Page last updated: 2024-10-30

losartan and Weight Gain

losartan has been researched along with Weight Gain in 11 studies

Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position

Weight Gain: Increase in BODY WEIGHT over existing weight.

Research Excerpts

ExcerptRelevanceReference
" The AT(1) receptor for angiotensin II (Ang II) is involved in the renal expression of the nuclear factor-kappa B (NF-ΚB) during this nephrosis."7.77Proinflammatory role of angiotensin II in a rat nephrosis model induced by adriamycin. ( Hernández-Fonseca, JP; Mosquera, J; Muñoz, M; Pedreañez, A; Rincón, J; Viera, N, 2011)
"To study the effect of losartan, an angiotensin II antagonist, on bleomycin-induced pulmonary fibrosis in rats and its possible mechanism."7.73Losartan attenuates bleomycin-induced pulmonary fibrosis in rats. ( Lu, Y; Yao, HW; Zhao, MH; Zhu, JP, 2006)
" The AT(1) receptor for angiotensin II (Ang II) is involved in the renal expression of the nuclear factor-kappa B (NF-ΚB) during this nephrosis."3.77Proinflammatory role of angiotensin II in a rat nephrosis model induced by adriamycin. ( Hernández-Fonseca, JP; Mosquera, J; Muñoz, M; Pedreañez, A; Rincón, J; Viera, N, 2011)
"To study the effect of losartan, an angiotensin II antagonist, on bleomycin-induced pulmonary fibrosis in rats and its possible mechanism."3.73Losartan attenuates bleomycin-induced pulmonary fibrosis in rats. ( Lu, Y; Yao, HW; Zhao, MH; Zhu, JP, 2006)
"Telmisartan is an angiotensin II receptor blocker and selective modulator of peroxisome proliferator-activated receptor-gamma reported to increase energy expenditure and improve glucose and lipid metabolism compared with other angiotensin II receptor blockers."1.35Telmisartan increases fatty acid oxidation in skeletal muscle through a peroxisome proliferator-activated receptor-gamma dependent pathway. ( Hyakukoku, M; Kazdová, L; Kren, V; Kurtz, TW; Pravenec, M; Qi, NR; Simáková, M; Sugimoto, K; Zídek, V, 2008)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (18.18)18.2507
2000's4 (36.36)29.6817
2010's3 (27.27)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
do Carmo, JM1
Dai, X1
Aitken, N1
Larson, KM1
Omoto, ACM1
Gulke, RR1
Wang, Z1
Li, X1
Mouton, AJ1
Hall, JE1
da Silva, AA1
Karimi, J1
Mohammadalipour, A1
Sheikh, N1
Khodadadi, I1
Hashemnia, M1
Goudarzi, F1
Khanjarsim, V1
Solgi, G1
Hajilooi, M1
Bahabadi, M1
Kheiripour, N1
Hedayatyanfard, K1
Muñoz, M1
Rincón, J1
Pedreañez, A1
Viera, N1
Hernández-Fonseca, JP1
Mosquera, J1
Gupte, M1
Thatcher, SE1
Boustany-Kari, CM1
Shoemaker, R1
Yiannikouris, F1
Zhang, X1
Karounos, M1
Cassis, LA1
Ashrafi, F1
Nematbakhsh, M1
Safari, T1
Talebi, A1
Nasri, H1
Khazaei, M1
Baradaran-Mahdavi, MM1
Jafapisheh, A1
Olia, B1
Pirhaji, O1
Hashemi-Nia, SJ1
Eshraghi, F1
Pezeshki, Z1
Mortazavi, M1
Benson, SC1
Pershadsingh, HA1
Ho, CI1
Chittiboyina, A1
Desai, P1
Pravenec, M2
Qi, N1
Wang, J1
Avery, MA1
Kurtz, TW2
Yao, HW1
Zhu, JP1
Zhao, MH1
Lu, Y1
Sugimoto, K1
Kazdová, L1
Qi, NR1
Hyakukoku, M1
Kren, V1
Simáková, M1
Zídek, V1
Zanchi, A1
Schaad, NC1
Osterheld, MC1
Grouzmann, E1
Nussberger, J1
Brunner, HR1
Waeber, B1
Schneider, AW1
Kalk, JF1
Klein, CP1
Shimada, N1
Hayashi, K1
Saka, S1
Nakamura, T1
Ebihara, I1
Koide, H1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized, Placebo Controlled, Double Blind Trial of Telmisartan in Hypertensive, Obese Adolescents[NCT00185705]30 participants (Anticipated)Interventional2006-10-31Terminated (stopped due to Primary investigator moved to different university)
Molecular - Genetic Alterations in Adipose Tissue After Change in Therapy From ACE Inhibitors to AT1 Receptor Blockers in Patients With Essential Hypertension[NCT01444833]35 participants (Anticipated)Interventional2008-10-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for losartan and Weight Gain

