losartan has been researched along with Pregnancy in 104 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 19 (18.27) | 18.2507 |
2000's | 48 (46.15) | 29.6817 |
2010's | 29 (27.88) | 24.3611 |
2020's | 8 (7.69) | 2.80 |
Authors | Studies |
---|---|
Zoet, GA | 1 |
Paauw, ND | 1 |
Veerbeek, JHW | 1 |
Groenhof, TKJ | 1 |
Spiering, W | 1 |
Verhaar, MC | 1 |
Franx, A | 1 |
Titia Lely, A | 1 |
Abuiessa, SA | 1 |
Helmy, MM | 1 |
El-Gowelli, HM | 1 |
El-Gowilly, SM | 1 |
El-Mas, MM | 1 |
Macchi, R | 1 |
Sotelo, AD | 1 |
Parrado, AC | 1 |
Salaverry, LS | 1 |
Blanco, GA | 1 |
Castro, MS | 1 |
Rey-Roldán, EB | 1 |
Canellada, AM | 1 |
Bo, L | 1 |
Wei, L | 1 |
Shi, L | 4 |
Luo, C | 1 |
Gao, S | 1 |
Zhou, A | 2 |
Mao, C | 5 |
Zhang, M | 2 |
Lu, L | 1 |
Zhang, Y | 7 |
Li, X | 5 |
Fan, X | 1 |
Chen, X | 3 |
Tang, J | 2 |
Han, B | 1 |
Li, M | 1 |
Tao, J | 2 |
Gao, Q | 3 |
Xu, Z | 8 |
Sun, M | 2 |
Warrington, JP | 1 |
Fan, F | 1 |
Duncan, J | 1 |
Cunningham, MW | 2 |
LaMarca, BB | 2 |
Dechend, R | 5 |
Wallukat, G | 5 |
Roman, RJ | 1 |
Drummond, HA | 1 |
Granger, JP | 3 |
Ryan, MJ | 1 |
Nese, M | 1 |
Riboli, G | 1 |
Brighetti, G | 1 |
Sassi, V | 1 |
Camela, E | 1 |
Caselli, G | 1 |
Sassaroli, S | 1 |
Borlimi, R | 1 |
Aucoin, M | 1 |
Cooley, K | 1 |
Saunders, PR | 1 |
Carè, J | 1 |
Anheyer, D | 1 |
Medina, DN | 1 |
Cardozo, V | 1 |
Remy, D | 1 |
Hannan, N | 1 |
Garber, A | 1 |
Velayos, M | 1 |
Muñoz-Serrano, AJ | 1 |
Estefanía-Fernández, K | 1 |
Sarmiento Caldas, MC | 1 |
Moratilla Lapeña, L | 1 |
López-Santamaría, M | 1 |
López-Gutiérrez, JC | 1 |
Li, J | 2 |
Zhang, J | 1 |
Shen, S | 1 |
Zhang, B | 2 |
Yu, WW | 1 |
Toyoda, H | 1 |
Huang, DQ | 1 |
Le, MH | 1 |
Nguyen, MH | 1 |
Huang, R | 1 |
Zhu, L | 1 |
Wang, J | 7 |
Xue, L | 1 |
Liu, L | 2 |
Yan, X | 2 |
Huang, S | 1 |
Li, Y | 6 |
Xu, T | 1 |
Li, C | 2 |
Ji, F | 1 |
Ming, F | 1 |
Zhao, Y | 2 |
Cheng, J | 1 |
Wang, Y | 3 |
Zhao, H | 1 |
Hong, S | 1 |
Chen, K | 2 |
Zhao, XA | 1 |
Zou, L | 1 |
Sang, D | 1 |
Shao, H | 1 |
Guan, X | 1 |
Chen, Y | 4 |
Wei, J | 1 |
Zhu, C | 1 |
Wu, C | 2 |
Moore, HB | 1 |
Barrett, CD | 1 |
Moore, EE | 1 |
Jhunjhunwala, R | 1 |
McIntyre, RC | 1 |
Moore, PK | 1 |
Hajizadeh, N | 1 |
Talmor, DS | 1 |
Sauaia, A | 1 |
Yaffe, MB | 1 |
Liu, C | 3 |
Lin, Y | 1 |
Dong, Y | 1 |
Wu, Y | 1 |
Bao, Y | 1 |
Yan, H | 2 |
Ma, J | 1 |
Fernández-Cuadros, ME | 1 |
Albaladejo-Florín, MJ | 1 |
Álava-Rabasa, S | 1 |
Usandizaga-Elio, I | 1 |
Martinez-Quintanilla Jimenez, D | 1 |
Peña-Lora, D | 1 |
Neira-Borrajo, I | 1 |
López-Muñoz, MJ | 1 |
Rodríguez-de-Cía, J | 1 |
Pérez-Moro, OS | 1 |
Abdallah, M | 1 |
Alsaleh, H | 1 |
Baradwan, A | 1 |
Alfawares, R | 1 |
Alobaid, A | 1 |
Rasheed, A | 1 |
Soliman, I | 1 |
Wendel Garcia, PD | 1 |
Fumeaux, T | 1 |
Guerci, P | 1 |
Heuberger, DM | 1 |
Montomoli, J | 2 |
Roche-Campo, F | 1 |
Schuepbach, RA | 1 |
Hilty, MP | 1 |
Poloni, TE | 1 |
Carlos, AF | 1 |
Cairati, M | 1 |
Cutaia, C | 1 |
Medici, V | 1 |
Marelli, E | 1 |
Ferrari, D | 1 |
Galli, A | 1 |
Bognetti, P | 1 |
Davin, A | 1 |
Cirrincione, A | 1 |
Ceretti, A | 1 |
Cereda, C | 1 |
Ceroni, M | 1 |
Tronconi, L | 1 |
Vitali, S | 1 |
Guaita, A | 1 |
Leeds, JS | 1 |
Raviprakash, V | 1 |
Jacques, T | 1 |
Scanlon, N | 1 |
Cundall, J | 1 |
Leeds, CM | 1 |
Riva, A | 1 |
Gray, EH | 1 |
Azarian, S | 1 |
Zamalloa, A | 1 |
McPhail, MJW | 1 |
Vincent, RP | 1 |
Williams, R | 1 |
