lovastatin has been researched along with Allergic Encephalomyelitis in 15 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (6.67) | 18.2507 |
2000's | 12 (80.00) | 29.6817 |
2010's | 2 (13.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Choi, S; Samuvel, DJ; Saxena, N; Singh, AK; Singh, I; Won, J | 1 |
Paintlia, AS; Paintlia, MK; Singh, AK; Singh, I; Skoff, RB | 1 |
Paintlia, AS; Paintlia, MK; Singh, AK; Singh, I | 3 |
Hollis, BW; Paintlia, AS; Paintlia, MK; Singh, AK; Singh, I | 1 |
Gilg, AG; Singh, AK; Singh, I; Stanislaus, R | 1 |
Adamson, P; Baker, D; Beraud, E; Greenwood, J; Kanuga, N; Pryce, G; Walters, CE | 1 |
Blezer, EL; de Vries, HE; Dijkstra, CD; Döpp, E; Floris, S; Nicolay, K; Schadee-Eestermans, IL; Schreibelt, G; van der Pol, SM | 1 |
Giri, S; Nath, N; Prasad, R; Singh, AK; Singh, I | 1 |
Barbosa, E; Gilg, AG; Paintlia, AS; Paintlia, MK; Singh, AK; Singh, I; Stanislaus, R | 1 |
Contreras, MA; Haq, E; Khan, M; Paintlia, AS; Paintlia, MK; Singh, AK; Singh, I; Stanislaus, R | 1 |
Khan, M; Paintlia, AS; Paintlia, MK; Singh, AK; Singh, I; Vollmer, T | 1 |
Pahan, K; Singh, AK; Singh, I; Stanislaus, R | 1 |
Singh, AK; Singh, I; Stanislaus, R | 1 |
15 other study(ies) available for lovastatin and Allergic Encephalomyelitis
Article | Year |
---|---|
Combination therapy of lovastatin and AMP-activated protein kinase activator improves mitochondrial and peroxisomal functions and clinical disease in experimental autoimmune encephalomyelitis model.
Topics: Adenosine Triphosphate; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Biomarkers; Cell Line; Cytokines; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Gene Expression; Humans; Lovastatin; Mice; Mitochondria; Peroxisomes; rho-Associated Kinases; rhoA GTP-Binding Protein; Ribonucleotides; Spinal Cord | 2018 |
Combination therapy of lovastatin and rolipram provides neuroprotection and promotes neurorepair in inflammatory demyelination model of multiple sclerosis.
Topics: Animals; Central Nervous System; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Encephalomyelitis, Autoimmune, Experimental; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunologic Factors; Lovastatin; Nerve Fibers, Myelinated; Nerve Regeneration; Neuroprotective Agents; Phosphodiesterase Inhibitors; Rats; Rats, Inbred Lew; Rolipram; Treatment Outcome; Wallerian Degeneration | 2009 |
Combined medication of lovastatin with rolipram suppresses severity of experimental autoimmune encephalomyelitis.
Topics: Animals; Demyelinating Diseases; Drug Synergism; Drug Therapy, Combination; Encephalomyelitis, Autoimmune, Experimental; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immune Tolerance; Lovastatin; Nerve Degeneration; Phosphodiesterase Inhibitors; Rats; Rats, Inbred Lew; Rolipram; Severity of Illness Index; T-Lymphocytes, Regulatory; Th1 Cells; Th2 Cells | 2008 |
Interference with RhoA-ROCK signaling mechanism in autoreactive CD4+ T cells enhances the bioavailability of 1,25-dihydroxyvitamin D3 in experimental autoimmune encephalomyelitis.
Topics: 25-Hydroxyvitamin D3 1-alpha-Hydroxylase; Animals; Biological Availability; Biosynthetic Pathways; Calcitriol; CD4-Positive T-Lymphocytes; Encephalomyelitis, Autoimmune, Experimental; Female; Guinea Pigs; Immunosuppression Therapy; Inflammation; Lovastatin; Lymphoid Tissue; Mevalonic Acid; Protein Kinase Inhibitors; Rats; Rats, Inbred Lew; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Spinal Cord; Steroid Hydroxylases; Vitamin D; Vitamin D3 24-Hydroxylase | 2012 |
Immunomodulation of experimental autoimmune encephalomyelitis in the Lewis rats by Lovastatin.
Topics: Animals; Cell Culture Techniques; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Enzyme-Linked Immunosorbent Assay; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interferon-gamma; Interleukin-10; Interleukin-6; Lovastatin; Myelin Basic Protein; Nitrites; Phytohemagglutinins; Rats; Rats, Inbred Lew; Spleen | 2002 |
Lovastatin inhibits brain endothelial cell Rho-mediated lymphocyte migration and attenuates experimental autoimmune encephalomyelitis.
Topics: Animals; Brain; Cell Movement; Coculture Techniques; Dose-Response Relationship, Drug; Encephalomyelitis, Autoimmune, Experimental; Endothelium, Vascular; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Lymphocytes; Mice; Remission Induction; rho GTP-Binding Proteins; Secondary Prevention | 2003 |
Blood-brain barrier permeability and monocyte infiltration in experimental allergic encephalomyelitis: a quantitative MRI study.
