Page last updated: 2024-08-23

lovastatin and Elevated Cholesterol

lovastatin has been researched along with Elevated Cholesterol in 685 studies

Research

Studies (685)

Timeframe	Studies, this research(%)	All Research%
pre-1990	73 (10.66)	18.7374
1990's	472 (68.91)	18.2507
2000's	98 (14.31)	29.6817
2010's	31 (4.53)	24.3611
2020's	11 (1.61)	2.80

Authors

Authors	Studies
Asanuma, K; Kaneko, R; Kobayashi, D; Tanabe, H; Tsuji, N; Watanabe, N	1
Rai, SK; Sharma, M; Tiwari, M	1
Heřmánková, E; Hobzová, R; Hromádka, R; Poláková, L; Širc, J; Žák, A	1
Antonic, T; Bogavac-Stanojevic, N; Gojkovic, T; Kotur-Stevuljevic, J; Spasojevic-Kalimanovska, V; Vekic, J; Vladimirov, S; Zeljkovic, A	1
Endo, A; Hattori, A; Hayashi, A; Ide, K; Ide, S; Inagaki, M; Ishikawa, T; Kitamoto, T; Kobayashi, J; Kobayashi, K; Koshizaka, M; Maezawa, Y; Minamizuka, T; Sakamoto, K; Shoji, M; Takemoto, M; Yamaga, M; Yokote, K	1
Benjian, C; Danping, XU; Huanlin, WU; Huiting, P; Xiaodan, H; Yishi, LI; Yongtao, C	1
Arnás, C; Corbella, E; de Dios, S; Florido, M; Licerán, M; Martin, D; Martinez-Martin, F; Petitbò, D; Pintó, X; Sánchez, A; Sánchez-Hernández, RM; Sarasa, I; Trias, F	1
Shi, Y; Yan, M; Zhang, G; Zhang, L	1
Antonicelli, R; Bonfigli, AR; Di Pillo, R; Galeazzi, R; Giuliani, A; Gurău, F; Matacchione, G; Montesanto, A; Olivieri, F; Protic, O; Sabbatinelli, J; Silvestrini, A	1
Ameneiros-Lago, E; Fernández-Fernández, FJ; Sardina-Ferreiro, R	1
Cicero, AFG; Fogacci, F; Stoian, AP; Toth, PP	1
Androulakis, I; Angelopoulos, N; Argyrakopoulou, G; Boniakos, A; Livadas, S; Paparodis, RD	1
Banach, M; Bruckert, E; Catapano, AL; Descamps, OS; Ellegård, L; Ezhov, M; Föger, B; Fras, Z; Kovanen, PT; Latkovskis, G; März, W; Panagiotakos, DB; Paragh, G; Pella, D; Pirillo, A; Poli, A; Reiner, Ž; Silbernagel, G; Viigimaa, M; Vrablík, M	1
Carbone, F; Cremonini, AL; Di Pierro, F; Favari, E; Formisano, E; Pasta, A; Pisciotta, L; Ronca, A; Semino, T; Sukkar, SG	1
Chen, X; Ji, X; Shang, J; Wei, Y; Xie, L; Zhang, C; Zhang, Q; Zhu, G	1
Hosseinpour, F; Rafieian-Kopaei, M; Shomali, T	1
Bonechi, C; Consumi, M; Donati, A; Lamponi, S; Leone, G; Magnani, A; Pepi, S; Rossi, C; Tamasi, G	1
Cicero, AFG	1
Airoldi, G; Ceccarini, G; Fierabracci, P; Jaccheri, R; Magno, S; Minale, M; Pelosini, C; Salvetti, G; Santini, F; Saponati, G; Vitti, J	1
Lenti, S; Mazza, A; Montanaro, F; Rigatelli, G; Schiavon, L; Torin, G	1
Di Giacomo, E; Lenti, S; Manunta, R; Mazza, A; Rubello, D; Schiavon, L; Tomasi, M; Torin, G; Townsend, DM	1
Bjune, K; Leren, TP; Naderi, S; Sundvold, H	1
Maghsoomi, Z; Moghadasi, M	1
Jan, MS; Lee, CY; Lin, CC; Shih, HC; Wei, JC; Yu, MC	1
Borghi, C; Cicero, AF; Grandi, E; Morbini, M; Parini, A; Reggi, A; Rosticci, M	1
Bukhari, SA; Javed, S; Meraj, M; Zovia, I	1
Davison, KM; Kaplan, BJ	1
Gerards, MC; Gerdes, VE; Koks, CH; Terlou, RJ; Yu, H	1
Barbagallo, C; Cicero, AF; Derosa, G; Pisciotta, L	1
Addabbo, F; Bonfrate, L; Carmosino, M; Castorani, L; Di Ciaula, A; Mastrofrancesco, L; Portincasa, P; Procino, G; Svelto, M	1
Averna, M; Blom, D; Cefalù, AB; Ciccarese, M; Cossu, M; Croyal, M; Dallinga-Thie, G; Guédon, A; Hovingh, K; Lambert, G; Passard, M; Peter, J; Pintus, P; Pisciotta, L; Prampart-Fauvet, S; Raal, F; Santos, RD; Sjouke, B; Thedrez, A	1
Bloks, VW; Brufau, G; de Boer, JF; Groen, AK; Kuivenhoven, JA; Mele, L; Schonewille, M; Tietge, UJ; Wolters, H; Wolters, JC	1
Hsu, YW; Lee, CL; Pan, TM; Wen, JY	1
Amento, EP; Bigos, M; Madasamy, S; Shivasubramani, U; Villanueva, J; Wu, AH	1
Dufresne, SS; Frenette, J; Piette, AB	1
Hadji, P; Hahn, A; Heinz, T; Möller, K; Schuchardt, JP	1
Avello L, M; Bravo D, M; Calvo M, C; Mennickent C, S	1
Glueck, CJ; Goldenberg, N; Khan, NA; Rawal, B; Wang, P; Yeramaneni, S	1
Hanson, M; Hoffman, R; Strony, J; Veltri, E	1
Abbasi, E; Nassiri-Asl, M; Zamansoltani, F; Ziaee, A	1
Chen, CW; Hsueh, CH; Hwang, JJ; Lai, LP; Shen, MJ; Su, YN; Tsai, CT	1
Jeon, TI; Osborne, TF; Seo, YK; Zhu, B	1
Fereshtehnejad, SM; Homayounfar, R; Kalani, A; Shidfar, F	1
Pokrovskiĭ, AV; Suntsov, DS	1
Croze, R; Levy, BD; Pfeffer, MA; Planagumà, A; Rubin, G; Serhan, CN; Uddin, M	1
Arranz Martínez, E; Gordillo López, FJ; Hermosa Hernán, JC; Ruiz García, A	1
Cunningham, E	1
Akhilender Naidu, K; Dhale, MA; Mohan-Kumari, HP; Vijayalakshmi, G	1
Wang, X; Yu, P	1
Arca, M; Budal, S; Degli Esposti, E; Degli Esposti, L; Sangiorgi, D; Vigna, GB	1
Cai, J; Cayo, MA; Clark, BS; Collery, RF; DeLaForest, A; Duncan, SA; Nagaoka, M; Noto, FK; Si-Tayeb, K	1
Chen, CH; Ding, YA; Tsao, HM; Yu, WC	1
McCarty, MF	1
Ahn, C; Aronow, WS	1
Chmielewski, M; Rutkowski, B; Zdrojewski, Z	1
Ferrières, J	1
Corbelli, J; Kerzner, B; LeBeaut, A; Lipka, LJ; Melani, L; Mukhopadhyay, P; Sharp, S; Suresh, R; Veltri, EP	1
Bouzamondo, A; Corvol, JC; Hulot, JS; Lechat, P; Sanchez, P; Sirol, M	1
McBurney, CR; Smith, DG	1
Curran, MP; Goa, KL	1
Amin, AH; Bafna, PA; Balaraman, R; Gulati, OD; Mehta, K	1
Osborne, TF; Shin, DJ	1
Davidson, MH; Dicklin, MR; Liss, C; Palmisano, J; Wilson, H	1
Plans-Rubió, P	2
Cullen, EI; Friedhoff, LT; Lukacsko, P; Niecestro, R; Walters, EJ	1
Edwards, JE; Moore, RA	1
Dunbar-Jacob, J; Muldoon, MF; Ryan, CM; Sereika, S; Stilley, CS	1
Tellier, P	1
Caramelli, B; Praça, JM; Thomaz, A	1
Corbelli, J; Crouse, JR; Insull, W; McGovern, ME; Schrott, H; Thompson, P; Zieve, F	1
Anga, B; Harangi, F; Schneider, I; Sebök, B; Tóth, M	1
Aguilar, P; Muñoz Díaz, AB	1
Diament, J; Forti, N	1
Endo, A; Sudo, H; Yammoto, A	1
Bennett, S; Lipka, L; Melani, L; Sager, P; Suresh, R; Veltri, E	1
Denke, MA	1
Klose, G	1
Battisti, WP; Brady, WE; Denke, MA; McBride, PE; Palmisano, J; Pearson, TA	1
Brousseau, ME; Kajinami, K; Ordovas, JM; Schaefer, EJ	1
Guharoy, R	1
Alende Sixto, MR; Martínez Rey, C; Rodríguez Framil, M; Torre Carballada, JA	1
Benson, V; Campen, D; Chan, J; Cheetham, TC; Levin, E; Richmond, C	1
Gibson, K; Rindone, JP	1
Antoniuk, MV; Gvozdenko, TA; Rudichenko, EV	1
Hamirani, YS; Jones, PH; Vasudevan, AR	1
Brown, BG; Brunzell, JD; Hokanson, JE; Motulsky, AG; Zambon, A	1
Balogh, Z; Fóris, G; Fülöp, P; Koncsos, P; Kosztáczky, B; Paragh, G; Seres, I	1
Griffin, KJ; Hsu, MH; Johnson, EF; Savas, U	1
Ghavamian, R; Goel, S; Stein, CA	1
Alsheikh-Ali, AA; Han, H; Karas, RH; Maddukuri, PV	1
Connelly, PW; de Souza, R; Emam, A; Faulkner, DA; Gigleux, I; Jenkins, DJ; Kendall, CW; Lamarche, B; Lapsley, KG; Marchie, A; Parker, TL; Trautwein, EA; Wong, JM	1
George, J; Keren, G; Luboshits, G; Mausner-Fainberg, K; Maysel-Auslender, S; Mor, A; Rubinstein, A	1
Agrawal, AR; Sharma, PL; Tandon, M	1
Blasetto, J; Gandhi, S; Harley, CR; Heien, H; Nelson, SP; Sasane, R	1
Traynor, K	1
Lee, T	1
Basak, GW; Bil, J; Bojarski, L; Dabrowska-Iwanicka, A; Engelberts, PJ; Gaciong, Z; Glodkowska, E; Golab, J; Gorska, E; Issat, T; Jakobisiak, M; Kurzaj, Z; Lasek, W; Lekka, M; Mackus, WJ; Makowski, M; Mrowka, P; Nowis, D; Parren, PW; Sinski, M; Stoklosa, T; Warzocha, K; Wasik, M; Wilczek, E; Wilczynski, GM; Winiarska, M	1
Brenner, H; Hahmann, H; Hoffmann, MM; Rothenbacher, D; Vossen, CY; Wüsten, B	1
Johnson, A	1
Brass, EP; Hwang, P; Levine, JG; Replogle, A; Rusche, S; Shiffman, S; Vassil, T	1
Fox, KM; Gandhi, SK; McKenney, JM; Ohsfeldt, RL	1
Alberts, AW; Chao, YS; Kroon, PA; Thompson, GM; Yamin, TT	1
Nakamura, N; Uzawa, H; Yamaguchi, K	1
Alberts, AW; Hand, KM; Huff, JW; Kroon, PA	1
Bosisio, E; Cighetti, G; Di Padova, C; Galli Kienle, M; Galli, G; Paoletti, R; Rovagnati, P	1
Fears, R; Ferres, H; Richards, DH	1
Endo, A; Sudo, H; Yamamoto, A	1
Oliver, MF	1
Ahmad, S	5
Iwasaki, T; Kato, S; Sasaki, H; Tada, N	1
Thompson, GR	1
Larsen, ML	1
Jacob, BG; Richter, WO; Schwandt, P	3
Smart, AJ; Walters, L	1
Forti, N	2
Altman, R; Bolzano, K; Davignon, J; DeWailly, P; Giannini, S; Jerums, G; Kastelein, JJ; Lansberg, PJ; Mitchel, YB; Shapiro, D	1
Branchi, A; Fiorenza, AM; Rovellini, A; Sommariva, D	1
Colquhoun, DM	1
Burns, K; Ellis, A; Haberl, E; Hook, N; Kellick, KA; McAndrew, E	1
Rubinstein, A; Weintraub, M	1
Adachi, Y; Kamisako, T	1
Block, G; Cutler, N; Lines, C; Sramek, J; Stauffer, L; Veroff, A	1
Brack, T; Krähenbühl, S; Maggiorini, M; Meier, C; Risti, B; Stey, C	1
Haffner, S; LaBelle, P; Orchard, T; Schmidt, D; Stein, E	1
Levenstein, S	1
Amano, M; Ino, T; Kasuga, M; Kazumi, T; Matsuba, K; Ohki, A; Yoshino, G	1
Bonal, J; Cantarell, C; Capdevila, L; Lauzurica, R; Pastor, C; Sierra, C	1
Agner, E; Agner, T; Malinowski, J; Meibom, J; Ramsing, D	1
Hershman, R; Iqbal, A; Robbins, MJ	1
Auerbach, BJ; Bisgaier, CL; Krause, BR; Newton, RS	1
Banks, D; Feher, MD; Foxton, J; Lant, AF; Wray, R	1
Beigel, Y; Fainaru, M; Gavish, D; Neuman, Y; Teplitzky, Y; Wurzel, M; Zafrir, N	1
Lefer, AM; Ma, XL	1
Jorge, PA; Metze, K; Ozaki, MR	1
Eizyk, E; Kalén, J; Katzman, P; Nilsson, A; Sartor, G; Ugander, L; Ursing, D	1
Hockwin, O; Paulus, U; Schmidt, J; Schmitt, C; von Bergmann, K	1
Arndtz, N; Meiser, B; Reichart, B; Seidel, D; Thiery, J; Wenke, K	1
Downey, P; Maiz, A; Martínez, L; Pinto, C; Retamal, F; Vaccarezza, A	1
Bär, PR; Contermans, J; Erkelens, DW; Smit, JW	1
Benson, VV; Borok, GM; Dudl, RJ; Epstein, A; Epstein, RS; Heys, JF; Menzin, J; Oster, G; Quinn, V	1
Applegate, WB; Curtis, RC; Davis, CE; Gordon, DJ; McCormick, M	1
Averna, M; Barbagallo, CM; Davì, G; Ganci, A; Giammarresi, C; La Placa, FP; Notarbartolo, A; Patrono, C	1
Curtis, RC; Dameworth, KS; Dowdy, AA; Hegland, J; Levin, JA; Sousoulas, BG; Stoy, DB	1
Ben Khalifa, F; Ftouhi, B; Kaabachi, A; Mebazaa, R; Mekaouer, A; Turki, S	1
Alaupovic, P; Dudley, VS; Knight-Gibson, C; Lane, DM; Laughlin, LO	1
Bertolami, MC; Diament, J; Faludi, AA; Forti, N; Giannini, SD; Schölz, J	1
Chamone, D; da Luz, P; Mansur, AP; Maranhão, R; Pileggi, F; Ramires, JA; Solimene, MC	1
Block, G; Cwudzinski, D; Gengo, F; Kinkel, P; Lines, C; Stauffer, L	1
Brandl, U; Detter, C; Kreuzer, E; Kur, F; Mair, H; Meiser, BM; Seidel, D; Thiery, J; Uberfuhr, P; Wenke, K	1
Arndtz, N; Meiser, B; Reichart, B; Seidel, D; Thiery, J; von Scheidt, W; Wenke, K	1
Davidson, MH; Dujovne, CA; Goris, GB; Oliphant, TH; Phillips, JC; Schrott, HG; Shawaryn, GG; Stein, EA	1
Himberg, JJ; Jokelainen, K; Laaksonen, R; Sahi, T; Tikkanen, MJ	1
Anderson, TJ; Frei, B; Ganz, P; Meredith, IT; Selwyn, AP; Yeung, AC	1
Kostis, JB; Rosen, RC; Wilson, AC	1
Denke, MA; Grundy, SM	1
Forfang, K; Geiran, O; Gullestad, L; Høstmark, AT; Ihlen, H; Nordal, KP; Simonsen, S	1
Clifton, PM; Nestel, PJ; Noakes, M	1
Chin, JP; Dart, AM	1
Huchzermeyer, H; Münzenmaier, R	1
Kulbertus, H; Legrand, V; Martinez, C	1
Arndtz, N; Reichart, B; Seidel, D; Thiery, J; Wenke, K	1
Beamish, RE; Dhalla, NS	1
Coupal, L; Grover, SA; Hamilton, VH; Racicot, FE; Zowall, H	1
Guimaraes, AC; Kettner, H; Lithell, H; Pitkänen, M; Sailer, D; Tuomilehto, J; Van Gaal, LF	1
Elliott, HL; Marshall, S; Meredith, PA	1
Panuccio, D; Romani, A; Trabatti, MR	1
Argenio, GF; Bernini, GP; Franchi, F; Gasperi, M; Salvetti, A; Vivaldi, MS	1
Campana, C; Gavazzi, A; Iacona, I; Perani, G; Regazzi, MB; Viganò, M	1
Bradford, RH; Chremos, AN; Dujovne, CA; Franklin, FA; Grillo, RB; Higgins, J; Langendorfer, A; Nash, DT; Pool, JL; Shear, CL	1
Black, HR; Christianson, DS; Davey, JA; Diotalevi, LJ; Isaacsohn, JL; Liskov, E; Nicholas, C; Setaro, JF; Stein, EA	1
Alonso-Pulpón, L; Anguita, M; Arizón, JM; Cavero, MA; Concha, M; Crespo, M; Pérez-Jiménez, F; Segovia, J; Vallés, F	1
Himberg, JJ; Laaksonen, R; Ojala, JP; Tikkanen, MJ	1
Csanády, M; Gógl, A; Jánosi, A; Karádi, I; Ofner, P; Romics, L; Tarján, J; Varga, L; Wórum, F; Zeltner, G	1
Adamska-Dyniewska, H; Chojnowska-Jezierska, J; Cybulska, B; Grzymisławski, M; Hryniewiecki, L; Kaliciński, A; Kawecka-Jaszcz, K; Kleinrok, A; Kokot, F; Kłos, ZJ	1
Service, RF	1
Kłosiewicz-Latoszek, L; Nowicka, G; Szostak, WB	1
Cummings, MH; Watts, GF	1
Alaupovic, P; Blankenhorn, DH; Cashin-Hemphill, L; Corder, CN; Hodis, HN; Knight-Gibson, C; Kramsch, DM; LaBree, L; Mack, WJ	1
Steinhagen-Thiessen, E	1
Arnadottir, M; Eriksson, LO; Germershausen, JI; Thysell, H	1
Gross, W; Grützmacher, P; März, W; Paul, D; Schoeppe, W; Siekmeier, R	1
Armitage, J; Collins, R; Fatemian, M; Kearney, E; Keech, A; Lawson, A; Lyon, V; MacMahon, S; Mindell, J; Wallendszus, K	1
De Luca, N; Del Mirto, C; Fontana, D; Gisonni, P; Iovino, G; Marchegiano, R; Pompeo, F; Trimarco, B	1
Hunninghake, DB; Probstfield, JL	1
Dujovne, CA; Frost, PH; Greguski, RA; Illingworth, DR; Knopp, RH; Mitchel, YB; Stein, EA; Tun, P; Zupkis, RV	1
Daenen, W; De Geest, H; Van Cleemput, J; Van Lierde, J; Vanhaecke, J	1
Miettinen, TA; Partinen, M; Pihl, S; Räikkönen, K; Strandberg, TE; Vanhanen, H	1
Keller, U; Miserez, AR; Rossi, FA	1
Devuyst, O; Goffin, E; Pirson, Y; van Ypersele de Strihou, C	1
Alberti, KG; Evans, K; Farrer, M; Kesteven, P; Laker, MF; Neil, HA; Winocour, PH	1
Benhamou, JP; Degott, C; Grimbert, S; Pessayre, D	1
Bos, FM; Duits, N	2
D'Agostino, LC; D'Agostino, RB; Kannel, WB; Stepanians, MN	2
Albers, JJ; Brown, BG; Dowdy, A; Fisher, LD; Hillger, LA; Sniderman, AD; Stewart, BF; Zhao, XQ	1
Goldstein, MR	1
Korman, LB	1
Hathaway, SC; Paat, JJ; Paterson, RW; Steele, GH; Wong, JG	1
Bonnefous, F; Debbas, N; Farnier, M; Irvine, A	1
Lambrecht, LJ; Malini, PL	1
Applegate, W; Crouse, JR; Davis, CE; Eckfeldt, JH; Gordon, DJ; Grimm, R; Hunninghake, DB; Knopp, R; LaRosa, JC	1
Dudko, VA; Kanskaia, NV; Konstantinov, VO; Kryzhanovskiĭ, VA; Kukharchuk, VV; Liakishev, AA; Lipovetskiĭ, BM; Soliternova, IB; Titov, VN; Volkova, EI	1
al-Jubouri, MA; Briston, PG; Chinn, RH; Sinclair, D; Young, RM	1
Alessandri, C; Andreozzi, P; Basili, S; Bracaglia, D; Cordova, C; Maurelli, M	1
Jacobs, MB	1
Farbstein, S	1
Block, G; Haigh, J; Miettinen, T; Murtomäki, E; Neafus, R; Partinen, M; Pihl, S; Reines, S; Strandberg, T; Vanhanen, H	1
Carbonieri, E; Cemin, C; Franceschini, L; Ghebremariam-Tesfau, K; Rossi, L; Tomei, R; Zardini, P	1
Akhmedzhanov, NM; Ivanova, TN; Metel'skaia, VA; Nikulina, SE; Olfer'ev, AM; Perova, NV; Poliakova, ED; Shcherbakova, IA	1
de Koning Gans, HJ; Gørbitz, C; Harrison, EM; Ose, L; Tonstad, S	1
Bratland, B; Dahlöf, B; Gisholt, K; Os, I; Syvertsen, JO; Tretli, S	1
Camarda, G	1
Bremer, J; Lintott, CJ; Scott, RS; Sutherland, WH	1
Alberti, KG; Klausen, IC; Mogensen, CE; Møller, N; Nielsen, S; Pørksen, N; Schmitz, O	1
Bedarida, GV; Blaschke, TF; Bushell, E; Haefeli, WE; Hoffman, BB	1
Baum, H; Castelluccio, C; Quinn, PJ; Rice-Evans, C; Taub, NA; Watts, GF	1
Heikkilä, JI; Kervinen, K; Kesäniemi, YA; Savolainen, MJ	1
Harris, KP; Hattersley, JM; Moorhead, JF; Ramaswamy, C; Thomas, ME; Varghese, Z; Walls, J; Wheeler, DC; Williams, JD	1
Peres, RB; Plavinik, F; Ribeiro, AB; Zampieri, M; Zanella, MT	1
Baines, MG; McPherson, R; Melino, MR; Pross, HF; Tsoukas, C; Vost, A; Zupkis, RV	1
Felgines, C; Lutton, C; Mathé, D; Mazur, A; Sérougne, C	1
Aviram, M; Brook, JG; Cogan, U; Hochgraf, E; Levy, Y	1
Arca, M; Grundy, SM; Vega, GL	1
Chylack, LT; Friend, J; Mantell, G; Rosner, B; Wolfe, JK	1
De Haan, AF; Kastelein, JJ; Kortmann, B; Kroon, AA; Lansberg, PJ; Stalenhoef, AF; Stuyt, PM	1
Bondarenko, BB; Gurevich, VS; Kasennova, NI; Le Van Thach, TD; Mikhailova, IA	1
Heudebert, GR; Hiatt, J; Schectman, G; Van Ruiswyk, J	1
Cheung, AK; DeVault, GA; Gregory, MC	1
McDonagh, J; Walker, DJ; Winocour, P	1
Blank, D; Brun, LD; Campeau, L; Crockford, P; Curnew, G; Dafoe, W; Davignon, J; Dufour, R; Emery, G; Frohlich, J	1
Chiu, K; Lai, KN; Lam, CW; Leung, CB; Li, PK; Lui, SF; Mak, GY; Mak, TW	1
Holdcroft, C	1
Bjornsson, TD; Conroy, JA; Fruncillo, RJ; Holland, SD; McCrea, JB; Shingo, S; Spector, R	1
Brown, SE; Ornish, D	1
Golay, A; James, R; Lehmann, T; Pometta, D	1
Baigts, F; Devulder, B; Lecerf, JM; Luc, G	1
Lai, KN; Lam, CW; Li, PK; Mak, TW	1
Blankfield, RP	1
Mattila, SP; Tikkanen, MJ; Tilly-Kiesi, M	1
Alsina, J; Andrés, E; Castelao, AM; Castiñeiras, MJ; Galcerán, JM; Gilvernet, S; González, MT; Griñó, JM; Roca, M; Serón, D	1
Hartz, A; Hiatt, J; Schectman, G	1
Simons, LA	1
Tobert, JA	4
Alemanno, N; Cassader, M; Gambino, R; Pagano, G; Ruiu, G; Veglia, F	1
Caputo, S; Ghirlanda, G; Greco, AV; Lippa, S; Littarru, GP; Manto, A; Oradei, A; Uccioli, L	1
Dujovne, CA; Feldman, EB; Harris, WS; Held, J; Hunninghake, DB; Laskarzewski, PM; Miller, VT; Quiter, E; Stein, EA; Tobert, JA	1
Block, GA; Eckernäs, SA; Eriksson, LO; Haigh, JR; Kvidal, P; Neafus, RP; Roos, BE	1
Bradford, RH; Chremos, AN; Downton, M; Langendörfer, A; Mantell, G; Nash, DT; Shear, CL; Stinnett, S	1
Falaschi, F; Finardi, G; Franco, C; Perani, G; Ricciardi, R; Tramarin, R	1
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McIsaac, W; Naylor, D	1
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Hennekens, CH	1
Malminiemi, K; Malminiemi, O; Palomäki, A; Solakivi, T	1
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Hunninghake, DB	3
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Oster, G; Thompson, D	1
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Bakker-Arkema, RG; Black, DM; Nawrocki, JW	1
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Cromwell, WC; Ziajka, PE	1
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Bays, H; Cuffie-Jackson, C; Davidson, MH; Dujovne, CA; Goldberg, AC; Hunninghake, DB; Jones, P; Knopp, R; Lipka, LJ; Stein, EA	1
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Golomb, BA; Jaworski, B	1
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Gagnon, RF; Stewart-Phillips, JL; Subang, MC	1
Pekkanen, J; Smith, GD	1
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Parfitt, A; Simons, J; Simons, LA	1
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Barnett, MD; McKenney, JM; Proctor, JP; Wright, JT	1
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Mueller, BA; Wallace, CS	1
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Clifton, PM; Nestel, PJ; Wight, MB	1
Ebeling, T; Pyörälä, K; Reijonen, T; Turtola, H; Uusitupa, M; Voutilainen, E	1
Tamburrini, LR	1
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Antosiewicz, J; Mazzanti, L; Polenta, M; Rabini, RA; Staffolani, R; Testa, I	1
Kostis, JB; Wilson, AC	1
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Bruckert, E; De Gennes, JL; Truffert, J	1
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Bradford, RH; Chremos, AN; Downton, M; Dujovne, CA; Franklin, FA; Higgins, J; Nash, DT; Pool, JL; Schnaper, H; Shear, CL	1
Cigala, O; Della Valle, M; Malarbi, AL; Marasco, A; Pancallo, MT	1
Horcicka, V; Jezdinský, J; Pudilová, L; Skottová, N; Trtková, M; Vaverková, H	1
Brocard, JJ; Keller, U; Oberhänsli, A; Riesen, WF	1
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Bradford, RH; Chremos, AN; Dujovne, CA; Franklin, FA; Hesney, M; Hurley, DP; Nash, DT; Pool, JL; Schnaper, H; Shear, CL	1
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Beigel, Y; Djaldetti, M; Fuchs, J; Green, P; Lurie, Y; Snir, M	1
Goldman, L; Goldman, PA; Weinstein, MC; Williams, LW	1
Gotto, AM; Hay, JW; Wittels, EH	1
Collins, P; Johnson, A; Owens, D; Robinson, K; Tighe, O; Tomkin, GH	1
Kuijpens, JL; Martens, LL; Rutten, FF; Winter, J	1
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Charleson, H; French, JK; Lewis, GR; Lintott, CJ; Maling, TJ; Nye, ER; Reuben, S; Scott, RS; Sharpe, DN; White, HD	1
Yeatman, E	1
Aalto-Setälä, K; Ehnholm, C; Helve, E; Kontula, KK; Ojala, JP; Tikkanen, MJ	1
Bednarek, M; Broda, G; Chotkowska, E; Kuzmińska, A; Polakowska, M; Rywik, S	1
Ewing, SL; Gebhard, RL; Hunninghake, DB; Prigge, WF; Schlasner, LA	1
Groskop, I; Lurie, Y; Rubinstein, A; Weintrob, M	1
Bocanegra, TS; Boccuzzi, SJ; Keegan, ME; Shapiro, DR; Walker, JF	1
Agheli, N; Jacotot, B	1
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Tikkanen, MJ; Tilly-Kiesi, M	1
Bo, M; Fabris, F; Fiandra, U; Pedrazzini, V; Pernigotti, L; Poli, L; Zanocchi, M	1
Firth, JC; Fourie, J; Kotze, TJ; Marais, AD; Omar, MA; Stander, I; Steyn, K; Van Gelder, AL; Vermaak, WJ; Weich, HF	1
Hörl, WH; Luley, CH; Wanner, C; Wieland, H	1
Archibald, MP; McDowell, IF; Nicholls, DP; Shortt, JA; Smye, M; Trimble, ER; Trinick, T	1
Barcina, C; Cuesta, L; Fernández, E; Lázaro-Carrasco, E; Navarro, A; Rivera, G; Rodríguez Padial, L; Sánchez Domínguez, J	1
Alberts, AW; Beil, FU; Beisiegel, U; Eckardt, HG; Greten, H; Karkas, JD; Liou, R; Schrameyer-Wernecke, A; Till, AE	1
Drouin, P; Ziegler, O	1
Amadio, L; Antonicelli, R; Lipponi, G; Paciaroni, E	1
Lundh, BL; Nilsson, SE	1
Goa, KL; Todd, PA	1
Hockwin, O; Schmidt, J; Schmitt, C	1
Grundy, SM; Krauss, RM; Vega, GL	1
Goryance, JM; Heim-Duthoy, KL; Kasiske, BL; Rao, KV; Tortorice, KL	1
Cohn, PF	1
Ishida, F; Kakubari, K; Kamei, T; Kitani, K; Sato, A; Taguchi, K; Watanabe, K	1
Aronson, JK; Ng, LL	1
Maher, VM; Thompson, GR	1
Eisenberg, JM; Glick, H; Jacobson, TA; Kinosian, B; Koffer, H; Schulman, KA; Willian, MK	1
Kreisberg, RA	1
Caridis, R; Catalano, A; Gavelli, MS; Guarini, G; Rossi, FG; Santini, G; Serra, T; Tozzi, J; Vitaliano, E	1
Caridis, R; Gavelli, MS; Rizzuti, A; Rossi, FG; Serra, T; Tozzi, J; Vitaliano, E	1
Dachet, C; De Gennes, JL; Douste-Blazy, P; Drouin, P; Fricker, J; Keller, U	1
Shapiro, DR; Walker, JF	1
Thompson, WG	1
Thiery, J	1
Jankelow, D; Myburgh, DP; Neutel, JM; Smith, DH	1
Clifton, P; Cooper, ME; Jennings, GL; Jerums, G; Nestel, PJ; O'Brien, RC; Simons, LA; Sullivan, D	1
D'Agostino, LC; D'Agostino, RB; Kannel, WB; Stepanians, M	1
Goldberg, R; La Belle, P; Ronca, P; Zupkis, R	1
Bradford, RH; Chremos, AN; Dujovne, C; Franklin, FA; Hesney, M; Higgins, J; Langendörfer, A; Pool, JL; Schnaper, H; Shear, CL	1
Creutzfeldt, C; Creutzfeldt, W; Seidel, D; Thiery, J; Walli, AK	1
Barth, JD; Kruisbrink, OA; Van Dijk, AL	1
Brownfield, E; Chuck, C; Kamjoo, P; Kawata, N; Kobashigawa, JA; Leonard, L; Moriguchi, JD; Murphy, FL; Stevenson, LW; Wilmarth, J	1
Allan, J; Johnson, BF; LaBelle, P; Ronca, PD; Wilson, J; Zupkis, RV	1
Grundy, SM; Vega, GL	3
Dollerup, J; Leth, A; Munch, M; Nielsen, B	1
Bentivoglio, M; Berioli, S; Conti, R; Corea, L; Osanna, RA; Savino, K; Zollino, L	1
Degenaar, CP; Nieuwenhuijzen Kruseman, AC; van Deursen, RT; Wolffenbuttel, BH	1
Folkers, K; Langsjoen, P; Richardson, P; Tamagawa, H; Willis, R; Xia, LJ; Ye, CQ	1
Barlow, CW; Friedman, BM; Myburgh, DP; Smith, DH; Soicher, ER; Steenkamp, WF	1
Abouganem, D; Núñez, P	1
Kohn, IJ; Ribeiro, L	1
de Góes, JM; Dereviack, BE; Diament, J; Forti, N; Giannini, SD; Machado, C	1
Brusco, OJ	1
Harris, KP; Klahr, S; Purkerson, ML; Yates, J	1
Nye, ER	1
French, JK; Greaves, SC; White, HD	1
Anderson, A; Hopper, J; Macaskill, G; McDonald, P; Morgan, T	1
Carlsson, M; Mölgaard, J; Nilsson, J; Olsson, AG	1
Gross, TP; Pierce, LR; Wysowski, DK	1
Helve, E; Karjalainen, K; Ojala, JP; Tarkkanen, A; Tikkanen, MJ	1
Armstrong, V; Bosch, T; Eisenhauer, T; Schuff-Werner, P; Seidel, D; Thiery, J	1
Adams, M; Dell, RB; Goldberg, IJ; Goodman, DS; Holleran, S; Palmer, RH; Ramakrishnan, R	1
Bagdade, JD; Lane, JT; Ritter, MC; Stone, N; Subbaiah, PV	1
Bach, LA; Cooper, ME; Jerums, G; O'Brien, RC	1
Kreisberg, R; Mantell, G; Miller, V; Shapiro, DR; Stein, E; Washington, L	1
Baker, SG; Berger, GM; Joffe, BI; Marais, AD; Mendelsohn, D; Seftel, HC; Welsh, NH	1
Behrens-Baumann, W; Creutzfeldt, C; Morawietz, A; Seidel, D; Thiery, J	1
Mölgaard, J; Olsson, AG; von Schenck, H	2
Keller, U; Riesen, WF; Stohler, R	1
Breslow, JL; Eisenberg, S; Weintraub, MS	1
Bankhurst, AD; Cutts, JL	1
Bolzano, K; Breslow, JL; Gavish, D; Kostner, GM; Leopold, B; Weintraub, MS	1
Demacker, PN; Hermus, AR; Mol, MJ; Stalenhoef, AF; Stuyt, PM; Van 'T Laar, A	1
Arnon, R; Eisenberg, S; Israeli, A; Raveh, D; Stein, Y	1
Ashy, A; Jürgens, G; Zenker, G	1
Frerman, FE; Greene, C; Walravens, PA	1
Illingworth, DR; Maher, VM; Pappu, A; Thompson, GR	1
Stoy, DB	1
Frishman, WH; Rapier, RC	1
Alexander, S; Cook, TJ; Mantell, G; Pietro, DA; Staggers, JE	1
Bennett, WM; Golper, TA; Illingworth, DR; Morris, CD	1
DiSesa, VJ; Gordon, J; Kirshenbaum, JM; Kuo, PC; Laffel, G; Mudge, GH; Vaughan, DE; Young, P	1
Lintott, CJ; Nye, ER; Robertson, MC; Scott, RS; Sutherland, WH	1
Nordøy, A; Ytre-Arne, K	1
Deslypere, JP	1
Carré, JM; Garcia, RC; Nakandakare, ER; Oliveira, HC; Quintão, EC; Zerbinatti, CV	1
Bard, JM; Dachet, C; De Gennes, JL; Douste-Blazy, P; Drouin, P; Fruchart, JC; Jacotot, B; Luc, G; Ziegler, O	1
Ammann, F; Baur, HR; Bertel, O; Del Bufalo, A; Golay, A; Keller, U; Kistler, H; Kummer, H; Reutter, FW; Riesen, WF	1
Brusca, A; Caruzzo, C; Caruzzo, E; Marcolongo, M; Uslenghi, E; Varbella, F	1
Ishida, F; Kamei, T; Kobayashi, M; Ohmura, I; Taguchi, K; Takahashi, T; Watanabe, K	1
Dammann, HG; Dreyer, M; Grüneberger, S; Kangah, R; Müller, P; Reinicke, A; Simon, B; Staisch, C; Steinhagen-Thiessen, E	1
Bojanovski, D; Bojanovski, M; Canzler, H; Jochim, A; Schulzeck, P	1
Fusman, B; Lefer, AM; Lento, PH; Osborne, JA; Siegfried, MR; Stahl, GL	1
Mol, MJ; Stalenhoef, AF; Stuyt, PM	1
Costa, C; Guarini, G; Santese, D; Trimarco, C; Vitaliano, E	1
Bard, JM; Devulder, B; Douste-Blazy, P; Fruchart, JC; Harvengt, C; Lecerf, JM; Leclerc, V	1
Alberts, AW	1
Helve, E; Jäättelä, A; Kaarsalo, E; Lehtonen, A; Malbecq, W; Oksa, H; Pääkkönen, P; Salmi, J; Tikkanen, MJ; Veharanta, T	1
Garg, A; Grundy, SM	1
Helve, E; Tikkanen, MJ	1
Buchwald, H; Campos, CT; Dombrovskis, S; Esper, E; Matts, JP; Tijerina, O	1
Schechter, RJ	1
Corpier, CL; Jones, PH; Lederer, ED; Quinones, MA; Schmidt, SW; Suki, WN; Young, JB	1
Ballantyne, CM; DeBakey, ME; Gotto, AM; Jones, PH; Noon, GP; Patsch, W; Payton-Ross, C; Short, HD; Young, JB	1
Tobert, JA; Walker, JF	1
Brewer, HB; Hoeg, JM	1
Blake, GJ	1
Fraunfelder, FT	1
Bewley, DZ; Lamkin, GE; Stein, EA	1
Olive, KE	1
Duane, WC; Freeman, ML; Gebhard, RL; Hunninghake, DB; Prigge, WF	1
Nikkilä, EA; Tikkanen, MJ	1
Bailey, KR; Brewer, HB; Hoeg, JM; Maher, MB	1
Escobar, A; Joven, J; Masana, L; Rubiés-Prat, J	1
DiPalma, JR	1
Santafé Oroz, J; Segarra Domènech, J	1