Chokshi, S | 1 |
Patel, VC | 1 |
Edwards, LA | 1 |
Alqarawi, W | 1 |
Birnie, DH | 1 |
Golian, M | 1 |
Nair, GM | 1 |
Nery, PB | 1 |
Klein, A | 1 |
Davis, DR | 1 |
Sadek, MM | 1 |
Neilipovitz, D | 1 |
Johnson, CB | 1 |
Green, MS | 1 |
Redpath, C | 1 |
Miller, DC | 1 |
Beamer, P | 1 |
Billheimer, D | 1 |
Subbian, V | 1 |
Sorooshian, A | 1 |
Campbell, BS | 1 |
Mosier, JM | 1 |
Novaretti, JV | 1 |
Astur, DC | 1 |
Cavalcante, ELB | 1 |
Kaleka, CC | 1 |
Amaro, JT | 1 |
Cohen, M | 1 |
Huang, W | 1 |
Li, T | 1 |
Ling, Y | 1 |
Qian, ZP | 1 |
Zhang, YY | 1 |
Huang, D | 1 |
Xu, SB | 1 |
Liu, XH | 1 |
Xia, L | 1 |
Yang, Y | 3 |
Lu, SH | 1 |
Lu, HZ | 1 |
Zhang, R | 2 |
Ma, JX | 1 |
Tang, S | 1 |
Li, CM | 1 |
Wan, J | 1 |
Wang, JF | 1 |
Ma, JQ | 1 |
Luo, JJ | 1 |
Chen, HY | 2 |
Mi, SL | 1 |
Chen, SY | 1 |
Su, YG | 1 |
Ge, JB | 1 |
Milheiro, SA | 1 |
Gonçalves, J | 1 |
Lopes, RMRM | 1 |
Madureira, M | 1 |
Lobo, L | 1 |
Lopes, A | 1 |
Nogueira, F | 1 |
Fontinha, D | 1 |
Prudêncio, M | 1 |
M Piedade, MF | 1 |
Pinto, SN | 1 |
Florindo, PR | 1 |
Moreira, R | 1 |
Castillo-Lora, J | 1 |
Delley, MF | 1 |
Laga, SM | 1 |
Mayer, JM | 1 |
Sutjarit, N | 1 |
Thongon, N | 1 |
Weerachayaphorn, J | 1 |
Piyachaturawat, P | 1 |
Suksamrarn, A | 1 |
Suksen, K | 1 |
Papachristou, DJ | 1 |
Blair, HC | 1 |
Hu, Y | 1 |
Shen, P | 1 |
Zeng, N | 1 |
Wang, L | 3 |
Yan, D | 1 |
Cui, L | 1 |
Yang, K | 2 |
Zhai, C | 1 |
Yang, M | 1 |
Lao, X | 1 |
Sun, J | 1 |
Ma, N | 1 |
Wang, S | 1 |
Ye, W | 1 |
Guo, P | 1 |
Rahimi, S | 1 |
Singh, MP | 1 |
Gupta, J | 1 |
Nakanishi, I | 1 |
Ohkubo, K | 1 |
Shoji, Y | 1 |
Fujitaka, Y | 1 |
Shimoda, K | 1 |
Matsumoto, KI | 1 |
Fukuhara, K | 1 |
Hamada, H | 1 |
van der Boom, T | 1 |
Gruppen, EG | 1 |
Lefrandt, JD | 1 |
Connelly, MA | 1 |
Links, TP | 1 |
Dullaart, RPF | 1 |
Berry, JD | 1 |
Bedlack, R | 1 |
Mathews, D | 1 |
Agnese, W | 1 |
Apple, S | 1 |
Meloncelli, S | 1 |
Divizia, M | 1 |
Germani, G | 1 |
Adefegha, SA | 1 |
Bottari, NB | 1 |
Leal, DB | 1 |
de Andrade, CM | 1 |
Schetinger, MR | 1 |
Martínez-Velasco, A | 1 |
Perez-Ortiz, AC | 1 |
Antonio-Aguirre, B | 1 |
Martínez-Villaseñor, L | 1 |
Lira-Romero, E | 1 |
Palacio-Pastrana, C | 1 |
Zenteno, JC | 1 |
Ramirez, I | 1 |
Zepeda-Palacio, C | 1 |
Mendoza-Velásquez, C | 1 |
Camacho-Ordóñez, A | 1 |
Ortiz Bibriesca, DM | 1 |
Estrada-Mena, FJ | 1 |
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Thompson, LC | 1 |
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Schladweiler, MC | 1 |
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Steinhart, C | 1 |
Shen, Y | 1 |
Lu, H | 1 |
Mansuri, A | 1 |
Lokhande, K | 1 |
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Junnarkar, M | 1 |
Pawar, S | 1 |
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Basudan, AM | 1 |
Niazy, AA | 1 |
van den Beucken, JJJP | 1 |
Jansen, JA | 1 |
Alghamdi, HS | 1 |
Guo, X | 1 |
Cao, Y | 1 |
Jia, X | 1 |
Xu, S | 1 |
Lu, C | 2 |
Zhu, H | 3 |
Melku, M | 1 |
Abebe, G | 1 |
Teketel, A | 1 |
Asrie, F | 1 |
Yalew, A | 1 |
Biadgo, B | 1 |
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Damtie, D | 1 |
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Ahmed, MFE | 1 |
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Kehrenberg, C | 1 |
Abd El-Wahab, A | 1 |
Volkmann, N | 1 |
Kemper, N | 1 |
Schulz, J | 1 |
Hu, MY | 1 |
Wu, YN | 1 |
McEvoy, MP | 1 |
Wang, YF | 1 |
