Page last updated: 2024-08-23

lovastatin and Cataract

lovastatin has been researched along with Cataract in 31 studies

Research

Studies (31)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (29.03)	18.7374
1990's	19 (61.29)	18.2507
2000's	2 (6.45)	29.6817
2010's	1 (3.23)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cheng, Q; Gerald Robison, W; Samuel Zigler, J	1
MacDonald, JS	1
Chylack, LT; Friend, J; Mantell, G; Rosner, B; Wolfe, JK	1
Bettelheim, F; Lin, LR; Rao, PV; Reddy, VN; Robison, WG; Zigler, JS	1
Bariciak, MD; Nichols, BD	1
Cheng, QF; Rao, PV; Zigler, JS	1
Behrens-Baumann, W; Fieseler, HG; Seidel, D; Thiery, J; Wieland, E	1
Lehto, S; Leino, M; Pyörälä, K; Rantala, A	1
Behrens-Baumann, W; Thiery, J	1
Schneider, T; Ulbig, M	1
Hockwin, O; Schmidt, J; Schmitt, C	2
Bocanegra, TS; Boccuzzi, SJ; Keegan, ME; Shapiro, DR; Walker, JF	1
Chremos, AN; Gould, AL; Hurley, DP; Keates, EU; Laties, AM; Lippa, EA; Shear, CL; Stephenson, WP; Taylor, HR; Tupy-Visich, MA	1
Langer, J	1
Lundh, BL; Nilsson, SE	1
Burke, MT; Mantell, G; Staggers, J	1
Alberts, AW; Bokelman, DL; Chen, J; Gerson, RJ; Greenspan, MD; MacDonald, JS; Rubin, LF; Yudkovitz, JB	1
Chremos, AN; Gould, AL; Hurley, DP; Keates, EU; Laties, AM; Lippa, EA; Shear, CL; Taylor, HR	1
Bach, LA; Cooper, ME; Jerums, G; O'Brien, RC	1
Kreisberg, R; Mantell, G; Miller, V; Shapiro, DR; Stein, E; Washington, L	1
Behrens-Baumann, W; Creutzfeldt, C; Morawietz, A; Seidel, D; Thiery, J	1
Alberts, AW; Bokelman, DL; Gerson, RJ; Kornbrust, DJ; MacDonald, JS; Majka, JA; Stubbs, RJ	1
Alberts, AW; Berry, PH; Bokelman, DL; Gerson, RJ; Kloss, MW; Kornbrust, DJ; MacDonald, JS; Prahalada, S	1
Schechter, RJ	1
Goldberg, I; Hunninghake, DB; Miller, VT; Schonfeld, G; Stein, EA; Tobert, JA	1
Fraunfelder, FT	1
Cenedella, RJ	1
Bacon, SR; Bolognese, JA; Frost, PH; Havel, RJ; Hunninghake, DB; Illingworth, DR; Lamkin, GE; Lees, RS; Stein, EA; Tobert, JA	1

Reviews

4 review(s) available for lovastatin and Cataract

Article	Year
Cataracts in systemic diseases and syndromes. Current opinion in ophthalmology, 1995, Volume: 6, Issue:1 Topics: Amiodarone; Cataract; Cataract Extraction; Diabetes Complications; Diabetic Retinopathy; Female; Humans; Lens, Crystalline; Lovastatin; Male; Neurofibromatosis 2; Propranolol; Syndrome	1995
Extended clinical safety profile of lovastatin. The American journal of cardiology, 1990, Sep-18, Volume: 66, Issue:8 Topics: Cataract; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Drug Evaluation; Humans; Lovastatin; Multicenter Studies as Topic; Muscular Diseases	1990
Animal safety and toxicology of simvastatin and related hydroxy-methylglutaryl-coenzyme A reductase inhibitors. The American journal of medicine, 1989, Oct-16, Volume: 87, Issue:4A Topics: Animals; Cataract; Dogs; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Lovastatin; Male; Necrosis; Rabbits; Rats; Simvastatin; Species Specificity; Stomach; Testis	1989
Preclinical evaluation of lovastatin. The American journal of cardiology, 1988, Nov-11, Volume: 62, Issue:15 Topics: Animals; Cataract; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Lovastatin; Neoplasms, Experimental; Risk Factors	1988

