losartan has been researched along with Status Epilepticus in 5 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
Status Epilepticus: A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes. The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction. Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances. Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition (see also EPILEPSIA PARTIALIS CONTINUA). Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity. (From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30)
Excerpt | Relevance | Reference |
---|---|---|
"Spontaneous seizures were video- and EEG-monitored in spontaneously hypertensive rats (SHRs) for a 16-week period after SE." | 5.43 | Long-Term Treatment with Losartan Attenuates Seizure Activity and Neuronal Damage Without Affecting Behavioral Changes in a Model of Co-morbid Hypertension and Epilepsy. ( Atanasova, D; Ivanova, N; Kortenska, L; Lazarov, N; Lozanov, V; Mitreva, R; Pechlivanova, DM; Stoynev, A; Tchekalarova, JD, 2016) |
"Spontaneous seizures were video- and EEG-monitored in spontaneously hypertensive rats (SHRs) for a 16-week period after SE." | 1.43 | Long-Term Treatment with Losartan Attenuates Seizure Activity and Neuronal Damage Without Affecting Behavioral Changes in a Model of Co-morbid Hypertension and Epilepsy. ( Atanasova, D; Ivanova, N; Kortenska, L; Lazarov, N; Lozanov, V; Mitreva, R; Pechlivanova, DM; Stoynev, A; Tchekalarova, JD, 2016) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 5 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Bar-Klein, G | 1 |
Lublinsky, S | 1 |
Kamintsky, L | 1 |
Noyman, I | 1 |
Veksler, R | 1 |
Dalipaj, H | 1 |
Senatorov, VV | 1 |
Swissa, E | 1 |
Rosenbach, D | 1 |
Elazary, N | 1 |
Milikovsky, DZ | 1 |
Milk, N | 1 |
Kassirer, M | 1 |
Rosman, Y | 1 |
Serlin, Y | 1 |
Eisenkraft, A | 1 |
Chassidim, Y | 1 |
Parmet, Y | 1 |
Kaufer, D | 1 |
Friedman, A | 1 |
Hong, S | 1 |
JianCheng, H | 1 |
JiaWen, W | 1 |
ShuQin, Z | 1 |
GuiLian, Z | 1 |
HaiQin, W | 1 |
Ru, Z | 1 |
Zhen, G | 1 |
HongWei, R | 1 |
Sun, H | 1 |
Wu, H | 1 |
Yu, X | 1 |
Zhang, G | 1 |
Zhang, R | 1 |
Zhan, S | 1 |
Wang, H | 1 |
Bu, N | 1 |
Ma, X | 1 |
Li, Y | 1 |
Tchekalarova, JD | 1 |
Ivanova, N | 1 |
Atanasova, D | 1 |
Pechlivanova, DM | 1 |
Lazarov, N | 1 |
Kortenska, L | 1 |
Mitreva, R | 1 |
Lozanov, V | 1 |
Stoynev, A | 1 |
Tsai, CY | 1 |
Chan, JY | 1 |
Hsu, KS | 1 |
Chang, AY | 1 |
Chan, SH | 1 |
5 other studies available for losartan and Status Epilepticus
Article | Year |
---|---|
Imaging blood-brain barrier dysfunction as a biomarker for epileptogenesis.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Angiotensin II Type 1 Receptor Blockers; Animals; B | 2017 |
Losartan inhibits development of spontaneous recurrent seizures by preventing astrocyte activation and attenuating blood-brain barrier permeability following pilocarpine-induced status epilepticus.
Topics: Animals; Astrocytes; Blood-Brain Barrier; Brain; Disease Models, Animal; Epilepsy; Losartan; Male; N | 2019 |
Angiotensin II and its receptor in activated microglia enhanced neuronal loss and cognitive impairment following pilocarpine-induced status epilepticus.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cognition Disorders; Hippocampus; | 2015 |
Long-Term Treatment with Losartan Attenuates Seizure Activity and Neuronal Damage Without Affecting Behavioral Changes in a Model of Co-morbid Hypertension and Epilepsy.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Hippocampus; Hypertension; Losartan; Male; Neuron | 2016 |
Brain-derived neurotrophic factor ameliorates brain stem cardiovascular dysregulation during experimental temporal lobe status epilepticus.
Topics: Acetophenones; Animals; Antioxidants; Brain Stem; Brain-Derived Neurotrophic Factor; Cardiovascular | 2012 |