Compounds > lovastatin
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lovastatin and Adrenoleukodystrophy

lovastatin has been researched along with Adrenoleukodystrophy in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (14.29)18.2507
2000's9 (64.29)29.6817
2010's3 (21.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aggarwal, KC; Mittal, A1
Khan, M; Singh, I; Singh, J1
Contreras, MA; Gilg, AG; Singh, I; Uto, T1
de Visser, M; Dijkgraaf, MG; Engelen, M; Hijzen, M; Kemp, S; Ofman, R; Poll-The, BT; van der Wardt, LA; van Geel, BM; Wanders, RJ1
Daley, GQ; Huh, YJ; Hwang, DY; Jang, J; Kang, HC; Kim, DS; Kim, DW; Kim, HS; Kim, JY; Lee, J; Lee, JA; Lim, B; Park, IH; Yoo, JE; Yoon, TM1
Berger, J; Forss-Petter, S; Weinhofer, I; Zigman, M2
Imamura, A; Suzuki, Y1
Bao, XH; Ping, LL; Wang, AH1
Khan, M; Pahan, K; Singh, I1
Key, L; Khan, M; Pai, S; Singh, I1
Barbosa, E; Betros, R; Craver, JR; Curé, JK; Key, LL; Khan, M; Pai, GS; Singh, I1
Alger, S; Green, A; Köhler, W; Moser, H; Sokolowski, P1
Bruckert, E; Girard, S; Turpin, G1

Reviews

2 review(s) available for lovastatin and Adrenoleukodystrophy

ArticleYear
[X-linked adrenoleukodystrophy (ALD)].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl

    Topics: Adrenoleukodystrophy; Age of Onset; ATP Binding Cassette Transporter, Subfamily D, Member 1; ATP-Binding Cassette Transporters; Biomarkers; Bone Marrow Transplantation; Chromosomes, Human, X; Dementia; Diagnosis, Differential; Drug Combinations; Erucic Acids; Fatty Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Magnetic Resonance Imaging; Male; Mutation; Phenylbutyrates; Triolein

2004
[Endocrine disease in adrenoleukodystrophy].
    Annales de medecine interne, 2001, Volume: 152, Issue:1

    Topics: Adrenal Insufficiency; Adrenoleukodystrophy; Adult; Anticholesteremic Agents; Bone Marrow Transplantation; Child; Child, Preschool; Drug Combinations; Erucic Acids; Female; Genetic Therapy; Humans; Lovastatin; Male; Mass Screening; Phenylbutyrates; Testicular Diseases; Treatment Outcome; Triolein

2001

Trials

2 trial(s) available for lovastatin and Adrenoleukodystrophy

ArticleYear
Lovastatin in X-linked adrenoleukodystrophy.
    The New England journal of medicine, 2010, Jan-21, Volume: 362, Issue:3

    Topics: Adrenoleukodystrophy; Cholesterol, LDL; Cross-Over Studies; Double-Blind Method; Fatty Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Pilot Projects

2010
Lovastatin therapy for X-linked adrenoleukodystrophy: clinical and biochemical observations on 12 patients.
    Molecular genetics and metabolism, 2000, Volume: 69, Issue:4

    Topics: Adrenoleukodystrophy; Adult; Aged; Aspartate Aminotransferases; Child; Creatine Kinase; Fatty Acids; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Middle Aged; Platelet Count; Treatment Outcome

2000

Other Studies

10 other study(ies) available for lovastatin and Adrenoleukodystrophy

ArticleYear
Childhood cerebral adrenoleukodystrophy.
    The Indian journal of medical research, 2014, Volume: 140, Issue:2

    Topics: Adrenoleukodystrophy; Blood Chemical Analysis; Brain; Child; Diet, Fat-Restricted; Humans; Hyperpigmentation; Lovastatin; Magnetic Resonance Imaging; Male; Nervous System Diseases

2014
Plasmalogen deficiency in cerebral adrenoleukodystrophy and its modulation by lovastatin.
    Journal of neurochemistry, 2008, Volume: 106, Issue:4

    Topics: Adrenoleukodystrophy; Animals; Cells, Cultured; Cerebrum; Child; Humans; Lovastatin; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Plasmalogens; Rats; Reactive Oxygen Species