Trials

13 trial(s) available for lovastatin and Cataract

Article	Year
Lovastatin and the human lens; results of a two year study. The MSDRL Study Group. Optometry and vision science : official publication of the American Academy of Optometry, 1993, Volume: 70, Issue:11 Topics: Cataract; Contrast Sensitivity; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Image Processing, Computer-Assisted; Lens, Crystalline; Longitudinal Studies; Lovastatin; Male; Middle Aged; Photography; Visual Acuity	1993
Lens opacity in patients with hypercholesterolemia and ischaemic heart disease. Electronic lens opacity measurements. Documenta ophthalmologica. Advances in ophthalmology, 1992, Volume: 80, Issue:4 Topics: Adult; Aged; Cataract; Double-Blind Method; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Myocardial Ischemia; Ophthalmology; Reproducibility of Results; Simvastatin	1992
Long-term safety and efficacy profile of simvastatin. The American journal of cardiology, 1991, Nov-01, Volume: 68, Issue:11 Topics: Aged; Anticholesteremic Agents; Cataract; Coronary Disease; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Liver; Lovastatin; Male; Middle Aged; Muscles; Simvastatin	1991
Expanded clinical evaluation of lovastatin (EXCEL) study results. II. Assessment of the human lens after 48 weeks of treatment with lovastatin. The American journal of cardiology, 1991, Mar-01, Volume: 67, Issue:6 Topics: Adolescent; Adult; Aged; Cataract; Double-Blind Method; Female; Humans; Hypercholesterolemia; Lens, Crystalline; Lovastatin; Male; Middle Aged; Visual Acuity	1991
Lens changes in matched normals and hyperlipidemic patients treated with simvastatin for 2 years. Acta ophthalmologica, 1990, Volume: 68, Issue:6 Topics: Adult; Aged; Cataract; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Lens, Crystalline; Lovastatin; Male; Middle Aged; Simvastatin; Vacuoles	1990
Extended clinical safety profile of lovastatin. The American journal of cardiology, 1990, Sep-18, Volume: 66, Issue:8 Topics: Cataract; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Drug Evaluation; Humans; Lovastatin; Multicenter Studies as Topic; Muscular Diseases	1990
The human lens after 48 weeks of treatment with lovastatin. The New England journal of medicine, 1990, Sep-06, Volume: 323, Issue:10 Topics: Adult; Aged; Cataract; Female; Humans; Lens, Crystalline; Lovastatin; Male; Middle Aged; Time Factors; Visual Acuity	1990
The use of simvastatin, an HMG CoA reductase inhibitor, in older patients with hypercholesterolemia and atherosclerosis. Journal of the American Geriatrics Society, 1990, Volume: 38, Issue:1 Topics: Aged; Anticholesteremic Agents; Arteriosclerosis; Cataract; Cholesterol, HDL; Cholesterol, LDL; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Lovastatin; Male; Randomized Controlled Trials as Topic; Simvastatin	1990
Effects of simvastatin and cholestyramine in familial and nonfamilial hypercholesterolemia. Multicenter Group I. Archives of internal medicine, 1990, Volume: 150, Issue:2 Topics: Adult; Alanine Transaminase; Anticholesteremic Agents; Cataract; Cholesterol; Cholestyramine Resin; Creatine Kinase; Female; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lipoproteins; Lovastatin; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Simvastatin; Triglycerides	1990
Lovastatin for hypercholesterolemia. The Medical letter on drugs and therapeutics, 1987, Nov-06, Volume: 29, Issue:752 Topics: Cataract; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Humans; Hypercholesterolemia; Lovastatin; Myositis; Random Allocation	1987
Lovastatin: follow-up ophthalmologic data. JAMA, 1988, Jan-15, Volume: 259, Issue:3 Topics: Aged; Cataract; Double-Blind Method; Female; Follow-Up Studies; Humans; Lovastatin; Male; Middle Aged	1988
Inhibitors of cholesterol synthesis and cataracts. JAMA, 1987, Mar-27, Volume: 257, Issue:12 Topics: Age Factors; Animals; Anticholesteremic Agents; Cataract; Cholesterol; Humans; Infant; Lovastatin; Middle Aged; Naphthalenes; Rats	1987
Lovastatin (mevinolin) in the treatment of heterozygous familial hypercholesterolemia. A multicenter study. Annals of internal medicine, 1987, Volume: 107, Issue:5 Topics: Adult; Alanine Transaminase; Apolipoproteins B; Cataract; Cholesterol; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; Female; Heterozygote; Humans; Hyperlipoproteinemia Type II; Lovastatin; Male; Random Allocation	1987

