losartan has been researched along with Mucopolysaccharidosis I in 3 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
Mucopolysaccharidosis I: Systemic lysosomal storage disease caused by a deficiency of alpha-L-iduronidase (IDURONIDASE) and characterized by progressive physical deterioration with urinary excretion of DERMATAN SULFATE and HEPARAN SULFATE. There are three recognized phenotypes representing a spectrum of clinical severity from severe to mild: Hurler syndrome, Hurler-Scheie syndrome and Scheie syndrome (formerly mucopolysaccharidosis V). Symptoms may include DWARFISM; hepatosplenomegaly; thick, coarse facial features with low nasal bridge; corneal clouding; cardiac complications; and noisy breathing.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (66.67) | 24.3611 |
2020's | 1 (33.33) | 2.80 |
Authors | Studies |
---|---|
Gonzalez, EA | 2 |
Tobar Leitão, SA | 1 |
Soares, DDS | 1 |
Tavares, AMV | 1 |
Giugliani, R | 2 |
Baldo, G | 2 |
Matte, U | 2 |
Osborn, MJ | 1 |
Webber, BR | 1 |
McElmurry, RT | 1 |
Rudser, KD | 1 |
DeFeo, AP | 1 |
Muradian, M | 1 |
Petryk, A | 1 |
Hallgrimsson, B | 1 |
Blazar, BR | 1 |
Tolar, J | 1 |
Braunlin, EA | 1 |
Tavares, AM | 1 |
Poletto, E | 1 |
3 other studies available for losartan and Mucopolysaccharidosis I
Article | Year |
---|---|
Cardiac pathology in mucopolysaccharidosis I mice: Losartan modifies ERK1/2 activation during cardiac remodeling.
Topics: Animals; Disease Models, Animal; Echocardiography; Female; Heart Diseases; Iduronidase; Losartan; Ma | 2021 |
Angiotensin receptor blockade mediated amelioration of mucopolysaccharidosis type I cardiac and craniofacial pathology.
Topics: Angiotensin Receptor Antagonists; Animals; Craniofacial Abnormalities; Disease Models, Animal; Femal | 2017 |
Losartan improves aortic dilatation and cardiovascular disease in mucopolysaccharidosis I.
Topics: Aortic Diseases; Cardiovascular Diseases; Dilatation; Humans; Losartan; Mucopolysaccharidosis I | 2017 |