Page last updated: 2024-08-23

lovastatin and Pancreatic Neoplasms

lovastatin has been researched along with Pancreatic Neoplasms in 20 studies

Research

Studies (20)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (5.00)	18.7374
1990's	6 (30.00)	18.2507
2000's	5 (25.00)	29.6817
2010's	6 (30.00)	24.3611
2020's	2 (10.00)	2.80

Authors

Authors	Studies
Deng, M; Qi, C; Qiao, Y; Shi, Z; Sun, W; Tao, L; Xie, S; Zhang, Y	1
Brunicardi, FC; Chen, C; Chen, F; Kong, D; Li, Z; Liu, SH; Luo, H; Shui, J; Wang, K; Wu, H; Xu, Y; Yu, J; Zhang, Z; Zou, L	1
Banerjee, S; Bhattacharya, S; Dauer, P; Dudeja, V; Giri, B; Gupta, VK; Kesh, K; Nomura, A; Saluja, A; Sharma, NS	1
Chang, J; Cooper, RM; Difronzo, AL; Huang, B; Jeon, CY; Ngor, EW; Pandol, SJ; Wu, BU	1
Archibugi, L; Capurso, G; Delle Fave, G	1
Chang, JI; Huang, BZ; Li, E; Wu, BU; Xiang, AH	1
Hussein, D; Mo, H	1
Chiba, Y; Fukamachi, T; Kobayashi, H; Saito, H; Tagawa, M; Wang, X	1
Corinaldesi, R; Morselli-Labate, AM; Pezzilli, R	1
Chan, CF; Cheng, AL; Chuang, SE; Lai, GM; Yang, YY; Yao, CJ	1
Bil, J; Brzezinska, A; Gietka, J; Golab, J; Issat, T; Jakóbisiak, M; Klejman, MP; Koronkiewicz, M; Legat, M; Makowski, M; Nowis, D; Skierski, J; Stoklosa, T; Urbanski, J	1
Kottapally, S; Rao, KN; Shinozuka, H	1
Beauchamp, RD; Ishizuka, J; Pour, PM; Sumi, S; Thompson, JC; Townsend, CM	1
Namiki, M; Nishino, N; Obara, T; Okamura, K; Tanno, S; Ura, H	1
Hamilton, AD; Qian, Y; Sebti, SM; Sun, J; Vogt, A	1
Bockhorn, AG; Kalthoff, H; Kiehl, M; Klusmeier, S; Koch, OM; Müller, C; Roeder, C	1
Jamieson, JD; Qiu, X; Valentijn, JA	1
Akedo, H; Inoue, M; Iwasaki, T; Kusama, T; Matsumoto, Y; Mukai, M; Nakamura, H; Tatsuta, M	1
Beauchamp, RD; Ishizuka, J; Murakami, M; Rajaraman, S; Sumi, S; Thompson, JC; Townsend, CM; Uchida, T	1
Darzynkiewicz, Z; Mikulski, SM; Shogen, K; Viera, A	1

