Page last updated: 2024-10-30

losartan and Neurofibromatosis 2

losartan has been researched along with Neurofibromatosis 2 in 1 studies

Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position

Neurofibromatosis 2: An autosomal dominant disorder characterized by a high incidence of bilateral acoustic neuromas as well as schwannomas (NEURILEMMOMA) of other cranial and peripheral nerves, and other benign intracranial tumors including meningiomas, ependymomas, spinal neurofibromas, and gliomas. The disease has been linked to mutations of the NF2 gene (GENES, NEUROFIBROMATOSIS 2) on chromosome 22 (22q12) and usually presents clinically in the first or second decade of life.

Research Excerpts

ExcerptRelevanceReference
"Hearing loss is one of the most common symptoms of neurofibromatosis type 2 (NF2) caused by vestibular schwannomas (VSs)."5.62Losartan prevents tumor-induced hearing loss and augments radiation efficacy in NF2 schwannoma rodent models. ( Brown, A; Chen, J; Datta, M; Early, S; Gao, X; Ho, WW; Jain, RK; Landegger, LD; Lee, GY; Muzikansky, A; Plotkin, SR; Ren, J; Sagers, JE; Stankovic, KM; Stemmer-Rachamimov, A; Sun, Y; Vasilijic, S; Wu, L; Xu, L; Yin, Z; Zhang, L; Zhang, N; Zhang, Y; Zhou, W, 2021)
"Hearing loss is one of the most common symptoms of neurofibromatosis type 2 (NF2) caused by vestibular schwannomas (VSs)."1.62Losartan prevents tumor-induced hearing loss and augments radiation efficacy in NF2 schwannoma rodent models. ( Brown, A; Chen, J; Datta, M; Early, S; Gao, X; Ho, WW; Jain, RK; Landegger, LD; Lee, GY; Muzikansky, A; Plotkin, SR; Ren, J; Sagers, JE; Stankovic, KM; Stemmer-Rachamimov, A; Sun, Y; Vasilijic, S; Wu, L; Xu, L; Yin, Z; Zhang, L; Zhang, N; Zhang, Y; Zhou, W, 2021)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Wu, L1
Vasilijic, S1
Sun, Y1
Chen, J1
Landegger, LD1
Zhang, Y1
Zhou, W1
Ren, J1
Early, S1
Yin, Z1
Ho, WW1
Zhang, N1
Gao, X1
Lee, GY1
Datta, M1
Sagers, JE1
Brown, A1
Muzikansky, A1
Stemmer-Rachamimov, A1
Zhang, L1
Plotkin, SR1
Jain, RK1
Stankovic, KM1
Xu, L1

Other Studies

1 other study available for losartan and Neurofibromatosis 2

ArticleYear
Losartan prevents tumor-induced hearing loss and augments radiation efficacy in NF2 schwannoma rodent models.
    Science translational medicine, 2021, 07-14, Volume: 13, Issue:602

    Topics: Animals; Hearing Loss; Humans; Losartan; Mice; Neurilemmoma; Neurofibromatosis 2; Prospective Studie

2021