Page last updated: 2024-08-23

lovastatin and Atherogenesis

lovastatin has been researched along with Atherogenesis in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (27.59)29.6817
2010's18 (62.07)24.3611
2020's3 (10.34)2.80

Authors

AuthorsStudies
Jiu, Q; Liu, B; Tang, D; Wang, G; Wang, Y; Wijaya, A; Wu, W; Yan, M; Zhong, Y1
Shi, Y; Yan, M; Zhang, G; Zhang, L1
Cicero, AFG; Fogacci, F; Stoian, AP; Toth, PP1
He, J; Jiang, C; Liu, J; Yang, Y; Zhang, W; Zhao, Y1
Guo, C; Jing, Y; Li, P; Li, QZ; Liu, Z; Lu, JX; Niu, HF; Ou, WS; Song, P; Xu, J; Yin, YL; Zhu, ML1
Jia, H; Jiang, C; Li, Z; Liu, J; Qi, Z; Tang, Y; Zhang, W1
Cao, J; Fu, X; Li, L; You, J; Zhang, Y1
Bai, N; Cheng, JC; Francis, GA; Hiraiwa, K; Miyata, R; Sin, DD; Van Eeden, SF; Vincent, R1
Alderson, P; Lewis, SR; Nicholson, A; Sanders, RD; Smith, AF1
Baumgarten, G; Frede, S; Hilbert, T; Hoeft, A; Klaschik, S; Knuefermann, P; Poth, J1
Fraemohs, L; Hackeng, TM; Koenen, RR; Schmitt, MM; Weber, C1
He, H; Liu, J; Liu, L; Zhang, M; Zhang, S; Zhang, W2
Calhoun, LN; DeBose-Boyd, RA; Engelking, L; Garland, K; Hartman, IZ; Hwang, S; McDonald, J; Mitsche, MA; Xu, F; Young, GA1
Avello L, M; Bravo D, M; Calvo M, C; Mennickent C, S1
Berkowitz, DE; Bhunia, A; Chang, F; Romer, LH; Ryoo, S; Shoukas, A1
Buers, I; Engel, T; Hofnagel, O; Robenek, H; Severs, NJ1
Choi, MS; Ha, TY; McGregor, RA; Shin, SK1
Boettger, T; Boon, RA; Braun, T; Dimmeler, S; Frangakis, AS; Hergenreider, E; Heydt, S; Horrevoets, AJ; Mayr, M; Scheffer, MP; Tréguer, K; Urbich, C; Yin, X; Zeiher, AM1
Ames, BD; Bruegger, J; Li, JW; Ma, S; Nguyen, C; Smith, P; Tang, Y; Tsai, SC; Vederas, JC; Wong, E; Wong, S; Xie, X; Xu, W1
Lan, XH; Li, X; Xu, R; Zhou, YG1
Hsu, YW; Hung, YP; Lee, CL; Pan, TM1
Dong, J; Fujii, S; Furumoto, T; Goto, D; Imagawa, S; Kitabatake, A; Li, H; Nakabayashi, H; Nishi, S; Sakai, M; Zaman, TA1
Rosenson, RS1
Cannon, CP; Ray, KK1
Crock, LW; Sethy-Coraci, I; Silverstein, SC1
Hung, HK; Lee, CL; Pan, TM; Wang, JJ1
Angri, V; CalabrĂ², P; Chiariello, M; Cirillo, P; De Rosa, S; Fiorentino, I; Gargiulo, A; Musto D'Amore, S; Pacileo, M; Petrillo, G; Prevete, N; Sasso, L; Ucci, G1
Frisinghelli, A; Mafrici, A1

Reviews

6 review(s) available for lovastatin and Atherogenesis

ArticleYear
Red Yeast Rice for the Improvement of Lipid Profiles in Mild-to-Moderate Hypercholesterolemia: A Narrative Review.
    Nutrients, 2023, May-12, Volume: 15, Issue:10

