losartan has been researched along with Insulinoma in 2 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
Insulinoma: A benign tumor of the PANCREATIC BETA CELLS. Insulinoma secretes excess INSULIN resulting in HYPOGLYCEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Losartan pretreatment offers protective effect against AngII-induced impairment of the GSIS of beta cells possibly by antagonizing the effects of AngII that causes increased ROS level and UCP2 expressions in beta-cells." | 1.36 | [Protective effect of losartan on insulin secretion function of RIN-m cells against angiotensin II-induced injury and the mechanism]. ( Cai, DH; Chen, H; Lu, X; Lv, J; Zhang, H, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lu, X | 1 |
| Lv, J | 1 |
| Zhang, H | 1 |
| Chen, H | 1 |
| Cai, DH | 1 |
| Chipitsyna, G | 1 |
| Gong, Q | 1 |
| Gray, CF | 1 |
| Haroon, Y | 1 |
| Kamer, E | 1 |
| Arafat, HA | 1 |
2 other studies available for losartan and Insulinoma
| Article | Year |
|---|---|
[Protective effect of losartan on insulin secretion function of RIN-m cells against angiotensin II-induced injury and the mechanism].
Topics: Angiotensin II; Animals; Antihypertensive Agents; Cell Line, Tumor; Insulin-Secreting Cells; Insulin | 2010 |
Induction of monocyte chemoattractant protein-1 expression by angiotensin II in the pancreatic islets and beta-cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Line, Tumor; Chemokine CCL2; | 2007 |