Compounds > lovastatin

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lovastatin and Glioma

lovastatin has been researched along with Glioma in 18 studies

Research

Studies (18)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (16.67)	18.7374
1990's	10 (55.56)	18.2507
2000's	4 (22.22)	29.6817
2010's	1 (5.56)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Afshordel, S; Clasohm, J; Eckert, GP; Kern, B; Kögel, D; König, H; Priester, M; Weissenberger, J	1
Higashikubo, R; Jiang, Z; Lytle, RA; Rich, KM; Zheng, X	1
Baumann, M; Dörfler, A; Gabryś, D; Hessel, F; Krause, M; Oertel, R; Yaromina, A	1
Bhat, NR; Volpe, JJ	1
Jeng, I; Klemm, N; Proctor, B	1
Obert, KA; Volpe, JJ	1
Anker, L; Couldwell, WT; He, S; Hinton, DR; Jones, KD; Law, RE; Su, Y	1
Baetta, R; Butti, G; Davegna, C; De Renzis, MR; Fumagalli, R; Magrassi, L; Mazzini, G; Paoletti, R; Pezzotta, S; Soma, MR	1
Baetta, R; Battaini, F; Bergamaschi, S; Davegna, C; De Renzis, MR; Fumagalli, R; Govoni, S; Soma, MR	1
Liu, L; Prasanna, P; Samid, D; Thibault, A	1
Abe, T; Kikuchi, T; Nagata, Y	1
Andres, DA; Crick, DC; Danesi, R; Macchia, M; Waechter, CJ	1
Lin, SJ; Liu, HS; Wang, YS; Yang, BC	1
Dichgans, J; Groscurth, P; Kermer, M; Schmidt, F; Weller, M	1
Costa, E; Guarneri, P; Pan, B; Papadopoulos, V	1
Corsini, A; Paoletti, R; Soma, MR	1
Butti, G; Fumagalli, R; Pagliarini, P; Paoletti, P; Paoletti, R; Soma, MR	1
Bernier, L; Braun, PE; De Angelis, D; Shtybel, WW	1

Reviews

1 review(s) available for lovastatin and Glioma

Article	Year
Cholesterol and mevalonic acid modulation in cell metabolism and multiplication. Toxicology letters, 1992, Volume: 64-65 Spec No Topics: Animals; Cell Division; Cholesterol; Glioma; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mevalonic Acid; Muscles; Simvastatin	1992

