losartan has been researched along with Venous Thrombosis in 7 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
Venous Thrombosis: The formation or presence of a blood clot (THROMBUS) within a vein.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The potential antithrombotic action of losartan, the AT1 receptor antagonist, in an experimental model of venous thrombosis in spontaneously hypertensive rats (SHR) and Wistar Kyoto rats (WKY) was tested." | 7.70 | Losartan inhibits experimental venous thrombosis in spontaneously hypertensive rats. ( Buczko, W; Chabielska, E; Golatowski, J; Pawlak, D; Pawlak, R; Rółkowski, R, 1998) |
| "The potential antithrombotic action of losartan, the AT1 receptor antagonist, in an experimental model of venous thrombosis in spontaneously hypertensive rats (SHR) and Wistar Kyoto rats (WKY) was tested." | 3.70 | Losartan inhibits experimental venous thrombosis in spontaneously hypertensive rats. ( Buczko, W; Chabielska, E; Golatowski, J; Pawlak, D; Pawlak, R; Rółkowski, R, 1998) |
| "The potential antithrombotic action of losartan, an AT1 receptor antagonist, administered to two-kidney, one-clip rats (2K1C) in an experimental model of venous thrombosis was evaluated." | 3.70 | Antithrombotic activity of losartan in two kidney, one clip hypertensive rats. A study on the mechanism of action. ( Buczko, W; Chabielska, E; Pawlak, R; Rółkowski, R; Wollny, T, 1999) |
| "Stasis-induced venous thrombus was allowed to age for 7 hours before intravenous injection of EXP3174 (10 mg/kg and 30 mg/kg)." | 1.51 | Losartan metabolite EXP3174 reduces the weight of formed thrombus in 2K1C hypertensive rats. ( Chabielska, E; Gromotowicz-Poplawska, A; Nazarko-Sadowska, J, 2019) |
| "Venous thrombosis was induced by ligation of vena cava." | 1.33 | Angiotensin II enhances thrombosis development in renovascular hypertensive rats. ( Buczko, W; Chabielska, E; Mogielnicki, A; Pawlak, R; Szemraj, J, 2005) |
| " Acute losartan dosing to 2K-1C rats decreased platelet adhesion to fibrillar collagen(24." | 1.31 | The antithrombotic effect of angiotensin-(1-7) closely resembles that of losartan. ( Buczko, W; Chabielska, E; Kucharewicz, I; Matys, T; Pawlak, D; Rólkowski, R, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gromotowicz-Poplawska, A | 1 |
| Nazarko-Sadowska, J | 1 |
| Chabielska, E | 6 |
| Kucharewicz, I | 3 |
| Pawlak, R | 4 |
| Matys, T | 3 |
| Pawlak, D | 4 |
| Buczko, W | 6 |
| Mogielnicki, A | 1 |
| Szemraj, J | 1 |
| Golatowski, J | 1 |
| Rółkowski, R | 2 |
| Wollny, T | 1 |
| Rólkowski, R | 2 |
7 other studies available for losartan and Venous Thrombosis
| Article | Year |
|---|---|
Losartan metabolite EXP3174 reduces the weight of formed thrombus in 2K1C hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Coagulation; Blood Platelets; Blood Pressure; Hemostasis; Hy | 2019 |
Antithrombotic effect of captopril and losartan is mediated by angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhib | 2002 |
Angiotensin II enhances thrombosis development in renovascular hypertensive rats.
Topics: alpha-2-Antiplasmin; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin III; Anima | 2005 |
Losartan inhibits experimental venous thrombosis in spontaneously hypertensive rats.
Topics: Analysis of Variance; Animals; Antihypertensive Agents; Blood Pressure; Hemostasis; Losartan; Male; | 1998 |
Antithrombotic activity of losartan in two kidney, one clip hypertensive rats. A study on the mechanism of action.
Topics: Angiotensin Receptor Antagonists; Animals; Blood Platelets; Disease Models, Animal; Fibrinolytic Age | 1999 |
The involvement of AT(2)-receptor in the antithrombotic effect of losartan in renal hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Fibrinolytic Agents; Hypertension, Renovascular; I | 2000 |
The antithrombotic effect of angiotensin-(1-7) closely resembles that of losartan.
Topics: Angiotensin I; Animals; Antihypertensive Agents; Blood Pressure; Collagen; Fibrinolytic Agents; Hemo | 2000 |