losartan-potassium has been researched along with Giant-Cell-Tumor-of-Bone* in 2 studies
2 other study(ies) available for losartan-potassium and Giant-Cell-Tumor-of-Bone
| Article | Year |
|---|---|
Role of autologous blood transfusion in sacral tumor resection: patient selection and recovery after surgery and blood donation.
We carried out sacral en-bloc resection in six patients (three with chordoma; one with pheochromocytoma; one with malignant schwannoma; and one with giant cell tumor) using preoperatively collected autologous blood, to avoid homologous blood transfusion. An average of 3200 ml was collected preoperatively, with patients receiving recombinant human erythropoietin (r-HuEPO), at a total dose of 130 000 units on average. In four patients, we were able to accomplish the surgery without homologous blood transfusion. Postoperatively, the hemoglobin level in these four patients recovered to the pre-collective level in 4.5 weeks, on average. These clinical results indicate that en-bloc sacrectomy, which requires a large volume of blood transfusion, can be accomplished with preoperatively collected autologous blood alone. Topics: Adrenal Gland Neoplasms; Aged; Blood Donors; Blood Loss, Surgical; Blood Transfusion, Autologous; Chordoma; Erythropoietin; Female; Giant Cell Tumor of Bone; Hemoglobinometry; Humans; Hypotension, Controlled; Male; Middle Aged; Neurilemmoma; Pheochromocytoma; Recombinant Proteins; Sacrum; Spinal Neoplasms | 2000 |
Use of preoperative autologous blood donations and erythropoietin for treatment of giant cell tumor of the ischium.
A 24-year-old man with an osteolytic lesion of the ischium was referred to the authors' institution. Computed tomography and magnetic resonance imaging studies showed that the lesion extended to and involved the subchondral bone of the acetabulum. Histologic examination of the biopsy specimen revealed giant cell tumor of bone. Following the biopsy, autologous blood was collected 4 times with recombinant human erythropoietin treatment definitive surgery was performed. Three weeks after the biopsy, the lesion was curetted and bone cementation was performed. The total blood loss during surgery was 3100 ml, which was replaced successfully with stored autologous blood without the need for homologous blood transfusion. The authors believe that without the erythropoietin treatment, autologous blood could have been collected only 3 times instead of 4 times, and the patient would have needed homologous blood. Topics: Adult; Blood Loss, Surgical; Blood Transfusion, Autologous; Bone Neoplasms; Erythropoietin; Giant Cell Tumor of Bone; Humans; Ischium; Male; Preoperative Care; Recombinant Proteins | 1996 |