Page last updated: 2024-08-23

lovastatin and Age-Related Osteoporosis

lovastatin has been researched along with Age-Related Osteoporosis in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (17.65)18.2507
2000's6 (35.29)29.6817
2010's6 (35.29)24.3611
2020's2 (11.76)2.80

Authors

AuthorsStudies
Guo, HF; He, XB; Li, X; Li, ZR; Liu, ZY; Shao, HY; Si, SY; Yang, ZY; Zhang, YQ1
Guo, HF; He, XB; Jiang, JD; Li, X; Li, ZR; Liu, ZY; Shao, HY; Si, SY; Xue, ST; Yang, ZY; Zhang, YQ1
Guo, HF; Jin, J; Ju, DH; Li, ZR; Liu, MJ; Liu, ZY; Xue, ST1
Guo, HF; Jin, J; Li, ZR; Liu, ZY; Xie, ZS; Xue, ST; Yi, H; Zhang, L1
Hu, J; Li, T; Liu, X; Sun, F; Wang, D; Wang, F; Yang, X; Ye, X1
Kaleağasıoğlu, F; Olcay, E; Onur, R1
Abdul-Majeed, S; Mohamed, N; Soelaiman, IN1
Ibrahim, N'; Mohamed, N; Shuid, AN; Soelaiman, IN1
Chang, SP; Chiang, SS; Pan, TM1
Gonyeau, MJ1
Jadhav, SB; Jain, GK1
Chung, KC; Shen, WJ; Wang, GJ1
Boyce, B; Chan, J; Chen, D; Garrett, R; Gutierrez, G; Harris, S; Mundy, G; Rossini, G; Zhao, M1
Vogel, G1
Abe, K; Asami, S; Kodama, T; Konishi, K; Oikawa, S; Sugiyama, M1
Davignon, J; Mabile, L1
Yoneda, T1

Reviews

4 review(s) available for lovastatin and Age-Related Osteoporosis

ArticleYear
Statins and osteoporosis: a clinical review.
    Pharmacotherapy, 2005, Volume: 25, Issue:2

    Topics: Aged; Bone and Bones; Bone Density; Clinical Trials as Topic; Female; Fractures, Bone; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Middle Aged; Osteogenesis; Osteoporosis; Simvastatin; Treatment Outcome; United States

2005
Statins and osteoporosis: new role for old drugs.
    The Journal of pharmacy and pharmacology, 2006, Volume: 58, Issue:1

    Topics: Animals; Atorvastatin; Bone and Bones; Clinical Trials as Topic; Drug Delivery Systems; Fatty Acids, Monounsaturated; Fluorobenzenes; Fluvastatin; Fractures, Bone; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Liver; Lovastatin; Osteogenesis; Osteoporosis; Pharmacokinetics; Pravastatin; Pyridines; Pyrimidines; Pyrroles; Quinolines; Rosuvastatin Calcium; Simvastatin; Sulfonamides

2006
[Mechanisms of action of statins and their pleiotropic effects].
    Annales d'endocrinologie, 2001, Volume: 62, Issue:1 Pt 2

    Topics: Arteriosclerosis; Cell Division; Endothelium, Vascular; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Lovastatin; Neoplasms; Osteoporosis

2001
[Stimulation of bone formation by anti-hyperlipidemic agent statins and its mechanism of action].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 3

    Topics: Animals; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Indoles; Lovastatin; Mevalonic Acid; Osteogenesis; Osteoporosis; Stimulation, Chemical; Transforming Growth Factor beta

2002

Other Studies

13 other study(ies) available for lovastatin and Age-Related Osteoporosis

ArticleYear
Synthesis and evaluation of 1-(benzo[b]thiophen-2-yl)ethanone analogues as novel anti-osteoporosis agents acting on BMP-2 promotor.
    Bioorganic & medicinal chemistry letters, 2009, Aug-01, Volume: 19, Issue:15

    Topics: Animals; Bone and Bones; Bone Morphogenetic Protein 2; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Drug Design; Female; Gene Expression Regulation; Humans; Mice; Models, Chemical; Osteoporosis; Ovariectomy; Promoter Regions, Genetic; Rats; Thiophenes

2009
Substituted benzothiophene or benzofuran derivatives as a novel class of bone morphogenetic protein-2 up-regulators: synthesis, structure-activity relationships, and preventive bone loss efficacies in senescence accelerated mice (SAMP6) and ovariectomized
    Journal of medicinal chemistry, 2010, Feb-25, Volume: 53, Issue:4

    Topics: Anabolic Agents; Animals; Benzofurans; Bone Density; Bone Density Conservation Agents; Bone Morphogenetic Protein 2; Cell Line; Female; Lethal Dose 50; Male; Mice; Osteoporosis; Ovariectomy; Rats; Stereoisomerism; Structure-Activity Relationship; Thiophenes; Up-Regulation

