lovastatin has been researched along with Carcinoma, Epidermoid in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 6 (40.00) | 29.6817 |
| 2010's | 8 (53.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Corsten, M; Dimitroulakos, J; Gorn-Hondermann, I; Johnson-Obeseki, S; Ma, L; Niknejad, N; Zahr, S | 1 |
| Wang, J; Wu, Q; Wu, X; Zhang, LH; Zhao, YX | 1 |
| Desai, M; Hedlin, H; Kapphahn, K; Manson, JA; Martin, L; Simon, M; Stefanick, ML; Strickler, H; Tang, JY; Wactawski-Wende, J; Wang, A | 1 |
| Gaggioli, C; Hooper, S; Sahai, E | 1 |
| Bradbury, PA; Dimitroulakos, J; Ding, K; Goss, G; Le Francois, BG; Zhao, TT | 1 |
| Chang, JZ; Cheng, SJ; Deng, YT; Kuo, MY; Yeh, CC | 1 |
| Dayekh, K; Dimitroulakos, J; Gorn-Hondermann, I; Ma, L; Niknejad, N | 1 |
| Shi, J; Xu, Z; Yao, F; Zhao, H; Zhong, C; Zhu, J | 1 |
| Dimitroulakos, J; Goss, G; Lorimer, IA; Mantha, AJ; McFee, KE; Niknejad, N | 1 |
| Chen, E; Chin, S; Dimitroulakos, J; Irish, J; Kamel-Reid, S; Knox, JJ; LaFramboise, S; Moore, MJ; Oza, AM; Siu, LL | 1 |
| Dimitroulakos, J; Goss, G; Hanson, JE; Lagarde, AE; Lorimer, IA; Mantha, AJ | 1 |
| Dellavalle, RP; Gendall, J; Kelly, D; Miller, L; Norris, DA; Ribble, D; Shellman, YG; Vanbuskirk, K | 1 |
| Dimitroulakos, J; Morley, M; Niknejad, N | 1 |
| Baumann, M; Dörfler, A; Gabryś, D; Hessel, F; Krause, M; Oertel, R; Yaromina, A | 1 |
| Raymond, Y; Sasseville, AM | 1 |
1 trial(s) available for lovastatin and Carcinoma, Epidermoid
| Article | Year |
|---|---|
A Phase I trial of prolonged administration of lovastatin in patients with recurrent or metastatic squamous cell carcinoma of the head and neck or of the cervix.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Middle Aged; Neoplasm Recurrence, Local; Treatment Outcome; Uterine Cervical Neoplasms | 2005 |
14 other study(ies) available for lovastatin and Carcinoma, Epidermoid
| Article | Year |
|---|---|
Lovastatin-induced apoptosis is mediated by activating transcription factor 3 and enhanced in combination with salubrinal.
Topics: Activating Transcription Factor 3; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Breast Neoplasms; Carcinoma, Squamous Cell; Cell Membrane Permeability; Cell Proliferation; Cinnamates; Drug Resistance, Neoplasm; Drug Synergism; Embryo, Mammalian; Eukaryotic Initiation Factor-2; Female; Fibroblasts; Flow Cytometry; Head and Neck Neoplasms; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoenzyme Techniques; Lovastatin; Male; Membrane Potential, Mitochondrial; Mice; Phosphorylation; Prostatic Neoplasms; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Thiourea; Tumor Cells, Cultured | 2014 |
The role of RhoA in vulvar squamous cell carcinoma: a carcinogenesis, progression, and target therapy marker.
Topics: Adult; Aged; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Line, Tumor; Disease Progression; Female; Humans; Immunohistochemistry; Lovastatin; Middle Aged; Molecular Targeted Therapy; rhoA GTP-Binding Protein; Vulvar Neoplasms | 2016 |
Relation of statin use with non-melanoma skin cancer: prospective results from the Women's Health Initiative.
Topics: Age Factors; Aged; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cohort Studies; Environmental Exposure; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Indoles; Logistic Models; Longitudinal Studies; Lovastatin; Middle Aged; Odds Ratio; Overweight; Prospective Studies; Pyridines; Risk Factors; Simvastatin; Skin Neoplasms; Smoking; Sunlight; Vitamin D; Vitamins; White People | 2016 |
A chemical biology screen reveals a role for Rab21-mediated control of actomyosin contractility in fibroblast-driven cancer invasion.
