Page last updated: 2024-08-23

lovastatin and Idiopathic Parkinson Disease

lovastatin has been researched along with Idiopathic Parkinson Disease in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's1 (16.67)29.6817
2010's3 (50.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Chang, CH; Chao, YT; Chen, YC; Cheng, MF; Huang, TL; Lin, CH; Tai, CH; Wu, RM; Yen, RF1
Cao, LP; Chen, ML; Chien, CT; Farrer, MJ; Lai, TT; Lin, CH; Lin, HI; Wu, RM1
Bornefall, P; Eriksson, I; Giraldo, AM; Nath, S; Öllinger, K1
Adame, A; Kelly, J; Koob, AO; Mante, M; Masliah, E; Paulsson, JF; Rockenstein, E; Ubhi, K1
Kazis, LE; Lee, A; Lee, TA; Li, NC; Wang, SW; Wolozin, B1
Kuhn, W; Müller, T; Pöhlau, D; Przuntek, H1

Trials

1 trial(s) available for lovastatin and Idiopathic Parkinson Disease

ArticleYear
A Double-Blind, Randomized, Controlled Trial of Lovastatin in Early-Stage Parkinson's Disease.
    Movement disorders : official journal of the Movement Disorder Society, 2021, Volume: 36, Issue:5

    Topics: Double-Blind Method; Follow-Up Studies; Humans; Lovastatin; Mental Status and Dementia Tests; Parkinson Disease

2021

Other Studies

5 other study(ies) available for lovastatin and Idiopathic Parkinson Disease

ArticleYear
Lovastatin protects neurite degeneration in LRRK2-G2019S parkinsonism through activating the Akt/Nrf pathway and inhibiting GSK3β activity.
    Human molecular genetics, 2016, 05-15, Volume: 25, Issue:10

    Topics: Animals; Animals, Genetically Modified; Dopaminergic Neurons; Drosophila melanogaster; Glycogen Synthase Kinase 3 beta; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Lovastatin; Mice; Motor Neurons; Mutation; Nerve Degeneration; Neurites; Parkinson Disease; Parkinsonian Disorders; Proto-Oncogene Proteins c-akt; Serine Endopeptidases; Signal Transduction

2016
Impact of high cholesterol in a Parkinson's disease model: Prevention of lysosomal leakage versus stimulation of α-synuclein aggregation.
    European journal of cell biology, 2017, Volume: 96, Issue:2

    Topics: alpha-Synuclein; Anticholesteremic Agents; Cell Line, Tumor; Cell Survival; Cholesterol; Humans; Lovastatin; Lysosomes; Parkinson Disease; Reactive Oxygen Species

2017
Lovastatin ameliorates alpha-synuclein accumulation and oxidation in transgenic mouse models of alpha-synucleinopathies.
    Experimental neurology, 2010, Volume: 221, Issue:2

    Topics: alpha-Synuclein; Analysis of Variance; Animals; Brain; Cholesterol; Dendrites; Disease Models, Animal; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lewy Body Disease; Lovastatin; Mice; Mice, Transgenic; Microtubule-Associated Proteins; Neurons; Oxidation-Reduction; Parkinson Disease; Platelet-Derived Growth Factor; Thy-1 Antigens

2010
Simvastatin is associated with a reduced incidence of dementia and Parkinson's disease.
    BMC medicine, 2007, Jul-19, Volume: 5

    Topics: Age Factors; Aged; Aged, 80 and over; Atorvastatin; Databases as Topic; Dementia; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Lovastatin; Male; Parkinson Disease; Proportional Hazards Models; Pyrroles; Simvastatin; United States; Veterans

2007
Parkinsonism unmasked by lovastatin.
    Annals of neurology, 1995, Volume: 37, Issue:5

    Topics: Aged; Female; Humans; Lovastatin; Male; Middle Aged; Parkinson Disease

1995