lovastatin has been researched along with Adenocarcinoma in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (54.17) | 18.2507 |
| 2000's | 9 (37.50) | 29.6817 |
| 2010's | 2 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anscher, MS; Chang, MG; Grob, BM; Holdford, D; Mikkelsen, RB; Moghanaki, D; Mukhopadhyay, ND; Rosu, M; Sanyal, A; Skinner, V; Wang, A | 1 |
| Hussein, D; Mo, H | 1 |
| Farrell, T; Hopmans, SN; Liu, C; Rashid, A; Sanli, T; Schultz, C; Singh, G; Tsakiridis, T; Tsiani, E; Wright, J | 1 |
| Ciocca, DR; Cuello Carrión, FD; Gervasoni, SI; Matar, P; Rozados, VR; Scharovsky, OG | 1 |
| Kenna, T; Mattarollo, SR; Nicol, AJ; Nieda, M | 1 |
| Bil, J; Brzezinska, A; Gietka, J; Golab, J; Issat, T; Jakóbisiak, M; Klejman, MP; Koronkiewicz, M; Legat, M; Makowski, M; Nowis, D; Skierski, J; Stoklosa, T; Urbanski, J | 1 |
| Ehehalt, R; Fullekrug, J; Krautter, M; Kulaksiz, H; Sparla, R; Stremmel, W; Zorn, M | 1 |
| Beales, IL; Ogunwobi, OO | 1 |
| Hawk, ET; Viner, JL | 1 |
| Fukaura, Y; Ishikawa, C; Narisawa, T; Tanida, N; Terada, K; Umezawa, A; Yazawa, K | 1 |
| Namiki, M; Nishino, N; Obara, T; Okamura, K; Tanno, S; Ura, H | 1 |
| Bennis, F; Favre, G; Le Gaillard, F; Soula, G | 1 |
| Auclair, M; Biade, S; Dubertret, L; Mazière, C; Mazière, JC; Mora, L; Morlière, P; Santus, R | 1 |
| Broitman, SA; Cerda, SR; Wilkinson, J | 1 |
| Branch, SK; Broitman, SA; Cerda, S; Wilkinson, J | 1 |
| Blaese, RM; Ramsey, WJ; Touraine, RL; Vahanian, N | 1 |
| Cohen, SA; Doerr, RJ; Hordines, J; Mehta, N; Sykes, D | 1 |
| Foster, BA; Ghosh, PM; Ghosh-Choudhury, N; Greenberg, NM; Kreisberg, JI; Mott, GE; Moyer, ML; Thomas, CA | 1 |
| Fawcett, TW; Gorospe, M; Holbrook, NJ; Hudgins, WR; Shack, S | 1 |
| Choi, HJ; Kang, WK; Kim, MM; Kim, WS; Lee, MH; Park, CH; Park, K; Yoon, SS | 1 |
| Akedo, H; Inoue, M; Iwasaki, T; Kusama, T; Matsumoto, Y; Mukai, M; Nakamura, H; Tatsuta, M | 1 |
| Darzynkiewicz, Z; Mikulski, SM; Shogen, K; Viera, A | 1 |
| Nyce, JW; Schulz, S | 1 |
| Albright, E; Field, FJ; Kam, NT; Mathur, S | 1 |
1 trial(s) available for lovastatin and Adenocarcinoma
| Article | Year |
|---|---|
Phase II study of high-dose lovastatin in patients with advanced gastric adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Drug Evaluation; Female; Humans; Lovastatin; Male; Middle Aged; Stomach Neoplasms; Treatment Outcome | 2001 |
23 other study(ies) available for lovastatin and Adenocarcinoma
| Article | Year |
|---|---|
A Phase II Study to Prevent Radiation-induced Rectal Injury With Lovastatin.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Anticholesteremic Agents; Case-Control Studies; Follow-Up Studies; Gastrointestinal Hemorrhage; Humans; Lovastatin; Male; Middle Aged; Prognosis; Prostatic Neoplasms; Radiation Injuries; Radiation Protection; Radiotherapy, Conformal; Rectum | 2018 |
d-δ-Tocotrienol-mediated suppression of the proliferation of human PANC-1, MIA PaCa-2, and BxPC-3 pancreatic carcinoma cells.
Topics: Adenocarcinoma; Apoptosis; Carcinoma, Pancreatic Ductal; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Synergism; Flow Cytometry; G1 Phase; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inhibitory Concentration 50; Lovastatin; Mevalonic Acid; Microscopy, Fluorescence; Pancreatic Neoplasms; Tocotrienols | 2009 |
Lovastatin sensitizes lung cancer cells to ionizing radiation: modulation of molecular pathways of radioresistance and tumor suppression.