Reviews

71 review(s) available for lovastatin and Elevated Cholesterol

Article	Year
Polymeric bile acid sequestrants: Review of design, in vitro binding activities, and hypocholesterolemic effects. European journal of medicinal chemistry, 2018, Jan-20, Volume: 144 Topics: Animals; Anticholesteremic Agents; Bile Acids and Salts; Binding Sites; Drug Design; Humans; Hypercholesterolemia; Molecular Structure; Polymers	2018
Red Yeast Rice for the Improvement of Lipid Profiles in Mild-to-Moderate Hypercholesterolemia: A Narrative Review. Nutrients, 2023, May-12, Volume: 15, Issue:10 Topics: Anticholesteremic Agents; Atherosclerosis; Biological Products; Cholesterol; Cholesterol, LDL; Dietary Supplements; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipidemias; Lovastatin	2023
The role of red yeast rice (RYR) supplementation in plasma cholesterol control: A review and expert opinion. Atherosclerosis. Supplements, 2019, Volume: 39 Topics: Biological Products; Biotransformation; Cardiovascular Diseases; Cholesterol; Clinical Trials as Topic; Cytochrome P-450 CYP3A; Dietary Supplements; Double-Blind Method; Expert Testimony; Food-Drug Interactions; Gastrointestinal Diseases; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Medicine, Chinese Traditional; Molecular Structure; Multicenter Studies as Topic; Musculoskeletal Diseases; Prodrugs; Randomized Controlled Trials as Topic; Self Medication	2019
An overview on the biological activity and anti-cancer mechanism of lovastatin. Cellular signalling, 2021, Volume: 87 Topics: Apoptosis; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Neoplasms	2021
Traditional Chinese lipid-lowering agent red yeast rice results in significant LDL reduction but safety is uncertain - a systematic review and meta-analysis. Atherosclerosis, 2015, Volume: 240, Issue:2 Topics: Anticholesteremic Agents; Biological Products; Biomarkers; Chi-Square Distribution; Cholesterol, LDL; Dietary Supplements; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Medicine, Chinese Traditional; Odds Ratio; Risk Assessment; Risk Factors; Treatment Outcome	2015
[Pleiotropic effects of statins]. Revista medica de Chile, 2008, Volume: 136, Issue:6 Topics: Anticholesteremic Agents; Antioxidants; Atherosclerosis; Atorvastatin; Endothelium, Vascular; Fatty Acids, Monounsaturated; Fluorobenzenes; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Oxidative Stress; Pravastatin; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Sulfonamides	2008
[Statins in practice of the vascular surgeon and cardiologist]. Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery, 2009, Volume: 15, Issue:2 Topics: Aged; Anticholesteremic Agents; Cardiovascular Diseases; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Lovastatin; Male; Meta-Analysis as Topic; Myocardial Infarction; Myocardial Ischemia; Randomized Controlled Trials as Topic; Risk Factors; Time Factors	2009
Benefits and menaces related to the use of statins in patients after renal transplantation. Annals of transplantation, 2002, Volume: 7, Issue:2 Topics: Atorvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Kidney Transplantation; Lovastatin; Postoperative Complications; Pravastatin; Pyrroles; Simvastatin	2002
[Primary and secondary prevention of coronary disease by statins]. Annales de cardiologie et d'angeiologie, 1999, Volume: 48, Issue:2 Topics: Anticholesteremic Agents; Cholesterol, LDL; Coronary Angiography; Coronary Disease; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Pravastatin; Primary Prevention; Randomized Controlled Trials as Topic; Research Design; Risk Factors; Simvastatin; Survival Analysis; Survival Rate; Treatment Outcome	1999
Differential effects of lipid-lowering therapies on stroke prevention: a meta-analysis of randomized trials. Archives of internal medicine, 2003, Mar-24, Volume: 163, Issue:6 Topics: Anticholesteremic Agents; Atorvastatin; Cholestyramine Resin; Clofibrate; Colestipol; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Myocardial Infarction; Pravastatin; Pyrroles; Randomized Controlled Trials as Topic; Regression Analysis; Risk Assessment; Risk Factors; Simvastatin; Stroke; Treatment Failure; Treatment Outcome	2003
Lovastatin extended release: a review of its use in the management of hypercholesterolaemia. Drugs, 2003, Volume: 63, Issue:7 Topics: Absorption; Administration, Oral; Anticholesteremic Agents; Coronary Disease; Delayed-Action Preparations; Dose-Response Relationship, Drug; Humans; Hypercholesterolemia; Lovastatin	2003
Statins in hypercholesterolaemia: a dose-specific meta-analysis of lipid changes in randomised, double blind trials. BMC family practice, 2003, Dec-01, Volume: 4 Topics: Atorvastatin; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Female; Fluorobenzenes; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Male; Pravastatin; Pyridines; Pyrimidines; Pyrroles; Randomized Controlled Trials as Topic; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Triglycerides	2003
[Ezetimibe: from pharmacology to clinical trials]. Annales d'endocrinologie, 2003, Volume: 64, Issue:6 Topics: Animals; Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol, LDL; Clinical Trials as Topic; Coronary Disease; Depression, Chemical; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Heptanoic Acids; Hypercholesterolemia; Intestinal Absorption; Liver; Lovastatin; Pravastatin; Pyrroles; Safety; Simvastatin; Treatment Outcome	2003
[Vastatins in atherosclerosis prevention. Current data]. Arquivos brasileiros de cardiologia, 2004, Volume: 83, Issue:3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Arteriosclerosis; Epidemiologic Methods; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged	2004
Safety of statins: effects on muscle and the liver. Cleveland Clinic journal of medicine, 2005, Volume: 72, Issue:11 Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; C-Reactive Protein; Chemical and Drug Induced Liver Injury; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Liver; Liver Diseases; Lovastatin; Muscle, Skeletal; Rhabdomyolysis	2005
Effect of the magnitude of lipid lowering on risk of elevated liver enzymes, rhabdomyolysis, and cancer: insights from large randomized statin trials. Journal of the American College of Cardiology, 2007, Jul-31, Volume: 50, Issue:5 Topics: Chemical and Drug Induced Liver Injury; Cholesterol, LDL; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Liver Diseases; Lovastatin; Neoplasms; Pravastatin; Rhabdomyolysis; Simvastatin	2007
Recommendations for treatment of hyperlipidemia in adults. A joint statement of the Nutrition Committee and the Council on Arteriosclerosis. Circulation, 1984, Volume: 69, Issue:5 Topics: Cholesterol; Clofibrate; Coronary Disease; Female; Gemfibrozil; Humans; Hypercholesterolemia; Hyperlipidemias; Hyperlipoproteinemia Type IV; Hyperlipoproteinemias; Lactation; Lipoproteins; Lovastatin; Naphthalenes; Niacin; Pentanoic Acids; Pregnancy; Pregnancy Complications; Probucol; Tangier Disease; Triglycerides	1984
Angiographic trials of lipid-lowering therapy: end of an era? British heart journal, 1995, Volume: 74, Issue:4 Topics: Adult; Clinical Trials as Topic; Coronary Angiography; Coronary Disease; Female; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lipids; Lovastatin; Male; Middle Aged; Simvastatin	1995
Impact of intensive lipid modulation on angiographically defined coronary disease: clinical implications. Southern medical journal, 1994, Volume: 87, Issue:2 Topics: Angiography; Clinical Trials as Topic; Colestipol; Coronary Disease; Humans; Hypercholesterolemia; Lipids; Lovastatin; Niacin; Random Allocation	1994
[Psychiatric disorders with use of simvastatin]. Nederlands tijdschrift voor geneeskunde, 1993, Jun-26, Volume: 137, Issue:26 Topics: Adult; Anticholesteremic Agents; Anxiety Disorders; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Middle Aged; Psychoses, Substance-Induced; Simvastatin	1993
Statin therapy in clinical practice: new developments. Current opinion in lipidology, 1995, Volume: 6, Issue:5 Topics: Angina Pectoris; Anticholesteremic Agents; Cholesterol; Enzyme Inhibitors; Female; Heart Diseases; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Middle Aged; Myocardial Infarction; Simvastatin	1995
The 4S study. Implications for prescribing. Drugs, 1996, Volume: 51, Issue:4 Topics: Anticholesteremic Agents; Cholesterol; Controlled Clinical Trials as Topic; Coronary Disease; Cost-Benefit Analysis; Diet; Guidelines as Topic; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Life Style; Longitudinal Studies; Lovastatin; Simvastatin	1996
Benefits and risks of HMG-CoA reductase inhibitors in the prevention of coronary heart disease: a reappraisal. Drug safety, 1996, Volume: 14, Issue:1 Topics: Clinical Trials as Topic; Coronary Disease; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Pravastatin; Simvastatin	1996
Hyperlipidaemia and cardiovascular disease. Current opinion in lipidology, 1996, Volume: 7, Issue:3 Topics: Anticholesteremic Agents; Coronary Disease; Humans; Hypercholesterolemia; Lovastatin; Pravastatin	1996
The new paradigm for coronary artery disease: altering risk factors, atherosclerotic plaques, and clinical prognosis. Mayo Clinic proceedings, 1996, Volume: 71, Issue:10 Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anticholesteremic Agents; Antioxidants; Coronary Angiography; Coronary Artery Disease; Endothelium, Vascular; Exercise Test; Humans; Hypercholesterolemia; Inflammation; Lovastatin; Platelet Aggregation Inhibitors; Prognosis; Randomized Controlled Trials as Topic; Risk Factors; Simvastatin	1996
Pharmacodynamics and pharmacokinetics of the HMG-CoA reductase inhibitors. Similarities and differences. Clinical pharmacokinetics, 1997, Volume: 32, Issue:5 Topics: Anticholesteremic Agents; Arteriosclerosis; Brain; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Fluvastatin; Food-Drug Interactions; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Liver; Lovastatin; Pravastatin; Simvastatin	1997
Cholesterol management in patients with heart disease. Emphasizing secondary prevention to increase longevity. Postgraduate medicine, 1997, Volume: 102, Issue:2 Topics: Anticholesteremic Agents; Coronary Disease; Humans; Hypercholesterolemia; Longevity; Lovastatin; Niacin; Simvastatin	1997
[Prevention and therapy of vascular damage and endothelial dysfunction with hypocholesteremic agents]. Giornale italiano di cardiologia, 1998, Volume: 28, Issue:2 Topics: Anticholesteremic Agents; Arteriosclerosis; Cholesterol; Cholesterol, LDL; Clinical Trials as Topic; Coronary Disease; Diet; Endothelium, Vascular; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Lovastatin; Male; Mevalonic Acid; Middle Aged; Physical Exertion; Primary Prevention; Simvastatin; Time Factors	1998
Prevention. Who should take cholesterol-lowering drugs? Harvard health letter, 1998, Volume: 23, Issue:3 Topics: Aged; Anticholesteremic Agents; Cholesterol, HDL; Cholesterol, LDL; Estrogen Replacement Therapy; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Myocardial Ischemia; Pravastatin	1998
[Are there differences in various statins?]. Der Internist, 1998, Volume: 39, Issue:9 Topics: Anticholesteremic Agents; Cholesterol; Coronary Disease; Humans; Hypercholesterolemia; Lovastatin; Pravastatin; Simvastatin; Treatment Outcome; Triglycerides	1998
Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in transplant patients: are the statins mechanistically similar? Pharmacology & therapeutics, 1998, Volume: 80, Issue:1 Topics: Drug Interactions; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipidemias; Immunosuppressive Agents; Lovastatin; Naphthalenes; Organ Transplantation	1998
[Statins (HMG-CoA reductase inhibitors), cholesterol and stroke]. Revista de neurologia, 1998, Volume: 27, Issue:159 Topics: Adult; Arteriosclerosis; Cerebrovascular Disorders; Cholesterol; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Ischemic Attack, Transient; Lipoproteins, HDL; Lipoproteins, LDL; Lovastatin; Male; Middle Aged; Pravastatin; Risk Factors; Simvastatin; Triglycerides	1998
Is aggressive cholesterol control justified? Review of the post-coronary artery bypass graft trial. The American journal of cardiology, 1998, Nov-26, Volume: 82, Issue:10B Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol, LDL; Coronary Artery Bypass; Coronary Disease; Dose-Response Relationship, Drug; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Postoperative Period; Randomized Controlled Trials as Topic; Treatment Outcome	1998
Simvastatin: a pharmacoeconomic evaluation of its cost-effectiveness in hypercholesterolaemia and prevention of coronary heart disease. PharmacoEconomics, 1992, Volume: 1, Issue:2 Topics: Adult; Aged; Coronary Disease; Costs and Cost Analysis; Drug Prescriptions; Drug Tolerance; Economics, Pharmaceutical; Female; Formularies as Topic; Humans; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Primary Prevention; Risk Factors	1992
Cost-effectiveness of drug therapy for hypercholesterolaemia: a review of the literature. PharmacoEconomics, 1992, Volume: 2, Issue:1 Topics: Age Factors; Cholestyramine Resin; Colestipol; Coronary Disease; Cost-Benefit Analysis; Humans; Hypercholesterolemia; Lovastatin; Risk Factors; Sex Factors; Treatment Outcome	1992
[Clinical studies on hyperlipidemia]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1999, Sep-10, Volume: 88, Issue:9 Topics: Acyl Coenzyme A; Anticholesteremic Agents; Blood Component Removal; Clinical Trials as Topic; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lovastatin	1999
Statins and cerebrovascular disease: plaque attack to prevent brain attack. Vascular medicine (London, England), 1999, Volume: 4, Issue:4 Topics: Adult; Aged; Anticholesteremic Agents; Blood Vessels; Clinical Trials as Topic; Humans; Hypercholesterolemia; Lovastatin; Middle Aged; Pravastatin; Stroke	1999
Safety profile of atorvastatin-treated patients with low LDL-cholesterol levels. Atherosclerosis, 2000, Volume: 149, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Atorvastatin; Dose-Response Relationship, Drug; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Lipoproteins, LDL; Lovastatin; Male; Middle Aged; Pravastatin; Pyrroles; Randomized Controlled Trials as Topic; Severity of Illness Index; Simvastatin; Treatment Outcome	2000
[Additional effects of statins independent of the cholesterol-lowering as yet not shown to be clinically relevant]. Nederlands tijdschrift voor geneeskunde, 2000, Feb-12, Volume: 144, Issue:7 Topics: Anticholesteremic Agents; Arteriosclerosis; Clinical Trials as Topic; Confounding Factors, Epidemiologic; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Pravastatin; Simvastatin	2000
Bridging the treatment gap. The American journal of cardiology, 2000, Jun-22, Volume: 85, Issue:12A Topics: Adult; Anticholesteremic Agents; Cardiovascular Diseases; Coronary Disease; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Pravastatin; Risk Factors; Self Medication; Simvastatin; United States	2000
"The lower the better" in hypercholesterolemia therapy: a reliable clinical guideline?. Annals of internal medicine, 2000, Oct-03, Volume: 133, Issue:7 Topics: Acyl Coenzyme A; Anticholesteremic Agents; Cholesterol, LDL; Clinical Trials as Topic; Coronary Disease; Humans; Hypercholesterolemia; Lovastatin; Practice Guidelines as Topic; Risk Factors; Simvastatin	2000
More than cholesterol: the complexity of coronary artery disease. South Dakota journal of medicine, 2000, Volume: 53, Issue:11 Topics: Anticholesteremic Agents; Cholesterol, LDL; Coronary Disease; Disease Progression; Endothelium; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Risk Factors	2000
Statins in children: what do we know and what do we need to do? Current atherosclerosis reports, 2001, Volume: 3, Issue:1 Topics: Atorvastatin; Bezafibrate; Child; Child Welfare; Cost-Benefit Analysis; Drug Approval; Gemfibrozil; Heptanoic Acids; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lovastatin; Pyridines; Pyrroles; Simvastatin	2001
[Statins and stroke]. Annales d'endocrinologie, 2001, Volume: 62, Issue:1 Pt 2 Topics: Anticholesteremic Agents; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lovastatin; Risk Factors; Stroke	2001
[AFCAPS/TexCAPS [The Air Force/Texas Coronary Atherosclerosis Prevention Study]]. Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59 Suppl 3 Topics: Aged; Anticholesteremic Agents; Arteriosclerosis; Coronary Disease; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Randomized Controlled Trials as Topic; Risk Factors; Texas; Treatment Outcome	2001
Statins--similarities and differences. The American journal of managed care, 2001, Volume: 7, Issue:5 Suppl Topics: Anticholesteremic Agents; Coronary Disease; Humans; Hypercholesterolemia; Lipoproteins, LDL; Lovastatin; Structure-Activity Relationship; United States	2001
What do the statin trials tell us? The American journal of managed care, 2001, Volume: 7, Issue:5 Suppl Topics: Anticholesteremic Agents; Clinical Trials as Topic; Coronary Disease; Female; Humans; Hypercholesterolemia; Lipoproteins, LDL; Lovastatin; Male; Outcome Assessment, Health Care; Pravastatin; Stroke; United States	2001
[Substantiation of increasing doses of statins in clinical practice]. Terapevticheskii arkhiv, 2001, Volume: 73, Issue:4 Topics: Adult; Aged; Angiography; Animals; Anticholesteremic Agents; Arteriosclerosis; Atorvastatin; Clinical Trials as Topic; Colestipol; Coronary Disease; Dogs; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Lipids; Lovastatin; Male; Meta-Analysis as Topic; Middle Aged; Primates; Prospective Studies; Pyrroles; Retrospective Studies; Risk Factors; Simvastatin; Time Factors	2001
Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A-reductase inhibitors (statins). European journal of clinical pharmacology, 2001, Volume: 57, Issue:5 Topics: Atorvastatin; Drug Interactions; Drug Therapy, Combination; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Pravastatin; Pyridines; Pyrroles; Simvastatin	2001
Pharmacological interactions of statins. Atherosclerosis. Supplements, 2002, Volume: 3, Issue:1 Topics: Atorvastatin; Cytochrome P-450 Enzyme System; Drug Interactions; Drug Tolerance; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Muscular Diseases; Pyrroles; Rhabdomyolysis	2002
[Clinical evaluation of a selective inhibitor of cholesterol synthesis: pravastatin]. Minerva medica, 1992, Volume: 83, Issue:11 Topics: Adult; Animals; Anticholesteremic Agents; Cholesterol; Cholestyramine Resin; Clinical Trials as Topic; Drug Therapy, Combination; Female; Guinea Pigs; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Pravastatin; Rats; Risk Factors; Simvastatin; Time Factors	1992
The discovery and development of HMG-CoA reductase inhibitors. Journal of lipid research, 1992, Volume: 33, Issue:11 Topics: Animals; Anticholesteremic Agents; History, 20th Century; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin	1992
Lovastatin-induced rhabdomyolysis in the absence of concomitant drugs. The Annals of pharmacotherapy, 1992, Volume: 26, Issue:2 Topics: Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Rhabdomyolysis; Time Factors	1992
Clinical implications of new drugs for lowering plasma cholesterol concentrations. Drugs, 1991, Volume: 41, Issue:2 Topics: Anticholesteremic Agents; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipidemias; Lovastatin; Naphthalenes; Pravastatin; Simvastatin	1991
Lowering cholesterol with diet and lovastatin. Nutrition reviews, 1991, Volume: 49, Issue:10 Topics: Cholesterol; Dietary Fats; Humans; Hypercholesterolemia; Lovastatin	1991
[Hypercholesterolemia: therapeutic approach]. La Clinica terapeutica, 1991, Jun-30, Volume: 137, Issue:6 Topics: Adult; Aged; Anticholesteremic Agents; Enzyme Inhibitors; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Naphthalenes; Pravastatin; Simvastatin	1991
[Advance in drug treatment of primary and familial hypercholesterolemia]. Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, 1991, Volume: 11, Issue:5 Topics: Animals; Cholestyramine Resin; Drugs, Chinese Herbal; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lovastatin; Panax; Plants, Medicinal; Probucol	1991
Long-term clinical tolerance of lovastatin and simvastatin. Cardiology, 1990, Volume: 77 Suppl 4 Topics: Anticholesteremic Agents; Cholesterol; Drug Interactions; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Simvastatin	1990
Simvastatin. A review of its pharmacological properties and therapeutic potential in hypercholesterolaemia. Drugs, 1990, Volume: 40, Issue:4 Topics: Animals; Anticholesteremic Agents; Humans; Hypercholesterolemia; Lovastatin; Simvastatin	1990
HMG CoA reductase inhibitors in the treatment of hypercholesterolaemias. The Quarterly journal of medicine, 1990, Volume: 74, Issue:274 Topics: Anticholesteremic Agents; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Naphthalenes; Pravastatin; Simvastatin	1990
Reducing high blood cholesterol level with drugs. Cost-effectiveness of pharmacologic management. JAMA, 1990, Dec-19, Volume: 264, Issue:23 Topics: Anticholesteremic Agents; Cholestyramine Resin; Clinical Trials as Topic; Colestipol; Cost-Benefit Analysis; Drug Therapy, Combination; Gemfibrozil; Humans; Hypercholesterolemia; Lovastatin; Niacin; Probucol; Sensitivity and Specificity	1990
Reductase inhibitor therapy of hypercholesterolemia. Transactions of the American Clinical and Climatological Association, 1991, Volume: 102 Topics: Anticholesteremic Agents; Cholesterol, LDL; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Rhabdomyolysis; Simvastatin	1991
Simvastatin to lower cholesterol. Drug and therapeutics bulletin, 1990, Apr-17, Volume: 28, Issue:8 Topics: Anticholesteremic Agents; Humans; Hypercholesterolemia; Lovastatin; Simvastatin	1990
Cholesterol: myth or reality? Southern medical journal, 1990, Volume: 83, Issue:4 Topics: Age Factors; Aged; Cholesterol; Cholesterol, HDL; Clinical Trials as Topic; Coronary Disease; Evaluation Studies as Topic; Female; Follow-Up Studies; Health Education; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Reference Values; Risk Factors; Sex Factors	1990
[Maximal treatment of hypercholesteremia: what is possible?]. Arzneimittel-Forschung, 1990, Volume: 40, Issue:3A Topics: Anticholesteremic Agents; Combined Modality Therapy; Extracorporeal Circulation; Humans; Hypercholesterolemia; Lovastatin; Simvastatin	1990
Lovastatin: an HMG-CoA reductase inhibitor for lowering cholesterol. The Medical clinics of North America, 1989, Volume: 73, Issue:2 Topics: Cholesterol; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoproteins; Lovastatin	1989
Discovery, biochemistry and biology of lovastatin. The American journal of cardiology, 1988, Nov-11, Volume: 62, Issue:15 Topics: Animals; Chemical Phenomena; Chemistry; Cholesterol; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Liver; Lovastatin; Receptors, LDL	1988
Efficacy and long-term adverse effect pattern of lovastatin. The American journal of cardiology, 1988, Nov-11, Volume: 62, Issue:15 Topics: Alanine Transaminase; Clinical Trials as Topic; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Liver; Lovastatin; Muscular Diseases; Time Factors	1988
The clinical efficacy and safety of lovastatin and MK-733--an overview. European heart journal, 1987, Volume: 8 Suppl E Topics: Dose-Response Relationship, Drug; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoproteins; Lovastatin; Simvastatin	1987
3-Hydroxy-3-methylglutaryl--coenzyme A reductase inhibitors in the treatment of hypercholesterolemia. JAMA, 1987, Dec-25, Volume: 258, Issue:24 Topics: Adult; Animals; Anticholesteremic Agents; Child; Cholesterol, LDL; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin	1987
[Pharmacologic therapy of arteriosclerosis. II. New directions]. Medicina clinica, 1985, Jan-26, Volume: 84, Issue:3 Topics: Animals; Anticholesteremic Agents; Arachidonate Lipoxygenases; Arteriosclerosis; Blood Platelets; Cholesterol; Cholesterol Esters; Cholesterol, LDL; Enzyme Induction; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lipoxygenase Inhibitors; Lovastatin; Male; Models, Biological; Muscle, Smooth, Vascular; Naphthalenes; Phosphatidylcholine-Sterol O-Acyltransferase; Platelet Aggregation; Rats; Receptors, LDL	1985