Other Studies

15 other study(ies) available for lovastatin and Cataract

Article	Year
Is your cholesterol drug putting you at risk for vision loss? Harvard health letter, 2013, Volume: 39, Issue:2 Topics: Anticholesteremic Agents; Cataract; Health Status; Humans; Lovastatin; Risk Factors; Risk Reduction Behavior	2013
Geranylgeranyl pyrophosphate counteracts the cataractogenic effect of lovastatin on cultured rat lenses. Experimental eye research, 2002, Volume: 75, Issue:5 Topics: Animals; Anticholesteremic Agents; Apoptosis; Cataract; Cells, Cultured; Epithelium; In Situ Nick-End Labeling; Lens Capsule, Crystalline; Lovastatin; Polyisoprenyl Phosphates; Protein Prenylation; Rats; Sesquiterpenes	2002
Perspective on cataractogenic potential of HMG-CoA reductase inhibitors. Experimental eye research, 1995, Volume: 60, Issue:1 Topics: Animals; Cataract; Dogs; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Pravastatin; Rabbits; Rats; Simvastatin	1995
Role of small GTP-binding proteins in lovastatin-induced cataracts. Investigative ophthalmology & visual science, 1997, Volume: 38, Issue:11 Topics: Animals; Cataract; Cell Differentiation; Cell Division; Cells, Cultured; Epithelium; GTP-Binding Proteins; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infant; Lens, Crystalline; Lovastatin; Macaca mulatta; Mevalonic Acid; Microscopy, Electron, Scanning; Organ Culture Techniques; Protein Prenylation; Rabbits; Rats; Rats, Sprague-Dawley	1997
Effect of perillic acid, a putative isoprenylation inhibitor, on the cultured rat lens. Experimental eye research, 2001, Volume: 73, Issue:2 Topics: Animals; Antineoplastic Agents, Phytogenic; Cataract; Cyclohexenes; Diterpenes; Dose-Response Relationship, Drug; Farnesol; Female; GTP Phosphohydrolases; Lens, Crystalline; Lovastatin; Male; Monoterpenes; Organ Culture Techniques; Protein Prenylation; Rats; Rats, Sprague-Dawley; Terpenes	2001
3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor simvastatin and the human lens. Clinical results of a 3-year follow-up. Arzneimittel-Forschung, 1992, Volume: 42, Issue:8 Topics: Adult; Aged; Cataract; Cholesterol; Cholesterol, HDL; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lens, Crystalline; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides	1992
Cataracts by lipid lowering drugs? Three different HMG-CoA reductase inhibitors studied in hypercholesterolemic rabbits. Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1992, Volume: 192, Issue:1 Topics: Animals; Anticholesteremic Agents; Cataract; Cholesterol; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lovastatin; Pravastatin; Rabbits; Simvastatin	1992
[Absence of cataractogenic effect of lovastatin (Mevinacor) so far]. Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1991, Volume: 88, Issue:5 Topics: Adult; Aged; Cataract; Female; Follow-Up Studies; Humans; Hyperlipoproteinemia Type II; Lens, Crystalline; Lovastatin; Male; Middle Aged; Prospective Studies	1991
[The HMG-CoA reductase inhibitors simvastatin and pravastatin. No indication for side effects in use on humans]. Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1991, Volume: 88, Issue:6 Topics: Adult; Cataract; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemias; Lovastatin; Middle Aged; Pravastatin; Refraction, Ocular; Risk Factors; Simvastatin; Visual Acuity	1991
[Drug against high cholesterol can affect vision]. Sygeplejersken, 1991, Jan-23, Volume: 91, Issue:4 Topics: Cataract; Humans; Lovastatin	1991
No lens changes caused by simvastatin results from a prospective drug safety study. Lens and eye toxicity research, 1990, Volume: 7, Issue:3-4 Topics: Adult; Aged; Cataract; Drug Evaluation; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intraocular Pressure; Lens, Crystalline; Lovastatin; Male; Middle Aged; Photography; Prospective Studies; Simvastatin; Visual Acuity	1990
On the etiology of subcapsular lenticular opacities produced in dogs receiving HMG-CoA reductase inhibitors. Experimental eye research, 1990, Volume: 50, Issue:1 Topics: Animals; Anticholesteremic Agents; Biphenyl Compounds; Cataract; Cholesterol; Dogs; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Pyrans; Pyrones; Simvastatin	1990
Ocular side effects of the lipid-lowering drug simvastatin? A one year follow-up. Lens and eye toxicity research, 1989, Volume: 6, Issue:1-2 Topics: Cataract; Cholesterol; Cholesterol, LDL; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lovastatin; Male; Middle Aged; Simvastatin	1989
Unnecessary alarm about lovastatin and cataracts. Journal of cataract and refractive surgery, 1988, Volume: 14, Issue:5 Topics: Cataract; Humans; Hypercholesterolemia; Lovastatin	1988
Ocular examination before initiation of lovastatin (Mevacor) therapy. American journal of ophthalmology, 1988, Jan-15, Volume: 105, Issue:1 Topics: Cataract; Humans; Hypercholesterolemia; Lovastatin	1988