Cong, WL | 1 |
Liu, LP | 1 |
Li, XX | 1 |
Zhou, CL | 1 |
Chen, WM | 1 |
Wei, KL | 1 |
Tung, SY | 1 |
Shen, CH | 1 |
Chang, TS | 1 |
Yen, CW | 1 |
Hsieh, YY | 1 |
Chiu, WN | 1 |
Hu, JH | 1 |
Lu, SN | 1 |
Hung, CH | 1 |
Alakavuklar, MA | 1 |
Fuqua, C | 1 |
Luo, KL | 1 |
Underwood, RS | 1 |
Greenwald, I | 1 |
Elashiry, MM | 1 |
Elashiry, M | 1 |
Zeitoun, R | 1 |
Elsayed, R | 1 |
Tian, F | 1 |
Saber, SE | 1 |
Elashry, SH | 1 |
Tay, FR | 1 |
Cutler, CW | 1 |
O'Dowd, A | 1 |
Maciel, M | 1 |
Poole, ST | 1 |
Jobling, MG | 1 |
Rollenhagen, JE | 1 |
Woods, CM | 1 |
Sincock, SA | 1 |
McVeigh, AL | 1 |
Gregory, MJ | 1 |
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Prouty, MG | 1 |
Holmes, RK | 1 |
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Palevsky, PM | 1 |
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Thiessen Philbrook, H | 1 |
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Chaturvedi, V | 1 |
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Zhang, T | 1 |
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Feng, X | 2 |
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Griffith, DC | 1 |
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Perry, LM | 1 |
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Pressly, BB | 1 |
Alferiev, IS | 1 |
Chorny, M | 1 |
Brodeur, GM | 1 |
Gao, X | 2 |
Cheng, YH | 1 |
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DeSantis, AJ | 1 |
Gaponenko, V | 1 |
Majetschak, M | 1 |
Kim, DY | 1 |
Choi, MJ | 1 |
Ko, TK | 1 |
Lee, NH | 1 |
Kim, OH | 1 |
Cheon, HG | 1 |
Cai, H | 1 |
Yip, V | 1 |
Lee, MV | 1 |
Wong, S | 1 |
Saad, O | 1 |
Ma, S | 1 |
Ljumanovic, N | 1 |
Khojasteh, SC | 1 |
Kamath, AV | 1 |
Shen, BQ | 1 |
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Chanteux, H | 1 |
Gillent, E | 1 |
Bonnaillie, P | 1 |
Saunders, K | 1 |
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Dell'Aiera, S | 1 |
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Knapp, AK | 1 |
Chen, A | 1 |
Griffin-Nolan, RJ | 1 |
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Carroll, CJW | 1 |
Gray, JE | 1 |
Hoffman, AM | 1 |
Post, AK | 1 |
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Collins, SL | 1 |
Luo, Y | 1 |
Smith, MD | 1 |
Temitayo, GI | 1 |
Olawande, B | 1 |
Emmanuel, YO | 1 |
Timothy, AT | 1 |
Kehinde, O | 1 |
Susan, LF | 1 |
Ezra, L | 1 |
Joseph, OO | 1 |
Lev, S | 1 |
Desmarini, D | 1 |
Liuwantara, D | 1 |
Sorrell, TC | 1 |
Hawthorne, WJ | 1 |
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Verso, MG | 1 |
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Marrella, A | 1 |
Immordino, P | 1 |
Vitale, F | 1 |
Amodio, E | 1 |
Wang, YD | 1 |
Yao, WL | 1 |
Xin, ZM | 1 |
Han, TT | 1 |
Wang, ZG | 1 |
Chen, L | 1 |
Cai, C | 1 |
Ba, D | 1 |
Wen, S | 1 |
Tian, Q | 1 |
Lv, W | 1 |
Cheng, G | 1 |
Li, N | 1 |
Yue, XY | 1 |
Chu, WJ | 1 |
Chen, Q | 1 |
Choi, ES | 1 |
Zhao, X | 3 |
Zhou, HD | 1 |
Sun, XF | 1 |
Sharma, S | 2 |
Chhoker, S | 1 |
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Tan, ZK | 1 |
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Huang, Y | 1 |
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Wang, WM | 1 |
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Li, P | 1 |
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Yong-Yi, J | 1 |
Mei-Li, C | 1 |
Shi-Li, L | 1 |
Jian-Bo, Z | 1 |