Trials

279 trial(s) available for lovastatin and Elevated Cholesterol

Article	Year
Survivin down-regulation plays a crucial role in 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor-induced apoptosis in cancer. The Journal of biological chemistry, 2007, Jul-06, Volume: 282, Issue:27 Topics: Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cholesterol; Colonic Neoplasms; Diterpenes; Down-Regulation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent; Hypercholesterolemia; Inhibitor of Apoptosis Proteins; Lovastatin; Microtubule-Associated Proteins; Neoplasm Proteins; Phosphorylation; Polyisoprenyl Phosphates; Protein Prenylation; RNA Interference; Sesquiterpenes; Signal Transduction; Survivin	2007
Low dose red yeast rice with monacolin K lowers LDL cholesterol and blood pressure in Japanese with mild dyslipidemia: A multicenter, randomized trial. Asia Pacific journal of clinical nutrition, 2021, Volume: 30, Issue:3 Topics: Biological Products; Blood Pressure; Cholesterol, LDL; Dietary Supplements; Dyslipidemias; Humans; Hypercholesterolemia; Japan; Lovastatin	2021
Effectiveness and safety of red yeast rice predominated by monacolin K β-hydroxy acid form for hyperlipidemia treatment and management. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2022, Volume: 42, Issue:2 Topics: Biological Products; Cholesterol, LDL; Humans; Hydroxy Acids; Hypercholesterolemia; Hyperlipidemias; Lovastatin	2022
Effects of treatment with monacolin K, berberine and coenzyme Q10 on lipid metabolism in patients with moderate cardiovascular risk. Semergen, 2022, Volume: 48, Issue:6 Topics: Berberine; Cardiovascular Diseases; Cholesterol, LDL; Dietary Supplements; Heart Disease Risk Factors; Humans; Hypercholesterolemia; Lipid Metabolism; Lovastatin; Risk Factors; Treatment Outcome; Ubiquinone	2022
Randomized, Double-Blind, Placebo-Controlled Trial to Test the Effects of a Nutraceutical Combination Monacolin K-Free on the Lipid and Inflammatory Profile of Subjects with Hypercholesterolemia. Nutrients, 2022, Jul-08, Volume: 14, Issue:14 Topics: Adult; Aged; Biomarkers; C-Reactive Protein; Cholesterol, LDL; Dietary Supplements; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lipids; Lovastatin; Male; MicroRNAs; Middle Aged; Triglycerides	2022
Low Dose Monacolin K Combined with Coenzyme Q10, Grape Seed, and Olive Leaf Extracts Lowers LDL Cholesterol in Patients with Mild Dyslipidemia: A Multicenter, Randomized Controlled Trial. Nutrients, 2023, Jun-09, Volume: 15, Issue:12 Topics: Anticholesteremic Agents; Cholesterol, LDL; Dietary Supplements; Dyslipidemias; Humans; Hypercholesterolemia; Lovastatin; Olea; Vitis	2023
Efficacy of Nutraceutical Combination of Monacolin K, Berberine, and Silymarin on Lipid Profile and PCSK9 Plasma Level in a Cohort of Hypercholesterolemic Patients. Journal of medicinal food, 2020, Volume: 23, Issue:6 Topics: Berberine; Dietary Supplements; Humans; Hypercholesterolemia; Lipids; Lovastatin; Proprotein Convertase 9; Silymarin	2020
LDL-cholesterol lowering effect of a new dietary supplement: an open label, controlled, randomized, cross-over clinical trial in patients with mild-to-moderate hypercholesterolemia. Lipids in health and disease, 2018, May-24, Volume: 17, Issue:1 Topics: Adolescent; Adult; Aged; Analysis of Variance; Anticholesteremic Agents; Arginine; Ascorbic Acid; Cholesterol, HDL; Cholesterol, LDL; Cross-Over Studies; Dietary Supplements; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Severity of Illness Index; Triglycerides; Ubiquinone	2018
The short-term supplementation of monacolin K improves the lipid and metabolic patterns of hypertensive and hypercholesterolemic subjects at low cardiovascular risk. Food & function, 2018, Jul-17, Volume: 9, Issue:7 Topics: Adult; Biological Products; Blood Glucose; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Dietary Supplements; Female; Humans; Hypercholesterolemia; Hypertension; Lipids; Lovastatin; Male; Middle Aged; Risk Factors; Time Factors; Triglycerides	2018
Effect of Monacolin K and COQ10 supplementation in hypertensive and hypercholesterolemic subjects with metabolic syndrome. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 105 Topics: Aged; Anticholesteremic Agents; Blood Glucose; Cholesterol, HDL; Cholesterol, LDL; Diet, Mediterranean; Dietary Supplements; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Lovastatin; Male; Metabolic Syndrome; Middle Aged; Treatment Outcome; Triglycerides; Ubiquinone	2018
Relationship between adiponectin and leptin, and blood lipids in hyperlipidemia patients treated with red yeast rice. Forschende Komplementarmedizin (2006), 2013, Volume: 20, Issue:3 Topics: Adiponectin; Adult; Biological Products; Body Mass Index; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Dietary Supplements; Drug Combinations; Female; gamma-Aminobutyric Acid; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertriglyceridemia; Intention to Treat Analysis; Leptin; Lipids; Lovastatin; Male; Medicine, Chinese Traditional; Middle Aged; Treatment Outcome	2013
Berberine and monacolin effects on the cardiovascular risk profile of women with oestroprogestin-induced hypercholesterolemia. High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2014, Volume: 21, Issue:3 Topics: Adult; Anticholesteremic Agents; Berberine; Cardiovascular Diseases; Contraception; Contraceptives, Oral; Dietary Supplements; Drug Combinations; Ethinyl Estradiol; Female; Humans; Hypercholesterolemia; Lipid Metabolism; Lovastatin; Norpregnenes; Pilot Projects; Polycystic Ovary Syndrome; Prospective Studies; Risk Factors; Treatment Outcome	2014
Testing the Short-Term Efficacy of a Lipid-Lowering Nutraceutical in the Setting of Clinical Practice: A Multicenter Study. Journal of medicinal food, 2015, Volume: 18, Issue:11 Topics: Adult; Anticholesteremic Agents; Biological Products; Cholesterol; Cholesterol, LDL; Dietary Supplements; Fatty Acids, Unsaturated; Female; Humans; Hypercholesterolemia; Lipids; Lovastatin; Male; Metabolic Syndrome; Middle Aged; Phytosterols; Treatment Outcome; Triglycerides	2015
Low daily dose of 3 mg monacolin K from RYR reduces the concentration of LDL-C in a randomized, placebo-controlled intervention. Nutrition research (New York, N.Y.), 2016, Volume: 36, Issue:10 Topics: Biological Products; Cholesterol; Cholesterol, LDL; Dietary Supplements; Female; Folic Acid; Fungi; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged	2016
Should high creatine kinase discourage the initiation or continuance of statins for the treatment of hypercholesterolemia? Metabolism: clinical and experimental, 2009, Volume: 58, Issue:2 Topics: Atorvastatin; Cholesterol, LDL; Creatine Kinase; Fatty Acids, Monounsaturated; Fluorobenzenes; Fluvastatin; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Pravastatin; Prospective Studies; Pyrimidines; Pyrroles; Rhabdomyolysis; Rosuvastatin Calcium; Simvastatin; Sulfonamides	2009
Tolerability and effects on lipids of ezetimibe coadministered with pravastatin or simvastatin for twelve months: results from two open-label extension studies in hypercholesterolemic patients. Clinical therapeutics, 2008, Volume: 30, Issue:12 Topics: Adult; Aged; Anticholesteremic Agents; Arthralgia; Azetidines; Body Mass Index; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Combination; Ezetimibe; Female; Follow-Up Studies; Headache; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Patient Dropouts; Pravastatin; Respiratory Tract Infections; Simvastatin; Sinusitis; Treatment Outcome; Triglycerides	2008
Effect of folate supplementation on serum homocysteine and plasma total antioxidant capacity in hypercholesterolemic adults under lovastatin treatment: a double-blind randomized controlled clinical trial. Archives of medical research, 2009, Volume: 40, Issue:5 Topics: Adult; Anticholesteremic Agents; Antioxidants; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoproteins; Lovastatin; Male; Middle Aged; Vitamin B Complex	2009
A randomized, double-blind comparison of cerivastatin and lovastatin for treatment of primary hypercholesterolemia. Zhonghua yi xue za zhi = Chinese medical journal; Free China ed, 2002, Volume: 65, Issue:6 Topics: Adult; Aged; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Prospective Studies; Pyridines; Triglycerides	2002
Efficacy and safety of ezetimibe coadministered with lovastatin in primary hypercholesterolemia. The American journal of cardiology, 2003, Feb-15, Volume: 91, Issue:4 Topics: Aged; Anticholesteremic Agents; Apolipoprotein A-I; Apolipoproteins B; Azetidines; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hypercholesterolemia; Lipoprotein(a); Lovastatin; Male; Middle Aged; Practice Guidelines as Topic; Safety; Treatment Outcome; Triglycerides	2003
An economic analysis of the Atorvastatin Comparative Cholesterol Efficacy and Safety Study (ACCESS). PharmacoEconomics, 2003, Volume: 21 Suppl 1 Topics: Adult; Aged; Atorvastatin; Cholesterol, LDL; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Female; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Male; Middle Aged; Pravastatin; Pyrroles; Risk Factors; Simvastatin; Treatment Outcome	2003
A multicenter, randomized, double-blind clinical trial comparing the low-density lipoprotein cholesterol-lowering ability of lovastatin 10, 20, and 40 mg/d with fluvastatin 20 and 40 mg/d. Clinical therapeutics, 2003, Volume: 25, Issue:11 Topics: Cholesterol, LDL; Double-Blind Method; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Male; Middle Aged; Prospective Studies	2003
Efficacy of once-daily extended-release lovastatin as compared to immediate-release lovastatin in patients with hypercholesterolemia. Current medical research and opinion, 2004, Volume: 20, Issue:1 Topics: Adult; Aged; Anesthetics, Local; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cross-Over Studies; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Triglycerides	2004
Psychological and cognitive function: predictors of adherence with cholesterol lowering treatment. Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 2004, Volume: 27, Issue:2 Topics: Adult; Anticholesteremic Agents; Cognition; Emotions; Female; Humans; Hypercholesterolemia; Intelligence; Lovastatin; Male; Middle Aged; Patient Compliance; Personality; Personality Assessment; Predictive Value of Tests; Regression Analysis	2004
Efficacy of extended-release niacin with lovastatin for hypercholesterolemia: assessing all reasonable doses with innovative surface graph analysis. Archives of internal medicine, 2004, May-24, Volume: 164, Issue:10 Topics: Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Niacin; Probability; Reference Values; Risk Assessment; Severity of Illness Index; Treatment Outcome	2004
A community-based, randomized trial of ezetimibe added to statin therapy to attain NCEP ATP III goals for LDL cholesterol in hypercholesterolemic patients: the ezetimibe add-on to statin for effectiveness (EASE) trial. Mayo Clinic proceedings, 2005, Volume: 80, Issue:5 Topics: Aged; Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol, LDL; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Fatty Acids, Monounsaturated; Female; Fluvastatin; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Male; Middle Aged; Nephelometry and Turbidimetry; Practice Guidelines as Topic; Pravastatin; Pyrroles; Retrospective Studies; Risk Factors; Simvastatin	2005
A promoter polymorphism in cholesterol 7alpha-hydroxylase interacts with apolipoprotein E genotype in the LDL-lowering response to atorvastatin. Atherosclerosis, 2005, Volume: 180, Issue:2 Topics: Aged; Anticholesteremic Agents; Apolipoproteins E; Atorvastatin; Bile Acids and Salts; Cholesterol 7-alpha-Hydroxylase; Cholesterol, LDL; Double-Blind Method; Female; Genotype; Heptanoic Acids; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Placebos; Polymorphism, Genetic; Promoter Regions, Genetic; Pyrroles; Sex Factors; Treatment Outcome	2005
Genetically determined apo B levels and peak LDL density predict angiographic response to intensive lipid-lowering therapy. Journal of internal medicine, 2006, Volume: 259, Issue:4 Topics: Adult; Analysis of Variance; Apolipoproteins B; Colestipol; Coronary Angiography; Coronary Stenosis; Drug Therapy, Combination; Dyslipidemias; Genetic Predisposition to Disease; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lipoproteins, LDL; Lovastatin; Male; Middle Aged; Niacin; Pharmacogenetics; Treatment Outcome	2006
Comparison of a dietary portfolio diet of cholesterol-lowering foods and a statin on LDL particle size phenotype in hypercholesterolaemic participants. The British journal of nutrition, 2007, Volume: 98, Issue:6 Topics: Aged; Analysis of Variance; C-Reactive Protein; Cardiovascular Diseases; Cholesterol, LDL; Cross-Over Studies; Diet, Fat-Restricted; Dietary Fats; Dietary Fiber; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Particle Size; Phytosterols; Risk	2007
Effect of combining viscous fibre with lovastatin on serum lipids in normal human subjects. International journal of clinical practice, 2007, Volume: 61, Issue:11 Topics: Adolescent; Adult; Anticholesteremic Agents; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Combination; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Psyllium; Treatment Outcome; Triglycerides	2007
[The Scandinavian Simvastatin Survival Study: the clinical consequences]. Revista espanola de cardiologia, 1995, Volume: 48 Suppl 5 Topics: Adult; Aged; Anticholesteremic Agents; Coronary Disease; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Scandinavian and Nordic Countries; Simvastatin; Survivors	1995
Long-term efficacy and tolerability of simvastatin in a large cohort of elderly hypercholesterolemic patients. Atherosclerosis, 1995, Volume: 116, Issue:2 Topics: Aged; Aged, 80 and over; Anticholesteremic Agents; Cholesterol; Double-Blind Method; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Simvastatin	1995
Effects of bezafibrate and of 2 HMG-CoA reductase inhibitors on lipoprotein (a) level in hypercholesterolemic patients. International journal of clinical pharmacology and therapeutics, 1995, Volume: 33, Issue:6 Topics: Adult; Aged; Analysis of Variance; Anticholesteremic Agents; Bezafibrate; Cholesterol; Delayed-Action Preparations; Diet; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Lipoprotein(a); Lovastatin; Male; Middle Aged; Pravastatin; Receptors, LDL; Simvastatin	1995
Escape phenomenon of low-density lipoprotein cholesterol during lovastatin treatment. The American journal of cardiology, 1995, Jul-15, Volume: 76, Issue:3 Topics: Adult; Aged; Cholesterol, LDL; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Time Factors	1995
Effects of treatment with simvastatin and pravastatin on cognitive function in patients with hypercholesterolaemia. British journal of clinical pharmacology, 1995, Volume: 39, Issue:3 Topics: Adult; Anticholesteremic Agents; Cognition; Cross-Over Studies; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Pravastatin; Simvastatin	1995
Effect of simvastatin on Lp(a) concentrations. Clinical cardiology, 1995, Volume: 18, Issue:5 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Cholesterol, LDL; Dose-Response Relationship, Drug; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Linear Models; Lipoprotein(a); Lipoproteins, LDL; Lovastatin; Male; Middle Aged; Prospective Studies; Simvastatin	1995
Vitamin E in kidney transplantation: effect of treatment with simvastatin in hypercholesterolemia. Transplantation proceedings, 1995, Volume: 27, Issue:4 Topics: Anticholesteremic Agents; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Creatinine; Cyclosporine; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Kidney Transplantation; Lovastatin; Male; Middle Aged; Simvastatin; Time Factors; Triglycerides; Vitamin E	1995
The effect of lovastatin on early restenosis. Journal of clinical pharmacology, 1995, Volume: 35, Issue:6 Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Cholesterol, LDL; Coronary Angiography; Coronary Disease; Double-Blind Method; Exercise Test; Humans; Hypercholesterolemia; Incidence; Lovastatin; Male; Middle Aged; Prospective Studies; Recurrence	1995
Simvastatin treatment of hypercholesterolemia in patients with insulin dependent diabetes mellitus. International journal of clinical pharmacology and therapeutics, 1995, Volume: 33, Issue:1 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 1; Double-Blind Method; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Simvastatin	1995
[Therapy of hypercholesterolemia after heart transplantation with the HMG-CoA reductase inhibitor simvastatin in long-term follow-up]. Zeitschrift fur Kardiologie, 1995, Volume: 84, Issue:2 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol, LDL; Female; Heart Transplantation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Postoperative Complications; Prospective Studies; Simvastatin	1995
A comparison of the effects of simvastatin and pravastatin monotherapy on muscle histology and permeability in hypercholesterolaemic patients. British journal of clinical pharmacology, 1995, Volume: 39, Issue:2 Topics: Adult; Anticholesteremic Agents; Double-Blind Method; Ergometry; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Muscles; Permeability; Pravastatin; Prospective Studies; Simvastatin; Statistics as Topic	1995
A randomized trial to assess effectiveness and cost in clinical practice: rationale and design of the Cholesterol Reduction Intervention Study (CRIS). Controlled clinical trials, 1995, Volume: 16, Issue:1 Topics: Adult; Aged; Cholesterol, LDL; Coronary Disease; Cost-Benefit Analysis; Costs and Cost Analysis; Follow-Up Studies; Gemfibrozil; Humans; Hypercholesterolemia; Lovastatin; Middle Aged; Niacin; Patient Selection; Prospective Studies; Risk Factors; Treatment Outcome	1995
An empirical evaluation of the placebo run-in. Controlled clinical trials, 1995, Volume: 16, Issue:1 Topics: Aged; Cholesterol; Cholesterol, LDL; Educational Status; Feasibility Studies; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Lovastatin; Male; Patient Compliance; Patient Selection; Pilot Projects; Placebos; Research Design; Treatment Outcome	1995
Inhibition of thromboxane biosynthesis and platelet function by simvastatin in type IIa hypercholesterolemia. Arteriosclerosis, thrombosis, and vascular biology, 1995, Volume: 15, Issue:2 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lipid Metabolism; Lovastatin; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Simvastatin; Thromboxane A2	1995
[Therapeutic trial of simvastatin versus fenofibrate in primary hypercholesterolemia]. La Tunisie medicale, 1994, Volume: 72, Issue:11 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol, HDL; Cholesterol, LDL; Female; Fenofibrate; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides	1994
Changes in plasma lipid and apolipoprotein levels between heparin-induced extracorporeal low-density lipoprotein precipitation (HELP) treatments. The American journal of cardiology, 1995, Jun-01, Volume: 75, Issue:16 Topics: Adult; Apolipoproteins; Apolipoproteins A; Apolipoproteins B; Blood Component Removal; Chemical Precipitation; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Combined Modality Therapy; Extracorporeal Circulation; Female; Gemfibrozil; Heparin; Humans; Hypercholesterolemia; Hyperlipidemias; Lipids; Lipoproteins, LDL; Lovastatin; Male	1995
[Randomized, double-blind comparative study between pravastatin and lovastatin. Evaluation of efficacy and safety]. Arquivos brasileiros de cardiologia, 1994, Volume: 63, Issue:4 Topics: Adult; Aged; Cholesterol, LDL; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Pravastatin	1994
Effect of gemfibrozil versus lovastatin on increased serum lipoprotein(a) levels of patients with hypercholesterolemia. International journal of cardiology, 1995, Volume: 48, Issue:2 Topics: Adult; Aged; Cholesterol; Female; Gemfibrozil; Humans; Hypercholesterolemia; Lipoprotein(a); Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Lovastatin; Male; Middle Aged; Treatment Outcome; Triglycerides	1995
Effects of treatment with lovastatin and pravastatin on daytime cognitive performance. Clinical cardiology, 1995, Volume: 18, Issue:4 Topics: Adult; Affect; Cognition; Cross-Over Studies; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Pravastatin	1995
Prevention and treatment of graft vessel disease after heart transplantation. Transplantation proceedings, 1995, Volume: 27, Issue:3 Topics: Adult; Arteriosclerosis; Blood Component Removal; Cholesterol; Double-Blind Method; Female; Graft Occlusion, Vascular; Graft vs Host Disease; Heart Transplantation; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Oligopeptides; Peptides, Cyclic; Prospective Studies; Risk Factors; Simvastatin; Somatostatin; Tissue Donors	1995
Is a reduction of graft vessel disease by maximal treatment of hypercholesterolemia after heart transplantation possible? Transplantation proceedings, 1995, Volume: 27, Issue:3 Topics: Adult; Coronary Disease; Cyclosporine; Female; Graft Occlusion, Vascular; Graft Rejection; Heart Transplantation; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin	1995
Enhanced low-density lipoprotein cholesterol reduction and cost-effectiveness by low-dose colestipol plus lovastatin combination therapy. The American journal of cardiology, 1995, Jan-01, Volume: 75, Issue:1 Topics: Apolipoproteins; Cholesterol, LDL; Colestipol; Cost-Benefit Analysis; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Lipids; Lipoproteins; Lovastatin; Male; Middle Aged	1995
Decreases in serum ubiquinone concentrations do not result in reduced levels in muscle tissue during short-term simvastatin treatment in humans. Clinical pharmacology and therapeutics, 1995, Volume: 57, Issue:1 Topics: Acyl Coenzyme A; Adult; Anticholesteremic Agents; Cholesterol; Chromatography, High Pressure Liquid; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Muscles; Simvastatin; Ubiquinone	1995
The effect of cholesterol-lowering and antioxidant therapy on endothelium-dependent coronary vasomotion. The New England journal of medicine, 1995, Feb-23, Volume: 332, Issue:8 Topics: Acetylcholine; Anticholesteremic Agents; Antioxidants; Cholestyramine Resin; Coronary Artery Disease; Endothelium, Vascular; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Probucol; Regression Analysis; Vasoconstriction; Vasodilation	1995
Central nervous system effects of HMG CoA reductase inhibitors: lovastatin and pravastatin on sleep and cognitive performance in patients with hypercholesterolemia. Journal of clinical pharmacology, 1994, Volume: 34, Issue:10 Topics: Adult; Affect; Aged; Cholesterol, LDL; Cognition; Cross-Over Studies; Double-Blind Method; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lipoproteins; Lovastatin; Male; Middle Aged; Polysomnography; Pravastatin; Psychomotor Performance; Sleep	1994
Efficacy of low-dose cholesterol-lowering drug therapy in men with moderate hypercholesterolemia. Archives of internal medicine, 1995, Feb-27, Volume: 155, Issue:4 Topics: Adult; Aged; Anticholesteremic Agents; Cholestyramine Resin; Drug Therapy, Combination; Humans; Hypercholesterolemia; Lipids; Lipoproteins; Lovastatin; Male; Middle Aged; Severity of Illness Index; Treatment Outcome	1995
[Hypercholesterolemia--a clinical problem in heart transplantation. A therapeutic trial with low-dose lovastatin]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1995, Jan-30, Volume: 115, Issue:3 Topics: Adult; Aged; Female; Heart Transplantation; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Retrospective Studies	1995
Gender and diet interactions with simvastatin treatment. Atherosclerosis, 1994, Sep-30, Volume: 110, Issue:1 Topics: Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Dietary Fats; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Sex Factors; Simvastatin; Triglycerides	1994
HBPRCA Astra Award. Therapeutic restoration of endothelial function in hypercholesterolaemic subjects: effect of fish oils. Clinical and experimental pharmacology & physiology, 1994, Volume: 21, Issue:10 Topics: Acetylcholine; Adult; Australia; Awards and Prizes; Cholesterol; Cholesterol, LDL; Cholestyramine Resin; Drug Therapy, Combination; Endothelium, Vascular; Female; Fish Oils; Forearm; Humans; Hypercholesterolemia; Hypertension; Lovastatin; Male; Middle Aged; Regional Blood Flow; Simvastatin	1994
[Moderate hypercholesterolemia and coronary disease: the MAAS study and the 4S study]. Revue medicale de Liege, 1995, Volume: 50, Issue:1 Topics: Anticholesteremic Agents; Cholesterol, LDL; Coronary Angiography; Coronary Artery Disease; Humans; Hydroxymethylglutaryl-CoA Synthase; Hypercholesterolemia; Lovastatin; Middle Aged; Primary Prevention; Risk Factors; Simvastatin	1995
[Can hyperlipidemia after heart transplantation be optimally and safely treated?]. Helvetica chirurgica acta, 1994, Volume: 60, Issue:6 Topics: Adult; Aged; Cholesterol, HDL; Cholesterol, LDL; Female; Heart Transplantation; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lovastatin; Male; Middle Aged; Prospective Studies; Simvastatin	1994
Dose-response of simvastatin in primary hypercholesterolemia. Journal of cardiovascular pharmacology, 1994, Volume: 24, Issue:6 Topics: Anticholesteremic Agents; Diet; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides	1994
Efficacy of low-density-lipoprotein lowering with statins. Lancet (London, England), 1994, Sep-03, Volume: 344, Issue:8923 Topics: Cholesterol, LDL; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Lovastatin; Simvastatin	1994
Effects of long-term simvastatin treatment on testicular and adrenal steroidogenesis in hypercholesterolemic patients. Journal of endocrinological investigation, 1994, Volume: 17, Issue:4 Topics: Adrenocorticotropic Hormone; Adult; Anticholesteremic Agents; Chorionic Gonadotropin; Hormones; Humans; Hypercholesterolemia; Hypothalamo-Hypophyseal System; Lipid Metabolism; Lovastatin; Male; Middle Aged; Pituitary-Adrenal System; Simvastatin; Steroids; Testis; Time Factors	1994
Clinical efficacy and pharmacokinetics of HMG-CoA reductase inhibitors in heart transplant patients treated with cyclosporin A. Transplantation proceedings, 1994, Volume: 26, Issue:5 Topics: Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Creatinine; Cyclosporine; Follow-Up Studies; Heart Transplantation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Pravastatin; Simvastatin; Time Factors; Triglycerides	1994
Expanded Clinical Evaluation of Lovastatin (EXCEL) study results: two-year efficacy and safety follow-up. The American journal of cardiology, 1994, Oct-01, Volume: 74, Issue:7 Topics: Alanine Transaminase; Cholesterol, HDL; Cholesterol, LDL; Cohort Studies; Creatine Kinase; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Life Tables; Liver; Lovastatin; Male; Middle Aged; Muscular Diseases; Triglycerides; United States	1994
Effects of lovastatin therapy on plasminogen activator inhibitor-1 antigen levels. The American journal of cardiology, 1994, Oct-01, Volume: 74, Issue:7 Topics: Adult; Aged; Female; Fibrinolysis; Humans; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Plasminogen Activator Inhibitor 1	1994
Comparison of the effectiveness of lovastatin therapy for hypercholesterolemia after heart transplantation between patients with and without pretransplant atherosclerotic coronary artery disease. The American journal of cardiology, 1994, Oct-15, Volume: 74, Issue:8 Topics: Cholesterol; Coronary Artery Disease; Female; Heart Transplantation; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Postoperative Complications; Retrospective Studies; Treatment Outcome; Triglycerides	1994
Serum ubiquinone concentrations after short- and long-term treatment with HMG-CoA reductase inhibitors. European journal of clinical pharmacology, 1994, Volume: 46, Issue:4 Topics: Adult; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin; Time Factors; Ubiquinone	1994
Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S) Lancet (London, England), 1994, Nov-19, Volume: 344, Issue:8934 Topics: Adult; Aged; Angina Pectoris; Anticholesteremic Agents; Cardiovascular Diseases; Cholesterol; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Myocardial Infarction; Risk Factors; Simvastatin; Survival Analysis	1994
[Effect of lovastatin on serum lipids and lipoproteins. Hungarian multicenter, open-label study]. Orvosi hetilap, 1994, Oct-02, Volume: 135, Issue:40 Topics: Adult; Cholesterol; Female; Humans; Hypercholesterolemia; Lipids; Lipoproteins; Lovastatin; Male; Middle Aged; Treatment Outcome; Triglycerides	1994
[Lovastatin in the treatment of hypercholesterolemia]. Polskie Archiwum Medycyny Wewnetrznej, 1994, Volume: 92, Issue:1 Topics: Adult; Aged; Cholesterol; Cholesterol, HDL; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Triglycerides	1994
Effects of lovastatin on ApoA- and ApoB-containing lipoproteins. Families in a subpopulation of patients participating in the Monitored Atherosclerosis Regression Study (MARS). Arteriosclerosis and thrombosis : a journal of vascular biology, 1994, Volume: 14, Issue:12 Topics: Adult; Aged; Apolipoproteins A; Apolipoproteins B; Cholesterol; Coronary Artery Disease; Disease Progression; Drug Monitoring; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Triglycerides	1994
Comparative efficacy and tolerability of 5 and 10 mg simvastatin and 10 mg pravastatin in moderate primary hypercholesterolemia. Simvastatin Pravastatin European Study Group. Cardiology, 1994, Volume: 85, Issue:3-4 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Pravastatin; Simvastatin	1994
Low-dose simvastatin is a well-tolerated and efficacious cholesterol-lowering agent in ciclosporin-treated kidney transplant recipients: double-blind, randomized, placebo-controlled study in 40 patients. Nephron, 1994, Volume: 68, Issue:1 Topics: Adult; Anticholesteremic Agents; Cholesterol; Cyclosporine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Kidney Transplantation; Lovastatin; Male; Middle Aged; Placebos; Risk Factors; Simvastatin	1994
Three-year follow-up of the Oxford Cholesterol Study: assessment of the efficacy and safety of simvastatin in preparation for a large mortality study. European heart journal, 1994, Volume: 15, Issue:2 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Coronary Disease; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Lipids; Liver Function Tests; Lovastatin; Male; Middle Aged; Myocardial Infarction; Prospective Studies; Simvastatin; Survival Analysis; Survival Rate; Treatment Outcome	1994
Comparative effects of lovastatin and niacin in primary hypercholesterolemia. A prospective trial. Archives of internal medicine, 1994, Jul-25, Volume: 154, Issue:14 Topics: Adult; Aged; Female; Humans; Hypercholesterolemia; Lipids; Lipoproteins; Lovastatin; Male; Middle Aged; Niacin	1994
Associations of cholesterol lowering by statins with anger and hostility in hypercholesterolemic men. Biological psychiatry, 1994, Apr-15, Volume: 35, Issue:8 Topics: Adult; Aged; Anger; Cholesterol; Double-Blind Method; Hostility; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Pravastatin	1994
Simvastatin in non-insulin-dependent diabetes mellitus: effect on serum lipids, lipoproteins and haemostatic measures. Diabetes research and clinical practice, 1994, Volume: 23, Issue:2 Topics: Adult; Aged; Apolipoproteins B; Blood Glucose; Cholesterol, LDL; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Hemostasis; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lipids; Lipoproteins; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides	1994
Efficacy and tolerability of lovastatin in hypercholesterolemia in patients with systemic hypertension. The American journal of cardiology, 1993, Jan-01, Volume: 71, Issue:1 Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Diuretics; Drug Tolerance; Female; Humans; Hypercholesterolemia; Hypertension; Lovastatin; Male; Middle Aged; Retrospective Studies; Time Factors; Triglycerides	1993
Benefits of lipid-lowering therapy in men with elevated apolipoprotein B are not confined to those with very high low density lipoprotein cholesterol. Journal of the American College of Cardiology, 1994, Mar-15, Volume: 23, Issue:4 Topics: Adult; Analysis of Variance; Anticholesteremic Agents; Apolipoproteins B; Cholesterol, LDL; Colestipol; Coronary Angiography; Coronary Disease; Double-Blind Method; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Niacin; Treatment Outcome	1994
Comparative efficacy and safety of micronized fenofibrate and simvastatin in patients with primary type IIa or IIb hyperlipidemia. Archives of internal medicine, 1994, Feb-28, Volume: 154, Issue:4 Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Cholesterol, LDL; Double-Blind Method; Female; Fenofibrate; Humans; Hypercholesterolemia; Hypertriglyceridemia; Lovastatin; Male; Middle Aged; Prognosis; Simvastatin; Triglycerides	1994
Efficacy and tolerability of simvastatin 20 mg vs pravastatin 20 mg in patients with primary hypercholesterolemia. European Study Group. Acta cardiologica, 1993, Volume: 48, Issue:6 Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Apolipoprotein A-I; Apolipoproteins B; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Drug Tolerance; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Pravastatin; Simvastatin; Triglycerides	1993
Cholesterol lowering in the elderly. Results of the Cholesterol Reduction in Seniors Program (CRISP) pilot study. Archives of internal medicine, 1994, Mar-14, Volume: 154, Issue:5 Topics: Aged; Combined Modality Therapy; Double-Blind Method; Feasibility Studies; Female; Humans; Hypercholesterolemia; Lipids; Lovastatin; Male; Pilot Projects; Quality of Life; Treatment Outcome; Vision, Ocular	1994
[An evaluation of the hypolipidemic effects of lovastatin in primary hypercholesterolemia. A multicenter study]. Kardiologiia, 1993, Volume: 33, Issue:11 Topics: Adult; Aged; Drug Tolerance; Female; Humans; Hypercholesterolemia; Lipids; Lipoproteins; Lovastatin; Male; Middle Aged; Myocardial Ischemia; Time Factors; USSR	1993
Comparison of effects on sleep of lovastatin and pravastatin in hypercholesterolemia. The American journal of cardiology, 1994, May-01, Volume: 73, Issue:12 Topics: Adult; Aged; Double-Blind Method; Humans; Hypercholesterolemia; Lipoproteins; Lovastatin; Male; Middle Aged; Polysomnography; Pravastatin; Sleep	1994
[Efficacy and tolerability of simvastatin and omega-3 fatty acid combination in patients with coronary disease, hypercholesterolemia and hypertriglyceridemia]. Cardiologia (Rome, Italy), 1993, Volume: 38, Issue:12 Topics: Aged; Anticholesteremic Agents; Coronary Disease; Drug Tolerance; Fatty Acids, Omega-3; Female; Humans; Hypercholesterolemia; Hypertriglyceridemia; Hypolipidemic Agents; Lovastatin; Male; Middle Aged; Simvastatin	1993
Effectiveness of low-dose lovastatin combined with low-dose colestipol in moderate to severe primary hypercholesterolaemia. Scandinavian journal of clinical and laboratory investigation, 1993, Volume: 53, Issue:5 Topics: Adult; Aged; Cholesterol; Colestipol; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged	1993
Effect and tolerability of combining lovastatin with nifedipine or lisinopril. American journal of hypertension, 1993, Volume: 6, Issue:8 Topics: Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Hypertension; Lisinopril; Lovastatin; Male; Middle Aged; Nifedipine; Quality of Life; Risk Factors	1993
Treating hypercholesterolaemia with HMG CoA reductase inhibitors: a direct comparison of simvastatin and pravastatin. Australian and New Zealand journal of medicine, 1993, Volume: 23, Issue:4 Topics: Adult; Aged; Anticholesteremic Agents; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Pravastatin; Simvastatin	1993
Renal function and insulin sensitivity during simvastatin treatment in type 2 (non-insulin-dependent) diabetic patients with microalbuminuria. Diabetologia, 1993, Volume: 36, Issue:10 Topics: Aged; Albuminuria; Anticholesteremic Agents; Apolipoproteins B; Biomarkers; Blood Glucose; Blood Pressure; Cholesterol; Cholesterol, LDL; Diabetes Mellitus, Type 2; Double-Blind Method; Energy Intake; Female; Fructosamine; Glomerular Filtration Rate; Glycated Hemoglobin; Hexosamines; Humans; Hypercholesterolemia; Insulin; Kidney; Lovastatin; Male; Placebos; Simvastatin; Time Factors	1993
Simvastatin therapy for hypercholesterolemic patients with nephrotic syndrome or significant proteinuria. Kidney international, 1993, Volume: 44, Issue:5 Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Apolipoprotein B-100; Apolipoproteins B; Cholesterol, HDL; Cholesterol, LDL; Creatinine; Double-Blind Method; Female; Humans; Hypercholesterolemia; Inulin; Lovastatin; Male; Middle Aged; Nephrotic Syndrome; Placebos; Proteinuria; Simvastatin; Triglycerides	1993