ArticleYear
Effect of losartan, an angiotensin II receptor antagonist, on portal pressure in cirrhosis.
    Hepatology (Baltimore, Md.), 1999, Volume: 29, Issue:2

    Topics: Adult; Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Bilirubin; Female; Hemodynam

1999

Other Studies

10 other studies available for losartan and Weight Gain

ArticleYear
Sex differences in weight gain, blood pressure control, and responses to melanocortin-4 receptor antagonism in offspring from lean and obese parents.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2023, 10-01, Volume: 325, Issue:4

    Topics: Adrenergic Agents; Adult; Blood Pressure; Female; Humans; Hypertension; Losartan; Male; Obesity; Rec

2023
Protective effects of combined Losartan and Nilotinib on carbon tetrachloride (CCl
    Drug and chemical toxicology, 2020, Volume: 43, Issue:5

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Carbon Tetrachloride; Drug Therapy, Combination; L

2020
Proinflammatory role of angiotensin II in a rat nephrosis model induced by adriamycin.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2011, Volume: 12, Issue:4

    Topics: Angiotensin II; Animals; Cholesterol; Disease Models, Animal; Doxorubicin; Endothelin-1; Fluorescent

2011
Angiotensin converting enzyme 2 contributes to sex differences in the development of obesity hypertension in C57BL/6 mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2012, Volume: 32, Issue:6

    Topics: 3T3-L1 Cells; Adipocytes; Adiposity; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor B

2012
A combination of vitamin C and losartan for cisplatin-induced nephrotoxicity in rats.
    Iranian journal of kidney diseases, 2012, Volume: 6, Issue:5

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Ascorbic Acid; Biomarkers; Blood Pro

2012
Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activity.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:5

    Topics: Adipocytes; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Biphenyl Co

2004
Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activity.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:5

    Topics: Adipocytes; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Biphenyl Co

2004
Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activity.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:5

    Topics: Adipocytes; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Biphenyl Co

2004
Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activity.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:5

    Topics: Adipocytes; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Biphenyl Co

2004
Losartan attenuates bleomycin-induced pulmonary fibrosis in rats.
    Respiration; international review of thoracic diseases, 2006, Volume: 73, Issue:2

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antibiotics, Antineoplastic; Bleomycin; Body Weigh

2006
Telmisartan increases fatty acid oxidation in skeletal muscle through a peroxisome proliferator-activated receptor-gamma dependent pathway.
    Journal of hypertension, 2008, Volume: 26, Issue:6

    Topics: Adiposity; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Fatty Acids;

2008
Effects of chronic NO synthase inhibition in rats on renin-angiotensin system and sympathetic nervous system.
    The American journal of physiology, 1995, Volume: 268, Issue:6 Pt 2

    Topics: Amino Acid Oxidoreductases; Analysis of Variance; Animals; Antihypertensive Agents; Arginine; Biphen

1995
Does angiotensin II receptor antagonist Losartan suppress drinking behavior in hemodialysis patients?
    Renal failure, 2001, Volume: 23, Issue:5

    Topics: Aged; Drinking Behavior; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Kidney Fai

2001