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lovastatin and Invasiveness, Neoplasm

lovastatin has been researched along with Invasiveness, Neoplasm in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (27.27)18.2507
2000's5 (45.45)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Afshordel, S; Clasohm, J; Eckert, GP; Kern, B; Kögel, D; König, H; Priester, M; Weissenberger, J1
Gaggioli, C; Hooper, S; Sahai, E1
Asakura, K; Fukutomi, T; Izumi, Y; Kawai, K; Nomori, H; Serizawa, A; Suematsu, M; Wakui, M; Yamauchi, Y1
Chang, TC; Lee, WS; Liang, YC; Wang, CY; Zhong, WB1
Clynes, M; Eustace, AJ; Glynn, SA; O'Donovan, N; O'Sullivan, D1
Binda, MM; Bonfil, RD; Gervasoni, SI; Hinrichsen, LI; Matar, P; Rozados, VR; Scharovsky, OG1
Blanock, K; Gupta, V; Jani, JP; Katoh, A; Singh, SV; Specht, S; Stemmler, N1
Liu, L; Prasanna, P; Samid, D; Thibault, A1
Binda, MM; Bonfil, RD; Matar, P; Roggero, EA; Rozados, VR; Scharovsky, OG1
Lin, JK; Lin-Shiau, SY; Wang, IK1
Akedo, H; Inoue, M; Iwasaki, T; Kusama, T; Matsumoto, Y; Mukai, M; Nakamura, H; Tatsuta, M1

Other Studies

11 other study(ies) available for lovastatin and Invasiveness, Neoplasm

ArticleYear
Lovastatin and perillyl alcohol inhibit glioma cell invasion, migration, and proliferation--impact of Ras-/Rho-prenylation.
    Pharmacological research, 2015, Volume: 91

    Topics: Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cholesterol; Glioma; Humans; Lovastatin; Monoterpenes; Neoplasm Invasiveness; Prenylation; rac1 GTP-Binding Protein; ras Proteins; Terpenes

2015
A chemical biology screen reveals a role for Rab21-mediated control of actomyosin contractility in fibroblast-driven cancer invasion.
    British journal of cancer, 2010, Jan-19, Volume: 102, Issue:2

    Topics: Actomyosin; Carcinoma, Squamous Cell; Extracellular Matrix; Fibroblasts; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Integrin alpha5; Lovastatin; Muscle Contraction; Neoplasm Invasiveness; rab GTP-Binding Proteins; Simvastatin

2010
Lovastatin and valproic acid additively attenuate cell invasion in ACC-MESO-1 cells.
    Biochemical and biophysical research communications, 2011, Jul-01, Volume: 410, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Autophagy; Cell Line, Tumor; Drug Synergism; Humans; Lovastatin; Mesothelioma; Neoplasm Invasiveness; Solitary Fibrous Tumor, Pleural; Valproic Acid

2011
Lovastatin suppresses invasiveness of anaplastic thyroid cancer cells by inhibiting Rho geranylgeranylation and RhoA/ROCK signaling.
    Endocrine-related cancer, 2005, Volume: 12, Issue:3

    Topics: Actins; Antineoplastic Agents; Collagen; Drug Combinations; Flow Cytometry; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Laminin; Lovastatin; Neoplasm Invasiveness; Proteoglycans; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; Signal Transduction; Thyroid Neoplasms; Tumor Cells, Cultured

2005
The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells.
    BMC cancer, 2008, Jan-16, Volume: 8

    Topics: Apoptosis; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Lovastatin; Lung Neoplasms; Male; Melanoma; Neoplasm Invasiveness; Simvastatin; Skin Neoplasms

2008
Lovastatin enhances the antitumoral and apoptotic activity of doxorubicin in murine tumor models.
    Oncology reports, 2008, Volume: 19, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Disease Models, Animal; Doxorubicin; Drug Synergism; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Oligonucleotide Array Sequence Analysis; Rats

2008
Metastasis of B16F10 mouse melanoma inhibited by lovastatin, an inhibitor of cholesterol biosynthesis.
    Invasion & metastasis, 1993, Volume: 13, Issue:6

    Topics: Animals; Cell Adhesion; Cell Division; Female; Lovastatin; Melanoma, Experimental; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Tumor Cells, Cultured

1993
Lipid metabolism as a target for brain cancer therapy: synergistic activity of lovastatin and sodium phenylacetate against human glioma cells.
    Journal of neurochemistry, 1996, Volume: 66, Issue:2

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Division; Drug Synergism; Glioma; Humans; Lipid Metabolism; Lovastatin; Mevalonic Acid; Neoplasm Invasiveness; Phenylacetates; Tumor Cells, Cultured; Ubiquinone

1996
Inhibitory effect of Lovastatin on spontaneous metastases derived from a rat lymphoma.
    Clinical & experimental metastasis, 1999, Volume: 17, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Movement; Cholesterol; Drug Screening Assays, Antitumor; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Lymphoma; Male; Neoplasm Invasiveness; Neovascularization, Pathologic; Rats; Tumor Cells, Cultured

1999
Suppression of invasion and MMP-9 expression in NIH 3T3 and v-H-Ras 3T3 fibroblasts by lovastatin through inhibition of ras isoprenylation.
    Oncology, 2000, Volume: 59, Issue:3

    Topics: 3T3 Cells; Animals; Antineoplastic Agents; Cell Membrane; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Electrophoresis; Gene Expression; Genes, ras; Lovastatin; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mevalonic Acid; Mice; Neoplasm Invasiveness; NF-kappa B; Promoter Regions, Genetic; Protein Prenylation; ras Proteins; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factor AP-1; Transcription, Genetic

2000
3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors reduce human pancreatic cancer cell invasion and metastasis.
    Gastroenterology, 2002, Volume: 122, Issue:2

    Topics: Adenocarcinoma; Animals; Cell Division; Cell Membrane; Cytosol; Epidermal Growth Factor; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Liver Neoplasms, Experimental; Lovastatin; Mice; Mice, Nude; Neoplasm Invasiveness; Pancreatic Neoplasms; rhoA GTP-Binding Protein; Tumor Cells, Cultured

2002