[Reductions in lipid fraction plasma levels induced by simvastatin and bezafibrate. Brazilian multicenter study]. Arquivos brasileiros de cardiologia, 1993, Volume: 60, Issue:6 Topics: Bezafibrate; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Program Evaluation; Time Factors	1993
[Lovastatin in the treatment of hypercholesterolemia in non-insulin-dependent diabetes mellitus patients]. Arquivos brasileiros de cardiologia, 1993, Volume: 61, Issue:1 Topics: Aged; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Diabetes Mellitus, Type 2; Drug Administration Schedule; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged	1993
Effects of lovastatin on natural killer cell function and other immunological parameters in man. Journal of clinical immunology, 1993, Volume: 13, Issue:6 Topics: Adult; Aged; B-Lymphocytes; Cytotoxicity, Immunologic; Double-Blind Method; Female; Humans; Hypercholesterolemia; Killer Cells, Natural; Leukocyte Count; Lipids; Lovastatin; Lymphocyte Activation; Male; Middle Aged; Phytohemagglutinins; T-Lymphocytes	1993
Hypercholesterolemia in postmenopausal women. Metabolic defects and response to low-dose lovastatin. JAMA, 1994, Feb-09, Volume: 271, Issue:6 Topics: Aged; Apolipoproteins B; Cholesterol, LDL; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hypercholesterolemia; Lipoproteins; Lipoproteins, LDL; Lipoproteins, VLDL; Lovastatin; Middle Aged; Postmenopause	1994
Lovastatin and the human lens; results of a two year study. The MSDRL Study Group. Optometry and vision science : official publication of the American Academy of Optometry, 1993, Volume: 70, Issue:11 Topics: Cataract; Contrast Sensitivity; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Image Processing, Computer-Assisted; Lens, Crystalline; Longitudinal Studies; Lovastatin; Male; Middle Aged; Photography; Visual Acuity	1993
Treatment of primary hypercholesterolaemia. Short-term efficacy and safety of increasing doses of simvastatin and pravastatin: a double-blind comparative study. Journal of internal medicine, 1993, Volume: 234, Issue:1 Topics: Adult; Aged; Anticholesteremic Agents; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Pravastatin; Simvastatin; Treatment Outcome	1993
Comparison of the short term efficacy and tolerability of lovastatin and simvastatin in the management of primary hypercholesterolemia. The Canadian journal of cardiology, 1993, Volume: 9, Issue:5 Topics: Anticholesteremic Agents; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin; Time Factors	1993
Effect of lovastatin on serum lipid profile in the treatment of dyslipoproteinaemia in uraemic patients on continuous ambulatory peritoneal dialysis. Australian and New Zealand journal of medicine, 1993, Volume: 23, Issue:3 Topics: Female; Humans; Hypercholesterolemia; Hypertriglyceridemia; Lipids; Lovastatin; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Single-Blind Method; Uremia	1993
Lovastatin does not affect oral glucose tolerance in hypercholesterolemic patients. Journal of clinical pharmacology, 1993, Volume: 33, Issue:6 Topics: Adult; Aged; Blood Glucose; Cholesterol, LDL; Double-Blind Method; Fasting; Female; Glucose Tolerance Test; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Time Factors; Triglycerides	1993
[Comparison of 2 cholesterol synthesis inhibitors (simvastatin and pravastatin)]. Schweizerische medizinische Wochenschrift, 1993, Aug-21, Volume: 123, Issue:33 Topics: Anticholesteremic Agents; Cholesterol; Humans; Hypercholesterolemia; Lovastatin; Pravastatin; Simvastatin	1993
[Comparison of the efficacy between simvastatin and gemfibrozil in primary hypercholesterolemia]. La Revue de medecine interne, 1993, Volume: 14, Issue:4 Topics: Adult; Aged; Double-Blind Method; Female; Gemfibrozil; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lovastatin; Male; Middle Aged; Simvastatin	1993
Lovastatin treatment of dyslipoproteinemia in patients on continuous ambulatory peritoneal dialysis. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis, 1993, Volume: 13 Suppl 2 Topics: Adult; Aged; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Single-Blind Method	1993
Design and baseline results of the Scandinavian Simvastatin Survival Study of patients with stable angina and/or previous myocardial infarction. The American journal of cardiology, 1993, Feb-15, Volume: 71, Issue:5 Topics: Adult; Aged; Angina Pectoris; Anticholesteremic Agents; Double-Blind Method; Ethics, Medical; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Myocardial Infarction; Scandinavian and Nordic Countries; Simvastatin; Time Factors	1993
HMGCoA reductase inhibitors lovastatin and simvastatin in the treatment of hypercholesterolemia after renal transplantation. Transplantation proceedings, 1993, Volume: 25, Issue:1 Pt 2 Topics: Adult; Anticholesteremic Agents; Apolipoproteins; Body Mass Index; Body Weight; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Immunosuppression Therapy; Kidney Transplantation; Lipids; Lipoproteins; Lovastatin; Male; Postoperative Complications; Proteinuria; Simvastatin; Triglycerides	1993
A multicenter comparative trial of lovastatin and pravastatin in the treatment of hypercholesterolemia. The Lovastatin Pravastatin Study Group. The American journal of cardiology, 1993, Apr-01, Volume: 71, Issue:10 Topics: Cholesterol, LDL; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lipoproteins; Liver Function Tests; Lovastatin; Male; Middle Aged; Pravastatin; Sleep	1993
Simvastatin in severe primary hypercholesterolemia: efficacy, safety, and tolerability in 595 patients over 18 weeks. The Principal Investigators. Clinical cardiology, 1993, Volume: 16, Issue:4 Topics: Adult; Aged; Alanine Transaminase; Anticholesteremic Agents; Aspartate Aminotransferases; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Creatine Kinase; Digestive System Diseases; Drug Tolerance; Female; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Placebos; Safety; Simvastatin; Triglycerides	1993
Relative safety and efficacy of pravastatin. Clinical pharmacy, 1993, Volume: 12, Issue:4 Topics: Humans; Hypercholesterolemia; Lovastatin; Pravastatin	1993
Evidence of plasma CoQ10-lowering effect by HMG-CoA reductase inhibitors: a double-blind, placebo-controlled study. Journal of clinical pharmacology, 1993, Volume: 33, Issue:3 Topics: Adult; Cholesterol; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Pravastatin; Simvastatin; Ubiquinone	1993
The efficacy of intensive dietary therapy alone or combined with lovastatin in outpatients with hypercholesterolemia. The New England journal of medicine, 1993, Apr-29, Volume: 328, Issue:17 Topics: Apolipoproteins; Cholesterol; Cholesterol, Dietary; Cholesterol, HDL; Combined Modality Therapy; Dietary Fats; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Triglycerides	1993
The effects of simvastatin and pravastatin on objective and subjective measures of nocturnal sleep: a comparison of two structurally different HMG CoA reductase inhibitors in patients with primary moderate hypercholesterolaemia. British journal of clinical pharmacology, 1993, Volume: 35, Issue:3 Topics: Adult; Aged; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Polysomnography; Pravastatin; Simvastatin; Sleep; Sleep Wake Disorders	1993
Efficacy and tolerability of lovastatin in 3390 women with moderate hypercholesterolemia. Annals of internal medicine, 1993, Jun-01, Volume: 118, Issue:11 Topics: Aged; Cholesterol, HDL; Cholesterol, LDL; Creatine Kinase; Double-Blind Method; Estrogen Replacement Therapy; Female; Humans; Hypercholesterolemia; Lovastatin; Middle Aged; Muscular Diseases; Sex Factors; Transaminases	1993
Lovastatin 5-year safety and efficacy study. Lovastatin Study Groups I through IV. Archives of internal medicine, 1993, May-10, Volume: 153, Issue:9 Topics: Cardiovascular Diseases; Cause of Death; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Treatment Outcome; Visual Acuity	1993
[Effectiveness and tolerability of simvastatin in subjects with primary hypercholesterolemia. Multicenter study]. La Clinica terapeutica, 1993, Volume: 142, Issue:3 Topics: Aged; Anticholesteremic Agents; Dose-Response Relationship, Drug; Drug Evaluation; Female; Humans; Hypercholesterolemia; Lipoproteins, HDL; Lipoproteins, LDL; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides	1993
Comparison of the efficacy, safety and tolerability of simvastatin and pravastatin for hypercholesterolemia. The Simvastatin Pravastatin Study Group. The American journal of cardiology, 1993, Jun-15, Volume: 71, Issue:16 Topics: Adult; Aged; Anticholesteremic Agents; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Pravastatin; Simvastatin; Sleep; Treatment Outcome	1993
Statin therapy and CHD. Lancet (London, England), 1996, Jan-13, Volume: 347, Issue:8994 Topics: Anticholesteremic Agents; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Simvastatin	1996
Effects of simvastatin and cholestyramine on bile lipid composition and gall bladder motility in patients with hypercholesterolaemia. Gut, 1995, Volume: 37, Issue:5 Topics: Anticholesteremic Agents; Bile; Cholesterol; Cholestyramine Resin; Drug Therapy, Combination; Female; Gallbladder; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Prospective Studies; Simvastatin; Ultrasonography	1995
[Effectiveness, tolerance and safety of simvastatin in comparison with bezafibrate in treatment of hypercholesterolemia]. Wiener medizinische Wochenschrift (1946), 1995, Volume: 145, Issue:21 Topics: Adult; Aged; Anticholesteremic Agents; Apolipoproteins; Bezafibrate; Cholesterol, HDL; Cholesterol, LDL; Combined Modality Therapy; Diet, Fat-Restricted; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides	1995
Cholesterol-reduction intervention study (CRIS): a randomized trial to assess effectiveness and costs in clinical practice. Archives of internal medicine, 1996, Apr-08, Volume: 156, Issue:7 Topics: Adult; Aged; Anticholesteremic Agents; Cost-Benefit Analysis; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Niacin; Treatment Outcome	1996
Effects of colestipol alone and in combination with simvastatin on apolipoprotein B metabolism. Arteriosclerosis, thrombosis, and vascular biology, 1996, Volume: 16, Issue:2 Topics: Adult; Apolipoproteins B; Colestipol; Drug Combinations; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lipids; Lipoproteins; Lovastatin; Male; Middle Aged; Simvastatin	1996
Comparison of the effects on quality of life and of the efficacy and tolerability of lovastatin versus pravastatin. The Quality of Life Multicenter Group. The American journal of cardiology, 1996, Mar-01, Volume: 77, Issue:7 Topics: Adult; Anticholesteremic Agents; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Pravastatin; Quality of Life; Treatment Outcome	1996
Physician extenders for cost-effective management of hypercholesterolemia. Journal of general internal medicine, 1996, Volume: 11, Issue:5 Topics: Anticholesteremic Agents; Cholesterol; Cost-Benefit Analysis; Diet Therapy; Follow-Up Studies; Humans; Hypercholesterolemia; Lipoproteins; Lovastatin; Middle Aged; Physician Assistants; Prospective Studies; Treatment Outcome	1996
Testicular function in hypercholesterolemic male patients during prolonged simvastatin treatment. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1996, Volume: 28, Issue:4 Topics: Androgens; Anticholesteremic Agents; Apolipoproteins; Chorionic Gonadotropin; Estradiol; Humans; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Simvastatin; Testis; Testosterone	1996
Efficacy and tolerability of lovastatin in 459 African-Americans with hypercholesterolemia. The American journal of cardiology, 1996, Aug-15, Volume: 78, Issue:4 Topics: Anticholesteremic Agents; Black or African American; Black People; Cholesterol; Cholesterol, LDL; Creatine Kinase; Dose-Response Relationship, Drug; Double-Blind Method; Drug Tolerance; Female; Humans; Hypercholesterolemia; Incidence; Lovastatin; Male; Middle Aged; Placebos; Safety; Triglycerides	1996
[Multicenter comparative study on safety, tolerance, and effectiveness of lovastatin combined or not with cholestyramine, and gemfibrozil combined or not with cholestyramine in the treatment of primary hypercholesterolemia]. Medicina clinica, 1996, May-25, Volume: 106, Issue:20 Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Cholesterol; Cholestyramine Resin; Double-Blind Method; Drug Therapy, Combination; Female; Gemfibrozil; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lovastatin; Male; Middle Aged; Triglycerides	1996
Effects of short-term reduction in serum cholesterol with simvastatin in patients with stable angina pectoris and mild to moderate hypercholesterolemia. The American journal of cardiology, 1996, Oct-01, Volume: 78, Issue:7 Topics: Analysis of Variance; Angina Pectoris; Anticholesteremic Agents; Cholesterol; Cholesterol, LDL; Electrocardiography; Exercise Test; Forearm; Humans; Hypercholesterolemia; Lovastatin; Middle Aged; Regional Blood Flow; Simvastatin; Single-Blind Method	1996
Safety and tolerability of cholesterol lowering with simvastatin during 5 years in the Scandinavian Simvastatin Survival Study. Archives of internal medicine, 1996, Oct-14, Volume: 156, Issue:18 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Coronary Disease; Double-Blind Method; Humans; Hypercholesterolemia; Lovastatin; Middle Aged; Simvastatin	1996
Lipid-lowering effects of simvastatin and gemfibrozil in CAPD patients: a prospective cross-over study. Advances in peritoneal dialysis. Conference on Peritoneal Dialysis, 1996, Volume: 12 Topics: Adult; Aged; Cholesterol; Combined Modality Therapy; Cross-Over Studies; Diet, Fat-Restricted; Female; Gemfibrozil; Humans; Hypercholesterolemia; Hypertriglyceridemia; Hypolipidemic Agents; Kidney Failure, Chronic; Lovastatin; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Prospective Studies; Simvastatin; Triglycerides	1996
Meeting national cholesterol education goals in clinical practice--a comparison of lovastatin and fluvastatin in primary prevention. The American journal of cardiology, 1996, Sep-26, Volume: 78, Issue:6A Topics: Fatty Acids, Monounsaturated; Female; Fluvastatin; Health Education; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Male; Middle Aged	1996
Low density lipoprotein apheresis improves regional myocardial perfusion in patients with hypercholesterolemia and extensive coronary artery disease. LDL-Apheresis Atherosclerosis Regression Study (LAARS). Journal of the American College of Cardiology, 1996, Volume: 28, Issue:7 Topics: Adult; Aged; Angiography, Digital Subtraction; Anticholesteremic Agents; Blood Component Removal; Combined Modality Therapy; Coronary Angiography; Coronary Artery Disease; Coronary Circulation; Female; Humans; Hypercholesterolemia; Lipoproteins, LDL; Lovastatin; Male; Middle Aged; Simvastatin	1996
Effect of apheresis of low-density lipoprotein on peripheral vascular disease in hypercholesterolemic patients with coronary artery disease. Annals of internal medicine, 1996, Dec-15, Volume: 125, Issue:12 Topics: Adult; Aged; Anticholesteremic Agents; Blood Component Removal; Cholesterol, LDL; Combined Modality Therapy; Coronary Artery Disease; Disease Progression; Enzyme Inhibitors; Hemodynamics; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Peripheral Vascular Diseases; Simvastatin	1996
The effect of aggressive lowering of low-density lipoprotein cholesterol levels and low-dose anticoagulation on obstructive changes in saphenous-vein coronary-artery bypass grafts. The New England journal of medicine, 1997, Jan-16, Volume: 336, Issue:3 Topics: Adult; Aged; Anticholesteremic Agents; Anticoagulants; Cholesterol, LDL; Cholestyramine Resin; Coronary Angiography; Coronary Artery Bypass; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy, Combination; Female; Graft Occlusion, Vascular; Humans; Hypercholesterolemia; Life Tables; Lovastatin; Male; Middle Aged; Saphenous Vein; Treatment Outcome; Warfarin	1997
Effect of pharmacologic lipid lowering on health-related quality of life in older persons: results from the Cholesterol Reduction in Seniors Program (CRISP) Pilot Study. Journal of the American Geriatrics Society, 1997, Volume: 45, Issue:1 Topics: Activities of Daily Living; Aged; Aged, 80 and over; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Prospective Studies; Quality of Life; Surveys and Questionnaires	1997
The effect of simvastatin on progression of coronary artery disease. The Multicenter coronary Intervention Study (CIS). European heart journal, 1997, Volume: 18, Issue:2 Topics: Adult; Anticholesteremic Agents; Cholesterol, LDL; Coronary Disease; Disease Progression; Dose-Response Relationship, Drug; Double-Blind Method; Follow-Up Studies; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Prospective Studies; Simvastatin; Treatment Outcome	1997
Randomized placebo-controlled study of the effects of simvastatin on haemostatic variables, lipoproteins and free fatty acids. The Oxford Cholesterol Study Group. European heart journal, 1997, Volume: 18, Issue:2 Topics: Adult; Aged; Chromatography, Thin Layer; Coronary Disease; Enzyme-Linked Immunosorbent Assay; Factor VII; Factor XII; Fatty Acids, Nonesterified; Female; Fibrinogen; Follow-Up Studies; Hemostasis; Humans; Hydroxymethylglutaryl CoA Reductases; Hypercholesterolemia; Hypolipidemic Agents; Lipoproteins; Lovastatin; Male; Middle Aged; Prospective Studies; Prothrombin; Risk Factors; Simvastatin; Single-Blind Method	1997
No influence of simvastatin treatment on platelet function in vivo in patients with hypercholesterolemia. Arteriosclerosis, thrombosis, and vascular biology, 1997, Volume: 17, Issue:2 Topics: Blood Platelets; Cross-Over Studies; Double-Blind Method; Enzyme Inhibitors; Humans; Hypercholesterolemia; Lipids; Lovastatin; Male; Platelet Aggregation; Rest; Simvastatin; Stress, Psychological; Thromboxane B2; Thyroglobulin	1997
The role of triglyceride-rich lipoprotein families in the progression of atherosclerotic lesions as determined by sequential coronary angiography from a controlled clinical trial. Arteriosclerosis, thrombosis, and vascular biology, 1997, Volume: 17, Issue:4 Topics: Adult; Aged; Apolipoproteins; Arteriosclerosis; Coronary Angiography; Female; Humans; Hypercholesterolemia; Lipoproteins; Lovastatin; Male; Middle Aged; Odds Ratio; Time Factors; Triglycerides	1997
[Long term treatment of moderate to severe hypercholesterolemia with low dose statin. Comparison of simvastatin and pravastatin]. Recenti progressi in medicina, 1996, Volume: 87, Issue:11 Topics: Aged; Anticholesteremic Agents; Female; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lovastatin; Male; Middle Aged; Pravastatin; Severity of Illness Index; Simvastatin; Time Factors	1996
Intermediate-density lipoproteins and progression of carotid arterial wall intima-media thickness. Circulation, 1997, Apr-15, Volume: 95, Issue:8 Topics: Adult; Aged; Arteriosclerosis; Carotid Artery, Common; Carotid Stenosis; Cholesterol, Dietary; Cholesterol, HDL; Cholesterol, LDL; Disease Progression; Double-Blind Method; Endothelium, Vascular; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Lipoproteins; Lipoproteins, IDL; Lipoproteins, VLDL; Lovastatin; Male; Middle Aged; Risk Factors; Triglycerides; Ultrasonography	1997
Effect of simvastatin therapy on cell membrane cholesterol content and membrane function as assessed by polymorphonuclear cell NADPH oxidase activity. Annals of clinical biochemistry, 1997, Volume: 34 ( Pt 3) Topics: Adult; Anticholesteremic Agents; Cell Membrane; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Membrane Fluidity; Membrane Lipids; Middle Aged; NADPH Oxidases; Neutrophils; Simvastatin	1997
Comparison of one-year efficacy and safety of atorvastatin versus lovastatin in primary hypercholesterolemia. Atorvastatin Study Group I. The American journal of cardiology, 1997, Jun-01, Volume: 79, Issue:11 Topics: Analysis of Variance; Anticholesteremic Agents; Atorvastatin; Cholesterol; Double-Blind Method; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Pyrroles; Treatment Outcome	1997
A multicenter, double-blind, one-year study comparing safety and efficacy of atorvastatin versus simvastatin in patients with hypercholesterolemia. The American journal of cardiology, 1997, Jul-01, Volume: 80, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Apolipoproteins B; Arthralgia; Atorvastatin; Cholesterol; Cholesterol, Dietary; Cholesterol, LDL; Double-Blind Method; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Hyperhidrosis; Hyperlipidemias; Lovastatin; Male; Middle Aged; Patient Education as Topic; Pyrroles; Simvastatin; Triglycerides	1997
Short-term safety and efficacy of low-dose simvastatin in elderly patients with hypertensive hypercholesterolemia and fasting hyperinsulinemia. Journal of clinical pharmacology, 1997, Volume: 37, Issue:6 Topics: Aged; Anticholesteremic Agents; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperinsulinism; Hypertension; Lovastatin; Male; Patient Compliance; Simvastatin	1997
The efficacy of lovastatin in lowering cholesterol in African Americans with primary hypercholesterolemia. The American journal of medicine, 1997, Volume: 102, Issue:4 Topics: Anticholesteremic Agents; Black People; Cholesterol; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged	1997
Enhanced oxidizability of ubiquinol and alpha-tocopherol during lovastatin treatment. FEBS letters, 1997, Jun-30, Volume: 410, Issue:2-3 Topics: Adult; Aged; Anticholesteremic Agents; Antioxidants; Apolipoproteins A; Apolipoproteins B; Cholesterol; Cholesterol, LDL; Copper; Coronary Disease; Cross-Over Studies; Double-Blind Method; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Oxidation-Reduction; Triglycerides; Ubiquinone; Vitamin E	1997
Dose-related decrease of serum coenzyme Q10 during treatment with HMG-CoA reductase inhibitors. Molecular aspects of medicine, 1997, Volume: 18 Suppl Topics: Adult; Aged; Antioxidants; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Coenzymes; Coronary Disease; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Oxidation-Reduction; Pravastatin; Risk Factors; Ubiquinone	1997
Crossover trial of simvastatin versus pravastatin in patients with primary hypercholesterolemia. Journal of cardiovascular pharmacology, 1997, Volume: 30, Issue:1 Topics: Adult; Aged; Anticholesteremic Agents; Apolipoproteins; Cholesterol; Cross-Over Studies; Enzyme Inhibitors; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Pravastatin; Simvastatin	1997
Estrogen and progestin compared with simvastatin for hypercholesterolemia in postmenopausal women. The New England journal of medicine, 1997, Aug-28, Volume: 337, Issue:9 Topics: Aged; Anticholesteremic Agents; Cholesterol; Cross-Over Studies; Drug Therapy, Combination; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Humans; Hypercholesterolemia; Linear Models; Lovastatin; Medroxyprogesterone; Middle Aged; Postmenopause; Simvastatin; Triglycerides	1997
[The effect of hypolipidemia treatment on the function of kidney transplanted from cadavers]. Polskie Archiwum Medycyny Wewnetrznej, 1997, Volume: 97, Issue:2 Topics: Adult; Anticholesteremic Agents; Azathioprine; Cadaver; Cholesterol; Cholesterol, LDL; Creatinine; Cyclosporine; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Kidney; Kidney Transplantation; Lovastatin; Male; Middle Aged; Prednisone; Prospective Studies; Triglycerides	1997
Effects of lovastatin on the immune system. The American journal of cardiology, 1997, Nov-15, Volume: 80, Issue:10 Topics: Adult; Anticholesteremic Agents; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Immune System; Lovastatin; Middle Aged	1997
[The effect of hypolipemic treatment on the pharmacokinetics of propranolol]. Annales Academiae Medicae Stetinensis, 1997, Volume: 43 Topics: Administration, Oral; Anticholesteremic Agents; Bezafibrate; Chromatography, High Pressure Liquid; Drug Interactions; Female; Humans; Hydroxylation; Hypercholesterolemia; Hyperlipidemias; Hypertriglyceridemia; Hypolipidemic Agents; Lovastatin; Male; Phenotype; Propranolol; Triglycerides	1997
[Gemfibrozil reduces elevated lipoprotein (a) levels in hypercholesterolemic patients]. Arquivos brasileiros de cardiologia, 1997, Volume: 68, Issue:4 Topics: Analysis of Variance; Anticholesteremic Agents; Chi-Square Distribution; Female; Gemfibrozil; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lipoprotein(a); Lovastatin; Male; Middle Aged	1997
Comparative dose efficacy study of atorvastatin versus simvastatin, pravastatin, lovastatin, and fluvastatin in patients with hypercholesterolemia (the CURVES study) The American journal of cardiology, 1998, Mar-01, Volume: 81, Issue:5 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Fatty Acids, Monounsaturated; Female; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Male; Middle Aged; Pravastatin; Pyrroles; Simvastatin; Treatment Outcome	1998
Ubiquinone supplementation during lovastatin treatment: effect on LDL oxidation ex vivo. Journal of lipid research, 1998, Volume: 39, Issue:7 Topics: Analysis of Variance; Anticholesteremic Agents; Antioxidants; Apolipoprotein A-I; Apolipoproteins B; Cholesterol; Copper Sulfate; Coronary Disease; Cross-Over Studies; Diet; Double-Blind Method; Humans; Hypercholesterolemia; Lipoproteins, HDL; Lipoproteins, LDL; Lovastatin; Male; Middle Aged; Oxidation-Reduction; Oxidative Stress; Triglycerides; Ubiquinone	1998
Clinical efficacy of cerivastatin: phase IIa dose-ranging and dose-scheduling studies. The American journal of cardiology, 1998, Aug-27, Volume: 82, Issue:4B Topics: Apolipoproteins B; Cholesterol, HDL; Cholesterol, LDL; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Pyridines; Safety; Simvastatin; Treatment Outcome; Triglycerides	1998
Clinical efficacy and safety of cerivastatin: summary of pivotal phase IIb/III studies. The American journal of cardiology, 1998, Aug-27, Volume: 82, Issue:4B Topics: Adolescent; Adult; Aged; Apolipoprotein A-I; Cholesterol, HDL; Cholesterol, LDL; Dose-Response Relationship, Drug; Double-Blind Method; Drug Evaluation; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Pravastatin; Pyridines; Safety; Simvastatin; Treatment Outcome	1998
Comparison of the effects of pravastatin and lovastatin on sleep disturbance in hypercholesterolemic subjects. Sleep, 1999, Feb-01, Volume: 22, Issue:1 Topics: Adult; Cross-Over Studies; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Pravastatin; Sleep Wake Disorders; Sleep, REM	1999
Comparative efficacy and tolerability of low-dose pravastatin versus lovastatin in patients with hypercholesterolemia. American heart journal, 1999, Volume: 137, Issue:3 Topics: Aged; Alkaline Phosphatase; Anticholesteremic Agents; Aspartate Aminotransferases; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Creatine Kinase; Cross-Over Studies; Drug Costs; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Incidence; L-Lactate Dehydrogenase; Liver; Lovastatin; Male; Middle Aged; Pravastatin; Triglycerides	1999
When the vessel is bad, lowering cholesterol may save the ship. HMO practice, 1997, Volume: 11, Issue:2 Topics: Adult; Aged; Anticholesteremic Agents; Coronary Disease; Denmark; Evidence-Based Medicine; Female; Humans; Hypercholesterolemia; Iceland; Lovastatin; Male; Middle Aged; Mortality; Norway; Sweden; Treatment Outcome	1997
The cost of reaching National Cholesterol Education Program (NCEP) goals in hypercholesterolaemic patients. A comparison of atorvastatin, simvastatin, lovastatin and fluvastatin. PharmacoEconomics, 1998, Volume: 14, Issue:1 Topics: Aged; Anticholesteremic Agents; Atorvastatin; Cost-Benefit Analysis; Fatty Acids, Monounsaturated; Female; Fluvastatin; Health Policy; Heptanoic Acids; Humans; Hypercholesterolemia; Indoles; Lovastatin; Male; Middle Aged; Pyrroles; Simvastatin; United States	1998
The effect of the apolipoprotein E phenotype on cholesteryl ester transfer protein activity, plasma lipids and apolipoprotein A I levels in hypercholesterolaemic patients on colestipol and lovastatin treatment. European journal of clinical pharmacology, 1999, Volume: 54, Issue:12 Topics: Adult; Apolipoproteins E; Carrier Proteins; Cholesterol; Cholesterol Ester Transfer Proteins; Colestipol; Female; Glycoproteins; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lovastatin; Male; Middle Aged; Phenotype; Triglycerides	1999
Additional reduction in blood pressure after cholesterol-lowering treatment by statins (lovastatin or pravastatin) in hypercholesterolemic patients using angiotensin-converting enzyme inhibitors (enalapril or lisinopril). The American journal of cardiology, 1999, May-15, Volume: 83, Issue:10 Topics: Angiotensin-Converting Enzyme Inhibitors; Anticholesteremic Agents; Blood Pressure; Drug Interactions; Enalapril; Female; Heart Rate; Humans; Hypercholesterolemia; Hypertension; Lisinopril; Lovastatin; Male; Middle Aged; Pravastatin	1999
Effect of cholesterol lowering treatment on positive exercise tests in patients with hypercholesterolaemia and normal coronary angiograms. Heart (British Cardiac Society), 1999, Volume: 82, Issue:6 Topics: Adult; Analysis of Variance; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Combined Modality Therapy; Coronary Angiography; Diet, Fat-Restricted; Exercise Test; Exercise Tolerance; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lovastatin; Male; Middle Aged; Simvastatin	1999
Effects of lovastatin on cognitive function and psychological well-being. The American journal of medicine, 2000, Volume: 108, Issue:7 Topics: Adult; Affect; Anger; Anticholesteremic Agents; Attention; Cognition; Double-Blind Method; Female; Hostility; Humans; Hypercholesterolemia; Lipids; Lovastatin; Male; Memory; Middle Aged; Psychomotor Performance; Quality of Life; Thinking; Treatment Outcome	2000
Comparative study of the efficacy and tolerability of policosanol and lovastatin in patients with hypercholesterolemia and noninsulin dependent diabetes mellitus. International journal of clinical pharmacology research, 1999, Volume: 19, Issue:4 Topics: Anticholesteremic Agents; Blood Pressure; Diabetes Mellitus, Type 2; Double-Blind Method; Fatty Alcohols; Female; Headache; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Risk Factors; Treatment Outcome	1999
Application of the National Cholesterol Education Program and joint European treatment criteria and clinical benefit in the Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS). European heart journal, 2000, Volume: 21, Issue:19 Topics: Aged; Anticholesteremic Agents; Cholesterol, LDL; Coronary Artery Disease; Female; Humans; Hypercholesterolemia; Incidence; Lovastatin; Male; Middle Aged; Military Personnel; Patient Education as Topic; Practice Guidelines as Topic; Program Evaluation; Texas	2000
Reduction of LDL cholesterol in patients with primary hypercholesterolemia by SCH 48461: results of a multicenter dose-ranging study. Journal of clinical pharmacology, 2001, Volume: 41, Issue:1 Topics: Anticholesteremic Agents; Apolipoprotein A-I; Azetidines; Cholesterol, HDL; Cholesterol, LDL; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Placebos; Triglycerides	2001
Comparative efficacy study of atorvastatin vs simvastatin, pravastatin, lovastatin and placebo in type 2 diabetic patients with hypercholesterolaemia. Diabetes, obesity & metabolism, 2000, Volume: 2, Issue:6 Topics: Aged; Anticholesteremic Agents; Atorvastatin; Blood Glucose; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Insulin; Lovastatin; Male; Middle Aged; Placebos; Pravastatin; Pyrroles; Simvastatin; Triglycerides	2000
Statin therapy and plasma C-reactive protein levels in primary prevention. Cardiovascular drugs and therapy, 2000, Volume: 14, Issue:6 Topics: Aged; Anticholesteremic Agents; Arteriosclerosis; Biomarkers; C-Reactive Protein; Cholesterol; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Pravastatin	2000
Low-dose combination therapy with colesevelam hydrochloride and lovastatin effectively decreases low-density lipoprotein cholesterol in patients with primary hypercholesterolemia. Clinical cardiology, 2001, Volume: 24, Issue:6 Topics: Allylamine; Analysis of Variance; Anticholesteremic Agents; Cholesterol, LDL; Colesevelam Hydrochloride; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Treatment Outcome	2001
Apolipoprotein E genotype affects plasma lipid response to atorvastatin in a gender specific manner. Atherosclerosis, 2001, Volume: 158, Issue:1 Topics: Anticholesteremic Agents; Apolipoproteins E; Atorvastatin; Double-Blind Method; Female; Genotype; Heptanoic Acids; Heterozygote; Homozygote; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lipoproteins; Lovastatin; Male; Middle Aged; Pyrroles; Sex Factors	2001
Effects of lovastatin and pravastatin on cognitive function in military aircrew. Aviation, space, and environmental medicine, 2001, Volume: 72, Issue:9 Topics: Adult; Anticholesteremic Agents; Cognition; Double-Blind Method; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Military Personnel; Neuropsychological Tests; Pravastatin; Psychomotor Performance	2001
Dose response, safety, and efficacy of an extended-release formulation of lovastatin in adults with hypercholesterolemia. The American journal of cardiology, 2002, Jan-15, Volume: 89, Issue:2 Topics: Adult; Aged; Anticholesteremic Agents; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Treatment Outcome	2002
A multiple-dose pharmacodynamic, safety, and pharmacokinetic comparison of extended- and immediate-release formulations of lovastatin. Clinical therapeutics, 2002, Volume: 24, Issue:1 Topics: Adult; Aged; Anticholesteremic Agents; Area Under Curve; Cholesterol; Delayed-Action Preparations; Female; Humans; Hydroxymethylglutaryl CoA Reductases; Hypercholesterolemia; Liver Function Tests; Lovastatin; Male; Middle Aged; Patient Compliance; Single-Blind Method	2002
Pharmacological concentrations of the HMG-CoA reductase inhibitor lovastatin decrease the formation of the Alzheimer beta-amyloid peptide in vitro and in patients. Frontiers in bioscience : a journal and virtual library, 2002, Apr-01, Volume: 7 Topics: Adult; Aged; Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Line; CHO Cells; Cholesterol; Cricetinae; Dogs; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Peptide Fragments	2002
Lipid-lowering long-term effects of six different statins in hypercholesterolemic renal transplant patients under cyclosporine immunosuppression. Transplantation proceedings, 2002, Volume: 34, Issue:1 Topics: Adult; Anticholesteremic Agents; Cholesterol; Cyclosporine; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Transplantation; Lipoproteins; Lovastatin; Male; Middle Aged; Time Factors; Triglycerides	2002
Lathosterol and other noncholesterol sterols during treatment of hypercholesterolemia with lovastatin alone and with cholestyramine or guar gum. Arteriosclerosis and thrombosis : a journal of vascular biology, 1992, Volume: 12, Issue:7 Topics: Adult; Cholesterol; Cholestyramine Resin; Dietary Fiber; Female; Galactans; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lovastatin; Male; Mannans; Middle Aged; Plant Gums; Sterols	1992
A randomized placebo controlled trial on the effects of simvastatin, a HMG-CoA reductase inhibitor, on blood lipids and fibrinolytic parameters. Acta clinica Belgica, 1992, Volume: 47, Issue:2 Topics: Adult; Aged; Anticholesteremic Agents; Apolipoproteins B; Blood Coagulation Tests; Cholesterol; Double-Blind Method; Humans; Hydroxymethylglutaryl-CoA Synthase; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Plasminogen Inactivators; Simvastatin	1992
[Effects of lovastatin therapy on the level of low density lipoproteins and atherogenic potential of serum in patients with ischemic heart disease and hypercholesterolemia]. Kardiologiia, 1992, Volume: 32, Issue:6 Topics: Animals; Antigen-Antibody Complex; Cells, Cultured; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Humans; Hypercholesterolemia; Lipoproteins, LDL; Lovastatin; Macrophages; Mice	1992
Successful management of primary hypercholesterolaemia with simvastatin and low-dose colestipol. The Medical journal of Australia, 1992, Oct-05, Volume: 157, Issue:7 Topics: Anticholesteremic Agents; Apolipoproteins B; Cholesterol; Cholesterol, LDL; Colestipol; Double-Blind Method; Drug Therapy, Combination; Humans; Hypercholesterolemia; Lipoproteins, HDL; Lovastatin; Simvastatin; Treatment Outcome; Triglycerides	1992
Efficacy and tolerability of simvastatin and pravastatin in patients with primary hypercholesterolemia (multicountry comparative study). The European Study Group. The American journal of cardiology, 1992, Nov-15, Volume: 70, Issue:15 Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Pravastatin; Simvastatin; Triglycerides	1992