Topics: Actomyosin; Carcinoma, Squamous Cell; Extracellular Matrix; Fibroblasts; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Integrin alpha5; Lovastatin; Muscle Contraction; Neoplasm Invasiveness; rab GTP-Binding Proteins; Simvastatin | 2010 |
Lovastatin inhibits EGFR dimerization and AKT activation in squamous cell carcinoma cells: potential regulation by targeting rho proteins.
Topics: Amides; Animals; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cell Line, Tumor; Cytoskeleton; Dimerization; Drug Interactions; Enzyme Activation; ErbB Receptors; Head and Neck Neoplasms; Humans; Lovastatin; Lung Neoplasms; Mice; NIH 3T3 Cells; Polyisoprenyl Phosphates; Proto-Oncogene Proteins c-akt; Pyridines; rho-Associated Kinases; Signal Transduction | 2010 |
Arecoline stimulated Cyr61 production in human gingival epithelial cells: inhibition by lovastatin.
Topics: Areca; Arecoline; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Cysteine-Rich Protein 61; Epithelial Cells; Gene Expression Regulation, Neoplastic; Gingiva; Humans; Lovastatin; Male; Mouth Neoplasms; Plant Extracts; Reverse Transcriptase Polymerase Chain Reaction; Up-Regulation | 2011 |
Lovastatin induces multiple stress pathways including LKB1/AMPK activation that regulate its cytotoxic effects in squamous cell carcinoma cells.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Cell Line; Cell Line, Tumor; Drug Synergism; Fibroblasts; Gefitinib; Gene Deletion; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Lovastatin; Metformin; Mice; Protein Serine-Threonine Kinases; Quinazolines; Signal Transduction | 2012 |
Mevalonate pathway is a therapeutic target in esophageal squamous cell carcinoma.
Topics: Animals; Apoptosis; Carcinoma, Squamous Cell; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Extracellular Signal-Regulated MAP Kinases; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; MAP Kinase Signaling System; Mevalonic Acid; Mice; Mice, Nude; Neoplasm Transplantation; Poly(ADP-ribose) Polymerases; Proliferating Cell Nuclear Antigen; Transplantation, Heterologous | 2013 |
Epidermal growth factor receptor-targeted therapy potentiates lovastatin-induced apoptosis in head and neck squamous cell carcinoma cells.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cycloheximide; Dactinomycin; Drug Delivery Systems; ErbB Receptors; Head and Neck Neoplasms; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Protein-Tyrosine Kinases | 2003 |
Targeting the mevalonate pathway inhibits the function of the epidermal growth factor receptor.
Topics: Adenosine Triphosphate; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Binding Sites; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Colonic Neoplasms; Drug Synergism; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Gefitinib; Humans; Lovastatin; Lung Neoplasms; Mevalonic Acid; Mitogen-Activated Protein Kinases; Mutation; Phosphorylation; Quinazolines; Signal Transduction; Tumor Cells, Cultured | 2005 |
Lovastatin-induced apoptosis in human melanoma cell lines.
Topics: Animals; Anticholesteremic Agents; Apoptosis; Carcinoma, Squamous Cell; Caspase 3; Caspases; Cell Proliferation; Dimethylallyltranstransferase; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Melanoma; Mice; Polyisoprenyl Phosphates; Pravastatin; Sesquiterpenes | 2005 |
Activation of the integrated stress response regulates lovastatin-induced apoptosis.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Drug Screening Assays, Antitumor; Eukaryotic Initiation Factor-2; Fibroblasts; Head and Neck Neoplasms; Humans; Lovastatin; Mevalonic Acid; Mice; Models, Biological; Phosphorylation; Prodrugs | 2007 |
Effects of lovastatin alone or combined with irradiation on tumor cells in vitro and in vivo.
Topics: Animals; Apoptosis; Brain Neoplasms; Carcinoma, Squamous Cell; Cell Cycle; Cell Division; Cell Line, Tumor; Combined Modality Therapy; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Glioma; Humans; Hypopharyngeal Neoplasms; In Vitro Techniques; Lovastatin; Mice; Mice, Nude; Neoplasm Transplantation; Radiation Dosage; Tumor Cells, Cultured; Tumor Stem Cell Assay | 2008 |
Lamin A precursor is localized to intranuclear foci.
Topics: Amino Acid Sequence; Carcinoma, Squamous Cell; Cell Line; Cell Nucleus; Cysteine; DNA, Complementary; Fluorescent Antibody Technique; Humans; Lamin Type A; Lamins; Lovastatin; Mevalonic Acid; Nuclear Proteins; Protein Precursors; Protein Prenylation; Protein Processing, Post-Translational; Recombinant Proteins; Tumor Cells, Cultured | 1995 |