    Topics: Anticholesteremic Agents; Atherosclerosis; Biological Products; Cholesterol; Cholesterol, LDL; Dietary Supplements; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipidemias; Lovastatin

2023
Perioperative statin therapy for improving outcomes during and after noncardiac vascular surgery.
    The Cochrane database of systematic reviews, 2013, Jul-03, Issue:7

    Topics: Adult; Angioplasty; Atherosclerosis; Atorvastatin; Cardiovascular Diseases; Cause of Death; Cholestyramine Resin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Perioperative Care; Postoperative Complications; Pyrroles; Randomized Controlled Trials as Topic; Sitosterols; Vascular Surgical Procedures

2013
[Pleiotropic effects of statins].
    Revista medica de Chile, 2008, Volume: 136, Issue:6

    Topics: Anticholesteremic Agents; Antioxidants; Atherosclerosis; Atorvastatin; Endothelium, Vascular; Fatty Acids, Monounsaturated; Fluorobenzenes; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Oxidative Stress; Pravastatin; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Sulfonamides

2008
Low high-density lipoprotein cholesterol disorders and cardiovascular risk: contribution of associated low-density lipoprotein subclass abnormalities.
    Current opinion in cardiology, 2005, Volume: 20, Issue:4

    Topics: Atherosclerosis; Cardiovascular Diseases; Cholesterol; Cholesterol, HDL; Gemfibrozil; Humans; Hypolipidemic Agents; Lipoproteins, LDL; Lovastatin; Risk Factors; Simvastatin

2005
Optimal goals for statin use in patients with coronary artery disease.
    Current opinion in cardiology, 2005, Volume: 20, Issue:6

    Topics: Atherosclerosis; C-Reactive Protein; Cholesterol, LDL; Coronary Disease; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Pravastatin; Treatment Outcome

2005
Regression or reduction in progression of atherosclerosis, and avoidance of coronary events, with lovastatin in patients with or at high risk of cardiovascular disease: a review.
    Clinical drug investigation, 2007, Volume: 27, Issue:9

    Topics: Adult; Atherosclerosis; Cardiovascular Diseases; Clinical Trials as Topic; Coronary Disease; Disease Progression; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Middle Aged; Research Design; Risk Assessment; Risk Factors; Treatment Outcome

2007

Other Studies

23 other study(ies) available for lovastatin and Atherogenesis

ArticleYear
A study of lovastatin and L-arginine co-loaded PLGA nanomedicine for enhancing nitric oxide production and eNOS expression.
    Journal of materials chemistry. B, 2022, 01-26, Volume: 10, Issue:4

    Topics: Animals; Arginine; Atherosclerosis; Cells, Cultured; Humans; Lovastatin; Male; Materials Testing; Mice; Mice, Inbred C57BL; Nanomedicine; Nitric Oxide; Nitric Oxide Synthase Type III; Polylactic Acid-Polyglycolic Acid Copolymer

2022
Modulatory action of withaferin-A on oxidative damage through regulation of inflammatory mediators and apoptosis via PI3K/AKT signaling pathway in high cholesterol-induced atherosclerosis in experimental rats.
    Journal of biochemical and molecular toxicology, 2022, Volume: 36, Issue:10

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Atherosclerosis; Caspase 3; Cholesterol; Cytokines; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Inflammation Mediators; Lovastatin; Male; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Receptors, Tumor Necrosis Factor; Signal Transduction

2022
Evaluation of the Combined Effect of Recombinant High-Density Lipoprotein Carrier and the Encapsulated Lovastatin in RAW264.7 Macrophage Cells Based on the Median-Effect Principle.
    Molecular pharmaceutics, 2018, 03-05, Volume: 15, Issue:3

    Topics: Animals; Anticholesteremic Agents; Atherosclerosis; Cholesterol; Drug Carriers; Drug Combinations; Drug Compounding; Drug Synergism; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Lovastatin; Mice; Nanoparticles; RAW 264.7 Cells; Recombinant Proteins