Changes in Lp(a) lipoprotein levels during the treatment of hypercholesterolaemia with simvastatin. European journal of clinical pharmacology, 1992, Volume: 43, Issue:4 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoprotein(a); Lovastatin; Male; Middle Aged; Risk Factors; Simvastatin	1992
Simvastatin in non-insulin-dependent diabetic patients with hypercholesterolaemia. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1992, Volume: 82, Issue:6 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Cholesterol, HDL; Diabetes Mellitus, Type 2; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides	1992
Treatment of hypercholesterolemia and prevention of coronary artery disease after heart transplantation by combination of low-dose simvastatin and HELP-LDL-apheresis. Transplantation proceedings, 1992, Volume: 24, Issue:6 Topics: Adult; Anticholesteremic Agents; Blood Component Removal; Chemical Precipitation; Cholesterol, LDL; Combined Modality Therapy; Coronary Disease; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Heart Transplantation; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Postoperative Complications; Simvastatin	1992
[Lovastatin in primary hypercholesterolemia. A Norwegian multicenter study]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1992, Nov-30, Volume: 112, Issue:29 Topics: Adult; Aged; Cholesterol; Cholestyramine Resin; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Triglycerides	1992
Lens opacity in patients with hypercholesterolemia and ischaemic heart disease. Electronic lens opacity measurements. Documenta ophthalmologica. Advances in ophthalmology, 1992, Volume: 80, Issue:4 Topics: Adult; Aged; Cataract; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Myocardial Ischemia; Ophthalmology; Reproducibility of Results; Simvastatin	1992
Comparison of gemfibrozil and lovastatin in patients with high low-density lipoprotein and low high-density lipoprotein cholesterol levels. Archives of internal medicine, 1992, Volume: 152, Issue:9 Topics: Cholesterol, Dietary; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Female; Gemfibrozil; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged	1992
Expanded Clinical Evaluation of Lovastatin (EXCEL) study results. Effect of patient characteristics on lovastatin-induced changes in plasma concentrations of lipids and lipoproteins. Circulation, 1992, Volume: 85, Issue:4 Topics: Cholesterol, HDL; Cholesterol, LDL; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypercholesterolemia; Linear Models; Lovastatin; Male; Middle Aged; Triglycerides	1992
The cost of simvastatin therapy in treatment of hypercholesterolaemia in a hospital lipid clinic. The Medical journal of Australia, 1992, Apr-06, Volume: 156, Issue:7 Topics: Anticholesteremic Agents; Drug Costs; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lovastatin; Middle Aged; Simvastatin	1992
Effect of simvastatin in patients with type I (insulin-dependent) diabetes mellitus and hypercholesterolemia. Acta endocrinologica, 1992, Volume: 126, Issue:3 Topics: Adult; Anticholesteremic Agents; Blood Glucose; Diabetes Mellitus, Type 1; Female; Hormones; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin	1992
A multicenter comparison of the effects of simvastatin and fenofibrate therapy in severe primary hypercholesterolemia, with particular emphasis on lipoproteins defined by their apolipoprotein composition. Metabolism: clinical and experimental, 1992, Volume: 41, Issue:5 Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Apolipoproteins; Cholesterol; Female; Fenofibrate; Humans; Hypercholesterolemia; In Vitro Techniques; Lipoproteins; Lovastatin; Male; Middle Aged; Simvastatin	1992
Effect of simvastatin, ursodeoxycholic acid and simvastatin plus ursodeoxycholic acid on biliary lipid secretion and cholic acid kinetics in nonfamilial hypercholesterolemia. Hepatology (Baltimore, Md.), 1992, Volume: 15, Issue:6 Topics: Adult; Aged; Anticholesteremic Agents; Bile; Cholesterol; Cholic Acid; Cholic Acids; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Kinetics; Lipid Metabolism; Liver; Lovastatin; Male; Middle Aged; Simvastatin; Ursodeoxycholic Acid	1992
Is fat restriction needed with HMGCoA reductase inhibitor treatment? Atherosclerosis, 1992, Volume: 93, Issue:1-2 Topics: Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Combined Modality Therapy; Dietary Fats; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides	1992
Comparison between lovastatin and cholestyramine in the treatment of moderate to severe primary hypercholesterolaemia. Annals of medicine, 1992, Volume: 24, Issue:2 Topics: Adult; Aged; Apolipoprotein A-I; Apolipoproteins B; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Female; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lovastatin; Male; Middle Aged; Triglycerides	1992
Lovastatin alters blood rheology in primary hyperlipoproteinemia: dependence on lipoprotein(a)? Journal of clinical pharmacology, 1992, Volume: 32, Issue:6 Topics: Bezafibrate; Blood Viscosity; Delayed-Action Preparations; Erythrocyte Aggregation; Erythrocyte Deformability; Female; Humans; Hypercholesterolemia; Hyperlipoproteinemias; Lipids; Lipoproteins; Lovastatin; Male; Middle Aged; Rheology; Single-Blind Method	1992
Lipid control with low-dosage simvastatin in patients with moderate hypercholesterolaemia. An Italian multicentre double-blind placebo-controlled study. European heart journal, 1992, Volume: 13 Suppl B Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol, HDL; Cholesterol, LDL; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Italy; Lipids; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides	1992
Worldwide experience with simvastatin/lovastatin. European heart journal, 1992, Volume: 13 Suppl B Topics: Anticholesteremic Agents; Chemical and Drug Induced Liver Injury; Cholesterol, LDL; Coronary Artery Disease; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Long-Term Care; Lovastatin; Rhabdomyolysis; Simvastatin	1992
[Effect of HMG-CoA reductase inhibitors on the erythrocyte membrane]. Bollettino della Societa italiana di biologia sperimentale, 1991, Volume: 67, Issue:2 Topics: Cholesterol; Erythrocyte Membrane; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lovastatin; Male; Membrane Fluidity; Membrane Lipids; Middle Aged; Simvastatin; Sodium-Potassium-Exchanging ATPase	1991
Lack of hypotension with lovastatin and pravastatin. Lancet (London, England), 1991, Nov-23, Volume: 338, Issue:8778 Topics: Adult; Aged; Double-Blind Method; Humans; Hypercholesterolemia; Hypotension, Orthostatic; Lovastatin; Male; Middle Aged; Pravastatin	1991
Combination therapy with lovastatin and guar gum versus lovastatin and cholestyramine in treatment of hypercholesterolemia. Journal of cardiovascular pharmacology, 1991, Volume: 18, Issue:4 Topics: Adult; Aged; Apolipoprotein A-I; Apolipoproteins B; Blood Pressure; Body Weight; Cholestyramine Resin; Double-Blind Method; Drug Therapy, Combination; Female; Galactans; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lipids; Lovastatin; Male; Mannans; Middle Aged; Plant Gums	1991
A comparison between lovastatin and gemfibrozil in the treatment of primary hypercholesterolemia. The American journal of cardiology, 1992, Jan-01, Volume: 69, Issue:1 Topics: Adult; Aged; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Female; Gemfibrozil; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Multivariate Analysis; Research Design; Triglycerides	1992
Low-dose simvastatin for the treatment of hypercholesterolaemia in recipients of cardiac transplantation. International journal of cardiology, 1991, Volume: 33, Issue:2 Topics: Adult; Anticholesteremic Agents; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Female; Heart Transplantation; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Postoperative Care; Simvastatin; Triglycerides	1991
[Comparison about the efficacy and tolerability between simvastatin and bezafibrate in the treatment of hypercholesterolemia]. Annales de medecine interne, 1991, Volume: 142, Issue:7 Topics: Adult; Anticholesteremic Agents; Bezafibrate; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin	1991
Significant increase of high-density lipoprotein2-cholesterol under prolonged simvastatin treatment. Atherosclerosis, 1991, Volume: 91 Suppl Topics: Aged; Anticholesteremic Agents; Apolipoproteins; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Female; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides	1991
Long-term efficacy and safety of simvastatin alone and in combination therapy in treatment of hypercholesterolaemia. Atherosclerosis, 1991, Volume: 91 Suppl Topics: Adult; Aged; Anticholesteremic Agents; Cholestyramine Resin; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lens, Crystalline; Lipids; Liver; Lovastatin; Male; Middle Aged; Simvastatin	1991
Lipoprotein particle analysis comparing simvastatin and fenofibrate. Atherosclerosis, 1991, Volume: 91 Suppl Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Apolipoprotein A-I; Apolipoprotein A-II; Apolipoproteins; Apolipoproteins B; Double-Blind Method; Fenofibrate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoproteins; Lovastatin; Middle Aged; Simvastatin	1991
A multicenter double-blind study comparing lovastatin and gemfibrozil in the treatment of primary hypercholesterolemia. Atherosclerosis, 1991, Volume: 91 Suppl Topics: Adult; Aged; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Female; Gemfibrozil; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Triglycerides	1991
[Comparison between lovastatin and gemfibrozil in treatment of primary hyperlipidemias]. Arquivos brasileiros de cardiologia, 1991, Volume: 56, Issue:5 Topics: Adult; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Female; Gemfibrozil; Humans; Hypercholesterolemia; Hyperlipidemias; Hypertriglyceridemia; Lovastatin; Male; Middle Aged; Triglycerides	1991
[Effects of lovastatin and probucol on lipoprotein fractions in patients with hypercholesterolemia. A Brazilian multicenter study]. Arquivos brasileiros de cardiologia, 1991, Volume: 57, Issue:3 Topics: Analysis of Variance; Brazil; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Probucol; Triglycerides	1991
[Therapy of hypercholesterolemia and hypertriglyceridemia. Comparison of hypolipemic effects of lovastatin and gemfibrozil]. La Clinica terapeutica, 1991, Jan-15, Volume: 136, Issue:1 Topics: Aged; Apolipoproteins B; Cholesterol; Female; Gemfibrozil; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Phospholipids; Triglycerides	1991
Expanded clinical evaluation of lovastatin (EXCEL) study results: IV. Additional perspectives on the tolerability of lovastatin. The American journal of medicine, 1991, Jul-31, Volume: 91, Issue:1B Topics: Alanine Transaminase; Aspartate Aminotransferases; Combined Modality Therapy; Creatine Kinase; Dietary Fats; Double-Blind Method; Drug Eruptions; Female; Gastrointestinal Diseases; Humans; Hypercholesterolemia; Incidence; Lovastatin; Male; Middle Aged; Muscular Diseases; Nervous System Diseases	1991
[Effects and side effects of a 1-year treatment of primary hypercholesterolemia with simvastatin]. Schweizerische medizinische Wochenschrift, 1991, Jun-29, Volume: 121, Issue:26 Topics: Anticholesteremic Agents; Cholesterol; Creatine Kinase; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipoproteinemia Type II; Liver; Lovastatin; Male; Simvastatin; Single-Blind Method; Transaminases; Triglycerides	1991
The effect of lovastatin treatment on low-density lipoprotein hydrated density distribution and composition in patients with intermittent claudication and primary hypercholesterolemia. Metabolism: clinical and experimental, 1991, Volume: 40, Issue:6 Topics: Apolipoproteins; Apolipoproteins B; Arteriosclerosis; Cholesterol; Cholesterol Esters; Female; Humans; Hypercholesterolemia; Intermittent Claudication; Lipoproteins; Lipoproteins, LDL; Lovastatin; Male; Phospholipids; Triglycerides	1991
Expanded clinical evaluation of lovastatin (EXCEL) study results: III. Efficacy in modifying lipoproteins and implications for managing patients with moderate hypercholesterolemia. The American journal of medicine, 1991, Jul-31, Volume: 91, Issue:1B Topics: Cholesterol, HDL; Cholesterol, LDL; Combined Modality Therapy; Dietary Fats; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lipoproteins; Lovastatin; Male; Middle Aged; Triglycerides	1991
Lovastatin therapy in hypercholesterolemia: effect on fibrinogen, hemorrheologic parameters, platelet activity, and red blood cell morphology. Journal of clinical pharmacology, 1991, Volume: 31, Issue:6 Topics: Adolescent; Adult; Aged; Blood Viscosity; Cholesterol, HDL; Cholesterol, LDL; Erythrocyte Deformability; Fibrinogen; Humans; Hypercholesterolemia; Lovastatin; Middle Aged; Platelet Aggregation; Platelet Count; Rheology	1991
Treatment of primary hypercholesterolaemia with simvastatin. New Zealand multicentre evaluation. The Medical journal of Australia, 1991, Oct-07, Volume: 155, Issue:7 Topics: Adult; Aged; Anticholesteremic Agents; Bezafibrate; Cholesterol; Cholesterol, LDL; Cohort Studies; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; New Zealand; Simvastatin	1991
Effect of apolipoprotein E polymorphism and XbaI polymorphism of apolipoprotein B on response to lovastatin treatment in familial and non-familial hypercholesterolaemia. Journal of internal medicine, 1991, Volume: 230, Issue:5 Topics: Adult; Aged; Apolipoproteins B; Apolipoproteins E; Deoxyribonucleases, Type II Site-Specific; Female; Genotype; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lovastatin; Male; Middle Aged; Phenotype; Polymorphism, Genetic	1991
Long-term safety and efficacy profile of simvastatin. The American journal of cardiology, 1991, Nov-01, Volume: 68, Issue:11 Topics: Aged; Anticholesteremic Agents; Cataract; Coronary Disease; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Liver; Lovastatin; Male; Middle Aged; Muscles; Simvastatin	1991
Comparative effects of two HMG-CoA reductase inhibitors (lovastatin and pravastatin) on serum lipids and lipoproteins. International journal of tissue reactions, 1991, Volume: 13, Issue:2 Topics: Cholesterol; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lipoproteins; Lovastatin; Middle Aged; Pravastatin	1991
Effect of simvastatin and fenofibrate on the fatty acid composition of hypercholesterolaemic patients. British journal of clinical pharmacology, 1991, Volume: 32, Issue:4 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol Esters; Double-Blind Method; Fatty Acids; Female; Fenofibrate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoproteins; Lovastatin; Male; Middle Aged; Phospholipids; Simvastatin; Triglycerides	1991
Expanded Clinical Evaluation of Lovastatin (EXCEL) study results. I. Efficacy in modifying plasma lipoproteins and adverse event profile in 8245 patients with moderate hypercholesterolemia. Archives of internal medicine, 1991, Volume: 151, Issue:1 Topics: Adult; Aged; Cholesterol, HDL; Cholesterol, LDL; Creatine Kinase; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lipoproteins; Liver Function Tests; Lovastatin; Male; Middle Aged; Muscular Diseases; Patient Compliance; Triglycerides	1991
Lovastatin efficacy in reducing low-density lipoprotein cholesterol levels on high- vs low-fat diets. JAMA, 1991, Feb-27, Volume: 265, Issue:8 Topics: Apolipoproteins; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Combined Modality Therapy; Dietary Fats; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Multivariate Analysis; Retrospective Studies	1991
Expanded clinical evaluation of lovastatin (EXCEL) study results. II. Assessment of the human lens after 48 weeks of treatment with lovastatin. The American journal of cardiology, 1991, Mar-01, Volume: 67, Issue:6 Topics: Adolescent; Adult; Aged; Cataract; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lens, Crystalline; Lovastatin; Male; Middle Aged; Visual Acuity	1991
Hemorheologic and coagulative pattern in hypercholesterolemic subjects treated with lipid-lowering drugs. Angiology, 1991, Volume: 42, Issue:2 Topics: Adult; Aged; Anticholesteremic Agents; Bezafibrate; Blood Coagulation; Blood Coagulation Factors; Cholesterol; Female; Hemostasis; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides	1991
[Lovastatin efficacy and tolerance in primary hypercholesterolemia. The German Lovastatin Study Group]. Deutsche medizinische Wochenschrift (1946), 1991, Jun-07, Volume: 116, Issue:23 Topics: Adult; Clinical Trials as Topic; Drug Tolerance; Female; Humans; Hypercholesterolemia; Lipids; Lipoproteins; Lovastatin; Male; Middle Aged; Tablets	1991
[Treatment of hypercholesterolemic patients of different age with simvastatin: 1-year study]. Recenti progressi in medicina, 1991, Volume: 82, Issue:3 Topics: Adult; Age Factors; Aged; Anticholesteremic Agents; Cholesterol; Cholesterol, LDL; Cholestyramine Resin; Drug Therapy, Combination; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Middle Aged; Simvastatin; Time Factors	1991
A 6-month trial of simvastatin (HMG-CoA reductase inhibitor) in the treatment of hypercholesterolaemia. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1991, Jun-01, Volume: 79, Issue:11 Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Cholesterol; Cholesterol, LDL; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin	1991
Effects of HMG-CoA reductase inhibitors in hypercholesterolemic patients on hemodialysis. Kidney international, 1991, Volume: 39, Issue:4 Topics: Adult; Aged; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertriglyceridemia; Kidney Failure, Chronic; Lipids; Lipoproteins; Lovastatin; Male; Middle Aged; Renal Dialysis; Simvastatin	1991
Simvastatin in severe hypercholesterolaemia: a placebo controlled trial. British journal of clinical pharmacology, 1991, Volume: 31, Issue:3 Topics: Adult; Aged; Anticholesteremic Agents; Apolipoproteins B; Blood Pressure; Blood Viscosity; Cholesterol; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl CoA Reductases; Hypercholesterolemia; Leukocytes; Lipids; Liver; Lovastatin; Male; Middle Aged; Simvastatin; Transaminases; Triglycerides	1991
[The comparative treatment with lovastatin and bezafibrate of primary hypercholesterolemia. A randomized and double-blind trial]. Revista espanola de cardiologia, 1991, Volume: 44, Issue:4 Topics: Apolipoproteins A; Apolipoproteins B; Bezafibrate; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Humans; Hypercholesterolemia; Lovastatin; Spain; Triglycerides	1991
Lovastatin versus bezafibrate: efficacy, tolerability, and effect on urinary mevalonate. Cardiology, 1990, Volume: 77 Suppl 4 Topics: Adult; Aged; Bezafibrate; Female; Humans; Hypercholesterolemia; Lipids; Lovastatin; Male; Mevalonic Acid; Middle Aged; Single-Blind Method	1990
Safety, tolerability, and efficacy of simvastatin and fenofibrate--a multicenter study. Simvastatin-Fenofibrate Study Group. Cardiology, 1990, Volume: 77 Suppl 4 Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Apolipoproteins; Cholesterol; Double-Blind Method; Female; Fenofibrate; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides	1990
Lens changes in matched normals and hyperlipidemic patients treated with simvastatin for 2 years. Acta ophthalmologica, 1990, Volume: 68, Issue:6 Topics: Adult; Aged; Cataract; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Lens, Crystalline; Lovastatin; Male; Middle Aged; Simvastatin; Vacuoles	1990
Pravastatin therapy in primary moderate hypercholesterolaemia: changes in metabolism of apolipoprotein B-containing lipoproteins. Journal of internal medicine, 1990, Volume: 227, Issue:2 Topics: Adult; Aged; Anticholesteremic Agents; Apolipoproteins B; Biological Transport; Cholesterol; Double-Blind Method; Heptanoic Acids; Humans; Hypercholesterolemia; Kinetics; Lipoproteins, LDL; Lovastatin; Middle Aged; Naphthalenes; Pravastatin	1990
Lovastatin treatment of hypercholesterolemia in renal transplant recipients. Transplantation, 1990, Volume: 49, Issue:1 Topics: Adolescent; Apolipoprotein A-I; Apolipoproteins A; Azathioprine; Child; Child, Preschool; Cholesterol, HDL; Cholesterol, LDL; Diet, Reducing; Humans; Hypercholesterolemia; Kidney Transplantation; Leukocyte Count; Lovastatin; Postoperative Complications	1990
HMG CoA reductase inhibitors as lipid-lowering agents: five years experience with lovastatin and an appraisal of simvastatin and pravastatin. The Quarterly journal of medicine, 1990, Volume: 74, Issue:274 Topics: Adult; Aged; Anticholesteremic Agents; Cholestyramine Resin; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Naphthalenes; Phenotype; Pravastatin; Simvastatin; Time Factors	1990
[Therapy of hypercholesterolemia and hypertriglyceridemia. Comparison of the lipid-lowering effect of simvastatin and tiadenol]. La Clinica terapeutica, 1990, Mar-15, Volume: 132, Issue:5 Topics: Aged; Anticholesteremic Agents; Clinical Trials as Topic; Double-Blind Method; Fatty Alcohols; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertriglyceridemia; Hypolipidemic Agents; Lovastatin; Male; Middle Aged; Simvastatin	1990
[Comparison of the lowering effect on blood cholesterol of clofibrate and simvastatin]. La Clinica terapeutica, 1990, May-15, Volume: 133, Issue:3 Topics: Aged; Anticholesteremic Agents; Clofibrate; Drug Evaluation; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin; Time Factors	1990
[The efficacy and tolerance of simvastatin and fenofibrate in primary hypercholesterolemia]. Presse medicale (Paris, France : 1983), 1990, Dec-08, Volume: 19, Issue:42 Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Apolipoproteins; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Drug Tolerance; Female; Fenofibrate; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Placebos; Simvastatin	1990
Hydroxymethylglutaryl coenzyme A reductase inhibitors as monotherapy in the treatment of hypercholesterolemia. The American journal of cardiology, 1990, Mar-20, Volume: 65, Issue:12 Topics: Bezafibrate; Cholestyramine Resin; Double-Blind Method; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lovastatin; Probucol; Randomized Controlled Trials as Topic; Simvastatin	1990
Cholesterol: myth or reality? Southern medical journal, 1990, Volume: 83, Issue:4 Topics: Age Factors; Aged; Cholesterol; Cholesterol, HDL; Clinical Trials as Topic; Coronary Disease; Evaluation Studies as Topic; Female; Follow-Up Studies; Health Education; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Reference Values; Risk Factors; Sex Factors	1990
Bezafibrate and simvastatin (MK-733) in the treatment of primary hypercholesterolaemia. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1990, May-19, Volume: 77, Issue:10 Topics: Adult; Aged; Anticholesteremic Agents; Bezafibrate; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Clinical Trials as Topic; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides	1990
Comparison of simvastatin and cholestyramine in the treatment of primary hypercholesterolaemia. The Medical journal of Australia, 1990, May-07, Volume: 152, Issue:9 Topics: Adult; Aged; Analysis of Variance; Anticholesteremic Agents; Australia; Cholesterol; Cholestyramine Resin; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Simvastatin; Triglycerides	1990
Efficacy and tolerability of lovastatin in a six-month study: analysis by gender, age and hypertensive status. The American journal of cardiology, 1990, Sep-18, Volume: 66, Issue:8 Topics: Adult; Age Factors; Aged; Aged, 80 and over; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Drug Evaluation; Female; Humans; Hypercholesterolemia; Hypertension; Lovastatin; Male; Middle Aged; Multicenter Studies as Topic; Sex Factors; Triglycerides	1990
Comparison of the effects of lovastatin and gemfibrozil on lipids and glucose control in non-insulin-dependent diabetes mellitus. The American journal of cardiology, 1990, Sep-18, Volume: 66, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Cholesterol; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Gemfibrozil; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Randomized Controlled Trials as Topic; Triglycerides	1990
A multicenter comparison of lovastatin and probucol for treatment of severe primary hypercholesterolemia. The Lovastatin Study Group IV. The American journal of cardiology, 1990, Sep-18, Volume: 66, Issue:8 Topics: Adult; Aged; Apolipoproteins; Cholesterol; Cholesterol, LDL; Double-Blind Method; Drug Evaluation; Female; Humans; Hypercholesterolemia; Hyperlipidemias; Lovastatin; Male; Middle Aged; Multicenter Studies as Topic; Phenols; Probucol; Randomized Controlled Trials as Topic; Triglycerides	1990
Expanded clinical evaluation of lovastatin (EXCEL) study: design and patient characteristics of a double-blind, placebo-controlled study in patients with moderate hypercholesterolemia. The American journal of cardiology, 1990, Sep-18, Volume: 66, Issue:8 Topics: Adult; Aged; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Placebos; Randomized Controlled Trials as Topic; Triglycerides	1990
Inhibitors of hydroxymethylglutaryl coenzyme A reductase for treating hypercholesterolaemia. BMJ (Clinical research ed.), 1990, Sep-29, Volume: 301, Issue:6753 Topics: Adult; Anticholesteremic Agents; Colestipol; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin; Sleep Wake Disorders	1990
Low-dose lovastatin safely lowers cholesterol after cardiac transplantation. Circulation, 1990, Volume: 82, Issue:5 Suppl Topics: Cholesterol; Female; Heart Transplantation; Humans; Hypercholesterolemia; Immunosuppressive Agents; Lovastatin; Male; Middle Aged	1990
Primary hypertriglyceridemia with borderline high cholesterol and elevated apolipoprotein B concentrations. Comparison of gemfibrozil vs lovastatin therapy. JAMA, 1990, Dec-05, Volume: 264, Issue:21 Topics: Adult; Aged; Apolipoproteins B; Cholesterol; Gemfibrozil; Humans; Hypercholesterolemia; Hypertriglyceridemia; Lipids; Lipoproteins; Lovastatin; Male; Middle Aged	1990
[Treatment of severe primary hypercholesterolemia with lovastatin (Mevacor). A new therapeutic principle]. Ugeskrift for laeger, 1990, Nov-05, Volume: 152, Issue:45 Topics: Adult; Aged; Denmark; Drug Evaluation; Female; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lovastatin; Male; Middle Aged	1990
[Simvastatin versus gemfibrozil in the treatment of primary hypercholesterolemia in hypertensive patients treated with hydrochlorothiazide]. Cardiologia (Rome, Italy), 1990, Volume: 35, Issue:4 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Female; Gemfibrozil; Humans; Hydrochlorothiazide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Lipoproteins, HDL; Lipoproteins, LDL; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides	1990
[Lovastatin: short-term treatment of hypercholesterolemia; multicenter clinical trial]. Medicina, 1990, Volume: 50, Issue:1 Topics: Adult; Aged; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Drug Administration Schedule; Drug Evaluation; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Triglycerides	1990
Simvastatin in the treatment of hypercholesterolaemia in patients with essential hypertension. Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1990, Volume: 8, Issue:1 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Dietary Fats, Unsaturated; Female; Humans; Hypercholesterolemia; Hypertension; Lovastatin; Male; Middle Aged; Random Allocation; Simvastatin	1990
The use of simvastatin, an HMG CoA reductase inhibitor, in older patients with hypercholesterolemia and atherosclerosis. Journal of the American Geriatrics Society, 1990, Volume: 38, Issue:1 Topics: Aged; Anticholesteremic Agents; Arteriosclerosis; Cataract; Cholesterol, HDL; Cholesterol, LDL; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Lovastatin; Male; Randomized Controlled Trials as Topic; Simvastatin	1990
Effects of simvastatin and cholestyramine in familial and nonfamilial hypercholesterolemia. Multicenter Group I. Archives of internal medicine, 1990, Volume: 150, Issue:2 Topics: Adult; Alanine Transaminase; Anticholesteremic Agents; Cataract; Cholesterol; Cholestyramine Resin; Creatine Kinase; Female; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lipoproteins; Lovastatin; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Simvastatin; Triglycerides	1990
Treatment of hypercholesterolemia with the HMG CoA reductase inhibitor, simvastatin. Cardiovascular drugs and therapy, 1989, Volume: 3, Issue:2 Topics: Adult; Anticholesteremic Agents; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lipoproteins; Lovastatin; Male; Middle Aged; Simvastatin	1989
Comparative effects of simvastatin and cholestyramine in treatment of patients with hypercholesterolaemia. European journal of clinical pharmacology, 1989, Volume: 36, Issue:5 Topics: Adult; Aged; Anticholesteremic Agents; Apolipoprotein A-I; Apolipoproteins A; Apolipoproteins B; Apoproteins; Cholestyramine Resin; Female; Humans; Hypercholesterolemia; Lipids; Lipoproteins; Lovastatin; Male; Middle Aged; Patient Compliance; Simvastatin; Time Factors	1989
Effects of simvastatin and fenofibrate on serum lipoproteins and apolipoproteins in primary hypercholesterolaemia. European journal of clinical pharmacology, 1989, Volume: 37, Issue:2 Topics: Adult; Aged; Anticholesteremic Agents; Apolipoprotein A-I; Apolipoprotein A-II; Apolipoproteins; Apolipoproteins A; Apolipoproteins B; Cholesterol, HDL; Female; Fenofibrate; Humans; Hypercholesterolemia; Lipoproteins; Lipoproteins, LDL; Lovastatin; Male; Middle Aged; Propionates; Simvastatin; Triglycerides	1989
Effects of simvastatin and probucol in hypercholesterolemia (Simvastatin Multicenter Study Group II). The American journal of cardiology, 1989, Mar-15, Volume: 63, Issue:11 Topics: Adult; Aged; Anticholesteremic Agents; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Multicenter Studies as Topic; Phenols; Probucol; Random Allocation; Simvastatin	1989
Lovastatin in the treatment of multifactorial hyperlipidemia associated with proteinuria. American journal of kidney diseases : the official journal of the National Kidney Foundation, 1989, Volume: 13, Issue:4 Topics: Adrenal Cortex Hormones; Adult; Cholesterol, Dietary; Cholesterol, HDL; Cholesterol, LDL; Clinical Trials as Topic; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Nephrotic Syndrome; Proteinuria; Random Allocation	1989
Simvastatin (MK 733): an effective treatment for hypercholesterolemia. Australian and New Zealand journal of medicine, 1989, Volume: 19, Issue:4 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Cholesterol, LDL; Cholestyramine Resin; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Random Allocation; Simvastatin	1989
Simvastatin and cholestyramine in the long-term treatment of hypercholesterolaemia. Journal of internal medicine, 1989, Volume: 226, Issue:5 Topics: Adult; Aged; Alanine Transaminase; Anticholesteremic Agents; Cholestyramine Resin; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Random Allocation; Simvastatin; Time Factors	1989
Comparison between low-dose simvastatin and cholestyramine in moderately severe hypercholesterolemia. Acta cardiologica, 1989, Volume: 44, Issue:5 Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Drug Administration Schedule; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Simvastatin	1989
[Effects of lovastatin in primary hypercholesterolemia]. Arquivos brasileiros de cardiologia, 1989, Volume: 52, Issue:5 Topics: Adolescent; Adult; Aged; Cholesterol; Cholesterol, LDL; Clinical Trials as Topic; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged	1989
[Swiss simvastatin multicenter study: 1. Efficacy of 10 mg simvastatin daily in patients with primary hypercholesterolemia]. Schweizerische medizinische Wochenschrift, 1989, Dec-02, Volume: 119, Issue:48 Topics: Adult; Aged; Anticholesteremic Agents; Apolipoproteins; Cholesterol; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lipoproteins; Lovastatin; Middle Aged; Multicenter Studies as Topic; Simvastatin; Single-Blind Method; Switzerland	1989
[Effects of simvastatin on plasma levels of lipids, lipoproteins and apolipoproteins in primary hypercholesterolemia]. Minerva cardioangiologica, 1989, Volume: 37, Issue:12 Topics: Anticholesteremic Agents; Apolipoproteins; Clinical Trials as Topic; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lipoproteins; Lovastatin; Male; Middle Aged; Simvastatin; Time Factors	1989
Comparison between simvastatin and bezafibrate in effect on plasma lipoproteins and apolipoproteins in primary hypercholesterolaemia. Lancet (London, England), 1988, Mar-19, Volume: 1, Issue:8586 Topics: Adult; Aged; Apolipoproteins; Apolipoproteins B; Bezafibrate; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lipoproteins; Lipoproteins, VLDL; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides	1988
A multicenter comparison of lovastatin and cholestyramine therapy for severe primary hypercholesterolemia. The Lovastatin Study Group III. JAMA, 1988, Jul-15, Volume: 260, Issue:3 Topics: Adult; Aged; Alkaline Phosphatase; Apolipoproteins; Cholesterol; Cholestyramine Resin; Creatine Kinase; Female; Humans; Hypercholesterolemia; Lipoproteins; Lovastatin; Male; Middle Aged; Random Allocation; Transaminases; Triglycerides	1988
[Effects on lipid metabolism of inhibitors of cholesterol synthesis]. La Clinica terapeutica, 1988, Apr-15, Volume: 125, Issue:1 Topics: Aged; Anticholesteremic Agents; Cholesterol; Clinical Trials as Topic; Clofibrate; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lipid Metabolism; Lipids; Lovastatin; Male; Middle Aged; Niacin; Triglycerides	1988
Efficacy and long-term adverse effect pattern of lovastatin. The American journal of cardiology, 1988, Nov-11, Volume: 62, Issue:15 Topics: Alanine Transaminase; Clinical Trials as Topic; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Liver; Lovastatin; Muscular Diseases; Time Factors	1988
Comparison between lovastatin and gemfibrozil in the treatment of primary hypercholesterolemia: the Finnish Multicenter Study. The American journal of cardiology, 1988, Nov-11, Volume: 62, Issue:15 Topics: Adult; Double-Blind Method; Female; Finland; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Multicenter Studies as Topic; Random Allocation	1988
Treatment of dyslipidemia in non-insulin-dependent diabetes mellitus with lovastatin. The American journal of cardiology, 1988, Nov-11, Volume: 62, Issue:15 Topics: Clinical Trials as Topic; Coronary Disease; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Random Allocation	1988
Comparison of lovastatin and probucol in treatment of familial and non-familial hypercholesterolemia: different effects on lipoprotein profiles. Atherosclerosis, 1988, Volume: 72, Issue:2-3 Topics: Apolipoproteins; Clinical Trials as Topic; Genetic Carrier Screening; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lipase; Lipoprotein Lipase; Lipoproteins; Lovastatin; Phenols; Probucol; Random Allocation	1988
New developments in lipid-lowering therapy: the role of inhibitors of hydroxymethylglutaryl-coenzyme A reductase. Circulation, 1987, Volume: 76, Issue:3 Topics: Animals; Anticholesteremic Agents; Apolipoproteins B; Cholesterol; Cholesterol, LDL; Cholesterol, VLDL; Clinical Trials as Topic; Dogs; Double-Blind Method; Drug Evaluation; Drug Tolerance; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lipoproteins, HDL; Lipoproteins, VLDL; Lovastatin; Middle Aged; Naphthalenes; Pravastatin; Simvastatin; Triglycerides	1987
Lovastatin for hypercholesterolemia. The Medical letter on drugs and therapeutics, 1987, Nov-06, Volume: 29, Issue:752 Topics: Cataract; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Humans; Hypercholesterolemia; Lovastatin; Myositis; Random Allocation	1987
Therapeutic response to lovastatin (mevinolin) in nonfamilial hypercholesterolemia. A multicenter study. The Lovastatin Study Group II. JAMA, 1986, Nov-28, Volume: 256, Issue:20 Topics: Anticholesteremic Agents; Apolipoproteins; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Naphthalenes	1986
Treatment of primary moderate hypercholesterolemia with lovastatin (mevinolin) and colestipol. JAMA, 1987, Jan-02, Volume: 257, Issue:1 Topics: Aged; Anticholesteremic Agents; Apolipoproteins; Cholesterol, HDL; Cholesterol, LDL; Clinical Trials as Topic; Colestipol; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Kinetics; Lipids; Lovastatin; Male; Middle Aged; Naphthalenes; Polyamines	1987
Influence of mevinolin on metabolism of low density lipoproteins in primary moderate hypercholesterolemia. Journal of lipid research, 1985, Volume: 26, Issue:12 Topics: Aged; Anticholesteremic Agents; Apolipoproteins B; Cholesterol; Humans; Hypercholesterolemia; Kinetics; Lipoproteins, LDL; Lovastatin; Male; Middle Aged; Naphthalenes; Triglycerides	1985

