Page last updated: 2024-08-23

lovastatin and Lung Neoplasms

lovastatin has been researched along with Lung Neoplasms in 25 studies

Research

Studies (25)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	5 (20.00)	18.2507
2000's	10 (40.00)	29.6817
2010's	9 (36.00)	24.3611
2020's	1 (4.00)	2.80

Authors

Authors	Studies
Aksoy, HN; Ceylan, C	1
Beeson, CC; Beeson, GC; Christie, CF; Fang, D; Heslop, KA; Hunt, EG; Maldonado, EN; Morris, ME; Rovini, A	1
Anver, M; Bullova, P; Fliedner, S; Giubellino, A; Göke, B; Grossman, A; Korbonits, M; Lauseker, M; Nölting, S; Pacak, K; Schovanek, J; Tayem, Y; Vlotides, G; Young, K	1
Kao, CH; Lin, CL; Lin, WM; Sung, FC; Yang, TY	1
Chen, GY; Gao, YN; Hong, X; Teng, Y; Wang, M; Yang, F; Ye, LG; Zhang, X	1
Chang, VH; Chen, CC; Jiang, X; Lin, HY; Liu, YR; Wang, J; Yang, SH; Yen, Y; Zhang, K	1
Emmrich, K; Hinz, B; Mittag, N; Ramer, R; Walther, U	1
Ho, BY; Pan, TM	1
Han, JY; Jung, JI; Kim, JY; Park, IH	1
Bradbury, PA; Dimitroulakos, J; Ding, K; Goss, G; Le Francois, BG; Zhao, TT	1
Farrell, T; Hopmans, SN; Liu, C; Rashid, A; Sanli, T; Schultz, C; Singh, G; Tsakiridis, T; Tsiani, E; Wright, J	1
Alonso, DF; Bublik, DR; Farina, HG; Gomez, DE	1
Corey, DA; Kelley, TJ; Kraynack, NC; Kreiselmeier, NE	1
Ito, Y; Morimoto, J; Otsuki, Y; Shibata, MA	1
Dimitroulakos, J; Goss, G; Hanson, JE; Lagarde, AE; Lorimer, IA; Mantha, AJ	1
Chan, CF; Cheng, AL; Chuang, SE; Lai, GM; Yang, YY; Yao, CJ	1
Kenna, T; Mattarollo, SR; Nicol, AJ; Nieda, M	1
Clynes, M; Eustace, AJ; Glynn, SA; O'Donovan, N; O'Sullivan, D	1
Cowan, KH; Gudas, JM; He, R; Moscow, JA	1
Bennis, F; Favre, G; Le Gaillard, F; Soula, G	1
Cesen, KT; Hawk, MA; Ruch, RJ; Siglin, JC; Stoner, GD	1
de Bravo, MG; Polo, M; Schinella, G; Tournier, H	1
Chen, Z; Jia, Z; Moyana, T; Saxena, A; Warrington, R; Xiang, J	1
Dabrowska, A; Feleszko, W; Giermasz, A; Gołab, J; Jakóbisiak, M; Jalili, A; Kozłowska, E; Maj, M; Makowski, M; Nowis, D; Wójcik, C	1
Darzynkiewicz, Z; Mikulski, SM; Shogen, K; Viera, A	1

