lovastatin has been researched along with Brain Neoplasms in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, SY; Kiang, KMY; Leung, GK; Li, N; Wong, VK; Zhang, P; Zhu, Z | 1 |
| Afshordel, S; Clasohm, J; Eckert, GP; Kern, B; Kögel, D; König, H; Priester, M; Weissenberger, J | 1 |
| Barrett, GM; Cemeus, C; Dimitroulakos, J; Lorimer, IA; Zhao, TT | 1 |
| Becker Buscaglia, LE; Choudhury, S; Li, Y; Liu, M; Martin, RC; Park, AK; Park, WY; Takwi, AA; Young, KH; Zhang, J | 1 |
| Chan, CF; Cheng, AL; Chuang, SE; Lai, GM; Yang, YY; Yao, CJ | 1 |
| Baumann, M; Dörfler, A; Gabryś, D; Hessel, F; Krause, M; Oertel, R; Yaromina, A | 1 |
| Liu, L; Prasanna, P; Samid, D; Thibault, A | 1 |
| Jane, J; Larner, J; Laws, E; Myers, C; Packer, R; Shaffrey, M | 1 |
| Lin, SJ; Liu, HS; Wang, YS; Yang, BC | 1 |
| Dichgans, J; Groscurth, P; Kermer, M; Schmidt, F; Weller, M | 1 |
1 trial(s) available for lovastatin and Brain Neoplasms
| Article | Year |
|---|---|
A phase I-II trial of lovastatin for anaplastic astrocytoma and glioblastoma multiforme.
Topics: Adult; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Female; Glioblastoma; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Middle Aged; Radiation-Sensitizing Agents; Radiotherapy, Adjuvant | 1998 |
9 other study(ies) available for lovastatin and Brain Neoplasms
| Article | Year |
|---|---|
Lovastatin Enhances Cytotoxicity of Temozolomide via Impairing Autophagic Flux in Glioblastoma Cells.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Dyneins; Glioblastoma; Humans; Lovastatin; Lysosomal-Associated Membrane Protein 2; Proto-Oncogene Proteins c-akt; Signal Transduction; Temozolomide; TOR Serine-Threonine Kinases; Tumor Stem Cell Assay | 2019 |
Lovastatin and perillyl alcohol inhibit glioma cell invasion, migration, and proliferation--impact of Ras-/Rho-prenylation.
Topics: Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cholesterol; Glioma; Humans; Lovastatin; Monoterpenes; Neoplasm Invasiveness; Prenylation; rac1 GTP-Binding Protein; ras Proteins; Terpenes | 2015 |
Lovastatin enhances gefitinib activity in glioblastoma cells irrespective of EGFRvIII and PTEN status.
Topics: Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; ErbB Receptors; Flow Cytometry; Gefitinib; Glioblastoma; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; PTEN Phosphohydrolase; Quinazolines | 2008 |
A statin-regulated microRNA represses human c-Myc expression and function.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line; Cell Proliferation; Humans; Lovastatin; Male; Medulloblastoma; Mice; MicroRNAs; Proto-Oncogene Proteins c-myc; Survival Analysis | 2012 |
Dramatic synergistic anticancer effect of clinically achievable doses of lovastatin and troglitazone.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Survival; Chromans; Cyclin A; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p27; Dose-Response Relationship, Drug; Drug Synergism; E2F1 Transcription Factor; Glioblastoma; HeLa Cells; Humans; Lovastatin; Lung Neoplasms; Male; Pancreatic Neoplasms; Phosphorylation; Prostatic Neoplasms; Retinoblastoma Protein; Thiazolidinediones; Troglitazone; Tumor Cells, Cultured | 2006 |
Effects of lovastatin alone or combined with irradiation on tumor cells in vitro and in vivo.
Topics: Animals; Apoptosis; Brain Neoplasms; Carcinoma, Squamous Cell; Cell Cycle; Cell Division; Cell Line, Tumor; Combined Modality Therapy; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Glioma; Humans; Hypopharyngeal Neoplasms; In Vitro Techniques; Lovastatin; Mice; Mice, Nude; Neoplasm Transplantation; Radiation Dosage; Tumor Cells, Cultured; Tumor Stem Cell Assay | 2008 |
Lipid metabolism as a target for brain cancer therapy: synergistic activity of lovastatin and sodium phenylacetate against human glioma cells.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Division; Drug Synergism; Glioma; Humans; Lipid Metabolism; Lovastatin; Mevalonic Acid; Neoplasm Invasiveness; Phenylacetates; Tumor Cells, Cultured; Ubiquinone | 1996 |
Ras signaling is involved in the expression of Fas-L in glioma.
Topics: Antineoplastic Agents; Brain Neoplasms; Fas Ligand Protein; fas Receptor; Glioma; Humans; Lovastatin; Membrane Glycoproteins; Mutation; ras Proteins; Signal Transduction; Tumor Cells, Cultured | 2000 |
Lovastatin and phenylacetate induce apoptosis, but not differentiation, in human malignant glioma cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Astrocytes; Brain Neoplasms; Cell Cycle; Cell Differentiation; Cell Survival; Dose-Response Relationship, Drug; Drug Interactions; Fas Ligand Protein; Gene Expression Regulation, Neoplastic; Glial Fibrillary Acidic Protein; Glioma; Humans; Lovastatin; Membrane Glycoproteins; Microscopy, Electron; Mutation; Phenylacetates; Proto-Oncogene Proteins c-bcl-2; Rats; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2001 |