2008
Oxidative imbalance in nonstimulated X-adrenoleukodystrophy-derived lymphoblasts.
    Developmental neuroscience, 2008, Volume: 30, Issue:6

    Topics: Adrenoleukodystrophy; Cell Line; Child; Fatty Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-1beta; Lovastatin; Lymphocytes; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; Nitric Oxide; Oxidation-Reduction; Phosphoproteins; Protein Subunits; Reactive Oxygen Species; Tumor Necrosis Factor-alpha

2008
Induced pluripotent stem cell models from X-linked adrenoleukodystrophy patients.
    Annals of neurology, 2011, Volume: 70, Issue:3

    Topics: Adrenoleukodystrophy; ATP Binding Cassette Transporter, Subfamily D; ATP-Binding Cassette Transporters; Brain; Cell Differentiation; DNA; Excitatory Postsynaptic Potentials; Fatty Acids, Nonesterified; Hematopoietic Stem Cell Transplantation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Induced Pluripotent Stem Cells; Lovastatin; Neurons; Oligodendroglia; Phenotype; Phenylbutyrates; Reverse Transcriptase Polymerase Chain Reaction

2011
Cholesterol regulates ABCD2 expression: implications for the therapy of X-linked adrenoleukodystrophy.
    Human molecular genetics, 2002, Oct-15, Volume: 11, Issue:22

    Topics: Adrenoleukodystrophy; Animals; Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily D; ATP Binding Cassette Transporter, Subfamily D, Member 1; ATP-Binding Cassette Transporters; Base Sequence; CCAAT-Enhancer-Binding Proteins; Cell Line; Cells, Cultured; Cholesterol; DNA; DNA-Binding Proteins; Fatty Acids; Gene Expression; Humans; Lovastatin; Mice; Mutagenesis, Site-Directed; Promoter Regions, Genetic; Sterol Regulatory Element Binding Protein 1; Transcription Factors

2002
Cholesterol regulates ABCD2 gene expression: implications for X-linked adrenoleukodstrophy.
    Advances in experimental medicine and biology, 2003, Volume: 544

    Topics: Adrenoleukodystrophy; Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily D; ATP-Binding Cassette Transporters; CCAAT-Enhancer-Binding Proteins; Cholesterol; DNA-Binding Proteins; Fatty Acids; Gene Expression Regulation; Humans; Lovastatin; Male; Sterol Regulatory Element Binding Protein 1; Transcription Factors

2003
[Lovastatin induction of the redundant gene: implications for therapy of X-linked adrenoleukodystrophy].
    Zhonghua er ke za zhi = Chinese journal of pediatrics, 2007, Volume: 45, Issue:4

    Topics: Adrenoleukodystrophy; Humans; Lovastatin

2007
Lovastatin and sodium phenylacetate normalize the levels of very long chain fatty acids in skin fibroblasts of X- adrenoleukodystrophy.
    FEBS letters, 1998, Apr-24, Volume: 426, Issue:3

    Topics: Adrenoleukodystrophy; Cells, Cultured; Drug Synergism; Fatty Acids; Fibroblasts; Gene Deletion; Humans; Intracellular Fluid; Lovastatin; Mevalonic Acid; Oxidation-Reduction; Phenylacetates; Skin; X Chromosome

1998
Lovastatin for X-linked adrenoleukodystrophy.
    The New England journal of medicine, 1998, Sep-03, Volume: 339, Issue:10

    Topics: Adrenoleukodystrophy; Adult; Aged; Fatty Acids; Genetic Linkage; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Middle Aged; X Chromosome

1998
Proceedings of the 4th International Workshop of the Adrenoleukodystrophy International Research Group (ALD-IRG), University of York, 3 September 1998.
    Journal of inherited metabolic disease, 2000, Volume: 23, Issue:5

    Topics: Adrenoleukodystrophy; Adult; Child; Clinical Protocols; Drug Combinations; England; Erucic Acids; Hematopoietic Stem Cell Transplantation; Humans; Hypolipidemic Agents; Lovastatin; Male; Prospective Studies; Retrospective Studies; Triolein

2000