Page last updated: 2024-10-30

losartan and Nephritis

losartan has been researched along with Nephritis in 9 studies

Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position

Nephritis: Inflammation of any part of the KIDNEY.

Research Excerpts

ExcerptRelevanceReference
"The FANTASTIC is a clinical study to provide: (1) the reno-protective effect of fimasartan; and (2) the target BP to reduce adverse outcomes in hypertensive diabetic CKD with overt proteinuria."9.24FimAsartaN proTeinuriA SusTaIned reduCtion in comparison with losartan in diabetic chronic kidney disease (FANTASTIC): study protocol for randomized controlled trial. ( Chin, HJ; Kim, JY; Kim, YJ; Park, S; Ryu, DR; Son, JW; Yoo, TH, 2017)
"The FANTASTIC is a clinical study to provide: (1) the reno-protective effect of fimasartan; and (2) the target BP to reduce adverse outcomes in hypertensive diabetic CKD with overt proteinuria."5.24FimAsartaN proTeinuriA SusTaIned reduCtion in comparison with losartan in diabetic chronic kidney disease (FANTASTIC): study protocol for randomized controlled trial. ( Chin, HJ; Kim, JY; Kim, YJ; Park, S; Ryu, DR; Son, JW; Yoo, TH, 2017)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's7 (77.78)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Costantino, VV1
Gil Lorenzo, AF1
Bocanegra, V1
Vallés, PG1
Kim, JY1
Son, JW1
Park, S1
Yoo, TH1
Kim, YJ1
Ryu, DR1
Chin, HJ1
Ougaard, ME1
Jensen, HE1
Thuen, ID1
Petersen, EG1
Kvist, PH1
Ávila, VF1
Foresto-Neto, O1
Arias, SCA1
Faustino, VD1
Malheiros, DMAC1
Camara, NOS1
Zatz, R1
Fujihara, CK1
Zhu, J1
Zhang, Y1
Yang, C1
Della Penna, SL2
Rosón, MI2
Toblli, JE2
Fernández, BE2
Cao, G1
Gorzalczany, S1
Pandolfo, M1
Kim, JM1
Heo, HS1
Choi, YJ1
Ye, BH1
Mi Ha, Y1
Seo, AY1
Yu, BP1
Leeuwenburgh, C1
Chung, HY1
Carter, CS1
Chiang, WC1
Lin, SL1
Chen, YM1
Wu, KD1
Tsai, TJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT02620306]Phase 3351 participants (Actual)Interventional2016-02-11Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for losartan and Nephritis

ArticleYear
Molecular Mechanisms of Hypertensive Nephropathy: Renoprotective Effect of Losartan through Hsp70.
    Cells, 2021, 11-12, Volume: 10, Issue:11

    Topics: Animals; Epithelial-Mesenchymal Transition; HSP70 Heat-Shock Proteins; Humans; Hypertension, Renal;

2021
Role of angiotensin II and oxidative stress in renal inflammation by hypernatremia: benefits of atrial natriuretic peptide, losartan, and tempol.
    Free radical research, 2015, Volume: 49, Issue:4

    Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Cyclic N-Oxides; Humans; Hypernatremia; Losartan

2015

Trials

1 trial available for losartan and Nephritis

ArticleYear
FimAsartaN proTeinuriA SusTaIned reduCtion in comparison with losartan in diabetic chronic kidney disease (FANTASTIC): study protocol for randomized controlled trial.
    Trials, 2017, Dec-29, Volume: 18, Issue:1

    Topics: Adult; Aged; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Clinical Trials, Phase III

2017

Other Studies

6 other studies available for losartan and Nephritis

ArticleYear
Inhibitors of the renin-angiotensin system ameliorates clinical and pathological aspects of experimentally induced nephrotoxic serum nephritis.
    Renal failure, 2018, Volume: 40, Issue:1

    Topics: Albuminuria; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Di

2018
Pathogenic role of angiotensin II and the NF-κB system in a model of malignant hypertensive nephrosclerosis.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2019, Volume: 42, Issue:6

    Topics: Albuminuria; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Arterioles; Female; G

2019
Protective effect of 3-n-butylphthalide against hypertensive nephropathy in spontaneously hypertensive rats.
    Molecular medicine reports, 2015, Volume: 11, Issue:2

    Topics: Albumins; Animals; Antihypertensive Agents; Benzofurans; Blood Pressure; Blood Urea Nitrogen; Drugs,

2015
Different protective actions of losartan and tempol on the renal inflammatory response to acute sodium overload.
    Journal of cellular physiology, 2010, Volume: 224, Issue:1

    Topics: Actins; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Blood Pressu

2010
Inhibition of NF-κB-induced inflammatory responses by angiotensin II antagonists in aged rat kidney.
    Experimental gerontology, 2011, Volume: 46, Issue:7

    Topics: Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibi

2011
Urinary kallikrein excretion is related to renal function change and inflammatory status in chronic kidney disease patients receiving angiotensin II receptor blocker treatment.
    Nephrology (Carlton, Vic.), 2008, Volume: 13, Issue:3

    Topics: Angiotensin II Type 1 Receptor Blockers; Biomarkers; Chemokine CCL2; Cytokines; Female; Follow-Up St

2008