Other Studies

25 other study(ies) available for lovastatin and Lung Neoplasms

Article	Year
Comparison of the Effects of Statins on A549 Nonsmall-Cell Lung Cancer Cell Line Lipids Using Fourier Transform Infrared Spectroscopy: Rosuvastatin Stands Out. Lipids, 2021, Volume: 56, Issue:3 Topics: A549 Cells; Atorvastatin; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Metabolism; Lipids; Lovastatin; Lung Neoplasms; Pravastatin; Rosuvastatin Calcium; Simvastatin; Spectroscopy, Fourier Transform Infrared	2021
Statin-dependent modulation of mitochondrial metabolism in cancer cells is independent of cholesterol content. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019, Volume: 33, Issue:7 Topics: Adenocarcinoma of Lung; Carcinoma, Hepatocellular; Hep G2 Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver Neoplasms; Lovastatin; Lung Neoplasms; Membrane Potential, Mitochondrial; Mitochondria, Liver; Simvastatin	2019
Combination of 13-Cis retinoic acid and lovastatin: marked antitumor potential in vivo in a pheochromocytoma allograft model in female athymic nude mice. Endocrinology, 2014, Volume: 155, Issue:7 Topics: Actins; Adrenal Gland Neoplasms; Animals; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Survival; Chromogranin A; Female; Immunohistochemistry; Isotretinoin; Lovastatin; Lung Neoplasms; Mice; Mice, Nude; Muscle, Smooth; Pheochromocytoma; Time Factors; Transplantation, Homologous; Treatment Outcome; Tumor Burden; Tyrosine 3-Monooxygenase	2014
Correlation between use of simvastatin and lovastatin and female lung cancer risk: a nationwide case-control study. International journal of clinical practice, 2015, Volume: 69, Issue:5 Topics: Administration, Oral; Adult; Aged; Case-Control Studies; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Lung Neoplasms; Middle Aged; Registries; Risk Factors; Simvastatin; Taiwan; Women's Health; Young Adult	2015
MCM2 is a therapeutic target of lovastatin in human non-small cell lung carcinomas. Oncology reports, 2015, Volume: 33, Issue:5 Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line, Tumor; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; G1 Phase Cell Cycle Checkpoints; Humans; Lovastatin; Lung Neoplasms; MAP Kinase Signaling System; Minichromosome Maintenance Complex Component 2; Retinoblastoma Protein; Tumor Suppressor Protein p53	2015
Lovastatin overcomes gefitinib resistance through TNF-α signaling in human cholangiocarcinomas with different LKB1 statuses in vitro and in vivo. Oncotarget, 2015, Sep-15, Volume: 6, Issue:27 Topics: AMP-Activated Protein Kinase Kinases; Animals; Antineoplastic Agents; Apoptosis; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cholangiocarcinoma; Drug Resistance, Neoplasm; Drug Synergism; Gefitinib; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Lung Neoplasms; Male; Mice; Mice, Inbred ICR; Protein Serine-Threonine Kinases; Quinazolines; RNA Interference; RNA, Small Interfering; Signal Transduction; Tumor Necrosis Factor-alpha; Xenograft Model Antitumor Assays	2015
Lovastatin lactone elicits human lung cancer cell apoptosis via a COX-2/PPARγ-dependent pathway. Oncotarget, 2016, Mar-01, Volume: 7, Issue:9 Topics: A549 Cells; Anilides; Apoptosis; Cell Line, Tumor; Cell Survival; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; DNA Fragmentation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Lung Neoplasms; Nitrobenzenes; PPAR gamma; Prostaglandin D2; RNA Interference; RNA, Messenger; RNA, Small Interfering; Sulfonamides	2016
The Monascus metabolite monacolin K reduces tumor progression and metastasis of Lewis lung carcinoma cells. Journal of agricultural and food chemistry, 2009, Sep-23, Volume: 57, Issue:18 Topics: Animals; Carcinoma, Lewis Lung; Fermentation; Lovastatin; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Monascus; Neoplasm Metastasis; Oryza; Plant Extracts; Reverse Transcriptase Polymerase Chain Reaction; Vascular Endothelial Growth Factor A	2009
