lovastatin has been researched along with Acute Myelogenous Leukemia in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 7 (87.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Jonge-Peeters, SD; de Vries, EG; Kuipers, F; Sluiter, WJ; van der Weide, K; Vellenga, E | 1 |
| Appelbaum, FR; Banker, DE; Li, HY; Mayer, SJ; Willman, CL; Zager, RA | 1 |
| Khosravi, F; Minden, MD; Penn, LZ; Wong, WW; Wu, J | 1 |
| Hohl, RJ; Holstein, SA; Lewis, KA | 1 |
| Burke, LP; Kukoly, CA | 1 |
| Clutterbuck, RD; Millar, JL; Newman, A; Powles, RL | 1 |
| Csipai, M; Glasmacher, A; Huhn, D; Lefterova, P; Neubauer, A; Scheffold, C; Schmidt-Wolf, IG; Schöttker, B | 1 |
| Dimitroulakos, J; Minden, MD; Nohynek, D; Penn, LZ | 1 |
8 other study(ies) available for lovastatin and Acute Myelogenous Leukemia
| Article | Year |
|---|---|
Variability in responsiveness to lovastatin of the primitive CD34+ AML subfraction compared to normal CD34+ cells.
Topics: Adult; Aged; Antigens, CD34; Apoptosis; Cell Separation; Cells, Cultured; Humans; Leukemia, Myeloid, Acute; Lovastatin; Middle Aged; Treatment Outcome | 2009 |
Cholesterol synthesis and import contribute to protective cholesterol increments in acute myeloid leukemia cells.
Topics: Biological Transport; Cholesterol, LDL; Coenzyme A Ligases; Cytarabine; Flow Cytometry; Humans; Hydroxymethylglutaryl-CoA Synthase; Leukemia, Myeloid, Acute; Lovastatin; Receptors, LDL; RNA, Messenger; Tumor Cells, Cultured | 2004 |
Blocking the Raf/MEK/ERK pathway sensitizes acute myelogenous leukemia cells to lovastatin-induced apoptosis.
Topics: Antineoplastic Agents; Apoptosis; Down-Regulation; Flavonoids; Humans; Leukemia, Myeloid, Acute; Lovastatin; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Polyisoprenyl Phosphates; Proto-Oncogene Proteins c-raf | 2004 |
Lovastatin alters the isoprenoid biosynthetic pathway in acute myelogenous leukemia cells in vivo.
Topics: Adult; Aged; Antineoplastic Agents; Cell Proliferation; Cells, Cultured; Female; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukemia, Myeloid, Acute; Lovastatin; Male; Middle Aged; Protein Prenylation; Proto-Oncogene Proteins p21(ras); Signal Transduction; Terpenes | 2005 |
Statins induce lethal effects in acute myeloblastic leukemia [corrected] cells within 72 hours.
Topics: Apoptosis; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukemia, Myeloid, Acute; Lovastatin; Mevalonic Acid | 2008 |
Selective inhibition of primary acute myeloid leukaemia cell growth by lovastatin.
Topics: Adult; Bone Marrow; Bone Marrow Cells; Cell Division; Cell Survival; Cholesterol; Female; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Lovastatin; Male; Middle Aged; Neoplastic Stem Cells; Tumor Cells, Cultured | 1994 |
Increased sensitivity of myeloid leukemia cell lines: potential of lovastatin as bone-marrow-purging agent.
Topics: Bone Marrow Cells; Bone Marrow Purging; Bone Marrow Transplantation; Cell Survival; Clone Cells; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Growth Inhibitors; Hematopoietic Stem Cells; Humans; K562 Cells; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid, Acute; Lovastatin; Monocytes; Transplantation, Autologous | 2000 |
Lovastatin induced control of blast cell growth in an elderly patient with acute myeloblastic leukemia.
Topics: Aged; Anticholesteremic Agents; Antineoplastic Agents; Cell Death; Female; Humans; Leukemia, Myeloid, Acute; Lovastatin | 2001 |