Dan-Li, W | 1 |
Zhi-Min, G | 1 |
Ibrahim, AM | 1 |
Zakhary, SY | 1 |
Amin, SAW | 1 |
Ugurlu, M | 1 |
Fornari, VJ | 1 |
Hartmann, MSM | 1 |
Vanni, JR | 1 |
Rodriguez, R | 1 |
Langaro, MC | 1 |
Pelepenko, LE | 1 |
Zaia, AA | 1 |
Nakanjako, D | 1 |
Zalwango, F | 1 |
Wairagala, P | 1 |
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Andia Biraro, I | 1 |
Bukirwa, VD | 1 |
Mboowa, MG | 1 |
Cose, S | 1 |
Seeley, J | 1 |
Elliott, A | 1 |
Zhao, G | 1 |
Sun, P | 1 |
Hao, S | 1 |
Wang, X | 2 |
Qu, G | 1 |
Xing, Y | 1 |
Xu, X | 1 |
Maierhofer, M | 1 |
Rieger, V | 1 |
Mayr, T | 1 |
Liu, Y | 3 |
Zhang, Q | 1 |
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Dos Santos, M | 1 |
Garcia, EM | 1 |
Baisch, PRM | 1 |
Soares, MCF | 1 |
Muccillo-Baisch, AL | 1 |
da Silva Júnior, FMR | 1 |
Yu, W | 1 |
Ju, C | 1 |
Wang, K | 1 |
Zheng, Z | 1 |
Liu, H | 3 |
Gao, Y | 1 |
Martínez-Navarro, EM | 1 |
Cebrián-Tarancón, C | 1 |
Moratalla-López, N | 1 |
Lorenzo, C | 1 |
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Bermúdez de Castro, JM | 1 |
Modesto-Mata, M | 1 |
Martín-Francés, L | 1 |
García-Campos, C | 1 |
Martínez de Pinillos, M | 1 |
Martinón-Torres, M | 1 |
Hasani, M | 1 |
Wu, F | 2 |
Warriner, K | 1 |
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Gretzke, D | 1 |
Hörlein, R | 1 |
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Atzrodt, J | 1 |
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Ou, X | 1 |
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Liu, M | 2 |
Jiang, GD | 1 |
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Holloway, RW | 1 |
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Armstrong, DK | 1 |
Banerjee, S | 1 |
García-Donas, J | 1 |
Swisher, EM | 1 |
Cella, D | 1 |
Meunier, J | 1 |
Goble, S | 1 |
Cameron, T | 1 |
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Ledermann, JA | 1 |
Coleman, RL | 1 |
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Burm, R | 1 |
Govers, TM | 1 |
Vleugels, MPH | 1 |
Tuynman, JB | 1 |
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Leicht, AS | 1 |
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Gómez, MA | 1 |
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Shanmugam, S | 1 |
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Bai, Z | 1 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Effects of Losartan vs. Nebivolol vs. the Association of Both on the Progression of Aortic Root Dilation in Marfan Syndrome (MFS) With FBN1 Gene Mutations.[NCT00683124] | Phase 3 | 291 participants (Anticipated) | Interventional | 2008-07-31 | Recruiting | ||
No Pharmacokinetic Interaction Between Chlorthalidone and Losartan, in Healthy Volunteers Under Fasting Conditions, Administered in Fixed Combination Against Individual Components Administered Jointly and Separately[NCT05090449] | Phase 1 | 36 participants (Actual) | Interventional | 2019-05-01 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
3 reviews available for losartan and Pregnancy
Article | Year |
---|---|
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; | 2022 |
Angiotensin as a target for the treatment of Alzheimer's disease, anxiety and depression.
Topics: Aging; Alzheimer Disease; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inh | 2004 |
[Drug-interactions and adverse effects of losartan potassium, an angiotensin II receptor antagonist].
Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Drug Interactions; Female; Humans; Losart | 1999 |
3 trials available for losartan and Pregnancy
Article | Year |
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Differential effects of renin-angiotensine-aldosteron system inhibition, sympathoinhibition and low sodium diet on blood pressure in women with a history of preeclampsia: A double-blind, placebo-controlled cross-over trial (the PALM study).
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Cardiovascular Diseases; Cross-Over | 2022 |
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; | 2022 |
B1 kinin receptor does not contribute to vascular tone or tissue plasminogen activator release in the peripheral circulation of patients with heart failure.
Topics: Adolescent; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bradykinin B1 R | 2005 |
99 other studies available for losartan and Pregnancy
Article | Year |
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Dysregulated ACE/Ang II/Ang1-7 signaling provokes cardiovascular and inflammatory sequelae of endotoxemia in weaning preeclamptic rats.
Topics: Angiotensin II; Animals; Endotoxemia; Female; Humans; Losartan; Peptidyl-Dipeptidase A; Pioglitazone | 2022 |
Losartan impairs HTR-8/SVneo trophoblast migration through inhibition of angiotensin II-induced pro-inflammatory profile in human endometrial stromal cells.
Topics: Angiotensin II; Endometrium; Female; Humans; Losartan; Matrix Metalloproteinase 2; Pregnancy; Prolac | 2023 |
Altered local RAS in the liver increased the risk of NAFLD in male mouse offspring produced by in vitro fertilization.
Topics: Animals; Diet, High-Fat; Female; Fertilization in Vitro; Glucose; Humans; Lipids; Liver; Losartan; M | 2023 |
Methylation-reprogrammed AGTR1 results in increased vasoconstriction by angiotensin II in human umbilical cord vessel following in vitro fertilization-embryo transfer.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; An | 2019 |
The angiotensin II type I receptor contributes to impaired cerebral blood flow autoregulation caused by placental ischemia in pregnant rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Cerebrovascular Circulation; Female; Homeostasis; | 2019 |
Effects of maternal protein restriction on central and peripheral renin-angiotensin systems in male rat offspring.
Topics: Animals; Arterial Pressure; Diet, Protein-Restricted; Female; Heart Rate; Hypertension; Lactation; L | 2020 |
Use of angiotensin II receptor blocker during pregnancy: A case report.
Topics: Adult; Angiotensin Receptor Antagonists; Female; Humans; Losartan; Nephrotic Syndrome; Oligohydramni | 2021 |
Prenatal High-Sucrose Diet Induced Vascular Dysfunction in Thoracic Artery of Fetal Offspring.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Body Weight; Dietary Sucrose; Endothelium, Vascula | 2021 |
Losartan reverses COX-2-dependent vascular dysfunction in offspring of hyperglycaemic rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cyclooxygenase 2; Endothelium, Vas | 2017 |
Angiotensin receptor blockade in juvenile male rat offspring: Implications for long-term cardio-renal health.
Topics: Age Factors; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Birth Weight; Blood | 2018 |
Influence of the AT1 Receptor Antagonists Telmisartan and Losartan on Reproduction and Offspring After Paternal Exposure to Ionizing Radiation.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Female; Fetal Viability; Losartan; Male; Paternal | 2019 |
Angiotensin II-mediated vascular changes in aged offspring rats exposed to perinatal nicotine.
Topics: Acetylcholine; Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Abdom | 2013 |
Chronic vasodilation increases renal medullary PDE5A and α-ENaC through independent renin-angiotensin-aldosterone system pathways.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pr | 2013 |
Autoantibodies isolated from preeclamptic patients induce endothelial dysfunction via interaction with the angiotensin II AT1 receptor.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Autoantibodies; Caspases; Cells, Cultured; Dose-Re | 2014 |
Endothelium-dependent relaxation and angiotensin II sensitivity in experimental preeclampsia.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Cyclooxygenase 1; Cyclooxyg | 2013 |
Angiotensin II-induced cardiovascular load regulates cardiac remodeling and related gene expression in late-gestation fetal sheep.
Topics: Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cardiovascul | 2014 |
Gestational exposure to elevated testosterone levels induces hypertension via heightened vascular angiotensin II type 1 receptor signaling in rats.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Female; Hypertension, Pregnancy-Ind | 2014 |
Exposure to AT1 receptor autoantibodies during pregnancy increases susceptibility of the maternal heart to postpartum ischemia-reperfusion injury in rats.
Topics: Animals; Autoantibodies; Collagen; Female; Heart Ventricles; Losartan; Mitochondria, Heart; Pre-Ecla | 2014 |
Autoantibodies isolated from patients with preeclampsia induce soluble endoglin production from trophoblast cells via interactions with angiotensin II type 1 receptor.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Antigens, CD; Autoantibodies; Case-Control Studies; | 2015 |
Experimental gestational diabetes mellitus induces blunted vasoconstriction and functional changes in the rat aorta.