Lovastatin overcomes gefitinib resistance in human non-small cell lung cancer cells with K-Ras mutations. Investigational new drugs, 2010, Volume: 28, Issue:6 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; ErbB Receptors; Gefitinib; Humans; Lovastatin; Lung Neoplasms; Mutation; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Quinazolines; ras Proteins; Signal Transduction	2010
Lovastatin inhibits EGFR dimerization and AKT activation in squamous cell carcinoma cells: potential regulation by targeting rho proteins. Oncogene, 2010, Aug-19, Volume: 29, Issue:33 Topics: Amides; Animals; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cell Line, Tumor; Cytoskeleton; Dimerization; Drug Interactions; Enzyme Activation; ErbB Receptors; Head and Neck Neoplasms; Humans; Lovastatin; Lung Neoplasms; Mice; NIH 3T3 Cells; Polyisoprenyl Phosphates; Proto-Oncogene Proteins c-akt; Pyridines; rho-Associated Kinases; Signal Transduction	2010
Lovastatin sensitizes lung cancer cells to ionizing radiation: modulation of molecular pathways of radioresistance and tumor suppression. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2011, Volume: 6, Issue:3 Topics: Adenocarcinoma; Apoptosis; Blotting, Western; Cell Cycle; Cell Proliferation; Cytoprotection; Fluorescent Antibody Technique; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Lung Neoplasms; Radiation Tolerance; Radiation, Ionizing; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured	2011
Lovastatin alters cytoskeleton organization and inhibits experimental metastasis of mammary carcinoma cells. Clinical & experimental metastasis, 2002, Volume: 19, Issue:6 Topics: Animals; Antineoplastic Agents; Cytoskeleton; Lovastatin; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Tumor Cells, Cultured	2002
Statin-mediated correction of STAT1 signaling and inducible nitric oxide synthase expression in cystic fibrosis epithelial cells. American journal of physiology. Lung cellular and molecular physiology, 2003, Volume: 285, Issue:6 Topics: Adenocarcinoma, Bronchiolo-Alveolar; Anticholesteremic Agents; Cell Line, Tumor; Cholesterol; Cystic Fibrosis; DNA-Binding Proteins; Gene Expression Regulation, Enzymologic; Humans; Lovastatin; Lung Neoplasms; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Protein Inhibitors of Activated STAT; Proteins; Respiratory Mucosa; rhoA GTP-Binding Protein; Signal Transduction; STAT1 Transcription Factor; Terpenes; Trans-Activators	2003
Lovastatin inhibits tumor growth and lung metastasis in mouse mammary carcinoma model: a p53-independent mitochondrial-mediated apoptotic mechanism. Carcinogenesis, 2004, Volume: 25, Issue:10 Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Caspase Inhibitors; Caspases; Cell Cycle; Cytochromes c; Disease Models, Animal; Enzyme Inhibitors; Female; Flow Cytometry; In Situ Nick-End Labeling; Lovastatin; Lung Neoplasms; Mammary Neoplasms, Experimental; Membrane Potentials; Mice; Mice, Inbred BALB C; Microscopy, Electron; Mitochondria; Mutation; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Tumor Suppressor Protein p53	2004
Targeting the mevalonate pathway inhibits the function of the epidermal growth factor receptor. Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Mar-15, Volume: 11, Issue:6 Topics: Adenosine Triphosphate; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Binding Sites; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Colonic Neoplasms; Drug Synergism; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Gefitinib; Humans; Lovastatin; Lung Neoplasms; Mevalonic Acid; Mitogen-Activated Protein Kinases; Mutation; Phosphorylation; Quinazolines; Signal Transduction; Tumor Cells, Cultured	2005
Dramatic synergistic anticancer effect of clinically achievable doses of lovastatin and troglitazone. International journal of cancer, 2006, Feb-01, Volume: 118, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Survival; Chromans; Cyclin A; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p27; Dose-Response Relationship, Drug; Drug Synergism; E2F1 Transcription Factor; Glioblastoma; HeLa Cells; Humans; Lovastatin; Lung Neoplasms; Male; Pancreatic Neoplasms; Phosphorylation; Prostatic Neoplasms; Retinoblastoma Protein; Thiazolidinediones; Troglitazone; Tumor Cells, Cultured	2006
