lovastatin has been researched along with Malignant Melanoma in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 4 (36.36) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barr, RJ; Carpenter, PM; Chen, WP; Cochran, AJ; Elmets, CA; Jakowatz, JG; Leachman, SA; Lim, SJ; Linden, KG; McLaren, CE; Meyskens, FL; Tangrea, JA; Viner, JL; Zager, JS | 1 |
| Hohenegger, M; Minichsdorfer, C | 1 |
| Dellavalle, RP; Gendall, J; Kelly, D; Miller, L; Norris, DA; Ribble, D; Shellman, YG; Vanbuskirk, K | 1 |
| Dellavalle, RP; Drake, AL; Freeman, SR; Graber, M; Heilig, LF; McNealy, K; Schilling, LM | 1 |
| Clynes, M; Eustace, AJ; Glynn, SA; O'Donovan, N; O'Sullivan, D | 1 |
| Blegen, H; Carlberg, M; Dricu, A; Hjertman, M; Höög, A; Larsson, O; Wang, M; Zickert, P | 1 |
| Beery, E; Goldwasser, I; Nordenberg, J; Sidi, Y; Zoref-Shani, E | 1 |
| Blegen, H; Carlberg, M; Dricu, A; Hjertman, M; Larsson, O; Malec, M; Wang, M; Wejde, J | 1 |
| Mikhailidis, DP; Papadakis, JA | 1 |
| Gershenwald, JE | 1 |
| Melnykovych, G; Ramachandran, CK; Sanders, K | 1 |
1 review(s) available for lovastatin and Malignant Melanoma
| Article | Year |
|---|---|
Statins, fibrates, and melanoma risk: a systematic review and meta-analysis.
Topics: Atorvastatin; Bezafibrate; Clofibrate; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Incidence; Lovastatin; Melanoma; Odds Ratio; Pravastatin; Pyrroles; Randomized Controlled Trials as Topic; Reproducibility of Results; Simvastatin; Skin Neoplasms; United States | 2006 |
1 trial(s) available for lovastatin and Malignant Melanoma
| Article | Year |
|---|---|
A randomized, double-blind, placebo-controlled phase II clinical trial of lovastatin for various endpoints of melanoma pathobiology.
Topics: Adult; Anticholesteremic Agents; Biomarkers, Tumor; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Lovastatin; Male; Melanoma; Middle Aged; Nevus; Placebos; Skin Neoplasms | 2014 |
9 other study(ies) available for lovastatin and Malignant Melanoma
| Article | Year |
|---|---|
Autocrine amplification loop in statin-induced apoptosis of human melanoma cells.
Topics: Antineoplastic Agents; Apoptosis; Atorvastatin; Autocrine Communication; Biological Factors; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Enzyme Activation; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Melanoma; Pyridines; Pyrroles; Simvastatin; Time Factors | 2009 |
Lovastatin-induced apoptosis in human melanoma cell lines.
Topics: Animals; Anticholesteremic Agents; Apoptosis; Carcinoma, Squamous Cell; Caspase 3; Caspases; Cell Proliferation; Dimethylallyltranstransferase; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Melanoma; Mice; Polyisoprenyl Phosphates; Pravastatin; Sesquiterpenes | 2005 |
The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells.
Topics: Apoptosis; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Lovastatin; Lung Neoplasms; Male; Melanoma; Neoplasm Invasiveness; Simvastatin; Skin Neoplasms | 2008 |
Mevalonic acid is limiting for N-linked glycosylation and translocation of the insulin-like growth factor-1 receptor to the cell surface. Evidence for a new link between 3-hydroxy-3-methylglutaryl-coenzyme a reductase and cell growth.
Topics: Base Sequence; Cell Division; Cell Line; Cell Membrane; Colonic Neoplasms; DNA Primers; DNA, Neoplasm; Dolichol Phosphates; Enzyme Inhibitors; Gene Expression; Glycosylation; Growth Substances; Hepatoblastoma; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin; Insulin-Like Growth Factor I; Kinetics; Liver Neoplasms; Lovastatin; Melanoma; Mevalonic Acid; Models, Biological; Molecular Sequence Data; Oligonucleotides, Antisense; Protein Processing, Post-Translational; Receptor, IGF Type 1; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1996 |
Inhibition of B16 melanoma cell proliferation and alterations in p21 ras expression induced by interceptors of signal transduction pathways.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antineoplastic Agents; Cell Division; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Lovastatin; Melanoma; Proto-Oncogene Proteins p21(ras); Ribavirin; Signal Transduction; Tumor Cells, Cultured | 1996 |
Mevalonate-regulated mechanisms in cell growth control: role of dolichyl phosphate in expression of the insulin-like growth factor-1 receptor (IGF-1R) in comparison to Ras prenylation and expression of c-myc.
Topics: Cell Division; Cell Membrane; Colonic Neoplasms; DNA, Neoplasm; Dolichol Phosphates; Glycosylation; Humans; Kinetics; Lovastatin; Melanoma; Mevalonic Acid; Neoplasm Proteins; Polymerase Chain Reaction; Protein Prenylation; ras Proteins; Receptor, IGF Type 1; Skin Neoplasms; Tumor Cells, Cultured | 1997 |
Coronary events with lipid-lowering therapy: the AFCAPS/TexCAPS trial. Air Force/Texas Coronary Atherosclerosis Prevention Study.
Topics: Anticholesteremic Agents; Antineoplastic Agents; Coronary Disease; Humans; Lovastatin; Melanoma | 1999 |
Melanoma.
Topics: Antineoplastic Agents; Cancer Vaccines; Chemoprevention; Chemotherapy, Adjuvant; Humans; Interferons; Lovastatin; Melanoma; Neoplasm Staging; Randomized Controlled Trials as Topic; Sentinel Lymph Node Biopsy | 2001 |
Enhancement in the adhesion of tumor cells to endothelial cells by decreased cholesterol synthesis.
Topics: Animals; Anticholesteremic Agents; Cattle; Cell Adhesion; Cells, Cultured; Cholesterol; Dexamethasone; Endothelium; Hydroxycholesterols; Ketocholesterols; Lovastatin; Melanoma; Membrane Fluidity; Membrane Lipids; Mice; Microscopy, Electron, Scanning; Naphthalenes; Retinoids | 1986 |