Other Studies

17 other study(ies) available for lovastatin and Glioma

Article	Year
Lovastatin and perillyl alcohol inhibit glioma cell invasion, migration, and proliferation--impact of Ras-/Rho-prenylation. Pharmacological research, 2015, Volume: 91 Topics: Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cholesterol; Glioma; Humans; Lovastatin; Monoterpenes; Neoplasm Invasiveness; Prenylation; rac1 GTP-Binding Protein; ras Proteins; Terpenes	2015
Lovastatin-induced up-regulation of the BH3-only protein, Bim, and cell death in glioblastoma cells. Journal of neurochemistry, 2004, Volume: 89, Issue:1 Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Carrier Proteins; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Glioblastoma; Glioma; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; MAP Kinase Signaling System; Membrane Proteins; Polyisoprenyl Phosphates; Protein Prenylation; Protein Structure, Tertiary; Proto-Oncogene Proteins; Up-Regulation	2004
Effects of lovastatin alone or combined with irradiation on tumor cells in vitro and in vivo. Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2008, Volume: 184, Issue:1 Topics: Animals; Apoptosis; Brain Neoplasms; Carcinoma, Squamous Cell; Cell Cycle; Cell Division; Cell Line, Tumor; Combined Modality Therapy; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Glioma; Humans; Hypopharyngeal Neoplasms; In Vitro Techniques; Lovastatin; Mice; Mice, Nude; Neoplasm Transplantation; Radiation Dosage; Tumor Cells, Cultured; Tumor Stem Cell Assay	2008
Relation of cholesterol to astrocytic differentiation in C-6 glial cells. Journal of neurochemistry, 1984, Volume: 42, Issue:5 Topics: Animals; Anticholesteremic Agents; Astrocytes; Cell Differentiation; Cell Line; Cholesterol; Cycloheximide; Glioma; Glutamate-Ammonia Ligase; Kinetics; Lovastatin; Naphthalenes; Rats	1984
Insensitivity of ubiquinone biosynthesis in glioblastoma cells to an epileptogenic drug, U18666A. Journal of neurochemistry, 1984, Volume: 43, Issue:5 Topics: Androstenes; Animals; Anticholesteremic Agents; Cell Line; Glioma; Hydroxybenzoates; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Methionine; Mevalonic Acid; Naphthalenes; Parabens; Rats; Tyrosine; Ubiquinone	1984
Relation of cholesterol to oligodendroglial differentiation in C-6 glial cells. Journal of neurochemistry, 1983, Volume: 40, Issue:2 Topics: Animals; Anticholesteremic Agents; Cell Differentiation; Cell Line; Cholesterol; Clone Cells; Fatty Acids; Glioma; Kinetics; Lovastatin; Naphthalenes; Neuroglia; Oligodendroglia; Phospholipids; Rats; Sterols	1983
Lovastatin induces growth inhibition and apoptosis in human malignant glioma cells. Biochemical and biophysical research communications, 1994, Dec-30, Volume: 205, Issue:3 Topics: Apoptosis; Cell Division; DNA, Neoplasm; Dose-Response Relationship, Drug; Glioma; Humans; Lovastatin; Neoplasm Proteins; Protein Prenylation; Tumor Cells, Cultured	1994
In vivo enhanced antitumor activity of carmustine [N,N'-bis(2-chloroethyl)-N-nitrosourea] by simvastatin. Cancer research, 1995, Feb-01, Volume: 55, Issue:3 Topics: Animals; Astrocytoma; Carmustine; Cell Cycle; Cell Division; Cell Line; DNA, Neoplasm; Drug Synergism; Flow Cytometry; Glioma; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Mevalonic Acid; Rats; Rats, Sprague-Dawley; Simvastatin; Tumor Cells, Cultured	1995
PKC activity in rat C6 glioma cells: changes associated with cell cycle and simvastatin treatment. Biochemical and biophysical research communications, 1994, Apr-29, Volume: 200, Issue:2 Topics: Animals; Astrocytoma; Cell Cycle; Demecolcine; Glioma; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxyurea; Lovastatin; Mevalonic Acid; Protein Kinase C; Rats; Simvastatin; Tumor Cells, Cultured	1994
Lipid metabolism as a target for brain cancer therapy: synergistic activity of lovastatin and sodium phenylacetate against human glioma cells. Journal of neurochemistry, 1996, Volume: 66, Issue:2 Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Division; Drug Synergism; Glioma; Humans; Lipid Metabolism; Lovastatin; Mevalonic Acid; Neoplasm Invasiveness; Phenylacetates; Tumor Cells, Cultured; Ubiquinone	1996
In vitro and in vivo antiproliferative effects of simvastatin, an HMG-CoA reductase inhibitor, on human glioma cells. Journal of neuro-oncology, 1997, Volume: 34, Issue:3 Topics: Animals; Enzyme Inhibitors; Glioma; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Peroxidation; Lipoproteins, LDL; Lovastatin; Mice; Mice, Nude; Simvastatin; Tumor Cells, Cultured	1997
Geranylgeraniol overcomes the block of cell proliferation by lovastatin in C6 glioma cells. Journal of neurochemistry, 1998, Volume: 70, Issue:6 Topics: Animals; Cell Division; Diterpenes; Electrophoresis, Polyacrylamide Gel; Farnesol; Glioma; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mevalonic Acid; Molecular Weight; Nerve Tissue Proteins; Polyisoprenyl Phosphates; Protein Prenylation; Rats; Thymidine; Tumor Cells, Cultured	1998
Ras signaling is involved in the expression of Fas-L in glioma. Laboratory investigation; a journal of technical methods and pathology, 2000, Volume: 80, Issue:4 Topics: Antineoplastic Agents; Brain Neoplasms; Fas Ligand Protein; fas Receptor; Glioma; Humans; Lovastatin; Membrane Glycoproteins; Mutation; ras Proteins; Signal Transduction; Tumor Cells, Cultured	2000
Lovastatin and phenylacetate induce apoptosis, but not differentiation, in human malignant glioma cells. Acta neuropathologica, 2001, Volume: 101, Issue:3 Topics: Animals; Antineoplastic Agents; Apoptosis; Astrocytes; Brain Neoplasms; Cell Cycle; Cell Differentiation; Cell Survival; Dose-Response Relationship, Drug; Drug Interactions; Fas Ligand Protein; Gene Expression Regulation, Neoplastic; Glial Fibrillary Acidic Protein; Glioma; Humans; Lovastatin; Membrane Glycoproteins; Microscopy, Electron; Mutation; Phenylacetates; Proto-Oncogene Proteins c-bcl-2; Rats; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53	2001
Regulation of pregnenolone synthesis in C6-2B glioma cells by 4'-chlorodiazepam. Proceedings of the National Academy of Sciences of the United States of America, 1992, Jun-01, Volume: 89, Issue:11 Topics: Animals; Benzodiazepinones; Cholesterol; Diazepam Binding Inhibitor; Glioma; In Vitro Techniques; Lovastatin; Mitochondria; Neuropeptides; Pregnenolone; Rats; Receptors, Cell Surface; Time Factors; Tumor Cells, Cultured	1992
Simvastatin, an inhibitor of cholesterol biosynthesis, shows a synergistic effect with N,N'-bis(2-chloroethyl)-N-nitrosourea and beta-interferon on human glioma cells. Cancer research, 1992, Aug-15, Volume: 52, Issue:16 Topics: Anticholesteremic Agents; Carmustine; Cell Count; Cell Division; Culture Media; Dose-Response Relationship, Drug; Drug Synergism; Glioma; Humans; Hydroxymethylglutaryl CoA Reductases; Interferon-beta; Lovastatin; Simvastatin; Tumor Cells, Cultured	1992
Isoprenoid modification permits 2',3'-cyclic nucleotide 3'-phosphodiesterase to bind to membranes. Journal of neuroscience research, 1991, Volume: 30, Issue:3 Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Amino Acid Sequence; Animals; Cell Line; Cell Membrane; Cytosol; Glioma; Lovastatin; Mevalonic Acid; Molecular Sequence Data; Molecular Weight; Protein Binding; Protein Processing, Post-Translational	1991