Chemotherapy and zoledronate sensitize solid tumour cells to Vgamma9Vdelta2 T cell cytotoxicity. Cancer immunology, immunotherapy : CII, 2007, Volume: 56, Issue:8 Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Burkitt Lymphoma; Carcinoma; Cell Line, Tumor; Cisplatin; Colorectal Neoplasms; Concanavalin A; Cytotoxicity, Immunologic; Diphosphonates; Doxorubicin; Drug Screening Assays, Antitumor; Drug Synergism; Etoposide; Female; Genes, T-Cell Receptor delta; Genes, T-Cell Receptor gamma; Humans; Imidazoles; Interferon-gamma; Lovastatin; Lung Neoplasms; Male; Membrane Glycoproteins; Neoplasms; Perforin; Pore Forming Cytotoxic Proteins; Prostatic Neoplasms; Receptors, Antigen, T-Cell, gamma-delta; T-Lymphocyte Subsets; Urinary Bladder Neoplasms; Vincristine; Zoledronic Acid	2007
The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells. BMC cancer, 2008, Jan-16, Volume: 8 Topics: Apoptosis; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Lovastatin; Lung Neoplasms; Male; Melanoma; Neoplasm Invasiveness; Simvastatin; Skin Neoplasms	2008
Utilization of multiple polyadenylation signals in the human RHOA protooncogene. Gene, 1994, Jul-08, Volume: 144, Issue:2 Topics: Base Sequence; Breast Neoplasms; Colonic Neoplasms; DNA, Complementary; Gene Expression Regulation; GTP-Binding Proteins; Humans; Liver; Lovastatin; Lung Neoplasms; Molecular Sequence Data; Poly A; Proto-Oncogenes; rhoA GTP-Binding Protein; Tissue Distribution; Tumor Cells, Cultured	1994
Importance of mevalonate-derived products in the control of HMG-CoA reductase activity and growth of human lung adenocarcinoma cell line A549. International journal of cancer, 1993, Oct-21, Volume: 55, Issue:4 Topics: Adenocarcinoma; Cholesterol, LDL; Feedback; Humans; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Lovastatin; Lung Neoplasms; Mevalonic Acid	1993
Inhibition of lung tumor cell growth in vitro and mouse lung tumor formation by lovastatin. Cancer letters, 1996, Dec-03, Volume: 109, Issue:1-2 Topics: Animals; Antineoplastic Agents; Carcinogens; Cell Division; Drug Screening Assays, Antitumor; Humans; Lovastatin; Lung Neoplasms; Male; Mice; Mice, Inbred A; Nitrosamines; Tumor Cells, Cultured	1996
Effects of lovastatin on the fatty acid desaturation in a human lung mucoepidermoid carcinoma grown in nude mice. Biochemistry and molecular biology international, 1996, Volume: 38, Issue:5 Topics: Animals; Anticholesteremic Agents; Carcinoma, Mucoepidermoid; Diet; Fatty Acids; Humans; Lovastatin; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental	1996
Efficient antitumor immunity derived from maturation of dendritic cells that had phagocytosed apoptotic/necrotic tumor cells. International journal of cancer, 2001, Aug-15, Volume: 93, Issue:4 Topics: Animals; Antineoplastic Agents; Apoptosis; Cancer Vaccines; Cell Differentiation; Cell Movement; Dendritic Cells; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Interleukin-4; Lovastatin; Lung Neoplasms; Lymphocyte Activation; Melanoma, Experimental; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Necrosis; Phagocytosis; Receptors, CCR7; Receptors, Chemokine; T-Lymphocytes; TRPC Cation Channels; Tumor Cells, Cultured	2001
Potentiating antitumor effects of a combination therapy with lovastatin and butyrate in the Lewis lung carcinoma model in mice. International journal of cancer, 2002, Feb-20, Volume: 97, Issue:6 Topics: Animals; Antineoplastic Agents; Blotting, Western; Carcinoma, Lewis Lung; Cell Cycle; Cell Survival; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Drug Synergism; Drug Therapy, Combination; Female; Flow Cytometry; Formazans; Lovastatin; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Tetrazolium Salts; Triglycerides; Tumor Suppressor Protein p53	2002
Synergism between a novel amphibian oocyte ribonuclease and lovastatin in inducing cytostatic and cytotoxic effects in human lung and pancreatic carcinoma cell lines. British journal of cancer, 1992, Volume: 66, Issue:2 Topics: Adenocarcinoma; Antineoplastic Agents; Cell Division; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Egg Proteins; Humans; Kinetics; Lovastatin; Lung Neoplasms; Mevalonic Acid; Oocytes; Pancreatic Neoplasms; Ribonucleases	1992