Topics: Adenocarcinoma; Apoptosis; Blotting, Western; Cell Cycle; Cell Proliferation; Cytoprotection; Fluorescent Antibody Technique; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Lung Neoplasms; Radiation Tolerance; Radiation, Ionizing; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2011 |
Hsp25 and Hsp70 in rodent tumors treated with doxorubicin and lovastatin.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Doxorubicin; Drug Resistance, Neoplasm; Endothelium, Vascular; Female; Fibrosarcoma; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Lovastatin; Lymphoma, B-Cell; Mammary Neoplasms, Animal; Mice; Mice, Inbred Strains; Molecular Chaperones; Neoplasm Proteins; Rats; Rats, Inbred Strains | 2003 |
Chemotherapy and zoledronate sensitize solid tumour cells to Vgamma9Vdelta2 T cell cytotoxicity.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Burkitt Lymphoma; Carcinoma; Cell Line, Tumor; Cisplatin; Colorectal Neoplasms; Concanavalin A; Cytotoxicity, Immunologic; Diphosphonates; Doxorubicin; Drug Screening Assays, Antitumor; Drug Synergism; Etoposide; Female; Genes, T-Cell Receptor delta; Genes, T-Cell Receptor gamma; Humans; Imidazoles; Interferon-gamma; Lovastatin; Lung Neoplasms; Male; Membrane Glycoproteins; Neoplasms; Perforin; Pore Forming Cytotoxic Proteins; Prostatic Neoplasms; Receptors, Antigen, T-Cell, gamma-delta; T-Lymphocyte Subsets; Urinary Bladder Neoplasms; Vincristine; Zoledronic Acid | 2007 |
Potentiated antitumor effects of the combination treatment with statins and pamidronate in vitro and in vivo.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Cell Adhesion; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Diphosphonates; Drug Synergism; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Lovastatin; Mice; Pamidronate; Pancreatic Neoplasms | 2007 |
Increased basolateral sorting of carcinoembryonic antigen in a polarized colon carcinoma cell line after cholesterol depletion-Implications for treatment of inflammatory bowel disease.
Topics: Adenocarcinoma; Anticholesteremic Agents; beta-Cyclodextrins; Biological Transport; Caco-2 Cells; Carcinoembryonic Antigen; Cell Line, Tumor; Cell Membrane; Cholesterol; Colonic Neoplasms; Humans; Inflammatory Bowel Diseases; Lovastatin | 2008 |
Statins inhibit proliferation and induce apoptosis in Barrett's esophageal adenocarcinoma cells.
Topics: Adenocarcinoma; Analysis of Variance; Animals; Apoptosis; Barrett Esophagus; Caspase 3; Cell Division; Cell Line, Tumor; Dose-Response Relationship, Drug; Esophageal Neoplasms; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoblotting; Lovastatin; Mevalonic Acid; Nitrobenzenes; Polyisoprenyl Phosphates; Pravastatin; Protein Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sesquiterpenes; Signal Transduction; Simvastatin; Sulfonamides | 2008 |
Statins in esophageal cancer cell lines: promising lead?
Topics: Adenocarcinoma; Animals; Apoptosis; Barrett Esophagus; Cell Line, Tumor; Dose-Response Relationship, Drug; Esophageal Neoplasms; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Pravastatin; Simvastatin | 2008 |
Prevention of 1,2-dimethylhydrazine-induced colon tumorigenesis by HMG-CoA reductase inhibitors, pravastatin and simvastatin, in ICR mice.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Anticarcinogenic Agents; Carcinogens; Cholesterol; Colonic Neoplasms; Dimethylhydrazines; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mice; Mice, Inbred ICR; Pravastatin; Simvastatin | 1994 |
Cytotoxicity of simvastatin to pancreatic adenocarcinoma cells containing mutant ras gene.
Topics: Adenocarcinoma; Animals; Base Sequence; Cell Cycle; Codon; Cricetinae; DNA, Neoplasm; Genes, ras; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Molecular Sequence Data; Pancreatic Neoplasms; Point Mutation; Protein Prenylation; Proto-Oncogene Proteins p21(ras); Sensitivity and Specificity; Simvastatin; Tumor Cells, Cultured | 1994 |
Importance of mevalonate-derived products in the control of HMG-CoA reductase activity and growth of human lung adenocarcinoma cell line A549.
Topics: Adenocarcinoma; Cholesterol, LDL; Feedback; Humans; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Lovastatin; Lung Neoplasms; Mevalonic Acid | 1993 |
Lovastatin potentiates the photocytotoxic effect of photofrin II delivered to HT29 human colonic adenocarcinoma cells by low density lipoprotein.
Topics: Adenocarcinoma; Biological Transport; Cell Survival; Colonic Neoplasms; Dihematoporphyrin Ether; Drug Synergism; Humans; Light; Lipoproteins, LDL; Lovastatin; Receptors, LDL; Sterols; Tumor Cells, Cultured | 1993 |
Regulation of cholesterol synthesis in four colonic adenocarcinoma cell lines.