Other Studies

337 other study(ies) available for lovastatin and Elevated Cholesterol

Article	Year
Synthesis, DNA binding, and cytotoxic evaluation of new analogs of diallyldisulfide, an active principle of garlic. Bioorganic & medicinal chemistry, 2008, Aug-01, Volume: 16, Issue:15 Topics: Allyl Compounds; Animals; Antineoplastic Agents, Phytogenic; Cells, Cultured; Circular Dichroism; DNA; Garlic; Hepatocytes; Hypercholesterolemia; Hypolipidemic Agents; Male; Nucleic Acid Denaturation; Rats; Rats, Wistar; Sulfides	2008
Effects of monacolin K-containing nutraceutical on cholesterol homeostasis re-establishment and CVD risk reduction in hypercholesterolemic subjects. European review for medical and pharmacological sciences, 2021, Volume: 25, Issue:16 Topics: Aged; Anticholesteremic Agents; Cardiovascular Diseases; Cholesterol; Cholesterol, LDL; Chromatography, High Pressure Liquid; Dietary Supplements; Female; Heart Disease Risk Factors; Humans; Hypercholesterolemia; Longitudinal Studies; Lovastatin; Male; Middle Aged; Risk Reduction Behavior; Tandem Mass Spectrometry; Triglycerides	2021
Modulatory action of withaferin-A on oxidative damage through regulation of inflammatory mediators and apoptosis via PI3K/AKT signaling pathway in high cholesterol-induced atherosclerosis in experimental rats. Journal of biochemical and molecular toxicology, 2022, Volume: 36, Issue:10 Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Atherosclerosis; Caspase 3; Cholesterol; Cytokines; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Inflammation Mediators; Lovastatin; Male; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Receptors, Tumor Necrosis Factor; Signal Transduction	2022
[Nutraceuticals (monacolin K, berberine and coenzyme Q10) in patients with moderate hypercholesterolemia and low-moderate cardiovascular risk. Potential benefits of combined therapies]. Semergen, 2023, Volume: 49, Issue:2 Topics: Berberine; Cardiovascular Diseases; Dietary Supplements; Heart Disease Risk Factors; Humans; Hypercholesterolemia; Lovastatin; Risk Factors	2023
Hypocholesterolemic activity of cornelian cherry (Cornus mas L.) fruits. Journal of complementary & integrative medicine, 2017, Jun-01, Volume: 14, Issue:4 Topics: Animals; Anticholesteremic Agents; Antioxidants; Blood Glucose; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cornaceae; Diabetes Mellitus, Experimental; Fruit; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Liver; Lovastatin; Male; Phytotherapy; Plant Extracts; Powders; Rats, Wistar	2017
Alginate-gelatin formulation to modify lovastatin release profile from red yeast rice for hypercholesterolemia therapy. Therapeutic delivery, 2017, Volume: 8, Issue:10 Topics: Alginates; Biological Products; Delayed-Action Preparations; Drug Carriers; Drug Liberation; Gelatin; Glucuronic Acid; Hexuronic Acids; Hypercholesterolemia; Lovastatin	2017
[Red yeast rice, monacolin K, and pleiotropic effects.] Recenti progressi in medicina, 2018, Volume: 109, Issue:2 Topics: Anticholesteremic Agents; Biological Products; Biomarkers; Cholesterol; Dietary Supplements; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Pulse Wave Analysis	2018
MK-2206, an allosteric inhibitor of AKT, stimulates LDLR expression and LDL uptake: A potential hypocholesterolemic agent. Atherosclerosis, 2018, Volume: 276 Topics: Anticholesteremic Agents; Biological Transport; Cholesterol, LDL; HeLa Cells; Hep G2 Cells; Hepatocytes; Heterocyclic Compounds, 3-Ring; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Protein Kinase Inhibitors; Proteolysis; Proto-Oncogene Proteins c-akt; Receptors, LDL; Signal Transduction; Sterol Regulatory Element Binding Protein 2	2018
Statins Can Lead to Acute Hemolysis. Cardiovascular & hematological agents in medicinal chemistry, 2018, Volume: 16, Issue:2 Topics: Adult; Anemia, Hemolytic; Atorvastatin; Female; Hemolysis; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Rosuvastatin Calcium	2018
Screening of indigenously isolated fungi for lovastatin production and its in vivo evaluation. Current pharmaceutical biotechnology, 2014, Volume: 15, Issue:4 Topics: Alanine Transaminase; Animals; Anticholesteremic Agents; Aspartate Aminotransferases; Cholesterol; Fermentation; Fungi; Hydrogen-Ion Concentration; Hypercholesterolemia; Lovastatin; Male; Rats; Temperature; Triglycerides	2014
Lipophilic statin use and suicidal ideation in a sample of adults with mood disorders. Crisis, 2014, Jan-01, Volume: 35, Issue:4 Topics: Adult; Bipolar Disorder; Cross-Sectional Studies; Depressive Disorder; Depressive Disorder, Major; Dietary Fats; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Risk Factors; Simvastatin; Suicidal Ideation	2014
[Dyslipidemia. Red rice supplements change in nutrition]. MMW Fortschritte der Medizin, 2014, Dec-15, Volume: 156, Issue:21-22 Topics: Anticholesteremic Agents; Combined Modality Therapy; Dietary Supplements; Humans; Hypercholesterolemia; Life Style; Lovastatin; Oryza; Randomized Controlled Trials as Topic; Weight Loss	2014
Simvastatin increases AQP2 urinary excretion in hypercholesterolemic patients: A pleiotropic effect of interest for patients with impaired AQP2 trafficking. Clinical pharmacology and therapeutics, 2016, Volume: 99, Issue:5 Topics: Adult; Aged; Anticholesteremic Agents; Aquaporin 2; Diuresis; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Osmolar Concentration; Simvastatin; Time Factors	2016
Proprotein Convertase Subtilisin Kexin Type 9 Inhibition for Autosomal Recessive Hypercholesterolemia-Brief Report. Arteriosclerosis, thrombosis, and vascular biology, 2016, Volume: 36, Issue:8 Topics: Adaptor Proteins, Signal Transducing; Adolescent; Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Case-Control Studies; Cells, Cultured; Cholesterol, LDL; Drug Therapy, Combination; Female; Genetic Predisposition to Disease; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipoproteinemia Type III; Lovastatin; Lymphocytes; Male; Middle Aged; Mutation; PCSK9 Inhibitors; Phenotype; Proprotein Convertase 9; Receptors, LDL; Serine Proteinase Inhibitors; Young Adult	2016
Statins increase hepatic cholesterol synthesis and stimulate fecal cholesterol elimination in mice. Journal of lipid research, 2016, Volume: 57, Issue:8 Topics: Animals; Cholesterol; Drug Evaluation, Preclinical; Gene Expression; Glutarates; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intestinal Elimination; Intestine, Small; Liver; Lovastatin; Male; Mice, Inbred C57BL	2016
The blood lipid regulation of Monascus-produced monascin and ankaflavin via the suppression of low-density lipoprotein cholesterol assembly and stimulation of apolipoprotein A1 expression in the liver. Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2018, Volume: 51, Issue:1 Topics: Acetyl-CoA C-Acetyltransferase; Animals; Apolipoprotein A-I; Apolipoprotein B-100; Bile Acids and Salts; Body Weight; Carrier Proteins; Cholesterol, HDL; Cholesterol, LDL; Diet, High-Fat; Eating; Feces; Fermentation; Flavins; Heterocyclic Compounds, 3-Ring; Hypercholesterolemia; Lipids; Liver; Lovastatin; Male; Monascus; Rats	2018
Nonenzymatic Mechanism of Statins in Modulating Cholesterol Particles Formation. The American journal of cardiology, 2016, Oct-15, Volume: 118, Issue:8 Topics: Atorvastatin; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Flow Cytometry; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; In Vitro Techniques; Lovastatin; Pilot Projects; Prodrugs; Simvastatin	2016
A short-term statin treatment changes the contractile properties of fast-twitch skeletal muscles. BMC musculoskeletal disorders, 2016, 10-28, Volume: 17, Issue:1 Topics: Animals; Creatine Kinase; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Isometric Contraction; Lovastatin; Male; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch	2016
Effects of rutin on lipid profile in hypercholesterolaemic rats. Basic & clinical pharmacology & toxicology, 2009, Volume: 104, Issue:3 Topics: Animals; Anticholesteremic Agents; Cholesterol; Cholesterol, Dietary; Cholesterol, LDL; Dose-Response Relationship, Drug; Drug Therapy, Combination; Hypercholesterolemia; Liver; Lovastatin; Male; Organ Size; Rats; Rats, Wistar; Rutin	2009
The g.-762T>C polymorphism of the NPC1L1 gene is common in Chinese and contributes to a higher promoter activity and higher serum cholesterol levels. Journal of human genetics, 2009, Volume: 54, Issue:4 Topics: Asian People; Azetidines; China; Cholesterol; Demography; Ezetimibe; Female; Gene Frequency; Genotype; Hep G2 Cells; Humans; Hypercholesterolemia; Lovastatin; Male; Membrane Proteins; Membrane Transport Proteins; Middle Aged; Polymorphism, Single Nucleotide; Promoter Regions, Genetic	2009
Regulation of steroid 5-alpha reductase type 2 (Srd5a2) by sterol regulatory element binding proteins and statin. Experimental cell research, 2009, Nov-01, Volume: 315, Issue:18 Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Animals; Atorvastatin; Azetidines; Cell Line, Tumor; Ezetimibe; Gene Expression Regulation, Enzymologic; Heptanoic Acids; Hydroxymethylglutaryl CoA Reductases; Hypercholesterolemia; Liver; Lovastatin; Male; Mice; Promoter Regions, Genetic; Prostate; Prostatic Neoplasms; Pyrroles; Sterol Regulatory Element Binding Protein 2; Transfection	2009
Lovastatin decreases acute mucosal inflammation via 15-epi-lipoxin A4. Mucosal immunology, 2010, Volume: 3, Issue:3 Topics: 8,11,14-Eicosatrienoic Acid; Acute Disease; Animals; Anticholesteremic Agents; Cell Line; Disease Models, Animal; Female; Humans; Hypercholesterolemia; Inflammation; Inflammation Mediators; Lipoxins; Lovastatin; Male; Mice; Neutrophils; Pneumonia; Respiratory Mucosa	2010
[Pharmaco-economic optimization of cholesterol-lowering treatment with statins]. Medicina clinica, 2011, Jun-25, Volume: 137, Issue:3 Topics: Atorvastatin; Cholesterol, LDL; Cost-Benefit Analysis; Fatty Acids, Monounsaturated; Fluorobenzenes; Fluvastatin; Goals; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Practice Guidelines as Topic; Pravastatin; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Simvastatin; Spain; Sulfonamides	2011
Is red yeast rice safe and effective for lowering serum cholesterol? Journal of the American Dietetic Association, 2011, Volume: 111, Issue:2 Topics: Biological Products; Cholesterol; Dietary Supplements; Fermentation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Treatment Outcome	2011
Antioxidant effect of red mould rice in hypercholesterolemic Wistar male rats. Cell biochemistry and function, 2011, Volume: 29, Issue:7 Topics: Animals; Antioxidants; Ascorbic Acid; Catalase; Cholesterol; Fermentation; Glutathione Reductase; Hypercholesterolemia; Lipid Peroxidation; Liver; Lovastatin; Male; Monascus; Oryza; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase	2011
[Cholesterol-degrading in mice by Lactobacillus plantarum LpT1 and LpT2 in vivo]. Wei sheng wu xue bao = Acta microbiologica Sinica, 2012, Volume: 52, Issue:1 Topics: Animals; Cholesterol; Cholesterol, HDL; Disease Models, Animal; Hypercholesterolemia; Lactobacillus plantarum; Liver; Lovastatin; Male; Rats; Rats, Sprague-Dawley	2012
[Achievement of therapeutic target in subjects on statin treatment in clinical practice. Results of the STAR (Statins Target Assessment in Real practice) study]. Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 2011, Volume: 76, Issue:4 Topics: Aged; Algorithms; Azetidines; Biomarkers; Cardiovascular Diseases; Cerebrovascular Disorders; Cholesterol, LDL; Cohort Studies; Diabetes Complications; Diabetes Mellitus; Ezetimibe; Female; Fluorobenzenes; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Italy; Lovastatin; Male; Medication Adherence; Middle Aged; Pravastatin; Pyrimidines; Retrospective Studies; Risk Assessment; Risk Factors; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Treatment Outcome	2011
JD induced pluripotent stem cell-derived hepatocytes faithfully recapitulate the pathophysiology of familial hypercholesterolemia. Hepatology (Baltimore, Md.), 2012, Volume: 56, Issue:6 Topics: Adolescent; Alleles; Anticholesteremic Agents; Apolipoprotein B-100; Cell Differentiation; Cells, Cultured; Cholesterol, LDL; Fibroblasts; Gene Expression Regulation; Genome-Wide Association Study; Hepatocytes; Humans; Hypercholesterolemia; Lipoproteins, LDL; Lovastatin; Male; Mutation; Pluripotent Stem Cells; Receptors, LDL; RNA, Messenger; Sterol Regulatory Element Binding Protein 2	2012
Policosanol safely down-regulates HMG-CoA reductase - potential as a component of the Esselstyn regimen. Medical hypotheses, 2002, Volume: 59, Issue:3 Topics: Animals; Cholesterol, LDL; Clinical Trials as Topic; Cohort Studies; Diet, Vegetarian; Dietary Fats; Dietary Supplements; Double-Blind Method; Drug Costs; Enzyme Activation; Fatty Alcohols; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Insulin Resistance; Lovastatin; Myocardial Infarction; Platelet Activation; Protein Prenylation; Protein Processing, Post-Translational; Rabbits; Rats; rho GTP-Binding Proteins; Safety	2002
Frequency of new coronary events in older persons with peripheral arterial disease and serum low-density lipoprotein cholesterol > or = 125 mg/dl treated with statins versus no lipid-lowering drug. The American journal of cardiology, 2002, Oct-01, Volume: 90, Issue:7 Topics: Aged; Aged, 80 and over; Anticholesteremic Agents; Cholesterol, HDL; Cholesterol, LDL; Female; Follow-Up Studies; Health Services for the Aged; Humans; Hypercholesterolemia; Incidence; Lovastatin; Male; Middle Aged; Myocardial Infarction; New York; Peripheral Vascular Diseases; Pravastatin; Prospective Studies; Simvastatin; Treatment Outcome; Triglycerides	2002
Effect of fruits of Moringa oleifera on the lipid profile of normal and hypercholesterolaemic rabbits. Journal of ethnopharmacology, 2003, Volume: 86, Issue:2-3 Topics: Animals; Cholesterol, HDL; Fruit; Hypercholesterolemia; Hypolipidemic Agents; Lipids; Lovastatin; Male; Moringa oleifera; Phytotherapy; Plant Preparations; Rabbits	2003
Thyroid hormone regulation and cholesterol metabolism are connected through Sterol Regulatory Element-Binding Protein-2 (SREBP-2). The Journal of biological chemistry, 2003, Sep-05, Volume: 278, Issue:36 Topics: Animals; Anticholesteremic Agents; Blotting, Northern; Cell Line; Cell Nucleus; Cholesterol; DNA-Binding Proteins; Gene Expression Regulation; Humans; Hypercholesterolemia; Hypothyroidism; Lipoproteins, LDL; Liver; Lovastatin; Male; Mice; Plasmids; Promoter Regions, Genetic; Protein Binding; Ribonucleases; RNA, Messenger; Sterol Regulatory Element Binding Protein 2; Thyroid Hormones; Transcription Factors; Transfection	2003
Allocation of resources between smoking cessation methods and lovastatin treatment of hypercholesterolaemia: based on cost effectiveness and the social welfare function. PharmacoEconomics, 2004, Volume: 22, Issue:1 Topics: Administration, Cutaneous; Administration, Oral; Algorithms; Anticholesteremic Agents; Cost-Benefit Analysis; Female; Health Care Rationing; Humans; Hypercholesterolemia; Lovastatin; Male; Nicotine; Smoking Cessation; Social Welfare; Socioeconomic Factors; Spain	2004
Eggplant (Solanum melongena) extract does not alter serum lipid levels. Arquivos brasileiros de cardiologia, 2004, Volume: 82, Issue:3 Topics: Anticholesteremic Agents; Beverages; Case-Control Studies; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Citrus sinensis; Female; Fruit; Humans; Hypercholesterolemia; Lipids; Lovastatin; Male; Phytotherapy; Plant Extracts; Plant Preparations; Solanum melongena; Triglycerides	2004
Lichenoid drug eruption with HMG-CoA reductase inhibitors (fluvastatin and lovastatin). Acta dermato-venereologica, 2004, Volume: 84, Issue:3 Topics: Drug Eruptions; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lichen Planus; Lovastatin; Middle Aged	2004
[Idiopathic membranous nephropathy associated with anti-calcineurin toxicity. Prognosis and other immunosuppressive treatments]. Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2004, Volume: 24 Suppl 3 Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcineurin Inhibitors; Calcium Channel Blockers; Creatinine; Cyclosporine; Drug Therapy, Combination; Glomerulonephritis, Membranous; Humans; Hypercholesterolemia; Hypertension; Hypolipidemic Agents; Immunosuppressive Agents; Kidney Diseases; Lisinopril; Lovastatin; Male; Nephrotic Syndrome; Prednisone; Recurrence; Verapamil	2004
Therapeutic effects of ml-236B in primary hypercholesterolemia. 1980. Atherosclerosis. Supplements, 2004, Volume: 5, Issue:3 Topics: History, 20th Century; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin	2004
Consistency in efficacy and safety of ezetimibe coadministered with statins for treatment of hypercholesterolemia in women and men. Journal of women's health (2002), 2004, Volume: 13, Issue:10 Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Sex Factors; Simvastatin; Time Factors; Treatment Outcome; Women's Health	2004
Reviewing your investment strategy: where does diet fit in your personal portfolio. The American journal of clinical nutrition, 2005, Volume: 81, Issue:2 Topics: Anticholesteremic Agents; Cholesterol, Dietary; Cholesterol, LDL; Diet; Humans; Hypercholesterolemia; Lovastatin; Treatment Outcome	2005
[The "healthy" patient with hypercholesterolemia]. Medizinische Klinik (Munich, Germany : 1983), 2005, Feb-15, Volume: 100, Issue:2 Topics: Aged; Aged, 80 and over; Anticholesteremic Agents; Antihypertensive Agents; Cholesterol, LDL; Clinical Trials as Topic; Coronary Disease; Female; Follow-Up Studies; Geriatric Assessment; Health Status; Humans; Hypercholesterolemia; Hypertension; Lipoprotein(a); Lovastatin; Practice Guidelines as Topic; Risk Factors	2005
Risks of a nonprescription lovastatin. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2005, Jul-15, Volume: 62, Issue:14 Topics: Anticholesteremic Agents; Drug Approval; Humans; Hypercholesterolemia; Lovastatin; Nonprescription Drugs; Risk; United States; United States Food and Drug Administration	2005
[Hypothyroidism and lovastatin-induced myositis]. Anales de medicina interna (Madrid, Spain : 1984), 2005, Volume: 22, Issue:5 Topics: Aged; Diabetes Mellitus, Type 2; Disease Susceptibility; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypothyroidism; Lovastatin; Myositis	2005
Successful conversion of patients with hypercholesterolemia from a brand name to a generic cholesterol-lowering drug. The American journal of managed care, 2005, Volume: 11, Issue:9 Topics: Aged; Anticholesteremic Agents; California; Drug Prescriptions; Drugs, Generic; Female; Health Maintenance Organizations; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Practice Patterns, Physicians'; Simvastatin; Treatment Outcome	2005
Experience with statin use in patients with chronic hepatitis C infection. The American journal of cardiology, 2005, Nov-01, Volume: 96, Issue:9 Topics: Aged; Alanine Transaminase; Anticholesteremic Agents; Aspartate Aminotransferases; Biomarkers; Cholesterol; Hepatitis C, Chronic; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Prevalence; Simvastatin; Treatment Outcome; United States	2005
[Impact of dietotherapy with enterosorbent of marine origin on the indices of mineral and lipid metabolism for patients suffering from kidney diseases]. Voprosy pitaniia, 2005, Volume: 74, Issue:4 Topics: Alginates; Anticholesteremic Agents; Data Interpretation, Statistical; Electrolytes; Enterosorption; Humans; Hypercholesterolemia; Kidney Diseases; Laminaria; Lipid Metabolism; Lovastatin; Middle Aged; Minerals; Pyelonephritis; Time Factors; Urinary Calculi	2005
Cost-effectiveness analysis of cholesterol-lowering therapies in Spain. American journal of cardiovascular drugs : drugs, devices, and other interventions, 2006, Volume: 6, Issue:3 Topics: Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Cholestyramine Resin; Clinical Trials as Topic; Coronary Disease; Cost-Benefit Analysis; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Meta-Analysis as Topic; Pravastatin; Pyrroles; Risk Factors; Simvastatin; Spain	2006
Neuropeptides induced a pronounced and statin-sensitive dysregulation of mevalonate cycle in human monocytes of patients with hypercholesterolemia. Neuropeptides, 2006, Volume: 40, Issue:5 Topics: Aged; Cell Separation; Cholesterol; Female; Humans; Hydroxycholesterols; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; In Vitro Techniques; Ligands; Lovastatin; Male; Mevalonic Acid; Middle Aged; Monocytes; Neuropeptides; Signal Transduction; Stimulation, Chemical; Superoxides	2006
Regulation of human cytochrome P450 4F2 expression by sterol regulatory element-binding protein and lovastatin. The Journal of biological chemistry, 2007, Feb-23, Volume: 282, Issue:8 Topics: Anticholesteremic Agents; Cell Line, Tumor; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Gene Expression Regulation, Enzymologic; Hepatocytes; Humans; Hydroxycholesterols; Hypercholesterolemia; Intracellular Signaling Peptides and Proteins; Lovastatin; Membrane Proteins; Mutation; Response Elements; Sterol Regulatory Element Binding Protein 1; Sterol Regulatory Element Binding Protein 2; Transcriptional Activation	2007
Hepatitis and rhabdomyolysis in a patient with hormone refractory prostate cancer on ketoconazole and concurrent lovastatin therapy. Investigational new drugs, 2007, Volume: 25, Issue:3 Topics: Aged, 80 and over; Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Drug Interactions; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Ketoconazole; Lovastatin; Male; Prostatic Neoplasms; Rhabdomyolysis; Treatment Outcome	2007
The effect of HMG-CoA reductase inhibitors on naturally occurring CD4+CD25+ T cells. Atherosclerosis, 2008, Volume: 197, Issue:2 Topics: Adult; Animals; Atorvastatin; Forkhead Transcription Factors; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Mice; Mice, Inbred C57BL; Pravastatin; Pyrroles; T-Lymphocytes, Regulatory; Up-Regulation	2008
Low-density lipoprotein cholesterol (LDL-C) levels and LDL-C goal attainment among elderly patients treated with rosuvastatin compared with other statins in routine clinical practice. The American journal of geriatric pharmacotherapy, 2007, Volume: 5, Issue:3 Topics: Aged; Aged, 80 and over; Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Cohort Studies; Coronary Disease; Databases, Factual; Fatty Acids, Monounsaturated; Female; Fluorobenzenes; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Male; Managed Care Programs; Odds Ratio; Pravastatin; Pyrimidines; Pyrroles; Retrospective Studies; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Treatment Outcome	2007
FDA advisers again reject nonprescription lovastatin. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2008, Jan-15, Volume: 65, Issue:2 Topics: Drug Approval; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Nonprescription Drugs; United States; United States Food and Drug Administration	2008
Ask the doctor. I saw a newspaper column that said red yeast rice is a safer, more effective way to treat high cholesterol than statin drugs. Is that true? Harvard heart letter : from Harvard Medical School, 2007, Volume: 18, Issue:1 Topics: Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Monascus; Oryza; Phytotherapy	2007
Statins impair antitumor effects of rituximab by inducing conformational changes of CD20. PLoS medicine, 2008, Mar-25, Volume: 5, Issue:3 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antibody-Dependent Cell Cytotoxicity; Antigens, CD20; Antineoplastic Agents; B-Lymphocytes; Cell Line, Tumor; Cholesterol; Cytotoxicity, Immunologic; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Lymphoma, B-Cell; Membrane Microdomains; Protein Conformation; Rituximab	2008
Effect of APOE genotype on lipid levels in patients with coronary heart disease during a 3-week inpatient rehabilitation program. Clinical pharmacology and therapeutics, 2008, Volume: 84, Issue:2 Topics: Adult; Aged; Alleles; Apolipoprotein E2; Apolipoprotein E3; Apolipoprotein E4; Apolipoproteins E; Atorvastatin; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Decision Making; Fatty Acids, Monounsaturated; Female; Fluvastatin; Genotype; Germany; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Inpatients; Linear Models; Lovastatin; Male; Middle Aged; Multivariate Analysis; Pravastatin; Predictive Value of Tests; Pyridines; Pyrroles; Simvastatin; Triglycerides	2008
Red yeast rice and omega-3 fatty acids for cholesterol management. South Dakota medicine : the journal of the South Dakota State Medical Association, 2008, Volume: 61, Issue:2 Topics: Biological Products; Cholesterol; Fatty Acids, Omega-3; Humans; Hypercholesterolemia; Lovastatin	2008
Can consumers self-select for appropriate use of an over-the-counter statin? The Self Evaluation of Lovastatin to Enhance Cholesterol Treatment Study. The American journal of cardiology, 2008, May-15, Volume: 101, Issue:10 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Cholesterol, LDL; Community Participation; Drug Labeling; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Nonprescription Drugs; Prevalence; Prospective Studies; Public Health; Risk Factors; Self-Evaluation Programs; Surveys and Questionnaires; United States	2008
Statin cost-effectiveness comparisons using real-world effectiveness data: formulary implications. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 2008, Volume: 11, Issue:7 Topics: Aged; Atorvastatin; Cholesterol, LDL; Cost-Benefit Analysis; Drugs, Generic; Female; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Pyrimidines; Pyrroles; Retrospective Studies; Rosuvastatin Calcium; Simvastatin; Sulfonamides	2008
Regulation of hepatic receptor-dependent degradation of LDL by mevinolin in rabbits with hypercholesterolemia induced by a wheat starch-casein diet. Biochimica et biophysica acta, 1983, Nov-29, Volume: 754, Issue:2 Topics: Animals; Anticholesteremic Agents; Caseins; Diet; Hypercholesterolemia; Lipoproteins, LDL; Lipoproteins, VLDL; Liver; Lovastatin; Male; Naphthalenes; Rabbits; Receptors, Cell Surface; Receptors, LDL; Starch	1983
Blocking 3-hydroxy-3-methylglutaryl coenzyme A reductase with ML-236B enhances the plasma cortisol response to adrenocorticotropin in patients with hypercholesterolemia. The Journal of clinical endocrinology and metabolism, 1984, Volume: 58, Issue:5 Topics: Adrenocorticotropic Hormone; Anticholesteremic Agents; Female; Humans; Hydrocortisone; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Naphthalenes	1984
The effects of mevinolin on serum cholesterol levels of rabbits with endogenous hypercholesterolemia. Atherosclerosis, 1982, Volume: 44, Issue:1 Topics: Animals; Anticholesteremic Agents; Caseins; Cholesterol; Diet; Dose-Response Relationship, Drug; Hypercholesterolemia; Lovastatin; Male; Naphthalenes; Rabbits; Time Factors; Triticum	1982
Effects of compactin (ML-236 B) on biliary lipid composition and cholesterol catabolism in the hamster. Pharmacological research communications, 1982, Volume: 14, Issue:7 Topics: Animals; Anticholesteremic Agents; Bile; Body Weight; Cholesterol; Cricetinae; Diet; Hypercholesterolemia; Lipid Metabolism; Liver; Lovastatin; Mesocricetus; Naphthalenes; Organ Size	1982
The effect of compactin, a potent inhibitor of 3-hydroxy-3-methylglutaryl coenzyme-A reductase activity, on cholesterogenesis and serum cholesterol levels in rats and chicks. Atherosclerosis, 1980, Volume: 35, Issue:4 Topics: Animals; Anticholesteremic Agents; Chickens; Cholesterol; Cholestyramine Resin; Circadian Rhythm; Dose-Response Relationship, Drug; Drug Therapy, Combination; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoproteins, HDL; Lipoproteins, VLDL; Lovastatin; Male; Naphthalenes; Rats	1980
Therapeutic effects of ML-236B in primary hypercholesterolemia. Atherosclerosis, 1980, Volume: 35, Issue:3 Topics: Adult; Aged; Anticholesteremic Agents; Child, Preschool; Cholesterol; Dose-Response Relationship, Drug; Drug Evaluation; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Naphthalenes	1980
Statins prevent coronary heart disease. Lancet (London, England), 1995, Nov-25, Volume: 346, Issue:8987 Topics: Anticholesteremic Agents; Cholesterol, LDL; Coronary Disease; Humans; Hydroxymethylglutaryl CoA Reductases; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Pravastatin; Randomized Controlled Trials as Topic; Risk Factors; Simvastatin	1995
Lovastatin and peripheral neuropathy. American heart journal, 1995, Volume: 130, Issue:6 Topics: Anticholesteremic Agents; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Peripheral Nervous System Diseases	1995
High retinol/retinol-binding protein ratio in noninsulin-dependent diabetes mellitus. The American journal of the medical sciences, 1995, Volume: 310, Issue:5 Topics: Anticholesteremic Agents; Antioxidants; Apolipoprotein C-II; Apolipoprotein C-III; Apolipoproteins C; beta Carotene; Blood Glucose; Carotenoids; Cholesterol; Diabetes Mellitus, Type 2; Diterpenes; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Retinol-Binding Proteins; Retinyl Esters; Sex Characteristics; Simvastatin; Triglycerides; Vitamin A	1995
Long-term treatment (2 years) with the HMG CoA reductase inhibitors lovastatin or pravastatin in combination with cholestyramine in patients with severe primary hypercholesterolemia. Journal of cardiovascular pharmacology, 1993, Volume: 22, Issue:3 Topics: Adult; Aged; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Pravastatin; Triglycerides	1993
Pharmaco-economic assessment of the HMG-CoA reductase inhibitors. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1994, Volume: 84, Issue:12 Topics: Anticholesteremic Agents; Cost Control; Cost-Benefit Analysis; Health Care Costs; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Pravastatin; Simvastatin	1994
[Is treatment of hypercholesterolemia able to reduce total mortality?]. Arquivos brasileiros de cardiologia, 1995, Volume: 64, Issue:2 Topics: Adult; Aged; Anticholesteremic Agents; Coronary Disease; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Risk Factors; Simvastatin	1995
Doctors, research funds and marketing. The Medical journal of Australia, 1995, Jun-19, Volume: 162, Issue:12 Topics: Advertising; Anticholesteremic Agents; Coronary Disease; Humans; Hypercholesterolemia; Lovastatin; Simvastatin	1995
Outcome monitoring of fluvastatin in a Department of Veterans Affairs lipid clinic. The American journal of cardiology, 1995, Jul-13, Volume: 76, Issue:2 Topics: Adult; Anticholesteremic Agents; Cholesterol, LDL; Coronary Disease; Cost Savings; Drug Costs; Drug Monitoring; Fatty Acids, Monounsaturated; Fluvastatin; Hospitals, Veterans; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; New York; Primary Prevention; Treatment Outcome; United States; United States Department of Veterans Affairs	1995
Marked improvement in cholestasis and hypercholesterolemia with simvastatin in a patient with primary biliary cirrhosis. The American journal of gastroenterology, 1995, Volume: 90, Issue:7 Topics: Adult; Anticholesteremic Agents; Cholestasis; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Liver Cirrhosis, Biliary; Lovastatin; Simvastatin	1995
[Rhabdomyolysis in patients treated with simvastatin and cyclosporin: role of the hepatic cytochrome P450 enzyme system activity]. Schweizerische medizinische Wochenschrift, 1995, Jul-11, Volume: 125, Issue:27-28 Topics: Anticholesteremic Agents; Cyclosporine; Cytochrome P-450 Enzyme Inhibitors; Heart Transplantation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Liver; Lovastatin; Male; Middle Aged; Rhabdomyolysis; Simvastatin	1995
Pravastatin versus simvastatin--what happens in the real world? South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1995, Volume: 85, Issue:5 Topics: Anticholesteremic Agents; Humans; Hypercholesterolemia; Lovastatin; Pravastatin; Product Surveillance, Postmarketing; Simvastatin	1995
Long-term effects of simvastatin in hypercholesterolemic patients with NIDDM and additional atherosclerotic risk factors. Hyogo Simvastatin Study Group. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1995, Volume: 27, Issue:5 Topics: Anticholesteremic Agents; Arteriosclerosis; Diabetes Mellitus, Type 2; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Prospective Studies; Risk Factors; Simvastatin	1995
Lovastatin-induced myopathy in a hypothyroid patient. The Journal of family practice, 1995, Volume: 41, Issue:3 Topics: Female; Humans; Hypercholesterolemia; Hypothyroidism; Lovastatin; Middle Aged; Muscular Diseases	1995
Effect of systemic treatment with cholesterol-lowering drugs on the skin barrier function in humans. Acta dermato-venereologica, 1995, Volume: 75, Issue:3 Topics: Adult; Aged; Anticholesteremic Agents; Biological Availability; Cholesterol; Erythema; Female; Galvanic Skin Response; Humans; Hypercholesterolemia; Irritants; Lovastatin; Male; Middle Aged; Patch Tests; Permeability; Pravastatin; Simvastatin; Skin; Sodium Dodecyl Sulfate; Water Loss, Insensible	1995
Lovastatin-induced hemolytic anemia: not a class-specific reaction. The American journal of medicine, 1995, Volume: 99, Issue:3 Topics: Anemia, Hemolytic; Female; Humans; Hypercholesterolemia; Lovastatin; Middle Aged	1995
Comparative effects of HMG-CoA reductase inhibitors on apo B production in the casein-fed rabbit: atorvastatin versus lovastatin. Atherosclerosis, 1995, Volume: 115, Issue:2 Topics: Analysis of Variance; Animals; Anticholesteremic Agents; Apolipoproteins B; Atorvastatin; Caseins; Cholesterol; Diet; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Iodine Radioisotopes; Lipoproteins, LDL; Lovastatin; Male; Pyrroles; Rabbits; Random Allocation	1995
Long-term safety of statin-fibrate combination treatment in the management of hypercholesterolaemia in patients with coronary artery disease. British heart journal, 1995, Volume: 74, Issue:1 Topics: Adult; Aged; Aspartate Aminotransferases; Bezafibrate; Cohort Studies; Coronary Disease; Creatine Kinase; Drug Therapy, Combination; Female; Fenofibrate; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Lovastatin; Male; Middle Aged; Pravastatin; Retrospective Studies; Simvastatin	1995
Decreased basal nitric oxide release in hypercholesterolemia increases neutrophil adherence to rabbit coronary artery endothelium. Arteriosclerosis and thrombosis : a journal of vascular biology, 1993, Volume: 13, Issue:6 Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Adhesion; Cholesterol, Dietary; Coronary Vessels; Endothelium, Vascular; Hypercholesterolemia; Lovastatin; Male; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rabbits	1993
Effects of simvastatin and pravastatin on endothelium-dependent relaxation in hypercholesterolemic rabbits. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1994, Volume: 46, Issue:6 Topics: Acetylcholine; Animals; Anticholesteremic Agents; Aorta, Thoracic; Cholesterol; Endothelium, Vascular; Hypercholesterolemia; In Vitro Techniques; Lovastatin; Male; Pravastatin; Rabbits; Simvastatin; Vasodilation	1994
Ocular drug safety and HMG-CoA-reductase inhibitors. Ophthalmic research, 1994, Volume: 26, Issue:6 Topics: Color Perception; Contrast Sensitivity; Eye; Female; Fenofibrate; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intraocular Pressure; Lens, Crystalline; Lovastatin; Male; Middle Aged; Photography; Refraction, Ocular; Safety; Simvastatin; Visual Acuity	1994
Renal transplantation and dyslipidemia: characterization of a population and treatment with diet and low dose lovastatin. Transplantation proceedings, 1995, Volume: 27, Issue:2 Topics: Adult; Cholesterol; Diet, Fat-Restricted; Female; Humans; Hypercholesterolemia; Kidney Transplantation; Lipoproteins, HDL; Lipoproteins, LDL; Lovastatin; Male; Postoperative Complications; Triglycerides	1995
The successful recruitment of elderly black subjects in a clinical trial: the CRISP experience. Cholesterol Reduction in Seniors Program. Journal of the National Medical Association, 1995, Volume: 87, Issue:4 Topics: Aged; Black People; Clinical Trials as Topic; Cohort Studies; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Lovastatin; Male; Patient Selection; Randomized Controlled Trials as Topic	1995
[Lovastatin-induced acute cholestatic hepatitis]. Deutsche medizinische Wochenschrift (1946), 1995, Feb-24, Volume: 120, Issue:8 Topics: Alkaline Phosphatase; Cholestasis, Intrahepatic; Cholinesterases; Female; Glutamate Dehydrogenase; Humans; Hypercholesterolemia; Liver; Lovastatin; Male; Middle Aged; Transaminases	1995
Cholesterol hypothesis vindicated by simvastatin study. Why did it take so long? The Canadian journal of cardiology, 1995, Volume: 11, Issue:3 Topics: Animals; Anticholesteremic Agents; Coronary Disease; Humans; Hypercholesterolemia; Lovastatin; Simvastatin	1995
The cost-effectiveness of HMG-CoA reductase inhibitors to prevent coronary heart disease. Estimating the benefits of increasing HDL-C. JAMA, 1995, Apr-05, Volume: 273, Issue:13 Topics: Adult; Age Factors; Aged; Canada; Cholesterol, HDL; Coronary Disease; Cost-Benefit Analysis; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Life Expectancy; Lovastatin; Male; Middle Aged; Models, Theoretical; Sex Factors; United States; Value of Life	1995
[Treatment of dyslipidemia of the elderly with simvastatin and pravastatin. Effectiveness and tolerance]. La Clinica terapeutica, 1994, Volume: 144, Issue:5 Topics: Aged; Cholesterol; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lovastatin; Middle Aged; Pravastatin; Simvastatin; Triglycerides	1994
Dropping cholesterol--safely. Science (New York, N.Y.), 1994, Nov-25, Volume: 266, Issue:5189 Topics: Cholesterol; Controlled Clinical Trials as Topic; Coronary Artery Bypass; Coronary Disease; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Scandinavian and Nordic Countries; Simvastatin	1994
[Effect of combined treatment with lovastatin and colestipol on serum lipids and lipoproteins]. Wiadomosci lekarskie (Warsaw, Poland : 1960), 1993, Volume: 46, Issue:15-16 Topics: Adult; Aged; Colestipol; Drug Therapy, Combination; Humans; Hypercholesterolemia; Hyperlipidemias; Lipids; Lipoproteins; Lovastatin; Male; Middle Aged	1993
Drug treatment of hypercholesterolaemia in a patient with Gilbert's syndrome. Annals of clinical biochemistry, 1994, Volume: 31 ( Pt 4) Topics: Administration, Oral; Bezafibrate; Bilirubin; Colestipol; Gilbert Disease; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lipids; Liver; Liver Function Tests; Lovastatin; Male; Middle Aged; Pravastatin; Pyrazines; Simvastatin	1994
Effects of lovastatin (20-80 mg daily) on lipoprotein fractions in patients with severe primary hypercholesterolemia. International journal of clinical pharmacology and therapeutics, 1994, Volume: 32, Issue:2 Topics: Adult; Aged; Apolipoproteins; Cholesterol; Dose-Response Relationship, Drug; Female; Humans; Hypercholesterolemia; Lipoproteins; Lovastatin; Male; Middle Aged; Triglycerides	1994
[The effects of plasma cholesterol reduction on vasoconstriction due to sympathetic activation in patients with moderate primary hypercholesterolemia]. Minerva medica, 1994, Volume: 85, Issue:4 Topics: Adult; Aged; Analysis of Variance; Anticholesteremic Agents; Cholesterol; Cold Temperature; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Linear Models; Lovastatin; Male; Middle Aged; Plethysmography; Simvastatin; Sympathetic Nervous System; Vasoconstriction	1994
Nicotinic acid as a lipoprotein-altering agent. Therapy directed by the primary physician. Archives of internal medicine, 1994, Jul-25, Volume: 154, Issue:14 Topics: Coronary Disease; Humans; Hypercholesterolemia; Lipoproteins; Lovastatin; Niacin	1994
Safety and efficacy of low dose simvastatin in cardiac transplant recipients treated with cyclosporine. Transplantation, 1994, Jul-15, Volume: 58, Issue:1 Topics: Anticholesteremic Agents; Cholesterol; Cyclosporine; Female; Follow-Up Studies; Graft Survival; Heart Transplantation; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides	1994
Prediction of the therapeutic response to simvastatin by pretreatment lipid concentrations in 2082 subjects. European journal of clinical pharmacology, 1994, Volume: 46, Issue:2 Topics: Adult; Aged; Anticholesteremic Agents; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lipoproteins; Lovastatin; Male; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Simvastatin; Treatment Outcome	1994