Topics: Animals; Blood-Brain Barrier; Brain; Capillary Permeability; Cell Movement; Contrast Media; Dextrans; Encephalomyelitis, Autoimmune, Experimental; Ferrosoferric Oxide; Gadolinium DTPA; Image Processing, Computer-Assisted; Immunohistochemistry; Iron; Lovastatin; Magnetic Resonance Imaging; Magnetite Nanoparticles; Male; Microscopy, Electron; Monocytes; Oxides; Rats; Rats, Inbred Lew; Spinal Cord | 2004 |
Potential targets of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor for multiple sclerosis therapy.
Topics: Animals; Cell Differentiation; Cell Line; Cell Migration Inhibition; Cell Movement; DNA-Binding Proteins; Encephalomyelitis, Autoimmune, Experimental; Epitopes, T-Lymphocyte; Female; GATA3 Transcription Factor; Growth Inhibitors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Injections, Intraperitoneal; Interphase; Lovastatin; Mice; Mice, Inbred Strains; Multiple Sclerosis; Myelin Proteolipid Protein; Neurons; Spinal Cord; T-Box Domain Proteins; T-Lymphocyte Subsets; Th1 Cells; Th2 Cells; Trans-Activators; Transcription Factors; Up-Regulation | 2004 |
Regulation of gene expression associated with acute experimental autoimmune encephalomyelitis by Lovastatin.
Topics: Animals; Cytokines; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Gene Expression Regulation; Genes, MHC Class II; Growth Substances; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Multiple Sclerosis; Oligonucleotide Array Sequence Analysis; Rats; Rats, Inbred Lew; RNA, Messenger; Severity of Illness Index; Spinal Cord; Transcription Factors; Up-Regulation | 2004 |
Impaired peroxisomal function in the central nervous system with inflammatory disease of experimental autoimmune encephalomyelitis animals and protection by lovastatin treatment.
Topics: Acyl-CoA Oxidase; Acyltransferases; Adenosine Triphosphatases; Animals; Anticholesteremic Agents; ATP-Binding Cassette Transporters; ATPases Associated with Diverse Cellular Activities; Catalase; Central Nervous System; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Fatty Acids; Female; Freund's Adjuvant; Immunohistochemistry; Inflammation; Lovastatin; Membrane Proteins; Microarray Analysis; Peroxisomal Disorders; Peroxisomes; Rats; Rats, Inbred Lew; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2004 |
HMG-CoA reductase inhibitor augments survival and differentiation of oligodendrocyte progenitors in animal model of multiple sclerosis.
Topics: Animals; Cell Differentiation; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Multiple Sclerosis; Myelin Sheath; Oligodendroglia; Rats; Rats, Inbred Lew; Stem Cells | 2005 |
Immunomodulatory effect of combination therapy with lovastatin and 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside alleviates neurodegeneration in experimental autoimmune encephalomyelitis.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Therapy, Combination; Encephalomyelitis, Autoimmune, Experimental; Enzyme Activation; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Immunoglobulin G; Immunologic Factors; Lovastatin; Multienzyme Complexes; Multiple Sclerosis; Myelin Basic Protein; Protein Serine-Threonine Kinases; Rats; Rats, Inbred Lew; Ribonucleotides; Th1 Cells; Th2 Cells | 2006 |
Inhibition of rho family functions by lovastatin promotes myelin repair in ameliorating experimental autoimmune encephalomyelitis.
Topics: Animals; Benzamides; Cell Differentiation; Cell Proliferation; Cells, Cultured; Cholesterol; Encephalomyelitis, Autoimmune, Experimental; Female; Hydroxymethylglutaryl CoA Reductases; Inflammation; Lovastatin; Methionine; Mevalonic Acid; Myelin Sheath; Nerve Growth Factors; Neuroglia; Oligodendroglia; Polyisoprenyl Phosphates; ras Proteins; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; rho GTP-Binding Proteins; Spinal Cord; Wound Healing | 2008 |
Amelioration of experimental allergic encephalomyelitis in Lewis rats by lovastatin.
Topics: Animals; Encephalomyelitis, Autoimmune, Experimental; Female; Fluorescent Antibody Technique; Interferon-gamma; Lovastatin; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Inbred Lew; Tumor Necrosis Factor-alpha | 1999 |
Lovastatin treatment decreases mononuclear cell infiltration into the CNS of Lewis rats with experimental allergic encephalomyelitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Adhesion; Chemotaxis, Leukocyte; Cytokines; Demyelinating Diseases; Disease Models, Animal; Drug Evaluation, Preclinical; Encephalomyelitis, Autoimmune, Experimental; Endothelium, Vascular; Enzyme Induction; Female; Gene Expression Regulation; Intercellular Adhesion Molecule-1; Lovastatin; Lymphocyte Function-Associated Antigen-1; Monocytes; Multiple Sclerosis; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Inbred Lew; Spinal Cord | 2001 |