2018
Citronellal prevents endothelial dysfunction and atherosclerosis in rats.
    Journal of cellular biochemistry, 2019, Volume: 120, Issue:3

    Topics: Acetylcholine; Acyclic Monoterpenes; Aldehydes; Animals; Anticholesteremic Agents; Aromatherapy; Atherosclerosis; Balloon Occlusion; Carotid Arteries; Cell Movement; Cholecalciferol; Diet, High-Fat; Endothelial Cells; Gene Expression; Humans; Lovastatin; Male; Oxidative Stress; Plaque, Atherosclerotic; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchanger 1; Vasodilation

2019
Rational Design of Lovastatin-Loaded Spherical Reconstituted High Density Lipoprotein for Efficient and Safe Anti-Atherosclerotic Therapy.
    Molecular pharmaceutics, 2019, 07-01, Volume: 16, Issue:7

    Topics: Animals; Atherosclerosis; Cell Survival; Drug Carriers; Drug Compounding; Drug Synergism; Erythrocytes; Hemolysis; Lipoproteins, HDL; Lovastatin; Matrix Metalloproteinases; Mice; Mice, Knockout, ApoE; Nanospheres; Optical Imaging; Plaque, Atherosclerotic; Rabbits; RAW 264.7 Cells; Treatment Outcome

2019
Effect of 7-difluoromethyl-5, 4'-dimethoxygenistein on aorta atherosclerosis in hyperlipidemia ApoE(-/-) mice induced by a cholesterol-rich diet.
    Drug design, development and therapy, 2013, Volume: 7

    Topics: Animals; Aorta, Thoracic; Apolipoproteins E; Atherosclerosis; Diet, High-Fat; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Genistein; Hyperlipidemias; Lipids; Lovastatin; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitrites; Vasodilation; von Willebrand Factor

2013
Statins attenuate the development of atherosclerosis and endothelial dysfunction induced by exposure to urban particulate matter (PM10).
    Toxicology and applied pharmacology, 2013, Oct-01, Volume: 272, Issue:1

    Topics: Animals; Atherosclerosis; Blood Vessels; Cholesterol, Dietary; Cyclooxygenase 2; Cytokines; Endothelin-1; Endothelins; Endothelium, Vascular; Environmental Exposure; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Lipids; Lovastatin; Male; Nitric Oxide Synthase Type II; Particulate Matter; Plaque, Atherosclerotic; Rabbits; Reactive Oxygen Species; Urban Health; Vascular Diseases

2013
Anti-atherogenic effects of statins: Impact on angiopoietin-2 release from endothelial cells.
    Biochemical pharmacology, 2013, Nov-15, Volume: 86, Issue:10

    Topics: Acyl Coenzyme A; Angiopoietin-2; Atherosclerosis; Cell Survival; Cells, Cultured; Endothelial Cells; Exocytosis; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Nitric Oxide; Nitric Oxide Synthase Type III; Pravastatin; Simvastatin; Weibel-Palade Bodies

2013
Atherogenic mononuclear cell recruitment is facilitated by oxidized lipoprotein-induced endothelial junctional adhesion molecule-A redistribution.
    Atherosclerosis, 2014, Volume: 234, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Apolipoproteins E; Atherosclerosis; Cell Adhesion Molecules; Cells, Cultured; Coculture Techniques; Endothelial Cells; Humans; Inflammation; Inflammation Mediators; Leukocyte Rolling; Leukocytes, Mononuclear; Lipoproteins, LDL; Lovastatin; Mice; Mice, Knockout; Permeability; Pioglitazone; Protein Transport; Receptors, Cell Surface; RNA Interference; Signal Transduction; Thiazolidinediones; Transendothelial and Transepithelial Migration; Transfection

2014
Hyaluronic acid-decorated reconstituted high density lipoprotein targeting atherosclerotic lesions.
    Biomaterials, 2014, Volume: 35, Issue:27

