losartan has been researched along with Polycythemia Vera in 3 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
Polycythemia Vera: A myeloproliferative disorder of unknown etiology, characterized by abnormal proliferation of all hematopoietic bone marrow elements and an absolute increase in red cell mass and total blood volume, associated frequently with splenomegaly, leukocytosis, and thrombocythemia. Hematopoiesis is also reactive in extramedullary sites (liver and spleen). In time myelofibrosis occurs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We assessed the clonogenic potential by colony-forming unit (CFU) assay of mononuclear cells isolated from PV JAK2 positive or JAK2 negative patients with erythrocytosis treated with enalaprilat or losartan." | 8.31 | Enalaprilat and losartan decrease erythroid precursors frequency in cells from patients with polycythemia vera. ( Astori, G; Bernardi, M; Bozza, A; Catanzaro, D; Chieregato, K; Merlo, A, 2023) |
| "We assessed the clonogenic potential by colony-forming unit (CFU) assay of mononuclear cells isolated from PV JAK2 positive or JAK2 negative patients with erythrocytosis treated with enalaprilat or losartan." | 4.31 | Enalaprilat and losartan decrease erythroid precursors frequency in cells from patients with polycythemia vera. ( Astori, G; Bernardi, M; Bozza, A; Catanzaro, D; Chieregato, K; Merlo, A, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Bozza, A | 1 |
| Bernardi, M | 1 |
| Catanzaro, D | 1 |
| Chieregato, K | 1 |
| Merlo, A | 1 |
| Astori, G | 1 |
| Ducloux, D | 1 |
| Fournier, V | 1 |
| Chalopin, JM | 1 |
| Haznedaroğlu, IC | 1 |
| Büyükaşik, Y | 1 |
3 other studies available for losartan and Polycythemia Vera
| Article | Year |
|---|---|
Enalaprilat and losartan decrease erythroid precursors frequency in cells from patients with polycythemia vera.
Topics: Enalaprilat; Erythrocytes; Humans; Losartan; Polycythemia; Polycythemia Vera | 2023 |
Postrenal transplant erythrosis: a direct role for angiotensin II.
Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Female; Humans; Imidazo | 1997 |
Current evidence for the existence of a local renin-angiotensin system affecting physiological and pathological haemopoiesis in the bone marrow.
Topics: Adult; Antihypertensive Agents; Bone Marrow; Hematopoiesis; Humans; Losartan; Male; Polycythemia Ver | 1997 |