Other Studies

20 other study(ies) available for lovastatin and Pancreatic Neoplasms

Article	Year
New cytotoxic secondary metabolites against human pancreatic cancer cells from the Hypericum perforatum endophytic fungus Aspergillus terreus. Fitoterapia, 2020, Volume: 146 Topics: 4-Butyrolactone; Antineoplastic Agents; Aspergillus; Cell Line, Tumor; China; Flowers; Humans; Hypericum; Lovastatin; Pancreatic Neoplasms	2020
Transcriptome sequencing analysis reveals unique and shared antitumor effects of three statins in pancreatic cancer. Oncology reports, 2020, Volume: 44, Issue:6 Topics: Autophagy; Cell Cycle; Cell Line, Tumor; Cyclin A2; DNA Replication; Drug Screening Assays, Antitumor; Fluvastatin; Gene Expression Regulation, Neoplastic; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Pancreatic Neoplasms; RNA-Seq; Signal Transduction; Simvastatin; Transcriptome	2020
Metastasis and chemoresistance in CD133 expressing pancreatic cancer cells are dependent on their lipid raft integrity. Cancer letters, 2018, 12-28, Volume: 439 Topics: AC133 Antigen; Animals; Caveolin 1; Cell Line, Tumor; Cholesterol; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Membrane Microdomains; Mice, Inbred C57BL; Mice, Nude; Neoplasm Metastasis; Neoplastic Stem Cells; Paclitaxel; Pancreatic Neoplasms; Xenograft Model Antitumor Assays	2018
Impact of statin use on survival in patients undergoing resection for early-stage pancreatic cancer. The American journal of gastroenterology, 2015, Volume: 110, Issue:8 Topics: Aged; Carcinoma, Pancreatic Ductal; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kaplan-Meier Estimate; Lovastatin; Male; Middle Aged; Neoplasm Staging; Pancreatic Neoplasms; Proportional Hazards Models; Retrospective Studies; Simvastatin; Survival Rate	2015
Statin Use and Survival in Resectable Pancreatic Cancer: Confounders and Mechanisms. The American journal of gastroenterology, 2016, Volume: 111, Issue:3 Topics: Carcinoma, Pancreatic Ductal; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Pancreatic Neoplasms; Simvastatin	2016
Influence of Statins and Cholesterol on Mortality Among Patients With Pancreatic Cancer. Journal of the National Cancer Institute, 2017, Volume: 109, Issue:5 Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Atorvastatin; California; Carcinoma, Pancreatic Ductal; Cholesterol, LDL; Deoxycytidine; Drug Prescriptions; Female; Gemcitabine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Middle Aged; Pancreatic Neoplasms; Pravastatin; Proportional Hazards Models; Retrospective Studies; Rosuvastatin Calcium; Simvastatin; Survival Rate	2017
d-δ-Tocotrienol-mediated suppression of the proliferation of human PANC-1, MIA PaCa-2, and BxPC-3 pancreatic carcinoma cells. Pancreas, 2009, Volume: 38, Issue:4 Topics: Adenocarcinoma; Apoptosis; Carcinoma, Pancreatic Ductal; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Synergism; Flow Cytometry; G1 Phase; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inhibitory Concentration 50; Lovastatin; Mevalonic Acid; Microscopy, Fluorescence; Pancreatic Neoplasms; Tocotrienols	2009
Tumor specific low pH environments enhance the cytotoxicity of lovastatin and cantharidin. Cancer letters, 2010, Nov-28, Volume: 297, Issue:2 Topics: Cantharidin; Cell Growth Processes; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme Inhibitors; HeLa Cells; Humans; Hydrogen-Ion Concentration; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mesothelioma; Pancreatic Neoplasms	2010
Medical therapy for advanced pancreatic cancer: work in progress. JOP : Journal of the pancreas, 2011, Jan-05, Volume: 12, Issue:1 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antineoplastic Agents; Biomedical Research; Chemokine CXCL12; Deoxycytidine; Drug Resistance, Neoplasm; Drug Therapy, Combination; Gemcitabine; Humans; Hydrogen-Ion Concentration; Losartan; Lovastatin; Pancreatic Neoplasms; Treatment Outcome	2011
Dramatic synergistic anticancer effect of clinically achievable doses of lovastatin and troglitazone. International journal of cancer, 2006, Feb-01, Volume: 118, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Survival; Chromans; Cyclin A; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p27; Dose-Response Relationship, Drug; Drug Synergism; E2F1 Transcription Factor; Glioblastoma; HeLa Cells; Humans; Lovastatin; Lung Neoplasms; Male; Pancreatic Neoplasms; Phosphorylation; Prostatic Neoplasms; Retinoblastoma Protein; Thiazolidinediones; Troglitazone; Tumor Cells, Cultured	2006
