losartan has been researched along with Pancreatitis in 10 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
Pancreatitis: INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To report a case of acute pancreatitis in a patient receiving a combination formulation of irbesartan and hydrochlorothiazide (HCTZ)." | 4.81 | Acute pancreatitis associated with angiotensin II receptor antagonists. ( Bassett, ML; Fisher, AA, 2002) |
| "To investigate the effect of ACE inhibitor, lisinopril and AT1 blocker, losartan, on the obstructive pancreatitis in rat." | 3.76 | The effect of anti-hypertensive drugs on the obstructive pancreatitis in rats. ( Ramalho, FS; Ramalho, LZ; Silva, Rde B, 2010) |
| "Angiotensin II has been shown to play a role in the pathogenesis of acute pancreatitis (AP)." | 3.75 | Involvement of redox-sensitive extracellular-regulated kinases in angiotensin II-induced interleukin-6 expression in pancreatic acinar cells. ( Chan, YC; Leung, PS, 2009) |
| "Pre-treatment with losartan, an antagonist of the angiotensin type I (AT₁) receptor, abolished NFκB activation by angiotensin II and caerulein in a dose-dependent manner." | 1.37 | Co-operative effects of angiotensin II and caerulein in NFκB activation in pancreatic acinar cells in vitro. ( Chan, YC; Leung, PS, 2011) |
| "Losartan treatment also reduced AP-associated depletion of IkappaBbeta and elevation of phospho-NF-kappaB p65 protein expression as well as the enhanced nuclear kappaB binding activity and elevated levels of kappaB-related proteins." | 1.34 | Angiotensin II type 1 receptor-dependent nuclear factor-kappaB activation-mediated proinflammatory actions in a rat model of obstructive acute pancreatitis. ( Chan, YC; Leung, PS, 2007) |
| "Induction of acute pancreatitis was achieved by hyperstimulation of two intraperitoneal (i." | 1.32 | The role of the pancreatic renin-angiotensin system in acinar digestive enzyme secretion and in acute pancreatitis. ( Cheng, CH; Leung, PS; Tsang, SW, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 6 (60.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chan, YC | 4 |
| Leung, PS | 6 |
| Silva, Rde B | 1 |
| Ramalho, FS | 1 |
| Ramalho, LZ | 1 |
| Fisher, AA | 1 |
| Bassett, ML | 1 |
| Tsang, SW | 2 |
| Ip, SP | 1 |
| Cheng, CH | 1 |
| Bosch, X | 1 |
| Birck, R | 1 |
| Keim, V | 1 |
| Fiedler, F | 1 |
| van der Woude, FJ | 1 |
| Rohmeiss, P | 1 |
1 review available for losartan and Pancreatitis
| Article | Year |
|---|---|
Acute pancreatitis associated with angiotensin II receptor antagonists.
Topics: Acute Disease; Adult; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; | 2002 |
9 other studies available for losartan and Pancreatitis
| Article | Year |
|---|---|
Involvement of redox-sensitive extracellular-regulated kinases in angiotensin II-induced interleukin-6 expression in pancreatic acinar cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blotting, Western; Cell Line; Enzy | 2009 |
The effect of anti-hypertensive drugs on the obstructive pancreatitis in rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihype | 2010 |
Co-operative effects of angiotensin II and caerulein in NFκB activation in pancreatic acinar cells in vitro.
Topics: alpha-Amylases; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antago | 2011 |
Prophylactic and therapeutic treatments with AT 1 and AT 2 receptor antagonists and their effects on changes in the severity of pancreatitis.
Topics: alpha-Amylases; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; An | 2004 |
The role of the pancreatic renin-angiotensin system in acinar digestive enzyme secretion and in acute pancreatitis.
Topics: Acute Disease; Angiotensin II Type 1 Receptor Blockers; Animals; Ceruletide; Enzymes; Gene Expressio | 2004 |
AT1 receptor antagonism ameliorates acute pancreatitis-associated pulmonary injury.
Topics: alpha-Amylases; Angiotensin II Type 1 Receptor Blockers; Animals; Capillary Permeability; Ceruletide | 2006 |
Angiotensin II type 1 receptor-dependent nuclear factor-kappaB activation-mediated proinflammatory actions in a rat model of obstructive acute pancreatitis.
Topics: Acute Disease; Angiotensin II Type 1 Receptor Blockers; Animals; Disease Models, Animal; Inflammatio | 2007 |
Losartan-induced acute pancreatitis.
Topics: Acute Disease; Adult; Antihypertensive Agents; Humans; Losartan; Male; Pancreatitis | 1997 |
Pancreatitis after losartan.
Topics: Acute Disease; Adult; Antihypertensive Agents; Diabetic Nephropathies; Female; Humans; Hypertension, | 1998 |