Topics: Angiotensin II; Animals; Diabetes Mellitus, Experimental; Diabetes, Gestational; Female; Humans; Los | 2014 |
[Drugs news].
Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Anti-Obesity Agents; Anticonvu | 2015 |
Activation of the Cardiac Renin-Angiotensin System in High Oxygen-Exposed Newborn Rats: Angiotensin Receptor Blockade Prevents the Developmental Programming of Cardiac Dysfunction.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Cardiomegaly; Disease Models, An | 2016 |
Angiotensin II regulation of angiotensin-converting enzymes in spontaneously hypertensive rat primary astrocyte cultures.
Topics: Angiotensin II; Animals; Anti-Arrhythmia Agents; Astrocytes; Brain; Cells, Cultured; Dose-Response R | 2016 |
Autoantibody against AT1 receptor from preeclamptic patients induces vasoconstriction through angiotensin receptor activation.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Autoantibodies; Dose-Respo | 2008 |
[Transient renal failure in a newborn due angiotensin receptor II antagonist use during pregnancy: report of a case].
Topics: Acute Kidney Injury; Adult; Angiotensin II Type 1 Receptor Blockers; Creatinine; Female; Gestational | 2008 |
Autoantibodies to the angiotensin type I receptor in response to placental ischemia and tumor necrosis factor alpha in pregnant rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Autoantibodies; Blood Pressure; Female; Hypertensi | 2008 |
Increased vascular angiotensin type 2 receptor expression and NOS-mediated mechanisms of vascular relaxation in pregnant rats.
Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Blood Pressu | 2009 |
Angiotensin II receptor blockers in pregnancy: a report of five cases.
Topics: Abnormalities, Drug-Induced; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphe | 2009 |
The uterine placental bed Renin-Angiotensin system in normal and preeclamptic pregnancy.
Topics: Alanine; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Down-Regulation; Female; Ge | 2009 |
Prenatal blockade of Ang II receptors affects neonatal rat hindbrain structure and receptor localization.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Autoradiography; Female; Fetus; | 2009 |
Expression and distribution of NADPH oxidase isoforms in human myometrium--role in angiotensin II-induced hypertrophy.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Cell Line; Female; Gene Expression; Humans; | 2010 |
The detrimental role of angiotensin receptor agonistic autoantibodies in intrauterine growth restriction seen in preeclampsia.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Autoantibodies; CHO Cells; Crice | 2009 |
Glucocorticoid-induced fetal programming alters the functional complement of angiotensin receptor subtypes within the kidney.
Topics: Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Betamethason | 2011 |
Fetal uninephrectomy in male sheep alters the systemic and renal responses to angiotensin II infusion and AT1R blockade.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Female; Heart Rate | 2011 |
Fetopathy probably associated to self-medication with a blocker of the renin-angiotensin system.
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin II Type 1 Receptor Blockers; Antimalarials; Cesarean | 2011 |
Postnatal renal abnormalities in rats exposed to losartan during lactation.
Topics: Actins; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Apoptosis; Creatinine; D | 2011 |
Impaired vascular contractility and aortic wall degeneration in fibulin-4 deficient mice: effect of angiotensin II type 1 (AT1) receptor blockade.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Aorta, Thoracic; | 2011 |
Angiotensin II type 1 receptor antagonist attenuates lung fibrosis in hyperoxia-exposed newborn rats.
Topics: Actins; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Blotting, Western; Body | 2012 |
Angiotensin II receptor antagonist reduces subsequent uterine arterial dysfunction in pregnant offspring of protein-restricted rat dams.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin II Type 1 Receptor B | 2012 |
Activating autoantibodies to the angiotensin II type I receptor play an important role in mediating hypertension in response to adoptive transfer of CD4+ T lymphocytes from placental ischemic rats.
Topics: Adoptive Transfer; Angiotensin II Type 1 Receptor Blockers; Animals; Autoantibodies; Blood Pressure; | 2012 |
Temporal alterations in vascular angiotensin receptors and vasomotor responses in offspring of protein-restricted rat dams.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Biomarkers; Blood Pressure; Diet, Protein-Restrict | 2012 |
IL-17-mediated oxidative stress is an important stimulator of AT1-AA and hypertension during pregnancy.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antibodies, Monoclonal, Murine-Derived; Antioxidan | 2012 |
Intake of high sucrose during pregnancy altered large-conductance Ca2+-activated K+ channels and vessel tone in offspring's mesenteric arteries.
Topics: Angiotensin II; Animals; Animals, Newborn; Dietary Carbohydrates; Dose-Response Relationship, Drug; | 2013 |
Vasoactive effects of erythropoietin on human placental blood vessels in vitro.
Topics: Adult; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Arteries; Captopr | 2003 |
Insulin and losartan reduce proteinuria and renal hypertrophy in the pregnant diabetic rat.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Diabetes Mellitus, Experimental; Drug Therapy, Com | 2003 |
Losartan induced fetal toxicity.