2010
Synthesis of a novel class of substituted benzothiophene or benzofuran derivatives as BMP-2 up-regulators and evaluation of the BMP-2-up-regulating effects in vitro and the effects on glucocorticoid-induced osteoporosis in rats.
    European journal of medicinal chemistry, 2015, Volume: 96

    Topics: Animals; Benzofurans; Bone Morphogenetic Protein 2; Cell Line; Female; Glucocorticoids; Male; Mice; Mice, Inbred Strains; Osteoporosis; Rats; Rats, Wistar; Thiophenes; Up-Regulation

2015
Substituted benzothiophene and benzofuran derivatives as a novel class of bone morphogenetic Protein-2 upregulators: Synthesis, anti-osteoporosis efficacies in ovariectomized rats and a zebrafish model, and ADME properties.
    European journal of medicinal chemistry, 2020, Aug-15, Volume: 200

    Topics: Animals; Benzofurans; Bone Morphogenetic Protein 2; Caco-2 Cells; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Mice; Mice, Inbred BALB C; Molecular Structure; Osteoporosis; Ovariectomy; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thiophenes; Zebrafish

2020
Controlling sustained statins release in multi-layered composite scaffolds for healing of osteoporotic bone defects.
    Biomaterials advances, 2022, Volume: 137

    Topics: Animals; Bone and Bones; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Osteoporosis; Rabbits; Tissue Scaffolds

2022
Statins as potential agents for the prevention and treatment of osteoporosis.
    Endocrine, 2018, Volume: 62, Issue:1

    Topics: Animals; Atorvastatin; Bone Density; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Osteoporosis; Rats; Simvastatin

2018
The use of delta-tocotrienol and lovastatin for anti-osteoporotic therapy.
    Life sciences, 2015, Mar-15, Volume: 125

    Topics: Animals; Drug Synergism; Female; Femur; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Osteogenesis; Osteoporosis; Ovariectomy; Rats; Rats, Sprague-Dawley; Vitamin E

2015
The Effects of Targeted Deliveries of Lovastatin and Tocotrienol on Ossification-Related Gene Expressions in Fracture Healing in an Osteoporosis Rat Model.
    International journal of environmental research and public health, 2015, Oct-16, Volume: 12, Issue:10

    Topics: Animals; Bone Development; Disease Models, Animal; Drug Administration Routes; Drug Therapy, Combination; Estrogens; Estrogens, Conjugated (USP); Female; Fracture Healing; Gene Expression; Lovastatin; Osteoporosis; Ovariectomy; Rats; Rats, Sprague-Dawley; Tocotrienols

2015
Osteoprotective effect of Monascus-fermented dioscorea in ovariectomized rat model of postmenopausal osteoporosis.
    Journal of agricultural and food chemistry, 2011, Sep-14, Volume: 59, Issue:17

    Topics: Animals; Bone Density; Dioscorea; Diosgenin; Disease Models, Animal; Female; Fermentation; Flavins; Glycine max; Heterocyclic Compounds, 3-Ring; Isoflavones; Lovastatin; Monascus; Osteoporosis; Ovariectomy; Phytoestrogens; Plant Roots; Rats; Rats, Sprague-Dawley

2011
Lipid clearing agents in steroid-induced osteoporosis.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 1995, Volume: 94, Issue:10

    Topics: Animals; Anticholesteremic Agents; Bezafibrate; Glucocorticoids; Hypolipidemic Agents; Lovastatin; Methylprednisolone; Osteoporosis; Rabbits

1995
Stimulation of bone formation in vitro and in rodents by statins.
    Science (New York, N.Y.), 1999, Dec-03, Volume: 286, Issue:5446

    Topics: Animals; Bone Density; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Cell Line; Female; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Mice; Mice, Inbred ICR; Organ Culture Techniques; Osteoblasts; Osteoclasts; Osteogenesis; Osteoporosis; Ovariectomy; Promoter Regions, Genetic; Rats; Recombinant Proteins; Simvastatin; Skull; Transfection; Transforming Growth Factor beta

1999
Cholesterol-lowering drugs may boost bones.
    Science (New York, N.Y.), 1999, Dec-03, Volume: 286, Issue:5446

    Topics: Animals; Anticholesteremic Agents; Bone Density; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Clinical Trials as Topic; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mice; Osteogenesis; Osteoporosis; Rats; Simvastatin; Transforming Growth Factor beta

1999
Compactin and simvastatin, but not pravastatin, induce bone morphogenetic protein-2 in human osteosarcoma cells.
    Biochemical and biophysical research communications, 2000, May-19, Volume: 271, Issue:3

    Topics: Anti-Bacterial Agents; Bone Morphogenetic Protein 2; Bone Morphogenetic Protein 4; Bone Morphogenetic Proteins; Bone Neoplasms; Cloning, Molecular; Disulfides; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Indole Alkaloids; Lovastatin; Mevalonic Acid; Osteoporosis; Osteosarcoma; Pravastatin; Promoter Regions, Genetic; RNA, Messenger; Simvastatin; Transfection; Transforming Growth Factor beta; Tumor Cells, Cultured

2000