losartan has been researched along with Muscle Relaxation in 10 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We have investigated the effects of a long-acting calcium antagonist, benidipine, and an angiotensin AT(1) receptor antagonist, losartan, on the vascular damage observed in OLETF rats, an animal model of metabolic syndrome." | 7.74 | Comparison of vasculoprotective effects of benidipine and losartan in a rat model of metabolic syndrome. ( Furuta, K; Hongo, M; Ishizaka, N; Koike, K; Matsuzaki, G; Nagai, R; Saito, K; Sakurai, R, 2008) |
| "We tested the hypothesis that angiotensin II-induced hypertension is associated with an increase in vascular ." | 7.69 | Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone. ( Freeman, BA; Griendling, KK; Harrison, DG; Kurz, S; Münzel, T; Rajagopalan, S; Tarpey, M, 1996) |
| "Adjuvant arthritis was induced in rats with and without prophylactic losartan (AT1R antagonist) treatment." | 3.79 | Angiotensin II Type 1 receptor blockade protects endothelium-derived hyperpolarising factor-mediated relaxation in a rat model of monoarthritis. ( Dunning, L; Ferrell, WR; Lockhart, JC; Mackenzie, A, 2013) |
| " We have investigated the effects of a long-acting calcium antagonist, benidipine, and an angiotensin AT(1) receptor antagonist, losartan, on the vascular damage observed in OLETF rats, an animal model of metabolic syndrome." | 3.74 | Comparison of vasculoprotective effects of benidipine and losartan in a rat model of metabolic syndrome. ( Furuta, K; Hongo, M; Ishizaka, N; Koike, K; Matsuzaki, G; Nagai, R; Saito, K; Sakurai, R, 2008) |
| "We tested the hypothesis that angiotensin II-induced hypertension is associated with an increase in vascular ." | 3.69 | Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone. ( Freeman, BA; Griendling, KK; Harrison, DG; Kurz, S; Münzel, T; Rajagopalan, S; Tarpey, M, 1996) |
| "Losartan treatment prevented these SAD-induced changes." | 1.48 | Effects of losartan on vasomotor function and canonical transient receptor potential channels in the aortas of sinoaortic denervation rats. ( Liang, M; Liu, Y; Miao, F; Wu, H; Zhong, W, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liang, M | 1 |
| Zhong, W | 1 |
| Miao, F | 1 |
| Wu, H | 1 |
| Liu, Y | 1 |
| Mackenzie, A | 1 |
| Dunning, L | 1 |
| Ferrell, WR | 1 |
| Lockhart, JC | 1 |
| Ramos-Filho, AC | 1 |
| Moscoso, JA | 1 |
| Calmasini, F | 1 |
| Faria, Jde A | 1 |
| Anhê, GF | 1 |
| Mónica, FZ | 1 |
| Antunes, E | 1 |
| Lunder, M | 1 |
| Janić, M | 1 |
| Žiberna, L | 1 |
| Drevenšek, G | 1 |
| Šabovič, M | 1 |
| de Godoy, MA | 1 |
| de Oliveira, AM | 1 |
| Rattan, S | 1 |
| Mallem, MY | 1 |
| Reculeau, O | 1 |
| Le Coz, O | 1 |
| Gogny, M | 1 |
| Desfontis, JC | 1 |
| Matsuzaki, G | 1 |
| Ishizaka, N | 1 |
| Furuta, K | 1 |
| Hongo, M | 1 |
| Saito, K | 1 |
| Sakurai, R | 1 |
| Koike, K | 1 |
| Nagai, R | 1 |
| Yang, Z | 1 |
| Arnet, U | 1 |
| von Segesser, L | 1 |
| Siebenmann, R | 1 |
| Turina, M | 1 |
| Lüscher, TF | 1 |
| Rajagopalan, S | 1 |
| Kurz, S | 1 |
| Münzel, T | 1 |
| Tarpey, M | 1 |
| Freeman, BA | 1 |
| Griendling, KK | 1 |
| Harrison, DG | 1 |
| Kähönen, M | 1 |
| Tolvanen, JP | 1 |
| Kalliovalkama, J | 1 |
| Wu, X | 1 |
| Karjala, K | 1 |
| Mäkynen, H | 1 |
| Pörsti, I | 1 |
10 other studies available for losartan and Muscle Relaxation
| Article | Year |
|---|---|
Effects of losartan on vasomotor function and canonical transient receptor potential channels in the aortas of sinoaortic denervation rats.
Topics: Acetylcholine; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Denervation; Endot | 2018 |
Angiotensin II Type 1 receptor blockade protects endothelium-derived hyperpolarising factor-mediated relaxation in a rat model of monoarthritis.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Arteries; Arthritis, Experimental; Aspirin; Charyb | 2013 |
Blockade of renin-angiotensin system prevents micturition dysfunction in renovascular hypertensive rats.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Animals; Antihypertensive Agents; Atenolol; Blood Press | 2014 |
A low-dose atorvastatin and losartan combination directly improves aortic ring relaxation and diminishes ischaemic-reperfusion injury in isolated rat hearts.
Topics: Analysis of Variance; Animals; Aorta; Atorvastatin; Coronary Vessels; Dose-Response Relationship, Dr | 2012 |
Angiotensin II-induced relaxation of anococcygeus smooth muscle via desensitization of AT1 receptor, and activation of AT2 receptor associated with nitric-oxide synthase pathway.
Topics: Adenine; Angiotensin II; Animals; Blotting, Western; CD13 Antigens; Drug Interactions; Glutamyl Amin | 2004 |
Low-affinity state beta1-adrenoceptor-induced vasodilation in SHR.
Topics: Adrenergic beta-1 Receptor Agonists; Alprenolol; Animals; Aorta; Blood Pressure; Dose-Response Relat | 2005 |
Comparison of vasculoprotective effects of benidipine and losartan in a rat model of metabolic syndrome.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta, Thoracic; Calcium | 2008 |
Different effects of angiotensin-converting enzyme inhibition in human arteries and veins.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Com | 1993 |
Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone.
Topics: Acetylcholine; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Arginine; Biphenyl Compounds | 1996 |
Losartan and enalapril therapies enhance vasodilatation in the mesenteric artery of spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Diclofenac; Enalapril; Endothelium; E | 1999 |