    Topics: Animals; Aorta, Thoracic; Atherosclerosis; Disease Models, Animal; Drug Carriers; Fluorescent Antibody Technique; Hyaluronic Acid; Lipoproteins, HDL; Lovastatin; Macrophages; Male; Matrix Metalloproteinase 9; Nanostructures; Particle Size; Rabbits; Static Electricity; Tissue Distribution

2014
Suppression of Remodeling Behaviors with Arachidonic Acid Modification for Enhanced in vivo Antiatherogenic Efficacies of Lovastatin-loaded Discoidal Recombinant High Density Lipoprotein.
    Pharmaceutical research, 2015, Volume: 32, Issue:10

    Topics: Animals; Arachidonic Acid; Atherosclerosis; Cholesterol; Drug Carriers; Drug Delivery Systems; Lipoproteins, HDL; Lovastatin; Macrophages; Male; Matrix Metalloproteinase 9; Phosphatidylcholine-Sterol O-Acyltransferase; Rabbits

2015
Contribution of Accelerated Degradation to Feedback Regulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase and Cholesterol Metabolism in the Liver.
    The Journal of biological chemistry, 2016, Jun-24, Volume: 291, Issue:26

    Topics: Animals; Atherosclerosis; Cells, Cultured; Cholesterol; Hydroxymethylglutaryl CoA Reductases; Liver; Lovastatin; Mice; Mice, Knockout; Protein Structure, Tertiary; Proteolysis

2016
OxLDL-dependent activation of arginase II is dependent on the LOX-1 receptor and downstream RhoA signaling.
    Atherosclerosis, 2011, Volume: 214, Issue:2

    Topics: Animals; Arginase; Atherosclerosis; Cells, Cultured; Cholesterol, Dietary; Endothelial Cells; Enzyme Activation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins, LDL; Lovastatin; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microtubules; Nitric Oxide; Protein Transport; rhoA GTP-Binding Protein; RNA Interference; Scavenger Receptors, Class E; Signal Transduction; Simvastatin; Superoxides; Transfection

2011
SR-PSOX at sites predisposed to atherosclerotic lesion formation mediates monocyte-endothelial cell adhesion.
    Atherosclerosis, 2011, Volume: 217, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Atherosclerosis; Cell Adhesion; Cells, Cultured; Chemokine CXCL16; Chemokines, CXC; Coculture Techniques; Cytokines; Disease Models, Animal; Human Umbilical Vein Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Immunohistochemistry; Inflammation Mediators; Lovastatin; Macrophages; Monocytes; Rabbits; Receptors, Scavenger; Thiazolidinediones

2011
Long-term curcumin administration protects against atherosclerosis via hepatic regulation of lipoprotein cholesterol metabolism.
    Molecular nutrition & food research, 2011, Volume: 55, Issue:12

    Topics: Acetyl-CoA C-Acetyltransferase; Animals; Apolipoprotein A-I; Apolipoproteins B; Atherosclerosis; Cholesterol; Cholesterol, Dietary; Cholesterol, HDL; Cholesterol, LDL; Curcumin; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intercellular Adhesion Molecule-1; Lipid Metabolism; Lipoproteins; Liver; Liver X Receptors; Lovastatin; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Orphan Nuclear Receptors; PPAR alpha; Triglycerides; Up-Regulation; Vascular Cell Adhesion Molecule-1

2011
Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs.
    Nature cell biology, 2012, Feb-12, Volume: 14, Issue:3

    Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Cells, Cultured; Coculture Techniques; Endothelial Cells; Exosomes; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Kruppel-Like Transcription Factors; Lovastatin; Mice; Mice, Knockout; MicroRNAs; Microscopy, Confocal; Microscopy, Electron; Myocytes, Smooth Muscle; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Stress, Mechanical; Transfection

2012
Crystal structure and biochemical studies of the trans-acting polyketide enoyl reductase LovC from lovastatin biosynthesis.
    Proceedings of the National Academy of Sciences of the United States of America, 2012, Jul-10, Volume: 109, Issue:28

