lovastatin has been researched along with Cancer of the Thyroid in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 7 (50.00) | 29.6817 |
| 2010's | 6 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chin, LH; Hsu, SP; Liang, YC; Zhong, WB | 1 |
| Brossart, P; Fröhlich, E; Wahl, R | 1 |
| Chang, TC; Shui, HA; Wang, CY | 1 |
| Engel, E; Fröhlich, E; Wahl, R | 1 |
| Cho, S; Choi, HJ; Choi, JY; Chung, YS; Jee, HG; Lee, KE; Oh, SK; Ryou, HJ; Suh, YJ; Yoon, K; Youn, YK | 1 |
| Chang, TC; Ho, PY; Hsu, SP; Lee, WS; Liang, YC; Zhong, WB | 1 |
| Chang, TC; Chen, HM; Hsia, CW; Shui, HA; Wang, CY | 1 |
| Robbins, RJ | 1 |
| Chang, TC; Lai, SM; Tsai, YF; Wang, CY; Zhong, WB | 1 |
| Chang, TC; Lee, WS; Wang, CY; Zhong, WB | 1 |
| Chang, TC; Lee, WS; Liang, YC; Wang, CY; Zhong, WB | 1 |
| Bifulco, M; Ferraro, A; Fusco, A; Iacuzzo, I; Libertini, S; Portella, G; Vitale, M | 1 |
| Bifulco, M | 1 |
| Deluca, JG; Germershausen, JI; Gerson, RJ; Gordon, LR; Grossman, SJ; MacDonald, JS; Majka, JA; Smith, PF; Wang, RW | 1 |
2 review(s) available for lovastatin and Cancer of the Thyroid
| Article | Year |
|---|---|
Statins sentence thyroid cancer cells to death rho.
Topics: Carcinoma; Cell Death; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; rho GTP-Binding Proteins; Thyroid Neoplasms | 2003 |
Therapeutic potential of statins in thyroid proliferative disease.
Topics: Animals; Apoptosis; Cell Growth Processes; Cell Line, Tumor; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Thyroid Neoplasms | 2008 |
12 other study(ies) available for lovastatin and Cancer of the Thyroid
| Article | Year |
|---|---|
Combined treatment with troglitazone and lovastatin inhibited epidermal growth factor-induced migration through the downregulation of cysteine-rich protein 61 in human anaplastic thyroid cancer cells.
Topics: Cell Line, Tumor; Cell Movement; Chromans; Cyclic AMP Response Element-Binding Protein; Cysteine-Rich Protein 61; Down-Regulation; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Humans; Lovastatin; Signal Transduction; Thiazolidinediones; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Troglitazone | 2015 |
Induction of iodide uptake in transformed thyrocytes: a compound screening in cell lines.
Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Boronic Acids; Bortezomib; Carcinoma; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Iodides; Lovastatin; Neoplasm Metastasis; Oxides; Pyrazines; Sirolimus; Thymus Gland; Thyroid Neoplasms; Tretinoin | 2009 |
In vivo evidence of duality effects for lovastatin in a nude mouse cancer model.
Topics: Animals; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Lovastatin; Mice; Mice, Inbred BALB C; Mice, Nude; Receptors, Vascular Endothelial Growth Factor; Thyroid Neoplasms; Treatment Outcome; Tumor Burden; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2010 |
Decrease in dipeptidyl peptidase IV activity is linked to the efficacy of differentiating compounds in follicular thyroid carcinoma cell lines.
Topics: Adenocarcinoma, Follicular; Antineoplastic Agents; Cell Differentiation; Cell Line, Tumor; Dipeptidyl Peptidase 4; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Lovastatin; Thyroid Neoplasms; Vitamin A | 2011 |
Is there a treatment advantage when paclitaxel and lovastatin are combined to dose anaplastic thyroid carcinoma cell lines?
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Survival; Humans; Lovastatin; Paclitaxel; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms | 2011 |
Lovastatin inhibits proliferation of anaplastic thyroid cancer cells through up-regulation of p27 by interfering with the Rho/ROCK-mediated pathway.
Topics: Cell Cycle; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p27; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mevalonic Acid; Polyisoprenyl Phosphates; Protein Stability; Protein Transport; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction; Thyroid Neoplasms; Up-Regulation | 2011 |
Proteomics and bioinformatics analysis of lovastatin-induced differentiation in ARO cells.
Topics: Blotting, Western; Cloning, Molecular; Computational Biology; DNA Fragmentation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Membrane Proteins; Protein Folding; Proteomics; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thyroid Neoplasms | 2012 |
Lovastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, induces apoptosis and differentiation in human anaplastic thyroid carcinoma cells.
Topics: Apoptosis; Carcinoma; Cell Differentiation; Cell Survival; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Microscopy, Electron, Scanning; Protein Prenylation; Radioimmunoassay; Thyroglobulin; Thyroid Neoplasms; Tumor Cells, Cultured | 2003 |
Lovastatin induces apoptosis of anaplastic thyroid cancer cells via inhibition of protein geranylgeranylation and de novo protein synthesis.
Topics: Anticholesteremic Agents; Apoptosis; Caspases; Cell Membrane; Cell Survival; Cytochrome c Group; Cytosol; Diterpenes; Humans; Intracellular Signaling Peptides and Proteins; Lovastatin; Protein Prenylation; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; rho GTP-Binding Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; Thyroid Neoplasms; Tumor Cells, Cultured | 2003 |
Lovastatin suppresses invasiveness of anaplastic thyroid cancer cells by inhibiting Rho geranylgeranylation and RhoA/ROCK signaling.
Topics: Actins; Antineoplastic Agents; Collagen; Drug Combinations; Flow Cytometry; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Laminin; Lovastatin; Neoplasm Invasiveness; Proteoglycans; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; Signal Transduction; Thyroid Neoplasms; Tumor Cells, Cultured | 2005 |
Lovastatin enhances the replication of the oncolytic adenovirus dl1520 and its antineoplastic activity against anaplastic thyroid carcinoma cells.
Topics: Adenoviridae; Animals; Antineoplastic Agents; Carcinoma; Cells, Cultured; Combined Modality Therapy; Female; Humans; Lovastatin; Mice; Mice, Nude; Oncolytic Virotherapy; Oncolytic Viruses; Thyroid Neoplasms; Viral Vaccines; Virus Replication; Xenograft Model Antitumor Assays | 2007 |
Studies on the mechanism of simvastatin-induced thyroid hypertrophy and follicular cell adenoma in the rat.
Topics: Adenoma; Animals; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertrophy; Liver; Lovastatin; Microsomes, Liver; Organ Size; Phenobarbital; Rats; Rats, Inbred Strains; Simvastatin; Thyroid Gland; Thyroid Hormones; Thyroid Neoplasms; Thyroxine; Time Factors | 1991 |