losartan has been researched along with Pulmonary Arterial Remodeling in 11 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
| Excerpt | Relevance | Reference |
|---|---|---|
| "Stroke-prone spontaneously hypertensive (SHRSP) rats were administered losartan, amlodipine or saline for 6 or 16weeks at the onset of prehypertension." | 7.85 | Early treatment with losartan effectively ameliorates hypertension and improves vascular remodeling and function in a prehypertensive rat model. ( He, DH; Lin, JX; Xie, Q; Xu, CS; Zhang, LM, 2017) |
| "Stroke-prone spontaneously hypertensive (SHRSP) rats were administered losartan, amlodipine or saline for 6 or 16weeks at the onset of prehypertension." | 3.85 | Early treatment with losartan effectively ameliorates hypertension and improves vascular remodeling and function in a prehypertensive rat model. ( He, DH; Lin, JX; Xie, Q; Xu, CS; Zhang, LM, 2017) |
| " This study aimed to evaluate the effects of long-term administration of losartan, aspirin, and atorvastatin on vascular remodeling in juvenile spontaneously hypertensive rats (SHRs)." | 1.91 | Effects of Long-Term Intervention with Losartan, Aspirin and Atorvastatin on Vascular Remodeling in Juvenile Spontaneously Hypertensive Rats. ( Dong, B; Dong, S; Li, L; Liu, Q; Shen, J; Yang, K; Zhao, Y; Zhou, X; Zhu, D, 2023) |
| "Aldosterone effects were prevented by the AGTR1 antagonist losartan in WT mice." | 1.43 | Aldosterone-Induced Vascular Remodeling and Endothelial Dysfunction Require Functional Angiotensin Type 1a Receptors. ( Barhoumi, T; Briet, M; Coelho, SC; Coffman, TM; Mian, MOR; Ouerd, S; Paradis, P; Rautureau, Y; Schiffrin, EL, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (72.73) | 24.3611 |
| 2020's | 3 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| França-Neto, A | 1 |
| Couto, GK | 2 |
| Xavier, FE | 1 |
| Rossoni, LV | 2 |
| Liu, Q | 1 |
| Dong, S | 1 |
| Zhou, X | 1 |
| Zhao, Y | 1 |
| Dong, B | 1 |
| Shen, J | 1 |
| Yang, K | 1 |
| Li, L | 1 |
| Zhu, D | 1 |
| Ge, L | 1 |
| Zhang, G | 1 |
| You, B | 1 |
| Cheng, G | 1 |
| Chen, L | 1 |
| Shi, R | 1 |
| Tong, Y | 1 |
| Ye, C | 1 |
| Ren, XS | 1 |
| Qiu, Y | 1 |
| Zang, YH | 1 |
| Xiong, XQ | 1 |
| Wang, JJ | 1 |
| Chen, Q | 1 |
| Li, YH | 1 |
| Kang, YM | 1 |
| Zhu, GQ | 1 |
| Zhou, Z | 1 |
| Peters, AM | 1 |
| Wang, S | 1 |
| Janda, A | 1 |
| Chen, J | 1 |
| Zhou, P | 1 |
| Arthur, E | 1 |
| Kwartler, CS | 1 |
| Milewicz, DM | 1 |
| Dubacher, N | 1 |
| Münger, J | 1 |
| Gorosabel, MC | 1 |
| Crabb, J | 1 |
| Ksiazek, AA | 1 |
| Caspar, SM | 1 |
| Bakker, ENTP | 1 |
| van Bavel, E | 1 |
| Ziegler, U | 1 |
| Carrel, T | 1 |
| Steinmann, B | 1 |
| Zeisberger, S | 1 |
| Meienberg, J | 1 |
| Matyas, G | 1 |
| Li, LD | 1 |
| Tian, M | 1 |
| Liao, YH | 1 |
| Zhou, ZH | 1 |
| Wei, F | 1 |
| Zhu, F | 1 |
| Wang, M | 1 |
| Wang, B | 1 |
| Wei, YM | 1 |
| Sun, F | 1 |
| Song, Y | 1 |
| Liu, J | 1 |
| Ma, LJ | 1 |
| Shen, Y | 1 |
| Huang, J | 1 |
| Zhou, YL | 1 |
| Casare, FA | 1 |
| Thieme, K | 1 |
| Costa-Pessoa, JM | 1 |
| Fernandes, FB | 1 |
| Casarini, DE | 1 |
| Oliveira-Souza, M | 1 |
| Briet, M | 1 |
| Barhoumi, T | 1 |
| Mian, MOR | 1 |
| Coelho, SC | 1 |
| Ouerd, S | 1 |
| Rautureau, Y | 1 |
| Coffman, TM | 1 |
| Paradis, P | 1 |
| Schiffrin, EL | 1 |
| He, DH | 1 |
| Lin, JX | 1 |
| Zhang, LM | 1 |
| Xu, CS | 1 |
| Xie, Q | 1 |
11 other studies available for losartan and Pulmonary Arterial Remodeling
| Article | Year |
|---|---|
Cyclooxygenase-2 is a critical determinant of angiotensin II-induced vascular remodeling and stiffness in resistance arteries of ouabain-treated rats.
Topics: Angiotensin II; Animals; bcl-2-Associated X Protein; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; | 2022 |
Effects of Long-Term Intervention with Losartan, Aspirin and Atorvastatin on Vascular Remodeling in Juvenile Spontaneously Hypertensive Rats.
Topics: Animals; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressure; Collagen; Hypertension; Int | 2023 |
The role of losartan in preventing vascular remodeling in spontaneously hypertensive rats by inhibition of the H
Topics: Animals; Antihypertensive Agents; Dose-Response Relationship, Drug; Female; Hydrogen Peroxide; Hyper | 2017 |
Exosome-Mediated Transfer of ACE (Angiotensin-Converting Enzyme) From Adventitial Fibroblasts of Spontaneously Hypertensive Rats Promotes Vascular Smooth Muscle Cell Migration.
Topics: Adventitia; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Aniline Comp | 2018 |
Reversal of Aortic Enlargement Induced by Increased Biomechanical Forces Requires AT1R Inhibition in Conjunction With AT2R Activation.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Aorta; Ao | 2019 |
Celiprolol but not losartan improves the biomechanical integrity of the aorta in a mouse model of vascular Ehlers-Danlos syndrome.
Topics: Adrenergic beta-1 Receptor Antagonists; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Tho | 2020 |
Effect of active immunization against angiotensin II type 1 (AT1) receptor on hypertension & arterial remodelling in spontaneously hypertensive rats (SHR).
Topics: Analysis of Variance; Animals; Antibodies; Blood Pressure Determination; Enzyme-Linked Immunosorbent | 2014 |
Efficacy of losartan for improving insulin resistance and vascular remodeling in hemodialysis patients.
Topics: Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Carotid Arteries; Female; Humans; In | 2016 |
Renovascular remodeling and renal injury after extended angiotensin II infusion.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Glomerular Filtrat | 2016 |
Aldosterone-Induced Vascular Remodeling and Endothelial Dysfunction Require Functional Angiotensin Type 1a Receptors.
Topics: Aldosterone; Analysis of Variance; Animals; Disease Models, Animal; Endothelium, Vascular; Hypertens | 2016 |
Early treatment with losartan effectively ameliorates hypertension and improves vascular remodeling and function in a prehypertensive rat model.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Gene Expression Regula | 2017 |