Topics: Abnormalities, Drug-Induced; Antihypertensive Agents; Female; Fetal Death; Heart Defects, Congenital | 2003 |
Effect of a perinatal high-salt diet on blood pressure control mechanisms in young Sprague-Dawley rats.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Ani | 2004 |
Temporary losartan or captopril in young SHR induces malignant hypertension despite initial normotension.
Topics: Animals; Animals, Suckling; Antihypertensive Agents; Blood Pressure; Captopril; Female; Hypertension | 2004 |
Angiotensin II receptors in the arcuate nucleus mediate stress-induced reduction of prolactin secretion in steroid-primed ovariectomized and lactating rats.
Topics: Analysis of Variance; Angiotensin Receptor Antagonists; Animals; Arcuate Nucleus of Hypothalamus; Fe | 2004 |
Induced fetal depressor or pressor responses associated with c-fos by intravenous or intracerebroventricular losartan.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Brain; Cardiovascu | 2004 |
Central angiotensin II AT1 receptors mediate fetal swallowing and pressor responses in the near-term ovine fetus.
Topics: Angiotensin II; Animals; Anti-Arrhythmia Agents; Blood Gas Analysis; Blood Pressure; Brain Chemistry | 2005 |
Distinct roles for ANG II and ANG-(1-7) in the regulation of angiotensin-converting enzyme 2 in rat astrocytes.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzym | 2006 |
Histopathological and ultrastructural effects of Losartan on embryonic rat kidney.
Topics: Animals; Apoptosis; Disease Models, Animal; Epithelial Cells; Female; Glomerular Basement Membrane; | 2005 |
Effects of intracerebroventricular losartan on angiotensin II-mediated pressor responses and c-fos expression in near-term ovine fetus.
Topics: Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressu | 2005 |
Enhanced endothelin synthesis by endothelial cells exposed to sera from pregnant rats with decreased uterine perfusion.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Cells, Cultured; Endothelial Cells; Endothelins; F | 2006 |
Renal vascular responses in an experimental model of preeclampsia.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aortic Coarctation; Blood Pressure | 2005 |
Differential effects of prenatal exposure to dexamethasone or cortisol on circulatory control mechanisms mediated by angiotensin II in the central nervous system of adult sheep.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agents; Blood Pr | 2006 |
Remodeling and angiotensin II responses of the uterine arcuate arteries of pregnant rats are altered by low- and high-sodium intake.
Topics: Aldosterone; Angiotensin II; Animals; Arteries; Dose-Response Relationship, Drug; Female; Losartan; | 2006 |
Foetal kidney maldevelopment in maternal use of angiotensin II type I receptor antagonists.
Topics: Abnormalities, Drug-Induced; Adult; Angiotensin II Type 1 Receptor Blockers; Diseases in Twins; Fema | 2006 |
Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome.
Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Animals; Antibodies; Aorta; Ao | 2006 |
Effects of i.c.v. losartan on the angiotensin II-mediated vasopressin release and hypothalamic fos expression in near-term ovine fetuses.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Female; Fetus; Hypothalamus; Imidazoles; Injections, | 2006 |
Gestational therapy with an angiotensin II receptor antagonist and transient renal failure in a premature infant.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Female; Humans; Hypertension; Inf | 2006 |
AT1 antagonist modulates activin-like kinase 5 and TGF-beta receptor II in the developing kidney.
Topics: Actins; Activin Receptors, Type I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angioten | 2006 |
In utero losartan withdrawal and subsequent development of fetal inferior vena cava thrombosis.
Topics: Angiotensin II Type 1 Receptor Blockers; Contraindications; Diabetes Mellitus, Type 2; Female; Fetal | 2006 |
Enalapril and losartan restored blood pressure and vascular reactivity in intrauterine undernourished rats.
Topics: Animals; Antihypertensive Agents; Arterioles; Blood Glucose; Blood Pressure; Drug Antagonism; Enalap | 2007 |
Angiotensin type 1 receptor antagonist inhibits lipopolysaccharide-induced stimulation of rat microglial cells by suppressing nuclear factor kappaB and activator protein-1 activation.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Cells, Cultured; Female; Lipopolysaccharides; Losa | 2008 |
Prenatal gender-related nicotine exposure increases blood pressure response to angiotensin II in adult offspring.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Body Weight; Calcium; Enzym | 2008 |
Coronary constriction to angiotensin II is enhanced by endothelial superoxide production in sheep programmed by dexamethasone.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; An | 2008 |
AT1 blockade during lactation as a model of chronic nephropathy: mechanisms of renal injury.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Disease Models, Animal; Female; Hypertension, Rena | 2008 |
Inhibition of Angiotensin II receptors during pregnancy induces malformations in developing rat kidney.
Topics: Abnormalities, Drug-Induced; Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiote | 2008 |
A new class of antihypertensive: angiotensin II receptor antagonists.
Topics: Adult; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Dose-Response | 1995 |
Defining the susceptible period of developmental toxicity for the AT1-selective angiotensin II receptor antagonist losartan in rats.
Topics: Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Antihypertensive Agents; Arterioles; Bi | 1995 |
Evaluation of the reproductive and developmental toxicity of the AT1-selective angiotensin II receptor antagonist losartan in rats.
Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Body Weight; | 1995 |
Angiotensin II induces human placental lactogen and pregnancy-specific beta 1-glycoprotein secretion via an angiotensin AT1 receptor.
Topics: Angiotensin II; Biphenyl Compounds; Female; Humans; Imidazoles; Losartan; Oligopeptides; Placenta; P | 1994 |
Angiotensin II receptor subtypes in the adrenals of pregnant rats.
Topics: Adrenal Glands; Adrenal Medulla; Angiotensin II; Animals; Binding, Competitive; Biphenyl Compounds; | 1995 |
Angiotensin II receptors and angiotensin II stimulation of ciliary activity in human fallopian tube.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Cilia; Fallopian Tubes; Female | 1996 |
Angiotensin receptors in myometrium and myometrial vessels from uteri of women during the follicular and luteal phases of the menstrual cycle and in late pregnancy.
Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Blood Vessels; Cell Mem | 1996 |
Localization and quantitation of angiotensin AT1 and AT2 receptors in the pregnant and non-pregnant sheep uterus.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Anestrus; Angiotensin II; Angiotensin Receptor Antagonists; | 1996 |
Angiotensin II receptor expression in the conduction system and arterial duct of neonatal and adult rat hearts.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Atrioventricular Node; | 1996 |
Effects of losartan on the cardiovascular system, renal haemodynamics and function and lung liquid flow in fetal sheep.
Topics: Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Body Fluids; Female; Fetus; Im | 1996 |
Toxicokinetic analysis of losartan during gestation and lactation in the rat.
Topics: Animals; Antihypertensive Agents; Area Under Curve; Biphenyl Compounds; Female; Imidazoles; Lactatio | 1996 |
The angiotensin AT2 receptor is present in the human fetal adrenal gland throughout the second trimester of gestation.
Topics: Adrenal Glands; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Autoradiography; Binding, C | 1996 |
The role of AT1 angiotensin receptor activation in the pathogenesis of preeclampsia.
Topics: Albuminuria; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Endotoxins; Female; Fetus; L | 1998 |
Modulation of AT1 receptor-mediated contraction of rat uterine artery by AT2 receptors.
Topics: Angiotensin II; Animals; Arteries; Female; Imidazoles; Losartan; Oligopeptides; Phenylephrine; Pregn | 1998 |
Losartan: a study of pharmacovigilance data on 14,522 patients.
Topics: Age Distribution; Aged; Antihypertensive Agents; Cohort Studies; Cough; Dizziness; Female; Humans; I | 1999 |
Interactions between AT1 and AT2 receptors in uterine arteries from pregnant ewes.
Topics: Angiotensin I; Angiotensin II; Animals; Anti-Arrhythmia Agents; Arteries; Female; Hypersensitivity; | 1999 |
Angiotensin II receptor blockade during gestation attenuates collagen formation in the developing rat heart.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Birth Weight; Blotting, Western; Collagen | 1999 |
Antihypertensive treatment in early postnatal life modulates prenatal dietary influences upon blood pressure in the rat.
Topics: Analysis of Variance; Angiotensin Receptor Antagonists; Animal Nutritional Physiological Phenomena; | 2000 |
AT(1) receptor agonistic antibodies from preeclamptic patients cause vascular cells to express tissue factor.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antibodies; Cells, Cultured; CHO Cells; C | 2000 |
Glucocorticoid modulation of cardiovascular and autonomic function in preterm lambs: role of ANG II.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Autonomic Nervous Syste | 2001 |
Losartan and fetal toxic effects.
Topics: Adult; Antihypertensive Agents; Contraindications; Female; Fetal Death; Humans; Losartan; Oligohydra | 2001 |
Role of angiotensin II in altered baroreflex function of conscious rabbits during late pregnancy.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Baroreflex; Bloo | 2001 |
AT1 receptor block does not affect arterial baroreflex during pregnancy in rabbits.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Barorefle | 2001 |
Angiotensin-II-receptor inhibitors in pregnancy.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Antihypertensive Agents; Cesarean Secti | 2001 |
Fetal toxic effects and angiotensin-II-receptor antagonists.
Topics: Abnormalities, Drug-Induced; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensi | 2001 |
Blockade of angiotensin receptor subtypes in arcuate uterine artery of pregnant and postpartum rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arteries; Culture Techniques; Dose-Respon | 2001 |
AT(1) receptor blockade with losartan during gestation in Wistar rats leads to an increase in thirst and sodium appetite in their adult female offspring.
Topics: Aging; Angiotensin Receptor Antagonists; Animals; Appetite; Blood Pressure; Body Weight; Carotid Art | 2002 |
125I[Sar(1)Ile(8)] angiotensin II has a different affinity for AT(1) and AT(2) receptor subtypes in ovine tissues.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adrenal Glands; Angiotensins; Animals; Aorta; Female; Heart | 2002 |
Type-1 and type-2 angiotensin II receptors in fetal rat brain.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Biphenyl Compounds; Brai | 1991 |