losartan has been researched along with Lung Diseases in 6 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
Lung Diseases: Pathological processes involving any part of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a model of fat embolism using triolein-treated rats, we have reported that the acute pulmonary histopathological changes at 48 hrs were ameliorated by the angiotensin AT1 receptor blocker losartan, the angiotensin converting enzyme inhibitor captopril, and the direct renin inhibitor aliskiren." | 1.48 | Evidence for angiotensin mediation of the late histopathological effects of pulmonary fat embolism: Protection by losartan in a rat model. ( Arif, D; Bass, D; Davis, MG; England, JP; Fletcher, A; Jain, A; Molteni, A; Poisner, A, 2018) |
| "Treatment with enalapril or losartan reduced the lipid peroxidation in lung and brain tissues, while preserving the tissue glutathione content and plasma antioxidant capacity." | 1.40 | The effects of enalapril and losartan on mechanical ventilation-induced sympathoadrenal activation and oxidative stress in rats. ( Kirichenko, N; Kwon, OS; Llinas, K; Powers, SK; Sakarya, Y; Scarpace, PJ; Smuder, AJ; Sollanek, KJ; Talbert, EE; Toklu, HZ; Tümer, N; Wiggs, MP, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Poisner, A | 1 |
| Bass, D | 1 |
| Fletcher, A | 1 |
| Jain, A | 1 |
| England, JP | 1 |
| Davis, MG | 1 |
| Arif, D | 1 |
| Molteni, A | 1 |
| Toklu, HZ | 1 |
| Kwon, OS | 1 |
| Sakarya, Y | 1 |
| Powers, SK | 1 |
| Llinas, K | 1 |
| Kirichenko, N | 1 |
| Sollanek, KJ | 1 |
| Wiggs, MP | 1 |
| Smuder, AJ | 1 |
| Talbert, EE | 1 |
| Scarpace, PJ | 1 |
| Tümer, N | 1 |
| Van Eeden, S | 1 |
| Leipsic, J | 1 |
| Paul Man, SF | 1 |
| Sin, DD | 1 |
| Chan, YC | 1 |
| Leung, PS | 1 |
| Habashi, JP | 1 |
| Judge, DP | 1 |
| Holm, TM | 1 |
| Cohn, RD | 1 |
| Loeys, BL | 1 |
| Cooper, TK | 1 |
| Myers, L | 1 |
| Klein, EC | 1 |
| Liu, G | 1 |
| Calvi, C | 1 |
| Podowski, M | 1 |
| Neptune, ER | 1 |
| Halushka, MK | 1 |
| Bedja, D | 1 |
| Gabrielson, K | 1 |
| Rifkin, DB | 1 |
| Carta, L | 1 |
| Ramirez, F | 1 |
| Huso, DL | 1 |
| Dietz, HC | 1 |
| Wösten-van Asperen, RM | 1 |
| Lutter, R | 1 |
| Haitsma, JJ | 1 |
| Merkus, MP | 1 |
| van Woensel, JB | 1 |
| van der Loos, CM | 1 |
| Florquin, S | 1 |
| Lachmann, B | 1 |
| Bos, AP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Losartan vs. Nebivolol vs. the Association of Both on the Progression of Aortic Root Dilation in Marfan Syndrome (MFS) With FBN1 Gene Mutations.[NCT00683124] | Phase 3 | 291 participants (Anticipated) | Interventional | 2008-07-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for losartan and Lung Diseases
| Article | Year |
|---|---|
The relationship between lung inflammation and cardiovascular disease.
Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Animals; Cardiovascular Diseas | 2012 |
5 other studies available for losartan and Lung Diseases
| Article | Year |
|---|---|
Evidence for angiotensin mediation of the late histopathological effects of pulmonary fat embolism: Protection by losartan in a rat model.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Embolism, Fat; Losartan; Lung Diseases; Rats; Reni | 2018 |
The effects of enalapril and losartan on mechanical ventilation-induced sympathoadrenal activation and oxidative stress in rats.
Topics: Adrenal Medulla; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; | 2014 |
AT1 receptor antagonism ameliorates acute pancreatitis-associated pulmonary injury.
Topics: alpha-Amylases; Angiotensin II Type 1 Receptor Blockers; Animals; Capillary Permeability; Ceruletide | 2006 |
Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome.
Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Animals; Antibodies; Aorta; Ao | 2006 |
ACE mediates ventilator-induced lung injury in rats via angiotensin II but not bradykinin.
Topics: Angiotensin II; Animals; Apoptosis; Bradykinin; Bronchoalveolar Lavage Fluid; Captopril; Disease Mod | 2008 |