    Topics: Aspergillus; Atherosclerosis; Candida tropicalis; Catalytic Domain; Chromatography, Gel; Crystallography, X-Ray; Humans; Lovastatin; Molecular Conformation; Mutation; NADP; Polyketide Synthases; Protein Conformation; Protein Structure, Quaternary; Protein Structure, Tertiary; Static Electricity; Stereoisomerism; Substrate Specificity; Transcriptional Activation

2012
[Effects of three different treatments on atherosclerosis and adipose in rats].
    Zhonghua yi xue za zhi, 2012, Jun-19, Volume: 92, Issue:23

    Topics: Adipose Tissue; Animals; Aspirin; Atherosclerosis; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Combination; Lovastatin; Male; Probucol; Rats; Rats, Sprague-Dawley

2012
Monascin and ankaflavin have more anti-atherosclerosis effect and less side effect involving increasing creatinine phosphokinase activity than monacolin K under the same dosages.
    Journal of agricultural and food chemistry, 2013, Jan-09, Volume: 61, Issue:1

    Topics: Animals; Aorta; Atherosclerosis; Creatine Kinase; Cricetinae; Flavins; Heterocyclic Compounds, 3-Ring; Lipid Peroxidation; Lipids; Liver Function Tests; Lovastatin; Male; Mesocricetus

2013
Interleukin-6 and mevastatin regulate plasminogen activator inhibitor-1 through CCAAT/enhancer-binding protein-delta.
    Arteriosclerosis, thrombosis, and vascular biology, 2005, Volume: 25, Issue:5

    Topics: Animals; Atherosclerosis; Carcinoma, Hepatocellular; CCAAT-Enhancer-Binding Protein-delta; Cell Line, Tumor; Cell Nucleus; Chromosome Mapping; Gene Expression; Hepatocytes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-6; Liver Neoplasms; Lovastatin; Mice; Mice, Inbred ICR; Mutagenesis, Site-Directed; Plasminogen Activator Inhibitor 1; Promoter Regions, Genetic; Response Elements; RNA, Messenger; Thrombosis; Transfection

2005
PAF-receptor antagonists, lovastatin, and the PTK inhibitor genistein inhibit H2O2 secretion by macrophages cultured on oxidized-LDL matrices.
    Journal of leukocyte biology, 2005, Volume: 78, Issue:5

    Topics: Atherosclerosis; Cells, Cultured; Extracellular Matrix; Genistein; Humans; Hydrogen Peroxide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins, LDL; Lovastatin; Macrophages; Phagocytes; Platelet Membrane Glycoproteins; Protein-Tyrosine Kinases; Receptors, G-Protein-Coupled; Time Factors

2005
Red mold dioscorea has greater hypolipidemic and antiatherosclerotic effect than traditional red mold rice and unfermented dioscorea in hamsters.
    Journal of agricultural and food chemistry, 2007, Aug-22, Volume: 55, Issue:17

    Topics: Animals; Atherosclerosis; Cricetinae; Diet; Dioscorea; Fermentation; Hypolipidemic Agents; Lipids; Lovastatin; Male; Mesocricetus; Monascus; Oryza

2007
HMG-CoA reductase inhibitors reduce nicotine-induced expression of cellular adhesion molecules in cultured human coronary endothelial cells.
    Journal of vascular research, 2007, Volume: 44, Issue:6

    Topics: Atherosclerosis; Cell Adhesion; Cells, Cultured; Coronary Vessels; Dose-Response Relationship, Drug; Endothelial Cells; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Intercellular Adhesion Molecule-1; Leukocytes; Lovastatin; NF-kappa B; Nicotine; Nicotinic Agonists; Pravastatin; Protein Kinase C; Reactive Oxygen Species; rhoA GTP-Binding Protein; RNA, Messenger; Signal Transduction; Simvastatin; Smoking; Superoxide Dismutase; Time Factors; Vascular Cell Adhesion Molecule-1

2007