losartan has been researched along with Limb-Girdle Muscular Dystrophies in 3 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
| Excerpt | Relevance | Reference |
|---|---|---|
| "To elucidate the reliability of MRI as a non-invasive tool for assessing in vivo muscle health and pathological amelioration in response to Losartan (Angiotensin II Type 1 receptor blocker) in DyW mice (mouse model for Laminin-deficient Congenital Muscular Dystrophy Type 1A)." | 3.81 | Magnetic Resonance Imaging Is Sensitive to Pathological Amelioration in a Model for Laminin-Deficient Congenital Muscular Dystrophy (MDC1A). ( Accorsi, A; Girgenrath, M; Kumar, A; Vohra, R; Walter, G, 2015) |
| "6 hamsters (DL) with losartan, an AT1 receptor blocker, affects D1 receptor density in the striatum and nucleus tractus solitarius (NTS) and normalizes ventilation during exposure to air, hypoxia, following hypoxia, and hypercapnia, Ventilation was evaluated using plethysmography." | 3.76 | In dystrophic hamsters losartan affects control of ventilation and dopamine D1 receptor density. ( Schlenker, EH, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| White, Z | 1 |
| Milad, N | 1 |
| Tehrani, AY | 1 |
| Chen, WW | 1 |
| Donen, G | 1 |
| Sellers, SL | 1 |
| Bernatchez, P | 1 |
| Vohra, R | 1 |
| Accorsi, A | 1 |
| Kumar, A | 1 |
| Walter, G | 1 |
| Girgenrath, M | 1 |
| Schlenker, EH | 1 |
3 other studies available for losartan and Limb-Girdle Muscular Dystrophies
| Article | Year |
|---|---|
Angiotensin II receptor blocker losartan exacerbates muscle damage and exhibits weak blood pressure-lowering activity in a dysferlin-null model of Limb-Girdle muscular dystrophy type 2B.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Cholesterol; Creatine Kinase; Dise | 2019 |
Magnetic Resonance Imaging Is Sensitive to Pathological Amelioration in a Model for Laminin-Deficient Congenital Muscular Dystrophy (MDC1A).
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Disease Models, Animal; Fibrosis; Laminin; Losarta | 2015 |
In dystrophic hamsters losartan affects control of ventilation and dopamine D1 receptor density.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Body Weight; Corpus Striatum; Cricetinae; Disease | 2010 |