Hypercholesterolemia treatment in a renal transplant patient. Clinical nephrology, 1994, Volume: 41, Issue:5 Topics: Anticholesteremic Agents; Bezafibrate; Clofibric Acid; Female; Fenofibrate; Fibric Acids; Humans; Hypercholesterolemia; Kidney Transplantation; Lovastatin; Male; Middle Aged; Postoperative Complications; Simvastatin	1994
Acute hepatitis induced by HMG-CoA reductase inhibitor, lovastatin. Digestive diseases and sciences, 1994, Volume: 39, Issue:9 Topics: Acute Disease; Biopsy; Chemical and Drug Induced Liver Injury; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged	1994
Depressive symptoms and cholesterol-lowering drugs. Lancet (London, England), 1993, Jan-09, Volume: 341, Issue:8837 Topics: Adult; Anticholesteremic Agents; Depressive Disorder; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Middle Aged; Simvastatin	1993
Lovastatin versus pravastatin for hypercholesterolemia. The American journal of cardiology, 1994, Feb-15, Volume: 73, Issue:5 Topics: Cholesterol, LDL; Humans; Hypercholesterolemia; Lovastatin; Pravastatin	1994
"A real world" dose comparison of lovastatin and pravastatin. The American journal of cardiology, 1994, Feb-15, Volume: 73, Issue:5 Topics: Cholesterol; Cholesterol, LDL; Humans; Hypercholesterolemia; Lovastatin; Pravastatin	1994
Myxoedema revealed by simvastatin induced myopathy. BMJ (Clinical research ed.), 1994, Feb-26, Volume: 308, Issue:6928 Topics: Adult; Anticholesteremic Agents; Humans; Hypercholesterolemia; Lovastatin; Male; Muscular Diseases; Myxedema; Simvastatin	1994
[Effects of simvastatin on plasma lipoproteins]. La Clinica terapeutica, 1994, Volume: 144, Issue:1 Topics: Adult; Aged; Cholesterol; Female; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lipoproteins; Lovastatin; Male; Middle Aged; Retrospective Studies; Simvastatin	1994
HMG-CoA reductase inhibitor therapy and peripheral neuropathy. Annals of internal medicine, 1994, Jun-01, Volume: 120, Issue:11 Topics: Female; Humans; Hypercholesterolemia; Lovastatin; Middle Aged; Peripheral Nervous System Diseases; Pravastatin	1994
Lovastatin in pravastatin comparative trial: cost-effectiveness. The American journal of cardiology, 1994, Feb-15, Volume: 73, Issue:5 Topics: Cholesterol, LDL; Cost-Benefit Analysis; Humans; Hypercholesterolemia; Lovastatin; Pravastatin	1994
[Changes in the rate of cholesterol synthesis in lymphocytes, and blood lipid and lipoprotein levels in patients with ischemic heart disease and hypercholesterolemia during treatment with lovastatin and obsidan]. Biulleten' eksperimental'noi biologii i meditsiny, 1994, Volume: 117, Issue:3 Topics: Adult; Cholesterol; Drug Interactions; Drug Therapy, Combination; Humans; Hypercholesterolemia; Lipids; Lipoproteins; Lovastatin; Lymphocytes; Male; Middle Aged; Myocardial Ischemia; Propranolol	1994
[Use and effect of simvastin in patients with type II diabetes]. La Clinica terapeutica, 1993, Volume: 143, Issue:2 Topics: Anticholesteremic Agents; Cholesterol; Diabetes Mellitus, Type 2; Female; Humans; Hypercholesterolemia; Lipoproteins, HDL; Lipoproteins, LDL; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides	1993
Responsiveness to bradykinin in veins of hypercholesterolemic humans. Circulation, 1993, Volume: 88, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Bradykinin; Dose-Response Relationship, Drug; Drug Resistance; Endothelium, Vascular; Female; Humans; Hypercholesterolemia; Indomethacin; Lovastatin; Male; Middle Aged; Models, Cardiovascular; Nitric Oxide; Nitroglycerin; Vasodilation	1993
Plasma coenzyme Q (ubiquinone) concentrations in patients treated with simvastatin. Journal of clinical pathology, 1993, Volume: 46, Issue:11 Topics: Adult; Aged; Cholesterol; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Lipids; Lipoproteins; Lovastatin; Male; Middle Aged; Simvastatin; Ubiquinone	1993
Lovastatin enhances hepatic uptake of low density lipoprotein in humans. Journal of lipid research, 1993, Volume: 34, Issue:11 Topics: Adult; Apolipoproteins B; Cholesterol, LDL; Female; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Iodine Radioisotopes; Lipoproteins, LDL; Liver; Lovastatin; Lung; Male; Middle Aged; Myocardium; Technetium	1993
Effect of simvastatin treatment on plasma apolipoproteins and hepatic apolipoprotein mRNA levels in the genetically hypercholesterolemic rat (RICO). Life sciences, 1994, Volume: 54, Issue:5 Topics: Animals; Apolipoproteins E; Apoproteins; Gene Expression; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Lipoproteins; Liver; Lovastatin; Male; Phospholipids; Rats; Rats, Inbred Strains; RNA, Messenger; Simvastatin; Time Factors; Triglycerides	1994
Lovastatin decreases plasma and platelet cholesterol levels and normalizes elevated platelet fluidity and aggregation in hypercholesterolemic patients. Metabolism: clinical and experimental, 1994, Volume: 43, Issue:1 Topics: Administration, Oral; Adult; Blood Platelets; Cholesterol; Female; Fluorescence Polarization; Humans; Hypercholesterolemia; Lovastatin; Male; Membrane Fluidity; Middle Aged; Phosphatidylcholines; Phospholipids; Platelet Aggregation; Sphingomyelins	1994
Evidence of combined therapy of dyslipoproteinemia by HMG-CoA reductase inhibitors and "essential" phospholipids. La Clinica terapeutica, 1993, Volume: 142, Issue:4 Topics: Adult; Cholesterol; Coronary Disease; Drug Therapy, Combination; Humans; Hypercholesterolemia; Lipoproteins, LDL; Lovastatin; Male; Phosphatidylcholines; Platelet Aggregation	1993
Combination drug therapy for hypercholesterolemia. The trade-off between cost and simplicity. Archives of internal medicine, 1993, Aug-09, Volume: 153, Issue:15 Topics: Aged; Algorithms; Anticholesteremic Agents; Decision Trees; Drug Costs; Drug Therapy, Combination; Female; Hospitals, Veterans; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Midwestern United States; Niacin; Probability; Prospective Studies; Treatment Outcome	1993
A prospective study on treatment of hypercholesterolemia with lovastatin in renal transplant patients receiving cyclosporine. Journal of the American Society of Nephrology : JASN, 1993, Volume: 3, Issue:12 Topics: Adult; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cyclosporine; Female; Humans; Hypercholesterolemia; Kidney Transplantation; Lovastatin; Male; Middle Aged; Postoperative Care; Prospective Studies	1993
Musculoskeletal manifestations during simvastatin therapy. British journal of rheumatology, 1993, Volume: 32, Issue:7 Topics: Anticholesteremic Agents; Cholesterol; Female; Humans; Hypercholesterolemia; Lovastatin; Middle Aged; Musculoskeletal Diseases; Simvastatin	1993
Simvastatin, pravastatin and lovastatin: three options for lowering cholesterol. The Nurse practitioner, 1993, Volume: 18, Issue:5 Topics: Anticholesteremic Agents; Drug Costs; Drug Interactions; Humans; Hypercholesterolemia; Lovastatin; Pravastatin; Simvastatin	1993
Treatment of and screening for hyperlipidemia. The New England journal of medicine, 1993, Oct-07, Volume: 329, Issue:15 Topics: Cholesterol, LDL; Dietary Fats, Unsaturated; Humans; Hypercholesterolemia; Lovastatin	1993
Lovastatin vs PIB. The Journal of family practice, 1993, Volume: 36, Issue:1 Topics: Health Care Costs; Humans; Hypercholesterolemia; Jejunoileal Bypass; Lovastatin	1993
Effects of lovastatin on high-density lipoprotein subfractions in hypercholesterolemic patients with peripheral vascular disease. Angiology, 1993, Volume: 44, Issue:2 Topics: Adult; Apolipoprotein A-I; Apolipoprotein A-II; Arteriosclerosis; Case-Control Studies; Cholesterol, HDL; Female; Humans; Hypercholesterolemia; Intermittent Claudication; Lipids; Lipoproteins, HDL; Lipoproteins, HDL2; Lipoproteins, HDL3; Lovastatin; Male; Middle Aged; Peripheral Vascular Diseases	1993
Evaluation of the effectiveness of lipid-lowering therapy (bile acid sequestrants, niacin, psyllium and lovastatin) for treating hypercholesterolemia in veterans. The American journal of cardiology, 1993, Apr-01, Volume: 71, Issue:10 Topics: Age Factors; Anticholesteremic Agents; Cholesterol; Humans; Hypercholesterolemia; Lovastatin; Middle Aged; Niacin; Patient Compliance; Prospective Studies; Psyllium; Regression Analysis; Treatment Refusal; United States; Veterans	1993
Hypercholesterolemia in non-insulin-dependent diabetes mellitus: different effect of simvastatin on VLDL and LDL cholesterol levels. Atherosclerosis, 1993, Volume: 99, Issue:1 Topics: Anticholesteremic Agents; Apolipoproteins; Cholesterol, LDL; Cholesterol, VLDL; Diabetes Mellitus, Type 2; Female; Humans; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Simvastatin	1993
[Effectiveness and tolerability of simvastatin in patients with moderate-to-severe hypercholesterolemia. Results of a 12-month study]. Minerva cardioangiologica, 1993, Volume: 41, Issue:3 Topics: Anticholesteremic Agents; Cholesterol; Coronary Disease; Enzyme Inhibitors; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoproteins, LDL; Lovastatin; Male; Risk Factors; Severity of Illness Index; Simvastatin	1993
HMGCoA reductase inhibitors. The Canadian journal of cardiology, 1993, Volume: 9, Issue:4 Topics: Anticholesteremic Agents; Coronary Disease; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male	1993
Effect of lovastatin on cholesterol absorption in cholesterol-fed rabbits. Pharmacology & toxicology, 1993, Volume: 72, Issue:3 Topics: Animals; Cholesterol; Cholesterol, Dietary; Hypercholesterolemia; Intestinal Absorption; Lovastatin; Male; Rabbits; Sitosterols	1993
Profiling a landmark clinical trial: Scandinavian Simvastatin Survival Study. Current opinion in lipidology, 1995, Volume: 6, Issue:5 Topics: Adult; Aged; Anticholesteremic Agents; Clinical Trials as Topic; Coronary Disease; Diet Therapy; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Risk; Scandinavian and Nordic Countries; Simvastatin; Survival Analysis	1995
Thromboxane biosynthesis, neutrophil and coagulative activation in type IIa hypercholesterolemia. Thrombosis and haemostasis, 1995, Volume: 74, Issue:4 Topics: Adult; Aged; Cross-Sectional Studies; Female; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lovastatin; Male; Middle Aged; Neutrophil Activation; Pancreatic Elastase; Simvastatin; Thrombin; Thromboxanes	1995
[The 4-S study--a turning point in the cholesterol debate. Work Group Lipids and Atherosclerosis of the Swiss Society for Cardiology]. Praxis, 1995, Dec-19, Volume: 84, Issue:51-52 Topics: Adult; Aged; Anticholesteremic Agents; Coronary Disease; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Randomized Controlled Trials as Topic; Scandinavian and Nordic Countries; Simvastatin	1995
Vestibular vertigo and lovastatin therapy. Southern medical journal, 1996, Volume: 89, Issue:2 Topics: Aged; Anticholesteremic Agents; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Vertigo	1996
Treating hypercholesterolemia aggressively. The Nebraska medical journal, 1996, Volume: 81, Issue:1 Topics: Anticholesteremic Agents; Cholesterol, LDL; Clinical Trials as Topic; Combined Modality Therapy; Coronary Disease; Diet, Fat-Restricted; Humans; Hypercholesterolemia; Lovastatin; Practice Guidelines as Topic; Simvastatin	1996
Statins, cholesterol, and mevalonate pathways? Lancet (London, England), 1996, Feb-24, Volume: 347, Issue:9000 Topics: Anticholesteremic Agents; Cholesterol; Coronary Disease; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Mevalonic Acid; Simvastatin	1996
Implementation of the 4S study in first myocardial infarction. Lancet (London, England), 1996, Feb-24, Volume: 347, Issue:9000 Topics: Anticholesteremic Agents; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Myocardial Infarction; Simvastatin	1996
Simvastatin-oral anticoagulant interaction. Lancet (London, England), 1996, Feb-10, Volume: 347, Issue:8998 Topics: Acenocoumarol; Aged; Anticholesteremic Agents; Anticoagulants; Drug Synergism; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Simvastatin; Thrombosis	1996
Primary prevention of stroke. The New England journal of medicine, 1996, Apr-25, Volume: 334, Issue:17 Topics: Acyl Coenzyme A; Anticholesteremic Agents; Arteriosclerosis; Cerebrovascular Disorders; Controlled Clinical Trials as Topic; Enzyme Inhibitors; Humans; Hypercholesterolemia; Lovastatin; Meta-Analysis as Topic; Oxidoreductases; Pravastatin; Simvastatin	1996
The effect of simvastatin treatment on natural antioxidants in low-density lipoproteins and high-energy phosphates and ubiquinone in skeletal muscle. The American journal of cardiology, 1996, Apr-15, Volume: 77, Issue:10 Topics: Adenosine Triphosphate; Adult; Anticholesteremic Agents; Antioxidants; Cholesterol, LDL; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Muscle, Skeletal; Phosphocreatine; Simvastatin; Ubiquinone	1996
Levels of soluble cell adhesion molecules in patients with dyslipidemia. Circulation, 1996, Apr-01, Volume: 93, Issue:7 Topics: Anticholesteremic Agents; Arteriosclerosis; Atorvastatin; Cell Adhesion Molecules; Colestipol; Drug Therapy, Combination; E-Selectin; Endothelium, Vascular; Enzyme Inhibitors; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertriglyceridemia; Hypolipidemic Agents; Intercellular Adhesion Molecule-1; Lovastatin; Male; Middle Aged; Pyrroles; Risk Factors; Simvastatin; Solubility; Vascular Cell Adhesion Molecule-1	1996
[Current developments in prevention of coronary heart disease]. Zeitschrift fur arztliche Fortbildung, 1996, Volume: 90, Issue:1 Topics: Anticholesteremic Agents; Cholesterol; Cholesterol, Dietary; Coronary Disease; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Randomized Controlled Trials as Topic; Risk Factors; Simvastatin; Survival Rate	1996
Photosensitivity to simvastatin with an unusual response to photopatch and photo tests. Contact dermatitis, 1995, Volume: 33, Issue:4 Topics: Dermatitis, Photoallergic; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lovastatin; Male; Middle Aged; Patch Tests; Simvastatin	1995
[The cholesterol hypothesis has been proved true at last]. Duodecim; laaketieteellinen aikakauskirja, 1995, Volume: 111, Issue:5 Topics: Adult; Aged; Angina Pectoris; Anticholesteremic Agents; Cholesterol; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Myocardial Infarction; Simvastatin	1995
Addressing the spectrum of hypercholesterolemia. Hospital practice (1995), 1996, Jun-15, Volume: 31, Issue:6 Topics: Adult; Aged; Algorithms; Anticholesteremic Agents; Coronary Disease; Diet, Fat-Restricted; Exercise; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Risk Factors; Simvastatin; Smoking Cessation	1996
[Limitations of interventions against hypercholesterolemia]. Atencion primaria, 1996, Mar-15, Volume: 17, Issue:4 Topics: Adult; Age Factors; Anticholesteremic Agents; Cardiovascular Diseases; Cholesterol; Cost-Benefit Analysis; Female; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lovastatin; Male; Middle Aged; Risk Factors; Sex Factors; Simvastatin	1996
Effects of systemic treatment with statins on skin barrier function and stratum corneum water-holding capacity. Dermatology (Basel, Switzerland), 1996, Volume: 192, Issue:3 Topics: Administration, Oral; Adult; Analysis of Variance; Anticholesteremic Agents; Cell Membrane Permeability; Epidermis; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Pravastatin; Simvastatin; Water Loss, Insensible	1996
The effect of manganese-induced hypercholesterolemia on learning in rats. Biological trace element research, 1996, Volume: 51, Issue:3 Topics: Administration, Oral; Animals; Anticholesteremic Agents; Cholesterol; Disease Models, Animal; Female; Hippocampus; Hypercholesterolemia; Lovastatin; Manganese; Manganese Poisoning; Maze Learning; Rats	1996
[Terminal myoglobinuric renal failure in lovastatin therapy with pre-existing chronic renal insufficiency]. Wiener klinische Wochenschrift, 1996, Volume: 108, Issue:11 Topics: Aged; Anticholesteremic Agents; Humans; Hypercholesterolemia; Kidney Failure, Chronic; Kidney Function Tests; Lovastatin; Male; Myoglobinuria; Nephrotic Syndrome; Renal Dialysis	1996
Dermatomyositis with lung involvement in a patient treated with simvastatin. Australian and New Zealand journal of medicine, 1995, Volume: 25, Issue:6 Topics: Aged; Anticholesteremic Agents; Biopsy; Dermatomyositis; Fatal Outcome; Female; Humans; Hypercholesterolemia; Lovastatin; Lung Diseases; Muscle, Skeletal; Simvastatin	1995
Lipid-lowering activity of atorvastatin and lovastatin in rodent species: triglyceride-lowering in rats correlates with efficacy in LDL animal models. Atherosclerosis, 1995, Volume: 117, Issue:2 Topics: Animals; Anticholesteremic Agents; Apolipoproteins B; Atorvastatin; Cholesterol, LDL; Guinea Pigs; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertriglyceridemia; Liver; Lovastatin; Male; Pyrroles; Rabbits; Rats; Rats, Sprague-Dawley; Triglycerides	1995
Cost-effectiveness of cholesterol lowering. Results from the Scandinavian Simvastatin Survival Study (4S) European heart journal, 1996, Volume: 17, Issue:7 Topics: Anticholesteremic Agents; Case-Control Studies; Clinical Trials as Topic; Coronary Disease; Cost of Illness; Cost-Benefit Analysis; Evaluation Studies as Topic; Humans; Hypercholesterolemia; Lovastatin; Prospective Studies; Reproducibility of Results; Scandinavian and Nordic Countries; Simvastatin; Survival Rate	1996
Behavior of Lp(a) and apoproteins (A1, B, C2, C3, E) during and after therapy with simvastatin. Cardiovascular drugs and therapy, 1995, Volume: 9, Issue:6 Topics: Adult; Aged; Anticholesteremic Agents; Apoproteins; Enzyme Inhibitors; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoprotein(a); Lovastatin; Male; Middle Aged; Simvastatin	1995
The statin trials: closing arguments in the case against cholesterol? Scottish medical journal, 1996, Volume: 41, Issue:4 Topics: Anticholesteremic Agents; Coronary Disease; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Risk Factors; Simvastatin	1996
Urinary excretion of mevalonic acid as an indicator of cholesterol synthesis. Journal of lipid research, 1996, Volume: 37, Issue:10 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Cholestyramine Resin; Circadian Rhythm; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Mevalonic Acid; Middle Aged; Pravastatin; Reproducibility of Results; Simvastatin; Xanthomatosis, Cerebrotendinous	1996
Cost effectiveness of lowering cholesterol. Study greatly underestimates the cost effectiveness of statin treatment. BMJ (Clinical research ed.), 1996, Nov-02, Volume: 313, Issue:7065 Topics: Cardiovascular Diseases; Cost-Benefit Analysis; Drug Costs; Humans; Hypercholesterolemia; Lovastatin; Risk Factors; Simvastatin	1996
Cost effectiveness of lowering cholesterol. Statin treatment should be started early. BMJ (Clinical research ed.), 1996, Nov-02, Volume: 313, Issue:7065 Topics: Cardiovascular Diseases; Cost-Benefit Analysis; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hypercholesterolemia; Indoles; Lovastatin; Pravastatin; Simvastatin	1996
Myoglobinuric renal failure due to long-standing lovastatin therapy in a patient with pre-existing chronic renal insufficiency. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1996, Volume: 11, Issue:10 Topics: Acute Kidney Injury; Aged; Anticholesteremic Agents; Enzyme Inhibitors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Kidney Failure, Chronic; Lovastatin; Male; Myoglobinuria; Rhabdomyolysis	1996
Beneficial effects of statins. Lancet (London, England), 1996, Dec-07, Volume: 348, Issue:9041 Topics: Anticholesteremic Agents; Fibrinogen; Humans; Hypercholesterolemia; Lovastatin; Platelet Aggregation; Pravastatin; Simvastatin	1996
[Effect of hypercholesteremia on vascular endothelial function and albumin excretion rate in patients with diabetes mellitus]. Nihon Jinzo Gakkai shi, 1996, Volume: 38, Issue:11 Topics: Albuminuria; Anticholesteremic Agents; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin; Tissue Plasminogen Activator; von Willebrand Factor	1996
Effects of simvastatin on the number and composition of apoproteinB-containing lipoproteins in hypercholesterolemia: analysis of apoproteinB in each lipoprotein fraction by highly sensitive latex method. Endocrine journal, 1996, Volume: 43, Issue:5 Topics: Adult; Aged; Apolipoproteins B; Cholesterol; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Latex Fixation Tests; Lipoproteins; Lovastatin; Male; Middle Aged; Sensitivity and Specificity; Simvastatin; Triglycerides; Ultracentrifugation	1996
Simvastatin increases plasma NO2- and NO3- levels in patients with hypercholesterolemia. Atherosclerosis, 1996, Nov-15, Volume: 127, Issue:1 Topics: Administration, Oral; Anticholesteremic Agents; Cholesterol, LDL; Cholesterol, VLDL; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Nitrates; Nitrites; Simvastatin; Ultracentrifugation	1996
Cost effectiveness of simvastatin treatment to lower cholesterol levels in patients with coronary heart disease. Scandinavian Simvastatin Survival Study Group. The New England journal of medicine, 1997, Jan-30, Volume: 336, Issue:5 Topics: Adult; Age Factors; Aged; Anticholesteremic Agents; Cholesterol; Clinical Trials as Topic; Coronary Disease; Cost of Illness; Cost-Benefit Analysis; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Markov Chains; Middle Aged; Proportional Hazards Models; Sex Factors; Simvastatin; Value of Life	1997
[Increase of myocardial perfusion during antilipemic treatment in patients with ischemic cardiopathy]. Revista espanola de cardiologia, 1996, Volume: 49, Issue:9 Topics: Adult; Aged; Anticholesteremic Agents; Coronary Circulation; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Myocardial Ischemia; Pilot Projects; Simvastatin; Tomography, Emission-Computed, Single-Photon	1996
Effects of initial BMI and on-treatment weight change on the lipid-lowering efficacy of fibrates. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1997, Volume: 21, Issue:2 Topics: Body Mass Index; Clofibric Acid; Female; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lipids; Lovastatin; Male; Middle Aged; Prospective Studies; Sex Factors; Simvastatin; Weight Loss	1997
[The characteristics of the hypolipidemic effect of Mevacor with its permanent multiyear use]. Terapevticheskii arkhiv, 1996, Volume: 68, Issue:12 Topics: Adult; Aged; Child; Diseases in Twins; Dose-Response Relationship, Drug; Drug Evaluation; Female; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Hypolipidemic Agents; Lipids; Lovastatin; Male; Middle Aged; Time Factors	1996
Reversal of cyclosporine-inhibited low-density lipoprotein receptor activity in HepG2 cells by 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors. Hepatology (Baltimore, Md.), 1997, Volume: 25, Issue:4 Topics: Anticholesteremic Agents; Biological Transport, Active; Cyclosporine; Down-Regulation; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lipoproteins, LDL; Lovastatin; Receptors, LDL; Tumor Cells, Cultured; Up-Regulation	1997
Recent developments in coronary heart disease prevention: the Scandinavian and west of Scotland studies. Tennessee medicine : journal of the Tennessee Medical Association, 1997, Volume: 90, Issue:5 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol, LDL; Coronary Disease; Enzyme Inhibitors; Female; Finland; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Morbidity; Pravastatin; Randomized Controlled Trials as Topic; Risk Factors; Scotland; Simvastatin	1997
[Lowering LDL cholesterol with Simvastatin. Also, economically reasonable!]. Der Internist, 1995, Volume: 36, Issue:8 Suppl Topics: Anticholesteremic Agents; Cholesterol, LDL; Drug Costs; Humans; Hypercholesterolemia; Lovastatin; Simvastatin	1995
Beneficial effect of lovastatin on sphincter of Oddi dyskinesia in hypercholesterolemia and hypertriglyceridemia. The American journal of gastroenterology, 1997, Volume: 92, Issue:5 Topics: Aged; Anticholesteremic Agents; Bile Duct Diseases; Female; Humans; Hypercholesterolemia; Hypertriglyceridemia; Lovastatin; Movement Disorders; Sphincter of Oddi	1997
The clinical therapeutic implications of the Scandinavian Simvastatin Survival Study. The American journal of cardiology, 1997, May-15, Volume: 79, Issue:10 Topics: Anticholesteremic Agents; Coronary Disease; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Simvastatin	1997
Polymyositis associated with simvastatin. Lancet (London, England), 1997, May-31, Volume: 349, Issue:9065 Topics: Adult; Anticholesteremic Agents; Humans; Hypercholesterolemia; Lovastatin; Male; Methylprednisolone; Polymyositis; Simvastatin	1997
The use of alternate-day lovastatin in hypercholesterolemic men. The Annals of pharmacotherapy, 1997, Volume: 31, Issue:6 Topics: Aged; Anticholesteremic Agents; Cholesterol, HDL; Cholesterol, LDL; Drug Administration Schedule; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Retrospective Studies; Treatment Outcome; Triglycerides	1997
Prevention of atherosclerosis in coronary-artery bypass grafts. The New England journal of medicine, 1997, Jun-19, Volume: 336, Issue:25 Topics: Cholesterol, LDL; Coronary Artery Bypass; Coronary Artery Disease; Cost-Benefit Analysis; Humans; Hypercholesterolemia; Lovastatin; Recurrence; Saphenous Vein	1997
Simvastatin reduces forearm vascular responsiveness to norepinephrine. Atherosclerosis, 1997, Volume: 131, Issue:2 Topics: Anticholesteremic Agents; Brachial Artery; Cholesterol; Endothelium, Vascular; Follow-Up Studies; Forearm; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Norepinephrine; Simvastatin; Vasoconstriction; Vasoconstrictor Agents	1997
Simvastatin-induced myopathy in a patient treated for hypercholesterolemia. Morphological aspects. Polish journal of pathology : official journal of the Polish Society of Pathologists, 1997, Volume: 48, Issue:1 Topics: Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Muscle, Skeletal; Muscular Diseases; Simvastatin	1997
Results of recent large cholesterol-lowering trials and implications for clinical management. The American journal of cardiology, 1997, Jun-15, Volume: 79, Issue:12 Topics: Anticholesteremic Agents; Cholesterol, LDL; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Randomized Controlled Trials as Topic; Simvastatin	1997
Simvastatin in the secondary prevention of coronary heart disease. Pharmacological research, 1997, Volume: 35, Issue:3 Topics: Anticholesteremic Agents; Coronary Disease; Humans; Hypercholesterolemia; Lovastatin; Simvastatin	1997
The 4S study: a critical review. Pharmacological research, 1997, Volume: 35, Issue:3 Topics: Anticholesteremic Agents; Cholesterol; Coronary Disease; Humans; Hypercholesterolemia; Lovastatin; Simvastatin	1997
The 4S study: a critical review. Pharmacological research, 1997, Volume: 35, Issue:3 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Coronary Disease; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Randomized Controlled Trials as Topic; Simvastatin	1997
The effect of Simvastatin on the plasma antioxidant concentrations in patients with hypercholesterolaemia. Clinica chimica acta; international journal of clinical chemistry, 1997, Jul-04, Volume: 263, Issue:1 Topics: Adult; Anticholesteremic Agents; Antioxidants; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Coenzymes; Enzyme Inhibitors; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lipid Peroxidation; Lovastatin; Male; Middle Aged; Simvastatin; Ubiquinone; Vitamin E	1997
Dietary L-arginine reduces the progression of atherosclerosis in cholesterol-fed rabbits: comparison with lovastatin. Circulation, 1997, Aug-19, Volume: 96, Issue:4 Topics: Animals; Anticholesteremic Agents; Arginine; Arteriosclerosis; Cholesterol; Cholesterol, Dietary; Cyclic GMP; Diet, Atherogenic; Endothelium, Vascular; Hypercholesterolemia; Lovastatin; Male; Nitrates; Nitric Oxide; Rabbits; Superoxides	1997
[Data on cholesterol level screening of patients with ischemic heart disease in the light of the Scandinavian Simvastatin Survival Study]. Orvosi hetilap, 1997, Jun-29, Volume: 138, Issue:26 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Death, Sudden, Cardiac; Drug Costs; Female; Humans; Hungary; Hypercholesterolemia; Lovastatin; Male; Mass Screening; Middle Aged; Myocardial Ischemia; Prevalence; Risk Factors; Scandinavian and Nordic Countries; Simvastatin; Survival Rate	1997
[The mechanism of action of hypolipidemic drugs]. Revue medicale de Liege, 1997, Volume: 52, Issue:6 Topics: Adipose Tissue; Anticholesteremic Agents; Cholesterol, LDL; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl CoA Reductases; Hypercholesterolemia; Hypolipidemic Agents; Indoles; Lipase; Lipid Peroxidation; Lipoproteins, VLDL; Liver; Lovastatin; Microbodies; Nuclear Proteins; Pravastatin; Receptors, Cytoplasmic and Nuclear; Receptors, LDL; Simvastatin; Transcription Factors	1997
Petechial eruptions due to simvastatin in a patient with diabetes mellitus and liver cirrhosis. The Journal of dermatology, 1997, Volume: 24, Issue:8 Topics: Anticholesteremic Agents; Biopsy, Needle; Diabetes Mellitus, Type 1; Humans; Hypercholesterolemia; Japan; Liver Cirrhosis; Lovastatin; Male; Middle Aged; Purpura; Simvastatin	1997
HMG-CoA reductase inhibitors reduce stroke risk, total mortality. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1997, Oct-01, Volume: 54, Issue:19 Topics: Cerebrovascular Disorders; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Meta-Analysis as Topic; Mortality; Pravastatin; Simvastatin	1997
Rhabdomyolysis, acute renal failure and hepatopathy induced by lovastatin monotherapy. Japanese heart journal, 1997, Volume: 38, Issue:4 Topics: Acute Kidney Injury; Anticholesteremic Agents; Chemical and Drug Induced Liver Injury; Female; Humans; Hypercholesterolemia; Lovastatin; Middle Aged; Rhabdomyolysis	1997
HMG-CoA reductase inhibitors decrease CD11b expression and CD11b-dependent adhesion of monocytes to endothelium and reduce increased adhesiveness of monocytes isolated from patients with hypercholesterolemia. Journal of the American College of Cardiology, 1997, Nov-01, Volume: 30, Issue:5 Topics: Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Fluorescent Antibody Technique; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Macrophage-1 Antigen; Male; Monocytes; Simvastatin	1997
Lack of left ventricular dysfunction associated with sustained exposure to hyperlipidemia following lung transplantation. Chest, 1997, Volume: 112, Issue:4 Topics: Anticholesteremic Agents; Arteriosclerosis; Cholesterol; Cholestyramine Resin; Echocardiography; Female; Follow-Up Studies; Gemfibrozil; Humans; Hypercholesterolemia; Hyperlipidemias; Hyperlipoproteinemias; Hypertriglyceridemia; Hypolipidemic Agents; Immunosuppressive Agents; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Lovastatin; Lung Transplantation; Male; Middle Aged; Myocardial Ischemia; Probucol; Radionuclide Angiography; Retrospective Studies; Triglycerides; Ventricular Dysfunction, Left; Ventricular Function, Left	1997
Interactions of platelets, macrophages, and lipoproteins in hypercholesterolemia: antiatherogenic effects of HMG-CoA reductase inhibitor therapy. Journal of cardiovascular pharmacology, 1998, Volume: 31, Issue:1 Topics: Adult; Aged; Animals; Anticholesteremic Agents; Blood Platelets; Cell Communication; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lipid Peroxidation; Lipoproteins; Lipoproteins, LDL; Lovastatin; Macrophages; Mice; Middle Aged; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors	1998
A retrospective drug utilization evaluation of antihyperlipidaemic agents in a medical centre in Taiwan. Journal of clinical pharmacy and therapeutics, 1997, Volume: 22, Issue:4 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Child; Drug Monitoring; Drug Prescriptions; Drug Utilization; Female; Guidelines as Topic; Humans; Hypercholesterolemia; Insurance, Health; Lovastatin; Male; Middle Aged; Pravastatin; Random Allocation; Retrospective Studies; Taiwan	1997
Lack of interaction of apolipoprotein E phenotype with the lipoprotein response to lovastatin or gemfibrozil in patients with primary hypercholesterolemia. Metabolism: clinical and experimental, 1998, Volume: 47, Issue:5 Topics: Adult; Aged; Anticholesteremic Agents; Apolipoproteins E; Data Interpretation, Statistical; Drug Interactions; Female; Gemfibrozil; Humans; Hypercholesterolemia; Hyperlipidemias; Hypolipidemic Agents; Lipoproteins; Lovastatin; Male; Middle Aged; Phenotype; Polymorphism, Genetic	1998
Reducing expenditures for statin-type lipid-lowering agents. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1998, May-15, Volume: 55, Issue:10 Topics: Cost Control; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipidemias; Hypolipidemic Agents; Lovastatin; Managed Care Programs; United States	1998
Insulin-mediated venodilation is impaired in patients with high cholesterol. Hypertension (Dallas, Tex. : 1979), 1998, Volume: 31, Issue:6 Topics: Adult; Aged; Analysis of Variance; Anticholesteremic Agents; Cholesterol; Cholesterol, LDL; Endothelium, Vascular; Female; Hand; Humans; Hypercholesterolemia; Insulin; Lovastatin; Male; Middle Aged; Nitroprusside; Norepinephrine; Regression Analysis; Ultrasonography; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Veins	1998
Do you need cholesterol-lowering drugs? Health news (Waltham, Mass.), 1998, Jun-25, Volume: 4, Issue:8 Topics: Anticholesteremic Agents; Humans; Hypercholesterolemia; Lovastatin	1998
Comparative dose efficacy study of atorvastatin versus simvastatin, pravastatin, lovastatin, and fluvastatin in patients with hypercholesterolemia (the CURVES study) The American journal of cardiology, 1998, Aug-01, Volume: 82, Issue:3 Topics: Anticholesteremic Agents; Atorvastatin; Cholesterol; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Humans; Hypercholesterolemia; Indoles; Lovastatin; Pravastatin; Pyrroles; Randomized Controlled Trials as Topic; Simvastatin; Treatment Outcome	1998
[Lipid lowering: myth or therapeutic necessity?]. Deutsche medizinische Wochenschrift (1946), 1998, Oct-02, Volume: 123, Issue:40 Suppl Topics: Coronary Disease; Humans; Hypercholesterolemia; Hyperlipidemias; Hypolipidemic Agents; Lipoproteins, HDL; Lipoproteins, LDL; Lovastatin; Pyridines; Risk Factors	1998
Lovastatin maintains nitric oxide--but not EDHF-mediated endothelium-dependent relaxation in the hypercholesterolemic rabbit carotid artery. Atherosclerosis, 1999, Volume: 142, Issue:1 Topics: Acetylcholine; Animals; Anticholesteremic Agents; Biological Factors; Carotid Arteries; Cholesterol; Enzyme Inhibitors; Hypercholesterolemia; In Vitro Techniques; Lovastatin; Male; Nitric Oxide; Nitroarginine; Rabbits; Vasodilation; Vasodilator Agents	1999
"Care," cancer and coenzyme Q10. Journal of the American College of Cardiology, 1999, Volume: 33, Issue:3 Topics: Aging; Biomarkers, Tumor; Breast Neoplasms; Coenzymes; Cytoprotection; Female; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Incidence; Lovastatin; Postmenopause; Ubiquinone	1999
Effects of LY295427, a low-density lipoprotein (LDL) receptor up-regulator, on LDL receptor gene transcription and cholesterol metabolism in normal and hypercholesterolemic hamsters. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:1 Topics: Acetates; Animals; Anticholesteremic Agents; Cholestanols; Cholesterol; Cholesterol, Dietary; Cholesterol, LDL; Coconut Oil; Cocos; Cricetinae; Dietary Fats; Homeostasis; Hypercholesterolemia; Intestinal Absorption; Liver; Lovastatin; Male; Mesocricetus; Plant Oils; Receptors, LDL; RNA, Messenger; Up-Regulation	1999
Immunoadsorption and dextran sulfate cellulose LDL-apheresis for severe hypercholesterolemia: the Rogosin Institute experience 1982-1992. Transfusion science, 1993, Volume: 14, Issue:3 Topics: Adult; Aged; Blood Component Removal; Child; Cholesterol; Cholesterol, LDL; Cholestyramine Resin; Coronary Disease; Dextran Sulfate; Humans; Hypercholesterolemia; Immunosorbent Techniques; Lovastatin; Middle Aged; Niacin; Pilot Projects	1993
Cost-effectiveness of simvastatin versus cholestyramine: results for Sweden. PharmacoEconomics, 1992, Volume: 1, Issue:3 Topics: Adult; Cholestyramine Resin; Coronary Disease; Cost Savings; Cost-Benefit Analysis; Health Care Costs; Humans; Hypercholesterolemia; Life Expectancy; Lovastatin; Male; Middle Aged; Multivariate Analysis; Sweden	1992
By the way, doctor. I have high cholesterol, and have been taking Mevacor (lovastatin) for two years. Recently, I was switched to Pravachol (pravastatin) because my insurance company would no longer pay for Mevacor. Is it as good? Harvard women's health watch, 1999, Volume: 6, Issue:10 Topics: Anticholesteremic Agents; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Pravastatin	1999
L-arginine supplementation in hypercholesterolemic rabbits normalizes leukocyte adhesion to non-endothelial matrix. Life sciences, 2000, Volume: 66, Issue:16 Topics: Animals; Arginine; Cell Adhesion; Hypercholesterolemia; Leukocytes; Lovastatin; Male; Rabbits; Vitamin E	2000
Which statin is most efficient for the treatment of hypercholesterolemia? A cost-effectiveness analysis. Clinical therapeutics, 1999, Volume: 21, Issue:11 Topics: Administration, Oral; Algorithms; Cholesterol, LDL; Cost-Benefit Analysis; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Male; Middle Aged; Models, Economic; Pravastatin; Simvastatin; Treatment Outcome	1999
On call. I am 58 years old. I've always been healthy, but my doctor found that my cholesterol was 279. He prescribed Mevacor, and my cholesterol came down to 210. Do I still need to be on a low-fat diet? Harvard men's health watch, 2000, Volume: 5, Issue:1 Topics: Anticholesteremic Agents; Dietary Fats; Humans; Hypercholesterolemia; Lovastatin	2000
A need to redefine the consensus on the use of statins in coronary heart disease prevention. European heart journal, 2000, Volume: 21, Issue:19 Topics: Anticholesteremic Agents; Cholesterol; Clinical Trials as Topic; Coronary Disease; Humans; Hypercholesterolemia; Lovastatin; Practice Guidelines as Topic; Pravastatin	2000
Development of tachyphylaxis among patients taking HMG CoA reductase inhibitors. The American journal of cardiology, 2000, Nov-15, Volume: 86, Issue:10 Topics: Atorvastatin; Cholesterol, LDL; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Least-Squares Analysis; Linear Models; Lovastatin; Nonlinear Dynamics; Pravastatin; Pyrroles; Retrospective Studies; Simvastatin; Tachyphylaxis; Time Factors	2000
Effect of preoperative statin therapy and cardiac outcomes after coronary artery bypass grafting. The American journal of cardiology, 2000, Nov-15, Volume: 86, Issue:10 Topics: Aged; Anticholesteremic Agents; Arrhythmias, Cardiac; Atorvastatin; Cause of Death; Coronary Artery Bypass; Coronary Disease; Female; Heart Failure; Heptanoic Acids; Humans; Hypercholesterolemia; Incidence; Lovastatin; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Preoperative Care; Pyrroles; Recurrence; Retrospective Studies; Risk Factors; Simvastatin; Stroke; Treatment Outcome	2000
Are statins right for you? Time, 2000, Nov-06, Volume: 156, Issue:19 Topics: Anticholesteremic Agents; Cholesterol; Coronary Disease; Humans; Hypercholesterolemia; Lovastatin; United States	2000
Is a statin a statin? International journal of clinical practice, 2001, Volume: 55, Issue:2 Topics: Anticholesteremic Agents; Humans; Hypercholesterolemia; Lipoproteins, HDL; Lipoproteins, LDL; Lovastatin; Pravastatin; Simvastatin	2001
Statins are magic when you gotta have heart. U.S. news & world report, 2001, Apr-16, Volume: 130, Issue:15 Topics: Anticholesteremic Agents; Cholesterol, HDL; Cholesterol, LDL; Drug Costs; Humans; Hypercholesterolemia; Lovastatin; United States	2001
Statins and dementia. Archives of neurology, 2001, Volume: 58, Issue:7 Topics: Anticholesteremic Agents; Cognition; Cognition Disorders; Dose-Response Relationship, Drug; Humans; Hypercholesterolemia; Lovastatin; Pravastatin; Randomized Controlled Trials as Topic; Selection Bias; Simvastatin	2001
Cholesterol-lowering drugs. Some drugs with demonstrated efficacy but different benefits in primary and secondary prevention. Prescrire international, 1999, Volume: 8, Issue:42 Topics: Anticholesteremic Agents; Bezafibrate; Cholestyramine Resin; Clinical Trials as Topic; Clofibrate; Female; Gemfibrozil; Humans; Hypercholesterolemia; Lovastatin; Male; Myocardial Infarction; Pravastatin; Treatment Outcome	1999
The synergistic hypocholesterolemic activity of the potent cholesterol absorption inhibitor, ezetimibe, in combination with 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors in dogs. Metabolism: clinical and experimental, 2001, Volume: 50, Issue:10 Topics: Animals; Anticholesteremic Agents; Azetidines; Cholesterol; Cholesterol, Dietary; Dogs; Drug Combinations; Drug Synergism; Ezetimibe; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Liver; Lovastatin; Male; Pravastatin; Simvastatin; Time Factors	2001
