Page last updated: 2024-08-23

lovastatin and Multiple Sclerosis

lovastatin has been researched along with Multiple Sclerosis in 10 studies

Research

Studies (10)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	9 (90.00)	29.6817
2010's	1 (10.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bartosik-Psujek, H; Pocinska, K; Radej, S; Rolinski, J; Stelmasiak, Z; Tabarkiewicz, J	1
Graça Morais, M; Pedrosa, R; Sena, A	1
Archelos, JJ; Hartung, HP; Kieseier, BC; Neuhaus, O; Wiendl, H	1
Giri, S; Nath, N; Prasad, R; Singh, AK; Singh, I	1
Barbosa, E; Gilg, AG; Paintlia, AS; Paintlia, MK; Singh, AK; Singh, I; Stanislaus, R	1
Khan, M; Paintlia, AS; Paintlia, MK; Singh, AK; Singh, I; Vollmer, T	1
Auger, C; Bernard, M; Bouthillier, A; Cayrol, R; Duquette, P; Ifergan, I; Kébir, H; Moumdjian, R; Prat, A; Wosik, K	1
Paintlia, AS; Paintlia, MK; Singh, AK; Singh, I	1
Morais, MG; Pedrosa, R; Sena, A	1
Singh, AK; Singh, I; Stanislaus, R	1

Reviews

1 review(s) available for lovastatin and Multiple Sclerosis

Article	Year
[Cholesterol-reducing medications-a new therapeutic option for multiple sclerosis? Statins as immunomodulators]. Der Nervenarzt, 2003, Volume: 74, Issue:8 Topics: Adjuvants, Immunologic; Anticholesteremic Agents; Cholesterol; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Multiple Sclerosis	2003

Trials

1 trial(s) available for lovastatin and Multiple Sclerosis

Article	Year
Beneficial effect of statins in multiple sclerosis: is it dose-dependent? Atherosclerosis, 2007, Volume: 191, Issue:2 Topics: Atorvastatin; Dose-Response Relationship, Drug; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunologic Factors; Lovastatin; Multiple Sclerosis; Pyrroles; Simvastatin; Treatment Outcome	2007

Other Studies

8 other study(ies) available for lovastatin and Multiple Sclerosis

Article	Year
Immunomodulatory effects of IFN-beta and lovastatin on immunophenotype of monocyte-derived dendritic cells in multiple sclerosis. Archivum immunologiae et therapiae experimentalis, 2010, Volume: 58, Issue:4 Topics: Adult; Anticholesteremic Agents; Antigens, CD; Dendritic Cells; Female; Humans; Immunologic Factors; Immunophenotyping; Interferon-beta; Lovastatin; Male; Middle Aged; Monocytes; Multiple Sclerosis; Tumor Necrosis Factor-alpha; Young Adult	2010
Therapeutic potential of lovastatin in multiple sclerosis. Journal of neurology, 2003, Volume: 250, Issue:6 Topics: Adult; Disability Evaluation; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Magnetic Resonance Imaging; Middle Aged; Multiple Sclerosis; Pilot Projects; Recurrence	2003
Potential targets of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor for multiple sclerosis therapy. Journal of immunology (Baltimore, Md. : 1950), 2004, Jan-15, Volume: 172, Issue:2 Topics: Animals; Cell Differentiation; Cell Line; Cell Migration Inhibition; Cell Movement; DNA-Binding Proteins; Encephalomyelitis, Autoimmune, Experimental; Epitopes, T-Lymphocyte; Female; GATA3 Transcription Factor; Growth Inhibitors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Injections, Intraperitoneal; Interphase; Lovastatin; Mice; Mice, Inbred Strains; Multiple Sclerosis; Myelin Proteolipid Protein; Neurons; Spinal Cord; T-Box Domain Proteins; T-Lymphocyte Subsets; Th1 Cells; Th2 Cells; Trans-Activators; Transcription Factors; Up-Regulation	2004
Regulation of gene expression associated with acute experimental autoimmune encephalomyelitis by Lovastatin. Journal of neuroscience research, 2004, Jul-01, Volume: 77, Issue:1 Topics: Animals; Cytokines; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Gene Expression Regulation; Genes, MHC Class II; Growth Substances; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Multiple Sclerosis; Oligonucleotide Array Sequence Analysis; Rats; Rats, Inbred Lew; RNA, Messenger; Severity of Illness Index; Spinal Cord; Transcription Factors; Up-Regulation	2004
HMG-CoA reductase inhibitor augments survival and differentiation of oligodendrocyte progenitors in animal model of multiple sclerosis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2005, Volume: 19, Issue:11 Topics: Animals; Cell Differentiation; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Multiple Sclerosis; Myelin Sheath; Oligodendroglia; Rats; Rats, Inbred Lew; Stem Cells	2005
Statins reduce human blood-brain barrier permeability and restrict leukocyte migration: relevance to multiple sclerosis. Annals of neurology, 2006, Volume: 60, Issue:1 Topics: Adult; Blood-Brain Barrier; Capillary Permeability; Cell Movement; Cells, Cultured; Chemokine CCL2; Chemokine CXCL10; Chemokines, CXC; Endothelial Cells; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Leukocytes; Lovastatin; Male; Membrane Proteins; Monocytes; Multiple Sclerosis; Occludin; Phosphoproteins; Protein Prenylation; Simvastatin; Tight Junctions; Zonula Occludens-1 Protein	2006
Immunomodulatory effect of combination therapy with lovastatin and 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside alleviates neurodegeneration in experimental autoimmune encephalomyelitis. The American journal of pathology, 2006, Volume: 169, Issue:3 Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Therapy, Combination; Encephalomyelitis, Autoimmune, Experimental; Enzyme Activation; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Immunoglobulin G; Immunologic Factors; Lovastatin; Multienzyme Complexes; Multiple Sclerosis; Myelin Basic Protein; Protein Serine-Threonine Kinases; Rats; Rats, Inbred Lew; Ribonucleotides; Th1 Cells; Th2 Cells	2006
Lovastatin treatment decreases mononuclear cell infiltration into the CNS of Lewis rats with experimental allergic encephalomyelitis. Journal of neuroscience research, 2001, Oct-15, Volume: 66, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Adhesion; Chemotaxis, Leukocyte; Cytokines; Demyelinating Diseases; Disease Models, Animal; Drug Evaluation, Preclinical; Encephalomyelitis, Autoimmune, Experimental; Endothelium, Vascular; Enzyme Induction; Female; Gene Expression Regulation; Intercellular Adhesion Molecule-1; Lovastatin; Lymphocyte Function-Associated Antigen-1; Monocytes; Multiple Sclerosis; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Inbred Lew; Spinal Cord	2001