Topics: Adenocarcinoma; Binding, Competitive; Blood; Cholesterol; Cholesterol, LDL; Colonic Neoplasms; Culture Media; Enzyme Inhibitors; Humans; Hydroxycholesterols; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins, LDL; Lovastatin; Receptors, LDL; Tumor Cells, Cultured | 1995 |
Effects of monoterpenes and mevinolin on murine colon tumor CT-26 in vitro and its hepatic "metastases" in vivo.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Colonic Neoplasms; Cyclohexenes; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Limonene; Liver Neoplasms; Lovastatin; Mice; Mice, Inbred BALB C; Monoterpenes; Protein Prenylation; Terpenes; Tumor Cells, Cultured | 1996 |
Enhancement of the herpes simplex virus thymidine kinase/ganciclovir bystander effect and its antitumor efficacy in vivo by pharmacologic manipulation of gap junctions.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Chamomile; Connexin 43; Flavonoids; Ganciclovir; Gap Junctions; Humans; Lovastatin; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Oils, Volatile; Plants, Medicinal; Rats; Simplexvirus; Survival Rate; Thymidine Kinase; Treatment Outcome; Tumor Cells, Cultured | 1998 |
Low density lipoproteins and Lovastatin modulate the organ-specific transendothelial migration of primary and metastatic human colon adenocarcinoma cell lines in vitro.
Topics: Adenocarcinoma; Animals; Cell Adhesion; Cell Movement; Colonic Neoplasms; Endothelium, Vascular; Humans; Lipoproteins, LDL; Liver Neoplasms; Lovastatin; Mice; Mice, Inbred BALB C; Organ Specificity; Time Factors; Tumor Cells, Cultured | 1998 |
Role of RhoA activation in the growth and morphology of a murine prostate tumor cell line.
Topics: Actin Cytoskeleton; Adenocarcinoma; Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Apoptosis; Cell Adhesion; Cell Division; Cell Size; Diterpenes; Drug Interactions; Enzyme Activation; Farnesol; G1 Phase; Genes, ras; GTP-Binding Proteins; Guanosine Triphosphate; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Mevalonic Acid; Mice; Mice, Transgenic; Polyisoprenyl Phosphates; Prostatic Neoplasms; Protein Prenylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins p21(ras); rac GTP-Binding Proteins; rhoA GTP-Binding Protein; Sesquiterpenes; Tumor Cells, Cultured | 1999 |
Activation of the cholesterol pathway and Ras maturation in response to stress.
Topics: Adenocarcinoma; Calcium-Calmodulin-Dependent Protein Kinases; Cholesterol; Diterpenes; Farnesol; Genes, ras; Heat-Shock Response; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent; Lovastatin; Male; Mevalonic Acid; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Prostatic Neoplasms; Protein Prenylation; ras Proteins; Sterols; Stress, Physiological | 1999 |
3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors reduce human pancreatic cancer cell invasion and metastasis.
Topics: Adenocarcinoma; Animals; Cell Division; Cell Membrane; Cytosol; Epidermal Growth Factor; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Liver Neoplasms, Experimental; Lovastatin; Mice; Mice, Nude; Neoplasm Invasiveness; Pancreatic Neoplasms; rhoA GTP-Binding Protein; Tumor Cells, Cultured | 2002 |
Synergism between a novel amphibian oocyte ribonuclease and lovastatin in inducing cytostatic and cytotoxic effects in human lung and pancreatic carcinoma cell lines.
Topics: Adenocarcinoma; Antineoplastic Agents; Cell Division; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Egg Proteins; Humans; Kinetics; Lovastatin; Lung Neoplasms; Mevalonic Acid; Oocytes; Pancreatic Neoplasms; Ribonucleases | 1992 |
Inhibition of protein isoprenylation and p21ras membrane association by dehydroepiandrosterone in human colonic adenocarcinoma cells in vitro.
Topics: Adenocarcinoma; Blotting, Western; Cell Compartmentation; Cell Division; Cell Membrane; Colonic Neoplasms; Dehydroepiandrosterone; Humans; In Vitro Techniques; Lovastatin; Mevalonic Acid; Protein Processing, Post-Translational; Proto-Oncogene Proteins p21(ras); Terpenes; Tumor Cells, Cultured | 1991 |
Effect of lovastatin on acyl-CoA: cholesterol O-acyltransferase (ACAT) activity and the basolateral-membrane secretion of newly synthesized lipids by CaCo-2 cells.
Topics: Adenocarcinoma; Biological Transport; Cell Line; Cell Membrane; Cholesterol; Cholesterol Esters; Colonic Neoplasms; Humans; Hydroxymethylglutaryl CoA Reductases; Kinetics; Lovastatin; Mevalonic Acid; Sterol O-Acyltransferase; Triglycerides | 1990 |