losartan-potassium and Eclampsia

The estimation of cord blood erythropoietin in subjects with pre-eclampsia and eclampsia.. Erythropoietin was measured, using ELISA, in the cord blood of infants born to 83 mothers with pre-eclampsia, and 7 with eclampsia. Another 90 subjects with no evidence of pre-eclampsia or eclampsia were taken as control subjects. Maternal parity, gestational age, blood pressures, 24-h urine protein and Apgar scores of the infants delivered were also noted.. Cord blood erythropoietin levels were statistically significantly higher (P<0.001) in infants born to mothers with pre-eclampsia and eclampsia. There was a significant positive correlation (P<0.01) between cord blood erythropoietin levels and maternal blood pressure (systolic and diastolic) and albuminuria. A negative correlation (P<0.01) was observed with the birth weights of infants.. Pre-eclampsia and eclampsia are associated with higher levels of cord blood erythropoietin.

Topics: Adult; Albuminuria; Apgar Score; Biomarkers; Birth Weight; Blood Pressure; Case-Control Studies; Eclampsia; Enzyme-Linked Immunosorbent Assay; Erythropoietin; Female; Fetal Blood; Gravidity; Humans; Hydrogen-Ion Concentration; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Uric Acid

Topics: Adult; Eclampsia; Erythroblastosis, Fetal; Erythropoietin; Female; Fetal Diseases; Humans; Hypoxia; Infant, Newborn; Infant, Premature; Iron Isotopes; Pregnancy; Pregnancy in Diabetics; Umbilical Cord