losartan has been researched along with Interstitial Nephritis in 7 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
| Excerpt | Relevance | Reference |
|---|---|---|
| "We divided 2-month-old male Sprague-Dawley rats into 4 groups, namely group 1-control, group 2-hyperoxaluria, group 3-hyperoxaluria plus losartan and group 4-losartan." | 7.71 | Effects of angiotensin II subtype 1 receptor blockade by losartan on tubulointerstitial lesions caused by hyperoxaluria. ( Angerosa, M; De Cavanaugh, EM; Ferder, L; Inserra, F; Stella, I; Toblli, JE, 2002) |
| " To determine if the TI injury accompanying cyclosporine A (CsA) nephropathy was associated with accelerated apoptosis and ischemia, we treated rats for five weeks with CsA with or without losartan (to block angiotensin II type 1 receptor), or hydralazine/furosemide (H/F) (protocol #1)." | 7.70 | Accelerated apoptosis characterizes cyclosporine-associated interstitial fibrosis. ( Andoh, TF; Bennett, WM; Couser, WG; Johnson, RJ; Pichler, RH; Shankland, SJ; Thomas, SE, 1998) |
| "100 healthy Sprague-Dawley rats were randomly divided into 5 groups: Unilateral ureteral obstruction (UUO) group, sham-operation (SOR) group, Radix Notoginseng (RN) group, compound Radix Notoginseng (CRN) group and Losartan (ARB) group." | 3.78 | [Investigate the effects of compound radix notoginseng on renal interstitial fibrosis and kidney-targeting treatment]. ( Fan, JM; Feng, SG; Liu, HC; Xie, XS; Yuan, W; Zhang, CL; Zhang, ZY; Zuo, C, 2012) |
| "We divided 2-month-old male Sprague-Dawley rats into 4 groups, namely group 1-control, group 2-hyperoxaluria, group 3-hyperoxaluria plus losartan and group 4-losartan." | 3.71 | Effects of angiotensin II subtype 1 receptor blockade by losartan on tubulointerstitial lesions caused by hyperoxaluria. ( Angerosa, M; De Cavanaugh, EM; Ferder, L; Inserra, F; Stella, I; Toblli, JE, 2002) |
| " To determine if the TI injury accompanying cyclosporine A (CsA) nephropathy was associated with accelerated apoptosis and ischemia, we treated rats for five weeks with CsA with or without losartan (to block angiotensin II type 1 receptor), or hydralazine/furosemide (H/F) (protocol #1)." | 3.70 | Accelerated apoptosis characterizes cyclosporine-associated interstitial fibrosis. ( Andoh, TF; Bennett, WM; Couser, WG; Johnson, RJ; Pichler, RH; Shankland, SJ; Thomas, SE, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, L | 1 |
| Chen, DQ | 1 |
| Wang, M | 1 |
| Liu, D | 1 |
| Chen, H | 1 |
| Dou, F | 1 |
| Vaziri, ND | 1 |
| Zhao, YY | 1 |
| Perico, N | 1 |
| Cattaneo, D | 1 |
| Remuzzi, G | 1 |
| Xie, XS | 1 |
| Zuo, C | 1 |
| Zhang, ZY | 1 |
| Liu, HC | 1 |
| Feng, SG | 1 |
| Zhang, CL | 1 |
| Yuan, W | 1 |
| Fan, JM | 1 |
| Toblli, JE | 1 |
| Ferder, L | 1 |
| Stella, I | 1 |
| De Cavanaugh, EM | 1 |
| Angerosa, M | 1 |
| Inserra, F | 1 |
| Sun, BK | 1 |
| Li, C | 1 |
| Lim, SW | 1 |
| Choi, BS | 1 |
| Lee, SH | 1 |
| Kim, IS | 1 |
| Kim, YS | 1 |
| Bang, BK | 1 |
| Yang, CW | 1 |
| Thomas, SE | 1 |
| Andoh, TF | 1 |
| Pichler, RH | 1 |
| Shankland, SJ | 1 |
| Couser, WG | 1 |
| Bennett, WM | 1 |
| Johnson, RJ | 1 |
| Zimpelmann, J | 1 |
| Kumar, D | 1 |
| Levine, DZ | 1 |
| Wehbi, G | 1 |
| Imig, JD | 1 |
| Navar, LG | 1 |
| Burns, KD | 1 |
7 other studies available for losartan and Interstitial Nephritis
| Article | Year |
|---|---|
Role of RAS/Wnt/β-catenin axis activation in the pathogenesis of podocyte injury and tubulo-interstitial nephropathy.
Topics: Angiotensin II; beta Catenin; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Dose-Respons | 2017 |
Kidney injury molecule 1: in search of biomarkers of chronic tubulointerstitial damage and disease progression.
Topics: Animals; Antihypertensive Agents; Biomarkers; Chronic Disease; Disease Models, Animal; Disease Progr | 2009 |
[Investigate the effects of compound radix notoginseng on renal interstitial fibrosis and kidney-targeting treatment].
Topics: Actins; Animals; Collagen Type I; Drugs, Chinese Herbal; Fibronectins; Fibrosis; Kidney; Losartan; M | 2012 |
Effects of angiotensin II subtype 1 receptor blockade by losartan on tubulointerstitial lesions caused by hyperoxaluria.
Topics: Angiotensin Receptor Antagonists; Animals; Atrophy; Fibrosis; Hyperoxaluria; Kidney Tubules; Losarta | 2002 |
Blockade of angiotensin II with losartan attenuates transforming growth factor-beta1 inducible gene-h3 (betaig-h3) expression in a model of chronic cyclosporine nephrotoxicity.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blotting, Northern; Cyclosporine; Disease Models, | 2005 |
Accelerated apoptosis characterizes cyclosporine-associated interstitial fibrosis.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Apoptosis; Argin | 1998 |
Early diabetes mellitus stimulates proximal tubule renin mRNA expression in the rat.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Antihypertensive Agents; | 2000 |