiring pacemaker after tizanidine/loxoprofen combination therapy: a case report.
Topics: Adult; Analgesics; Atrioventricular Block; Bradycardia; Cardiac Pacing, Artificial; Clonidine; Drug | 2018 |
Syncope caused by nonsteroidal anti-inflammatory drugs and angiotensin-converting enzyme inhibitors.
Topics: Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Ste | 1999 |