Potentiated antitumor effects of the combination treatment with statins and pamidronate in vitro and in vivo. International journal of oncology, 2007, Volume: 30, Issue:6 Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Cell Adhesion; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Diphosphonates; Drug Synergism; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Lovastatin; Mice; Pamidronate; Pancreatic Neoplasms	2007
Acinar cell carcinoma of rat pancreas: mechanism of deregulation of cholesterol metabolism. Toxicologic pathology, 1984, Volume: 12, Issue:1 Topics: Animals; Cells, Cultured; Cholesterol; Cholesterol, Dietary; DNA; Female; Glucosephosphate Dehydrogenase; Injections, Intraperitoneal; Liver; Lovastatin; Male; Mice; Mice, Inbred BALB C; Naphthalenes; Pancreatic Neoplasms; Rats; Rats, Inbred Strains; Receptors, LDL	1984
Lovastatin inhibits pancreatic cancer growth regardless of RAS mutation. Pancreas, 1994, Volume: 9, Issue:5 Topics: Animals; Base Sequence; Cell Division; Cricetinae; Genes, ras; Humans; Lovastatin; Molecular Sequence Data; Pancreatic Neoplasms; Point Mutation	1994
Cytotoxicity of simvastatin to pancreatic adenocarcinoma cells containing mutant ras gene. Japanese journal of cancer research : Gann, 1994, Volume: 85, Issue:6 Topics: Adenocarcinoma; Animals; Base Sequence; Cell Cycle; Codon; Cricetinae; DNA, Neoplasm; Genes, ras; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Molecular Sequence Data; Pancreatic Neoplasms; Point Mutation; Protein Prenylation; Proto-Oncogene Proteins p21(ras); Sensitivity and Specificity; Simvastatin; Tumor Cells, Cultured	1994
The geranylgeranyltransferase-I inhibitor GGTI-298 arrests human tumor cells in G0/G1 and induces p21(WAF1/CIP1/SDI1) in a p53-independent manner. The Journal of biological chemistry, 1997, Oct-24, Volume: 272, Issue:43 Topics: Alkyl and Aryl Transferases; Benzamides; Breast Neoplasms; Cell Cycle; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Enzyme Inhibitors; Female; Fibrosarcoma; G1 Phase; Head and Neck Neoplasms; Humans; Lovastatin; Methionine; Oligopeptides; Pancreatic Neoplasms; Protein Prenylation; Resting Phase, Cell Cycle; Tumor Suppressor Protein p53; Urinary Bladder Neoplasms	1997
Lovastatin inhibits proliferation of pancreatic cancer cell lines with mutant as well as with wild-type K-ras oncogene but has different effects on protein phosphorylation and induction of apoptosis. International journal of oncology, 1998, Volume: 12, Issue:3 Topics: Amino Acid Substitution; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Division; Cell Line; Flow Cytometry; Genes, ras; Humans; Lovastatin; Neoplasm Proteins; Pancreatic Neoplasms; Phosphorylation; Point Mutation; Proto-Oncogene Proteins p21(ras); Tumor Cells, Cultured	1998
Carboxyl-methylation of Rab3D in the rat pancreatic acinar tumor cell line AR42J. Biochemical and biophysical research communications, 2001, Jul-20, Volume: 285, Issue:3 Topics: Acetylcysteine; Animals; Antibody Specificity; Cysteine; Dexamethasone; Diterpenes; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoblotting; Isoelectric Focusing; Lovastatin; Methylation; Pancreas; Pancreatic Neoplasms; Protein Isoforms; Protein Methyltransferases; Protein Prenylation; rab3 GTP-Binding Proteins; rab3A GTP-Binding Protein; Rats; Subcellular Fractions; Tumor Cells, Cultured	2001
3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors reduce human pancreatic cancer cell invasion and metastasis. Gastroenterology, 2002, Volume: 122, Issue:2 Topics: Adenocarcinoma; Animals; Cell Division; Cell Membrane; Cytosol; Epidermal Growth Factor; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Liver Neoplasms, Experimental; Lovastatin; Mice; Mice, Nude; Neoplasm Invasiveness; Pancreatic Neoplasms; rhoA GTP-Binding Protein; Tumor Cells, Cultured	2002
Inhibition of pancreatic adenocarcinoma cell growth by lovastatin. Gastroenterology, 1992, Volume: 103, Issue:3 Topics: Animals; Cell Division; Cell Survival; Cricetinae; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; In Vitro Techniques; Lovastatin; Mevalonic Acid; Mice; Mice, Nude; Pancreatic Neoplasms; Time Factors; Transplantation, Heterologous; Tumor Cells, Cultured	1992
Synergism between a novel amphibian oocyte ribonuclease and lovastatin in inducing cytostatic and cytotoxic effects in human lung and pancreatic carcinoma cell lines. British journal of cancer, 1992, Volume: 66, Issue:2 Topics: Adenocarcinoma; Antineoplastic Agents; Cell Division; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Egg Proteins; Humans; Kinetics; Lovastatin; Lung Neoplasms; Mevalonic Acid; Oocytes; Pancreatic Neoplasms; Ribonucleases	1992