losartan has been researched along with Nephritis, Interstitial in 7 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
Nephritis, Interstitial: Inflammation of the interstitial tissue of the kidney. This term is generally used for primary inflammation of KIDNEY TUBULES and/or surrounding interstitium. For primary inflammation of glomerular interstitium, see GLOMERULONEPHRITIS. Infiltration of the inflammatory cells into the interstitial compartment results in EDEMA, increased spaces between the tubules, and tubular renal dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We divided 2-month-old male Sprague-Dawley rats into 4 groups, namely group 1-control, group 2-hyperoxaluria, group 3-hyperoxaluria plus losartan and group 4-losartan." | 7.71 | Effects of angiotensin II subtype 1 receptor blockade by losartan on tubulointerstitial lesions caused by hyperoxaluria. ( Angerosa, M; De Cavanaugh, EM; Ferder, L; Inserra, F; Stella, I; Toblli, JE, 2002) |
| " To determine if the TI injury accompanying cyclosporine A (CsA) nephropathy was associated with accelerated apoptosis and ischemia, we treated rats for five weeks with CsA with or without losartan (to block angiotensin II type 1 receptor), or hydralazine/furosemide (H/F) (protocol #1)." | 7.70 | Accelerated apoptosis characterizes cyclosporine-associated interstitial fibrosis. ( Andoh, TF; Bennett, WM; Couser, WG; Johnson, RJ; Pichler, RH; Shankland, SJ; Thomas, SE, 1998) |
| "100 healthy Sprague-Dawley rats were randomly divided into 5 groups: Unilateral ureteral obstruction (UUO) group, sham-operation (SOR) group, Radix Notoginseng (RN) group, compound Radix Notoginseng (CRN) group and Losartan (ARB) group." | 3.78 | [Investigate the effects of compound radix notoginseng on renal interstitial fibrosis and kidney-targeting treatment]. ( Fan, JM; Feng, SG; Liu, HC; Xie, XS; Yuan, W; Zhang, CL; Zhang, ZY; Zuo, C, 2012) |
| "We divided 2-month-old male Sprague-Dawley rats into 4 groups, namely group 1-control, group 2-hyperoxaluria, group 3-hyperoxaluria plus losartan and group 4-losartan." | 3.71 | Effects of angiotensin II subtype 1 receptor blockade by losartan on tubulointerstitial lesions caused by hyperoxaluria. ( Angerosa, M; De Cavanaugh, EM; Ferder, L; Inserra, F; Stella, I; Toblli, JE, 2002) |
| " To determine if the TI injury accompanying cyclosporine A (CsA) nephropathy was associated with accelerated apoptosis and ischemia, we treated rats for five weeks with CsA with or without losartan (to block angiotensin II type 1 receptor), or hydralazine/furosemide (H/F) (protocol #1)." | 3.70 | Accelerated apoptosis characterizes cyclosporine-associated interstitial fibrosis. ( Andoh, TF; Bennett, WM; Couser, WG; Johnson, RJ; Pichler, RH; Shankland, SJ; Thomas, SE, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, L | 1 |
| Chen, DQ | 1 |
| Wang, M | 1 |
| Liu, D | 1 |
| Chen, H | 1 |
| Dou, F | 1 |
| Vaziri, ND | 1 |
| Zhao, YY | 1 |
| Perico, N | 1 |
| Cattaneo, D | 1 |
| Remuzzi, G | 1 |
| Xie, XS | 1 |
| Zuo, C | 1 |
| Zhang, ZY | 1 |
| Liu, HC | 1 |
| Feng, SG | 1 |
| Zhang, CL | 1 |
| Yuan, W | 1 |
| Fan, JM | 1 |
| Toblli, JE | 1 |
| Ferder, L | 1 |
| Stella, I | 1 |
| De Cavanaugh, EM | 1 |
| Angerosa, M | 1 |
| Inserra, F | 1 |
| Sun, BK | 1 |
| Li, C | 1 |
| Lim, SW | 1 |
| Choi, BS | 1 |
| Lee, SH | 1 |
| Kim, IS | 1 |
| Kim, YS | 1 |
| Bang, BK | 1 |
| Yang, CW | 1 |
| Thomas, SE | 1 |
| Andoh, TF | 1 |
| Pichler, RH | 1 |
| Shankland, SJ | 1 |
| Couser, WG | 1 |
| Bennett, WM | 1 |
| Johnson, RJ | 1 |
| Zimpelmann, J | 1 |
| Kumar, D | 1 |
| Levine, DZ | 1 |
| Wehbi, G | 1 |
| Imig, JD | 1 |
| Navar, LG | 1 |
| Burns, KD | 1 |
7 other studies available for losartan and Nephritis, Interstitial
| Article | Year |
|---|---|
Role of RAS/Wnt/β-catenin axis activation in the pathogenesis of podocyte injury and tubulo-interstitial nephropathy.
Topics: Angiotensin II; beta Catenin; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Dose-Respons | 2017 |
Kidney injury molecule 1: in search of biomarkers of chronic tubulointerstitial damage and disease progression.
Topics: Animals; Antihypertensive Agents; Biomarkers; Chronic Disease; Disease Models, Animal; Disease Progr | 2009 |
[Investigate the effects of compound radix notoginseng on renal interstitial fibrosis and kidney-targeting treatment].
Topics: Actins; Animals; Collagen Type I; Drugs, Chinese Herbal; Fibronectins; Fibrosis; Kidney; Losartan; M | 2012 |
Effects of angiotensin II subtype 1 receptor blockade by losartan on tubulointerstitial lesions caused by hyperoxaluria.
Topics: Angiotensin Receptor Antagonists; Animals; Atrophy; Fibrosis; Hyperoxaluria; Kidney Tubules; Losarta | 2002 |
Blockade of angiotensin II with losartan attenuates transforming growth factor-beta1 inducible gene-h3 (betaig-h3) expression in a model of chronic cyclosporine nephrotoxicity.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blotting, Northern; Cyclosporine; Disease Models, | 2005 |
Accelerated apoptosis characterizes cyclosporine-associated interstitial fibrosis.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Apoptosis; Argin | 1998 |
Early diabetes mellitus stimulates proximal tubule renin mRNA expression in the rat.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Antihypertensive Agents; | 2000 |