losartan has been researched along with Iron Overload in 3 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
Iron Overload: An excessive accumulation of iron in the body due to a greater than normal absorption of iron from the gastrointestinal tract or from parenteral injection. This may arise from idiopathic hemochromatosis, excessive iron intake, chronic alcoholism, certain types of refractory anemia, or transfusional hemosiderosis. (From Churchill's Illustrated Medical Dictionary, 1989)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cardiac iron deposition may be involved in the development of cardiac fibrosis induced by angiotensin II." | 7.71 | Iron overload augments angiotensin II-induced cardiac fibrosis and promotes neointima formation. ( Ishizaka, N; Mitani, H; Mori, I; Nagai, R; Ohno, M; Saito, K; Sata, M; Usui, S; Yamazaki, I, 2002) |
| "To investigate the effect of iron overload on experimental immunological liver injury in rats and the roles of losartan (LOS), which is the selective antagonist of angiotensin II receptor subtype AT1." | 3.76 | [Effect of iron overload on experimental immunological liver injury in rats and the role of angiotensin]. ( Jiang, H; Liu, H; Wang, J; Zhang, W; Zhang, Y; Zhuang, J, 2010) |
| "Cardiac iron deposition may be involved in the development of cardiac fibrosis induced by angiotensin II." | 3.71 | Iron overload augments angiotensin II-induced cardiac fibrosis and promotes neointima formation. ( Ishizaka, N; Mitani, H; Mori, I; Nagai, R; Ohno, M; Saito, K; Sata, M; Usui, S; Yamazaki, I, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhuang, J | 1 |
| Zhang, Y | 1 |
| Zhang, W | 1 |
| Jiang, H | 1 |
| Liu, H | 1 |
| Wang, J | 1 |
| Mak, IT | 1 |
| Landgraf, KM | 1 |
| Chmielinska, JJ | 1 |
| Weglicki, WB | 1 |
| Ishizaka, N | 1 |
| Saito, K | 1 |
| Mitani, H | 1 |
| Yamazaki, I | 1 |
| Sata, M | 1 |
| Usui, S | 1 |
| Mori, I | 1 |
| Ohno, M | 1 |
| Nagai, R | 1 |
3 other studies available for losartan and Iron Overload
| Article | Year |
|---|---|
[Effect of iron overload on experimental immunological liver injury in rats and the role of angiotensin].
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Chemical and Drug Induced Liver In | 2010 |
Angiotensin II promotes iron accumulation and depresses PGI₂ and NO synthesis in endothelial cells: effects of losartan and propranolol analogs.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta | 2012 |
Iron overload augments angiotensin II-induced cardiac fibrosis and promotes neointima formation.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Blotting, Western; Diseas | 2002 |