losartan has been researched along with Vasospasm, Intracranial in 4 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
Vasospasm, Intracranial: Constriction of arteries in the SKULL due to sudden, sharp, and often persistent smooth muscle contraction in blood vessels. Intracranial vasospasm results in reduced vessel lumen caliber, restricted blood flow to the brain, and BRAIN ISCHEMIA that may lead to hypoxic-ischemic brain injury (HYPOXIA-ISCHEMIA, BRAIN).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cerebral vasospasm was induced by the use of an established double-injection rat model." | 1.56 | The Role of Losartan as a Potential Neuroregenerative Pharmacological Agent after Aneurysmal Subarachnoid Haemorrhage. ( Andereggen, L; Kashefiolasl, S; Konczalla, J; Marbacher, S; Mrosek, J; Wanderer, S, 2020) |
| "Losartan has a dose-dependent antagonistic effect to the ET-1 induced contraction, which seems to ET(B)-receptor dependent." | 1.39 | Crosstalk between the angiotensin and endothelin-system in the cerebrovasculature. ( Güresir, E; Konczalla, J; Mrosek, J; Platz, J; Schuss, P; Seifert, V; Vatter, H; Wanderer, S, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wanderer, S | 3 |
| Andereggen, L | 1 |
| Mrosek, J | 3 |
| Kashefiolasl, S | 1 |
| Marbacher, S | 1 |
| Konczalla, J | 3 |
| Vatter, H | 2 |
| Seifert, V | 2 |
| Schuss, P | 1 |
| Platz, J | 1 |
| Güresir, E | 1 |
| Fassot, C | 1 |
| Lambert, G | 1 |
| Gaudet-Lambert, E | 1 |
| Friberg, P | 1 |
| Elghozi, JL | 1 |
4 other studies available for losartan and Vasospasm, Intracranial
| Article | Year |
|---|---|
The Role of Losartan as a Potential Neuroregenerative Pharmacological Agent after Aneurysmal Subarachnoid Haemorrhage.
Topics: Animals; Basilar Artery; Disease Models, Animal; Endothelin-1; Losartan; Male; NG-Nitroarginine Meth | 2020 |
Crosstalk between the angiotensin and endothelin system in the cerebrovasculature after experimental induced subarachnoid hemorrhage.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensins; Animals; Basilar Artery; Disease Models, Anim | 2018 |
Crosstalk between the angiotensin and endothelin-system in the cerebrovasculature.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensins; Animals; Basilar Artery; Cell Communication; | 2013 |
Beneficial effect of renin-angiotensin system for maintaining blood pressure control following subarachnoid haemorrhage.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Blood Transfusion, Autologous; Brain Ischemia; Los | 1999 |