Page last updated: 2024-10-30

losartan and Mucopolysaccharidosis I

losartan has been researched along with Mucopolysaccharidosis I in 3 studies

Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position

Mucopolysaccharidosis I: Systemic lysosomal storage disease caused by a deficiency of alpha-L-iduronidase (IDURONIDASE) and characterized by progressive physical deterioration with urinary excretion of DERMATAN SULFATE and HEPARAN SULFATE. There are three recognized phenotypes representing a spectrum of clinical severity from severe to mild: Hurler syndrome, Hurler-Scheie syndrome and Scheie syndrome (formerly mucopolysaccharidosis V). Symptoms may include DWARFISM; hepatosplenomegaly; thick, coarse facial features with low nasal bridge; corneal clouding; cardiac complications; and noisy breathing.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Gonzalez, EA2
Tobar Leitão, SA1
Soares, DDS1
Tavares, AMV1
Giugliani, R2
Baldo, G2
Matte, U2
Osborn, MJ1
Webber, BR1
McElmurry, RT1
Rudser, KD1
DeFeo, AP1
Muradian, M1
Petryk, A1
Hallgrimsson, B1
Blazar, BR1
Tolar, J1
Braunlin, EA1
Tavares, AM1
Poletto, E1

Other Studies

3 other studies available for losartan and Mucopolysaccharidosis I

ArticleYear
Cardiac pathology in mucopolysaccharidosis I mice: Losartan modifies ERK1/2 activation during cardiac remodeling.
    Journal of inherited metabolic disease, 2021, Volume: 44, Issue:3

    Topics: Animals; Disease Models, Animal; Echocardiography; Female; Heart Diseases; Iduronidase; Losartan; Ma

2021
Angiotensin receptor blockade mediated amelioration of mucopolysaccharidosis type I cardiac and craniofacial pathology.
    Journal of inherited metabolic disease, 2017, Volume: 40, Issue:2

    Topics: Angiotensin Receptor Antagonists; Animals; Craniofacial Abnormalities; Disease Models, Animal; Femal

2017
Losartan improves aortic dilatation and cardiovascular disease in mucopolysaccharidosis I.
    Journal of inherited metabolic disease, 2017, Volume: 40, Issue:3

    Topics: Aortic Diseases; Cardiovascular Diseases; Dilatation; Humans; Losartan; Mucopolysaccharidosis I

2017