Naringin has an antiatherogenic effect with the inhibition of intercellular adhesion molecule-1 in hypercholesterolemic rabbits. Journal of cardiovascular pharmacology, 2001, Volume: 38, Issue:6 Topics: Animals; Anticholesteremic Agents; Aorta, Thoracic; Arteriosclerosis; Cholesterol; Cholesterol, HDL; Diet, Atherogenic; Flavanones; Flavonoids; Foam Cells; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Immunohistochemistry; Intercellular Adhesion Molecule-1; Liver; Lovastatin; Male; Rabbits; Time Factors; Triglycerides	2001
3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors reduce human pancreatic cancer cell invasion and metastasis. Gastroenterology, 2002, Volume: 122, Issue:2 Topics: Adenocarcinoma; Animals; Cell Division; Cell Membrane; Cytosol; Epidermal Growth Factor; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Liver Neoplasms, Experimental; Lovastatin; Mice; Mice, Nude; Neoplasm Invasiveness; Pancreatic Neoplasms; rhoA GTP-Binding Protein; Tumor Cells, Cultured	2002
Goals of statin conversion program. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2002, Feb-15, Volume: 59, Issue:4 Topics: Anticholesteremic Agents; Drug Utilization; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Simvastatin	2002
Effects of ML-236B on cholesterol metabolism in mice and rats: lack of hypocholesterolemic activity in normal animals. Biochimica et biophysica acta, 1979, Nov-21, Volume: 575, Issue:2 Topics: Animals; Anticholesteremic Agents; Bile Acids and Salts; Cholesterol; Cholesterol, Dietary; Feces; Hydroxymethylglutaryl CoA Reductases; Hypercholesterolemia; Hyperlipidemias; Liver; Lovastatin; Male; Mice; Naphthalenes; Polyethylene Glycols; Rats; Species Specificity; Sterols	1979
[Effect of lovastatin on platelet function in hypercholesterolemic patients]. Polskie Archiwum Medycyny Wewnetrznej, 1992, Volume: 88, Issue:5 Topics: Adult; Aged; Blood Platelets; Cholesterol, HDL; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Platelet Aggregation	1992
Long-term therapy with high-dose simvastatin does not affect adrenocortical and gonadal hormones in hypercholesterolemic patients. Metabolism: clinical and experimental, 1992, Volume: 41, Issue:2 Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anticholesteremic Agents; Apolipoprotein A-I; Apolipoproteins B; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Estradiol; Female; Follicle Stimulating Hormone; Follow-Up Studies; Humans; Hypercholesterolemia; Lovastatin; Luteinizing Hormone; Male; Middle Aged; Progesterone; Simvastatin; Testosterone; Triglycerides	1992
An overview: long-term tolerability of lovastatin and simvastatin. Zhonghua yi xue za zhi = Chinese medical journal; Free China ed, 1992, Volume: 49, Issue:2 Topics: Anticholesteremic Agents; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin	1992
Cholesterol inhibition, cancer, and chemotherapy. Lancet (London, England), 1992, May-09, Volume: 339, Issue:8802 Topics: Adjuvants, Pharmaceutic; Animals; Antineoplastic Agents; Cholesterol; Dogs; Drug Evaluation, Preclinical; Humans; Hydroxymethylglutaryl CoA Reductases; Hypercholesterolemia; Lovastatin; Mevalonic Acid; Mice; Neoplasms; Neoplasms, Experimental; Rats	1992
Simvastatin use in children. Lancet (London, England), 1992, Jun-13, Volume: 339, Issue:8807 Topics: Adolescent; Anticholesteremic Agents; Child; Child, Preschool; Humans; Hypercholesterolemia; Lovastatin; Simvastatin	1992
Treatment of hypercholesterolaemia in children. Lancet (London, England), 1992, Aug-29, Volume: 340, Issue:8818 Topics: Child; Cholestyramine Resin; Female; Humans; Hypercholesterolemia; Lovastatin; Male	1992
Effect of simvastatin in CAPD patients with hypercholesterolemia. Advances in peritoneal dialysis. Conference on Peritoneal Dialysis, 1992, Volume: 8 Topics: Anticholesteremic Agents; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Simvastatin	1992
Lovastatin in the treatment of hypercholesterolemia in CAPD. Advances in peritoneal dialysis. Conference on Peritoneal Dialysis, 1992, Volume: 8 Topics: Adult; Aged; Female; Humans; Hypercholesterolemia; Lovastatin; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory	1992
Effect of lovastatin on hypercholesterolemia in chronic renal failure. Advances in peritoneal dialysis. Conference on Peritoneal Dialysis, 1992, Volume: 8 Topics: Animals; Blood Urea Nitrogen; Cholesterol; Hydroxymethylglutaryl CoA Reductases; Hypercholesterolemia; Kidney Failure, Chronic; Lovastatin; Mice; Mice, Inbred C57BL	1992
The cholesterol controversy. BMJ (Clinical research ed.), 1992, Apr-04, Volume: 304, Issue:6831 Topics: Coronary Disease; Humans; Hypercholesterolemia; Lovastatin	1992
Using changes in attributable risk to predict long-term efficacy of simvastatin treatment. Clinical chemistry, 1992, Volume: 38, Issue:10 Topics: Adult; Anticholesteremic Agents; Cholesterol; Coronary Disease; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Risk Factors; Simvastatin	1992
[The effect of lovastatin in the treatment of primary hypercholesterolemia]. Zhonghua nei ke za zhi, 1992, Volume: 31, Issue:1 Topics: Adult; Aged; Apolipoproteins B; Child; Cholesterol; Cholesterol, LDL; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged	1992
[Effects of lovastatin (mevacor) on platelet function in hypercholesterolemia in patients with ischemic heart disease]. Kardiologiia, 1992, Volume: 32, Issue:6 Topics: Adult; Blood Platelets; Cholesterol; Coronary Disease; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Platelet Aggregation; Time Factors	1992
3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor simvastatin and the human lens. Clinical results of a 3-year follow-up. Arzneimittel-Forschung, 1992, Volume: 42, Issue:8 Topics: Adult; Aged; Cataract; Cholesterol; Cholesterol, HDL; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lens, Crystalline; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides	1992
Efficacy and tolerability of medium-term treatment with simvastatin in primary hypercholesterolaemia. International journal of clinical pharmacology research, 1992, Volume: 12, Issue:2 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Cholesterol, LDL; Enzymes; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides	1992
3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 9. The synthesis and biological evaluation of novel simvastatin analogs. Journal of medicinal chemistry, 1992, Oct-16, Volume: 35, Issue:21 Topics: Administration, Oral; Animals; Anticholesteremic Agents; Disease Models, Animal; Dogs; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Magnetic Resonance Spectroscopy; Rats; Simvastatin; Structure-Activity Relationship	1992
Effect of simvastatin on qualitative and quantitative changes of lipoprotein metabolism in CAPD patients. Nephron, 1992, Volume: 62, Issue:1 Topics: Adult; Aged; Cholesterol; Cholesterol, LDL; Cholesterol, VLDL; Dose-Response Relationship, Drug; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoproteins; Lovastatin; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Radioimmunoassay; Simvastatin	1992
Subcutaneous administration of HMG-CoA reductase inhibitors in hyperlipidaemic and normal rats. Laboratory animals, 1992, Volume: 26, Issue:4 Topics: Administration, Oral; Animals; Anticholesteremic Agents; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Infusion Pumps, Implantable; Injections, Subcutaneous; Lovastatin; Pravastatin; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Simvastatin	1992
Effect of lovastatin on lipoprotein fluidity in patients with hypercholesterolaemia. Scandinavian journal of clinical and laboratory investigation, 1992, Volume: 52, Issue:7 Topics: Adult; Aged; Chemical Phenomena; Chemistry, Physical; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Diphenylhexatriene; Female; Fluorescence Polarization; Humans; Hypercholesterolemia; Lipoproteins; Lovastatin; Male; Middle Aged; Temperature	1992
Reduction of plasma cholesterol by lovastatin normalizes erythrocyte membrane fluidity in patients with severe hypercholesterolaemia. British journal of clinical pharmacology, 1992, Volume: 34, Issue:5 Topics: Adult; Aged; Cholesterol; Cholesterol, LDL; Erythrocyte Deformability; Erythrocyte Membrane; Female; Humans; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged	1992
Possible mechanism and treatment of o,p'DDD-induced hypercholesterolaemia. The Quarterly journal of medicine, 1992, Volume: 84, Issue:305 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Cushing Syndrome; Cytochrome P-450 Enzyme System; Female; Humans; Hypercholesterolemia; Lipids; Lovastatin; Male; Mevalonic Acid; Middle Aged; Mitotane; Simvastatin	1992
Influence of age and gender on the plasma profiles of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitory activity following multiple doses of lovastatin and simvastatin. Pharmaceutical research, 1992, Volume: 9, Issue:12 Topics: Adult; Aged; Aging; Female; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Sex Characteristics; Simvastatin	1992
[Mid-term clinical study of the effectiveness of and tolerability to simvastatin ++ in dyslipidemic patients]. Minerva medica, 1992, Volume: 83, Issue:12 Topics: Adult; Aged; Cholesterol; Female; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides	1992
[Diabetes mellitus, hypercholesterolemia, and therapeutic prospects with simvastatin. General considerations and personal contribution]. Minerva medica, 1992, Volume: 83, Issue:12 Topics: Adult; Anticholesteremic Agents; Cholesterol; Diabetes Mellitus, Type 2; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides	1992
Lupuslike syndrome associated with simvastatin. Archives of internal medicine, 1992, Volume: 152, Issue:5 Topics: Aged; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Lupus Erythematosus, Systemic; Simvastatin	1992
Short- and long-term effects of lovastatin and pravastatin alone and in combination with cholestyramine on serum lipids, lipoproteins and apolipoproteins in primary hypercholesterolaemia. European journal of clinical pharmacology, 1992, Volume: 42, Issue:4 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Apolipoproteins; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Cholestyramine Resin; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Lipids; Lipoproteins; Lovastatin; Male; Middle Aged; Pravastatin; Time Factors; Triglycerides	1992
[Simvastatin-induced hepatitis]. Gastroenterologie clinique et biologique, 1992, Volume: 16, Issue:1 Topics: Anticholesteremic Agents; Chemical and Drug Induced Liver Injury; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin	1992
Clinical investigation on the hypolipidemic effect of simvastatin in primary hypercholesterolemia. La Clinica terapeutica, 1992, Volume: 140, Issue:1 Pt 2 Topics: Anticholesteremic Agents; Capsules; Drug Evaluation; Fasting; Humans; Hypercholesterolemia; Lipids; Lovastatin; Simvastatin; Time Factors	1992
Lovastatin-induced hepatitis. Israel journal of medical sciences, 1992, Volume: 28, Issue:2 Topics: Chemical and Drug Induced Liver Injury; Female; Humans; Hypercholesterolemia; Lovastatin; Middle Aged	1992
Cataracts by lipid lowering drugs? Three different HMG-CoA reductase inhibitors studied in hypercholesterolemic rabbits. Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1992, Volume: 192, Issue:1 Topics: Animals; Anticholesteremic Agents; Cataract; Cholesterol; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lovastatin; Pravastatin; Rabbits; Simvastatin	1992
Increased thromboxane biosynthesis in type IIa hypercholesterolemia. Circulation, 1992, Volume: 85, Issue:5 Topics: Adult; Aged; Anticholesteremic Agents; Aspirin; Blood Platelets; Dose-Response Relationship, Drug; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin; Thromboxane A2	1992
Pravastatin, simvastatin, and lovastatin for lowering serum cholesterol concentrations. The Medical letter on drugs and therapeutics, 1992, Jun-12, Volume: 34, Issue:872 Topics: Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Pravastatin; Simvastatin	1992
[Simvastatin in the treatment of hypercholesterolemia in the aged. An epidemiological and clinical study]. Minerva medica, 1992, Volume: 83, Issue:6 Topics: Adult; Age Factors; Aged; Anticholesteremic Agents; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Risk Factors; Simvastatin; Time Factors; Triglycerides	1992
Lovastatin in the treatment of hypercholesterolemia in nephrotic syndrome due to diabetic nephropathy stage IV-V. Clinical nephrology, 1992, Volume: 37, Issue:6 Topics: Adult; Aged; Cholesterol; Creatinine; Diabetic Nephropathies; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Nephrotic Syndrome; Triglycerides	1992
Interaction between fibre and lovastatin. Lancet (London, England), 1991, Sep-14, Volume: 338, Issue:8768 Topics: Cholesterol, LDL; Dietary Fiber; Drug Interactions; Female; Humans; Hypercholesterolemia; Lovastatin; Middle Aged; Pectins	1991
Simvastatin and side effects. The New Zealand medical journal, 1991, Nov-27, Volume: 104, Issue:924 Topics: Adult; Aged; Anticholesteremic Agents; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin; Surveys and Questionnaires	1991
[Quality of treatment in hypercholesterolemia in ambulatory patients]. Schweizerische medizinische Wochenschrift, 1991, Dec-07, Volume: 121, Issue:49 Topics: Adult; Anticholesteremic Agents; Cholesterol, Dietary; Cohort Studies; Decision Making; Female; Humans; Hypercholesterolemia; Long-Term Care; Lovastatin; Male; Middle Aged; Simvastatin	1991
[Simvastatin-induced acute pancreatitis: two cases]. Gastroenterologie clinique et biologique, 1991, Volume: 15, Issue:12 Topics: Acute Disease; Adult; Aged; Anticholesteremic Agents; Humans; Hypercholesterolemia; Lovastatin; Male; Pancreatitis; Simvastatin	1991
[A new case of simvastatin-induced acute pancreatitis]. Gastroenterologie clinique et biologique, 1991, Volume: 15, Issue:12 Topics: Acute Disease; Anticholesteremic Agents; Female; Humans; Hypercholesterolemia; Lovastatin; Middle Aged; Pancreatitis; Simvastatin	1991
Response to cholesterol-lowering drugs in familial defective apolipoprotein B-100. Atherosclerosis, 1991, Volume: 91, Issue:1-2 Topics: Adult; Aged; Anticholesteremic Agents; Apolipoprotein B-100; Apolipoproteins B; Apolipoproteins E; Cholesterol; Cholesterol, LDL; Cholestyramine Resin; Drug Therapy, Combination; Female; Heterozygote; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Phenotype; Simvastatin; Triglycerides	1991
Effect of lovastatin on intimal hyperplasia after balloon angioplasty: a study in an atherosclerotic hypercholesterolemic rabbit. Journal of the American College of Cardiology, 1991, Volume: 17, Issue:1 Topics: Angioplasty, Balloon; Animals; Arteriosclerosis; Femoral Artery; Hypercholesterolemia; Hyperplasia; Lovastatin; Male; Muscle, Smooth, Vascular; Rabbits; Recurrence	1991
[Simvastatin in the treatment of hypercholesterolemia]. La Clinica terapeutica, 1991, Jun-15, Volume: 137, Issue:5 Topics: Aged; Anticholesteremic Agents; Blood Pressure; Cholesterol; Drug Evaluation; Eye; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides	1991
[Personal experience with lovastatin, a HMG-CoA reductase inhibitor (Mevacor, MSD) in the treatment of hypercholesterolemia]. Vnitrni lekarstvi, 1991, Volume: 37, Issue:5 Topics: Female; Humans; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged	1991
Hypercholesterolemia: new findings and clinical applications. Introduction. The American journal of medicine, 1991, Jul-31, Volume: 91, Issue:1B Topics: Cholesterol, LDL; Humans; Hypercholesterolemia; Lovastatin; Triparanol	1991
Hypercholesterolemia: new findings and clinical applications. Proceedings of a symposium. April 25, 1990, Chicago, Illinois. The American journal of medicine, 1991, Jul-31, Volume: 91, Issue:1B Topics: Humans; Hypercholesterolemia; Lovastatin	1991
Effect of simvastatin treatment on the dyslipoproteinemia in CAPD patients. Atherosclerosis, 1991, Volume: 86, Issue:2-3 Topics: Adult; Aged; Apolipoproteins; Cholesterol; Female; Humans; Hydroxymethylglutaryl CoA Reductases; Hypercholesterolemia; Lipoproteins; Lovastatin; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Simvastatin; Triglycerides	1991
Cost-effectiveness of HMG-CoA reductase inhibition for primary and secondary prevention of coronary heart disease. JAMA, 1991, Mar-06, Volume: 265, Issue:9 Topics: Adult; Aged; Aged, 80 and over; Cholesterol; Coronary Disease; Cost-Benefit Analysis; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Primary Prevention; Sensitivity and Specificity	1991
Pravastatin and simvastatin for hypercholesterolemia. The Medical letter on drugs and therapeutics, 1991, Mar-08, Volume: 33, Issue:839 Topics: Anticholesteremic Agents; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Drug Therapy, Combination; Heptanoic Acids; Humans; Hypercholesterolemia; Lovastatin; Muscular Diseases; Naphthalenes; Pravastatin; Simvastatin	1991
An economic evaluation of lovastatin for cholesterol lowering and coronary artery disease reduction. The American journal of cardiology, 1991, Apr-15, Volume: 67, Issue:9 Topics: Adult; Age Factors; Cholesterol; Coronary Disease; Cost-Benefit Analysis; Costs and Cost Analysis; Disability Evaluation; Evaluation Studies as Topic; Fees, Medical; Female; Humans; Hypercholesterolemia; Life Expectancy; Lovastatin; Male; Middle Aged; Risk Factors; Sensitivity and Specificity; Smoking; Value of Life	1991
Hypercholesterolaemia: simvastatin and pravastatin alter cholesterol metabolism by different mechanisms. Biochimica et biophysica acta, 1991, Apr-03, Volume: 1082, Issue:3 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent; Hypercholesterolemia; Leukocytes; Lovastatin; Middle Aged; Naphthalenes; Pravastatin; Simvastatin	1991
[Cost-effectiveness of lowering of blood cholesterol using simvastatin and cholestyramine]. Nederlands tijdschrift voor geneeskunde, 1991, Apr-13, Volume: 135, Issue:15 Topics: Adult; Age Factors; Anticholesteremic Agents; Cholestyramine Resin; Cost-Benefit Analysis; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Netherlands; Sex Factors; Simvastatin	1991
Comparison of different HMG-CoA reductase inhibitors. European journal of clinical pharmacology, 1991, Volume: 40 Suppl 1 Topics: Anticholesteremic Agents; Apolipoproteins; Cholesterol, HDL; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Naphthalenes; Pravastatin; Simvastatin; Triglycerides	1991
Simvastatin. The Australian nurses' journal. Royal Australian Nursing Federation, 1991, Volume: 21, Issue:1 Topics: Anticholesteremic Agents; Contraindications; Drug Interactions; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Pregnancy; Simvastatin	1991
[Lovastatin in the treatment of primary hypercholesterolemia]. Kardiologia polska, 1991, Volume: 35, Issue:8 Topics: Adult; Aged; Apolipoproteins B; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lipoproteins; Lovastatin; Male; Middle Aged; Triglycerides	1991
Effect of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibition on human gut mucosa. Lipids, 1991, Volume: 26, Issue:7 Topics: Anticholesteremic Agents; Cell Division; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intestinal Mucosa; Jejunum; Lovastatin; Male; Middle Aged; Mitotic Index; Simvastatin	1991
Cholesterol-lowering effects of a 10 mg daily dose of lovastatin in patients with initial total cholesterol levels 200 to 240 mg/dl (5.18 to 6.21 mmol/liter). The American journal of cardiology, 1991, Nov-01, Volume: 68, Issue:11 Topics: Cholesterol; Cholesterol, LDL; Coronary Disease; Drug Administration Schedule; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Risk Factors	1991
Proteinuria as complication of simvastatin treatment. Lancet (London, England), 1990, Dec-08, Volume: 336, Issue:8728 Topics: Albuminuria; Anticholesteremic Agents; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Proteinuria; Simvastatin; Transferrin	1990
Cholesterol-lowering simvastatin achieves listing as a pharmaceutical benefit. The Medical journal of Australia, 1991, Mar-18, Volume: 154, Issue:6 Topics: Adult; Anticholesteremic Agents; Humans; Hypercholesterolemia; Lovastatin; Middle Aged; Pharmacopoeias as Topic; Simvastatin	1991
[Simvastatin: a new drug responsible for acute pancreatitis?]. Gastroenterologie clinique et biologique, 1991, Volume: 15, Issue:1 Topics: Acute Disease; Anticholesteremic Agents; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Pancreatitis; Simvastatin	1991
Lovastatin and nephrotic syndrome. Southern medical journal, 1991, Volume: 84, Issue:4 Topics: Adult; Humans; Hypercholesterolemia; Lovastatin; Male; Nephrotic Syndrome; Recurrence; Remission Induction	1991
Low density lipoprotein density and composition in hypercholesterolaemic men treated with HMG CoA reductase inhibitors and gemfibrozil. Journal of internal medicine, 1991, Volume: 229, Issue:5 Topics: Adult; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lipoproteins, LDL; Lovastatin; Male; Middle Aged; Simvastatin	1991
[The problem of hypercholesterolemia in the aged]. Minerva cardioangiologica, 1990, Volume: 38, Issue:10 Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anticholesteremic Agents; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin	1990
No lens changes caused by simvastatin results from a prospective drug safety study. Lens and eye toxicity research, 1990, Volume: 7, Issue:3-4 Topics: Adult; Aged; Cataract; Drug Evaluation; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intraocular Pressure; Lens, Crystalline; Lovastatin; Male; Middle Aged; Photography; Prospective Studies; Simvastatin; Visual Acuity	1990
Silent myocardial ischemia--classification and management. Hospital practice (Office ed.), 1990, Feb-28, Volume: 25, Issue:2A Topics: Angina Pectoris; Atenolol; Drug Therapy, Combination; Heart Function Tests; Hemodynamics; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Myocardial Infarction; Nifedipine; Risk Factors	1990
Comparative effects of simvastatin (MK-733) and pravastatin (CS-514) on hypercholesterolemia induced by cholesterol feeding in rabbits. Biochimica et biophysica acta, 1990, Feb-23, Volume: 1042, Issue:3 Topics: Animals; Bile; Cholesterol; Cholesterol, Dietary; Heptanoic Acids; Hypercholesterolemia; Lipoproteins; Lipoproteins, LDL; Lovastatin; Male; Microsomes, Liver; Naphthalenes; Pravastatin; Rabbits; Receptors, LDL; Simvastatin; Statistics as Topic; Sterol O-Acyltransferase	1990
Effects of long-term treatment with simvastatin on plasma lipids and lipoproteins in patients with primary hypercholesterolemia. Klinische Wochenschrift, 1990, Aug-17, Volume: 68, Issue:16 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lipids; Lipoproteins; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides	1990
Effects of lovastatin in diabetic patients treated with chlorpropamide. Clinical pharmacology and therapeutics, 1990, Volume: 48, Issue:4 Topics: Acyl Coenzyme A; Administration, Oral; Apolipoproteins B; Blood Glucose; Chlorpropamide; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Female; Humans; Hypercholesterolemia; Lipoproteins, VLDL; Lovastatin; Male; Middle Aged; Time Factors	1990
Lovastatin. Warfarin interaction. Archives of internal medicine, 1990, Volume: 150, Issue:11 Topics: Atrial Fibrillation; Drug Interactions; Epistaxis; Gastrointestinal Hemorrhage; Hematuria; Humans; Hypercholesterolemia; Hypoprothrombinemias; Intracranial Embolism and Thrombosis; Lovastatin; Male; Middle Aged; Warfarin	1990
[The effects of the cholesterol synthesis inhibitor simvastatin in patients with hypercholesterolemia with and without diabetes mellitus]. Nederlands tijdschrift voor geneeskunde, 1990, Nov-03, Volume: 134, Issue:44 Topics: Anticholesteremic Agents; Cholesterol; Diabetes Complications; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin	1990
Lovastatin decreases coenzyme Q levels in humans. Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:22 Topics: Adolescent; Cardiac Output; Coronary Disease; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Myocardial Contraction; Stroke Volume; Ubiquinone	1990
Effects of therapy with diet and simvastatin on atherosclerosis in hypercholesterolemic patients. Cardiovascular drugs and therapy, 1990, Volume: 4, Issue:5 Topics: Adult; Aged; Anticholesteremic Agents; Combined Modality Therapy; Coronary Angiography; Coronary Artery Disease; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin	1990
[Lovastatin. A new drug for the treatment of hypercholesterolemia]. Revista medica de Panama, 1990, Volume: 15, Issue:3 Topics: Adult; Aged; Cholesterol; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged	1990
[New perspectives in the control of hypercholesterolemia with the use of HMG CoA reductase inhibitors]. Arquivos brasileiros de cardiologia, 1990, Volume: 54, Issue:3 Topics: Cholesterol; Cholesterol, LDL; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lovastatin	1990
[Simvastatin (MK-733), a new HMG-CoA reductase inhibitor, in the treatment of hypercholesterolemia in elderly patients with atherosclerosis]. Arquivos brasileiros de cardiologia, 1990, Volume: 54, Issue:6 Topics: Aged; Alanine Transaminase; Arteriosclerosis; Cholesterol; Cholesterol, LDL; Creatine Kinase; Female; Humans; Hydroxymethylglutaryl CoA Reductases; Hypercholesterolemia; Lipids; Lovastatin; Male; Simvastatin	1990
Lovastatin ameliorates the development of glomerulosclerosis and uremia in experimental nephrotic syndrome. American journal of kidney diseases : the official journal of the National Kidney Foundation, 1990, Volume: 15, Issue:1 Topics: Animals; Blood Urea Nitrogen; Cholesterol; Female; Glomerulonephritis; Glomerulosclerosis, Focal Segmental; Hypercholesterolemia; Kidney Glomerulus; Lovastatin; Nephrotic Syndrome; Rats; Rats, Inbred Strains; Uremia	1990
The politics of cholesterol lowering drugs. The New Zealand medical journal, 1990, Jan-24, Volume: 103, Issue:882 Topics: Anticholesteremic Agents; Humans; Hypercholesterolemia; Lovastatin; Middle Aged; New Zealand; Politics; Simvastatin	1990
Simvastatin therapy for hypercholesterolaemia in patients with coronary heart disease. The New Zealand medical journal, 1990, Feb-14, Volume: 103, Issue:883 Topics: Anticholesteremic Agents; Cholesterol; Cholesterol, LDL; Coronary Disease; Drug Tolerance; Female; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Placebos; Simvastatin; Single-Blind Method; Triglycerides	1990
Decreased mitogenic activity in hypercholesterolaemic plasma. Journal of internal medicine, 1990, Volume: 227, Issue:5 Topics: Adult; Aged; Animals; Anticholesteremic Agents; Apolipoproteins B; Cells, Cultured; Cholesterol; DNA; Female; Humans; Hypercholesterolemia; Lipoproteins; Lovastatin; Male; Middle Aged; Mitogens; Muscle, Smooth, Vascular; Rats; Simvastatin	1990
Myopathy and rhabdomyolysis associated with lovastatin-gemfibrozil combination therapy. JAMA, 1990, Jul-04, Volume: 264, Issue:1 Topics: Acute Kidney Injury; Adult; Aged; Creatine Kinase; Drug Interactions; Drug Therapy, Combination; Female; Gemfibrozil; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Muscular Diseases; Rhabdomyolysis	1990
Effects of lovastatin therapy on LDL receptor activity in circulating monocytes and on structure and composition of plasma lipoproteins. Atherosclerosis, 1990, Volume: 82, Issue:1-2 Topics: Apolipoproteins; Centrifugation, Zonal; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lipids; Lipoproteins; Lovastatin; Monocytes; Receptors, LDL	1990
Long-term maintenance of therapeutic response to lovastatin in patients with familial and non-familial hypercholesterolemia: a 3-year follow-up. Atherosclerosis, 1990, Volume: 82, Issue:1-2 Topics: Adult; Aged; Cholesterol, LDL; Colestipol; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lipids; Lipoproteins; Lovastatin; Male; Middle Aged; Polyamines; Probucol; Triglycerides	1990
[Maximal therapy of hypercholesterolemia in coronary heart disease]. Therapeutische Umschau. Revue therapeutique, 1990, Volume: 47, Issue:6 Topics: Adult; Anticholesteremic Agents; Blood Component Removal; Cholesterol, LDL; Combined Modality Therapy; Coronary Disease; Enzyme Inhibitors; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Plasma Exchange; Simvastatin	1990
Lack of effect of lovastatin therapy on the parameters of whole-body cholesterol metabolism. The Journal of clinical investigation, 1990, Volume: 86, Issue:3 Topics: Adult; Aged; Cholesterol; Colestipol; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Metabolic Clearance Rate; Middle Aged; Niacin	1990
Persistent abnormalities in lipoprotein composition and cholesteryl ester transfer following lovastatin treatment. Journal of lipid research, 1990, Volume: 31, Issue:7 Topics: Adult; Aged; Carrier Proteins; Cholesterol Ester Transfer Proteins; Cholesterol Esters; Female; Glycoproteins; Humans; Hypercholesterolemia; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Lovastatin; Male; Middle Aged	1990
Ocular side effects of the lipid-lowering drug simvastatin? A one year follow-up. Lens and eye toxicity research, 1989, Volume: 6, Issue:1-2 Topics: Cataract; Cholesterol; Cholesterol, LDL; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lovastatin; Male; Middle Aged; Simvastatin	1989
Lovastatin reduces postprandial lipoprotein levels in hypercholesterolaemic patients with mild hypertriglyceridaemia. European journal of clinical investigation, 1989, Volume: 19, Issue:5 Topics: Adult; Aged; Cholesterol, LDL; Cholesterol, VLDL; Cholestyramine Resin; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Hypertriglyceridemia; Lipoproteins; Lovastatin; Male; Middle Aged; Triglycerides	1989
Suppression of lymphoid cell function in vitro by inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase by lovastatin. International journal of immunopharmacology, 1989, Volume: 11, Issue:8 Topics: Cytotoxicity, Immunologic; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; In Vitro Techniques; Interferon-gamma; Interleukin-2; Lovastatin; Lymphocyte Activation; Lymphocytes; Mevalonic Acid; Mitogens	1989
HMG CoA reductase inhibitors lower LDL cholesterol without reducing Lp(a) levels. Circulation, 1989, Volume: 80, Issue:5 Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol, LDL; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipoprotein(a); Lipoproteins; Lovastatin; Male; Middle Aged; Simvastatin	1989
Effects of inhibition of cholesterol synthesis by simvastatin on the production of adrenocortical steroid hormones and ACTH. Clinical endocrinology, 1989, Volume: 31, Issue:6 Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Cholesterol; Female; Humans; Hydrocortisone; Hypercholesterolemia; Hypothalamo-Hypophyseal System; Insulin; Lipoproteins, HDL; Lipoproteins, LDL; Lovastatin; Male; Middle Aged; Pituitary-Adrenal System; Placebos; Simvastatin	1989
Lovastatin and elevated creatine kinase: results of rechallenge. Lancet (London, England), 1989, Apr-01, Volume: 1, Issue:8640 Topics: Aged; Creatine Kinase; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged	1989
Raised serum lipoprotein during treatment with lovastatin. Lancet (London, England), 1989, Apr-22, Volume: 1, Issue:8643 Topics: Humans; Hypercholesterolemia; Lipoprotein(a); Lipoproteins; Lovastatin	1989
Lovastatin, isoprenes, and myopathy. Lancet (London, England), 1989, Nov-04, Volume: 2, Issue:8671 Topics: Creatine Kinase; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Muscular Diseases; Ubiquinone	1989
Plasma mevalonate response in lovastatin-related myopathy. Lancet (London, England), 1989, Nov-04, Volume: 2, Issue:8671 Topics: Aged; Creatine Kinase; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Mevalonic Acid; Middle Aged; Muscular Diseases	1989
Controlling cholesterol with drugs. The American journal of nursing, 1989, Volume: 89, Issue:12 Topics: Anticholesteremic Agents; Cholestyramine Resin; Drug Therapy, Combination; Humans; Hypercholesterolemia; Lovastatin; Niacin	1989
Lovastatin therapy for hypercholesterolemia in cardiac transplant recipients. The American journal of cardiology, 1989, Sep-15, Volume: 64, Issue:10 Topics: Adult; Cholesterol; Cholesterol, LDL; Female; Follow-Up Studies; Heart Transplantation; Humans; Hypercholesterolemia; Immunosuppressive Agents; Lovastatin; Male; Middle Aged; Postoperative Complications; Time Factors	1989
Effect of simvastatin on plasma lipids, apolipoproteins and lipoprotein particles in patients with primary hypercholesterolaemia. European journal of clinical pharmacology, 1989, Volume: 37, Issue:6 Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Apolipoproteins; Cholesterol; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Immunoenzyme Techniques; Lipoproteins; Lovastatin; Male; Middle Aged; Phospholipids; Simvastatin; Triglycerides	1989
Preventive effect of MK-733 (simvastatin), an inhibitor of HMG-CoA reductase, on hypercholesterolemia and atherosclerosis induced by cholesterol feeding in rabbits. Japanese journal of pharmacology, 1989, Volume: 49, Issue:1 Topics: Animals; Aorta; Arteriosclerosis; Cholesterol; Cholesterol, Dietary; Hypercholesterolemia; Lipids; Liver; Lovastatin; Male; Myocardium; Rabbits; Simvastatin	1989
Simvastatin: a one-a-day treatment for hypercholesterolemia. Symposium. June 10 to 12, 1988, Pebble Beach, California. The American journal of medicine, 1989, Oct-16, Volume: 87, Issue:4A Topics: Animals; Anticholesteremic Agents; Humans; Hypercholesterolemia; Lovastatin; Simvastatin	1989
Simvastatin: the clinical profile. The American journal of medicine, 1989, Oct-16, Volume: 87, Issue:4A Topics: Aged; Creatine Kinase; Drug Therapy, Combination; Eye; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipoproteinemia Type II; Liver; Lovastatin; Male; Middle Aged; Simvastatin; Transaminases	1989
[Lowering of the plasma lipid concentration with lovastatin. A clinical study in patients with primary hypercholesterolemia]. Deutsche medizinische Wochenschrift (1946), 1989, Nov-10, Volume: 114, Issue:45 Topics: Adult; Aged; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Female; Humans; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Molecular Structure; Triglycerides	1989
Cardiovascular effects of acute hypercholesterolemia in rabbits. Reversal with lovastatin treatment. The Journal of clinical investigation, 1989, Volume: 83, Issue:2 Topics: Animals; Cardiovascular System; Cholesterol, Dietary; Coronary Disease; Creatine Kinase; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Isoenzymes; Lovastatin; Male; Myocardium; Rabbits	1989
[Efficacy and safety of simvastatin, a new cholesterol-lowering drug]. Nederlands tijdschrift voor geneeskunde, 1989, Feb-18, Volume: 133, Issue:7 Topics: Anticholesteremic Agents; Cholesterol; Cholestyramine Resin; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin	1989
[Type IIa dyslipoproteinemia. Effects of simvastatin and bezafibrate on atherogenic and non-atherogenic lipoprotein particles]. Presse medicale (Paris, France : 1983), 1988, Dec-17, Volume: 17, Issue:45 Topics: Bezafibrate; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lipoproteins; Lovastatin; Simvastatin	1988
HMG-CoA reductase inhibitors for hypercholesterolemia. The New England journal of medicine, 1988, Nov-03, Volume: 319, Issue:18 Topics: Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Middle Aged	1988
Low plasma lipid levels and increased cholesterol synthesis after partial ileal bypass plus lovastatin in hypercholesterolemic rabbits. Surgery, 1988, Volume: 104, Issue:4 Topics: Animals; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Combined Modality Therapy; Diet; Hypercholesterolemia; Ileum; Intestinal Mucosa; Lipids; Lovastatin; Male; Rabbits	1988
Unnecessary alarm about lovastatin and cataracts. Journal of cataract and refractive surgery, 1988, Volume: 14, Issue:5 Topics: Cataract; Humans; Hypercholesterolemia; Lovastatin	1988
Current and new therapy for hypercholesterolemia. The Journal of the American Osteopathic Association, 1988, Volume: 88, Issue:7 Topics: Anticholesteremic Agents; Colestipol; Gemfibrozil; Humans; Hypercholesterolemia; Lovastatin; Niacin; Probucol	1988
Rhabdomyolysis and renal injury with lovastatin use. Report of two cases in cardiac transplant recipients. JAMA, 1988, Jul-08, Volume: 260, Issue:2 Topics: Acute Kidney Injury; Adult; Creatine Kinase; Heart Transplantation; Humans; Hypercholesterolemia; Legionellosis; Lovastatin; Male; Middle Aged; Rhabdomyolysis	1988
Hyperlipidemia following heart transplantation: natural history and intervention with mevinolin (lovastatin). Transplantation proceedings, 1987, Volume: 19, Issue:4 Suppl 5 Topics: Adult; Anticholesteremic Agents; Cholesterol; Female; Heart Transplantation; Humans; Hypercholesterolemia; Hyperlipidemias; Lovastatin; Male; Middle Aged; Naphthalenes; Postoperative Complications; Triglycerides	1987
Lovastatin to lower cholesterol levels. Nursing, 1988, Volume: 18, Issue:2 Topics: Humans; Hypercholesterolemia; Lovastatin	1988
Ocular examination before initiation of lovastatin (Mevacor) therapy. American journal of ophthalmology, 1988, Jan-15, Volume: 105, Issue:1 Topics: Cataract; Humans; Hypercholesterolemia; Lovastatin	1988
Lovastatin alone and in combination for treatment of primary hypercholesterolemia. Progress in clinical and biological research, 1988, Volume: 255 Topics: Adult; Aged; Anion Exchange Resins; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lovastatin; Male; Middle Aged; Niacin; Patient Compliance	1988
Drug management of hypercholesterolemia. American family physician, 1988, Volume: 37, Issue:2 Topics: Humans; Hypercholesterolemia; Lovastatin	1988
Effects of simvastatin on plasma lipid, lipoprotein and apolipoprotein concentrations in hypercholesterolaemia. European heart journal, 1988, Volume: 9, Issue:5 Topics: Adult; Aged; Apolipoproteins; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Female; Humans; Hypercholesterolemia; Lipoproteins; Lovastatin; Male; Middle Aged; Simvastatin	1988
Intestinal HMG-CoA reductase activity is low in hypercholesterolemic patients and is further decreased with lovastatin therapy. Journal of lipid research, 1988, Volume: 29, Issue:7 Topics: Bile; Cholestyramine Resin; Female; Humans; Hydroxymethylglutaryl CoA Reductases; Hypercholesterolemia; Intestinal Mucosa; Jejunum; Lovastatin; Male; Middle Aged	1988
Current pharmacologic treatment of elevated serum cholesterol. Circulation, 1987, Volume: 76, Issue:3 Topics: Adult; Anticholesteremic Agents; Cholesterol; Cholesterol, LDL; Cholestyramine Resin; Clofibrate; Colestipol; Drug Tolerance; Female; Gemfibrozil; Humans; Hypercholesterolemia; Hyperlipidemias; Hyperlipoproteinemia Type II; Lovastatin; Male; Middle Aged; Naphthalenes; Neomycin; Niacin; Pentanoic Acids; Probucol; Simvastatin; Triglycerides	1987
Lipoprotein fractions and receptors: a role for probucol? The American journal of cardiology, 1986, Jun-27, Volume: 57, Issue:16 Topics: Anticholesteremic Agents; Biological Transport; Cholesterol; Cholesterol, Dietary; Cholesterol, HDL; Cholesterol, LDL; Colestipol; Humans; Hydroxymethylglutaryl CoA Reductases; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lipoproteins; Lipoproteins, HDL; Lipoproteins, IDL; Lipoproteins, VLDL; Lovastatin; Naphthalenes; Phenols; Probucol; Receptors, LDL	1986
Comparison of six pharmacologic regimens for hypercholesterolemia. The American journal of cardiology, 1987, Apr-01, Volume: 59, Issue:8 Topics: Adult; Aged; Cholestyramine Resin; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lovastatin; Male; Middle Aged; Naphthalenes; Neomycin; Niacin; Retrospective Studies	1987
[Treatment with mevinolin in a patient with pseudo-homozygous hypercholesterolemia]. Medicina clinica, 1987, Feb-07, Volume: 88, Issue:5 Topics: Anticholesteremic Agents; Diagnosis, Differential; Female; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lovastatin; Naphthalenes	1987
Long term administration of lovastatin in the treatment of hypercholesterolaemia. European heart journal, 1987, Volume: 8 Suppl E Topics: Adult; Cholesterol; Drug Administration Schedule; Female; Humans; Hypercholesterolemia; Hyperlipidemia, Familial Combined; Hyperlipoproteinemia Type II; Lipoproteins; Lovastatin; Male; Middle Aged	1987
Lovastatin: cholesterol-lowering agent. American family physician, 1987, Volume: 36, Issue:6 Topics: Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Humans; Hypercholesterolemia; Lovastatin; Probucol	1987