losartan-potassium and Sexual-Dysfunctions--Psychological

The clinical management of gynaecological cancer patients has been mainly focused on prolonging the survival of the patients. Thus, research on MEDLINE using as keywords 'Quality of Life' (QoL) allowed us to identify few papers which reported data on QoL in gynecological oncology. However, the assessment of QoL is becoming one of the most important issues in gynecological oncology, and there is a growing interest in including quality of life measurements in clinical trials. In fact, in several randomised trials on ovarian cancer now ongoing in Europe, the evaluation of QoL has been planned. The one underlying this article focuses on the symptoms and problems particular to gynecologic cancer and the treatments of them that could affect quality of life evaluations. These include limitations of sexual activity and fertility, early menopause, chemotherapy induced toxicity, and loss of body image. In this report, we will discuss the aspects affecting the QoL in gynaecological cancer in relation to surgical treatment, medical therapy, and follow-up.

Topics: Anemia; Clinical Trials as Topic; Erythropoietin; Female; Follow-Up Studies; Genetic Counseling; Genital Neoplasms, Female; Humans; Outcome Assessment, Health Care; Postoperative Complications; Quality of Life; Sexual Dysfunctions, Psychological

For patients with end-stage renal disease (ESRD) whose anemia is corrected with Epoetin alfa, a higher hematocrit typically results in increased well-being and renewed interest in life, including sexual activity. Paradoxically, this generally positive therapeutic outcome can result in sexual problems for the patient and his or her partner because of changing expectations. Understanding the physical and psychosocial causes of sexual dysfunction in patients with ESRD, as well as strategies for assessment and intervention, prepares nurses to anticipate sexual problems and intervene appropriately.

Topics: Adult; Erythropoietin; Humans; Kidney Failure, Chronic; Male; Sexual Dysfunctions, Psychological