losartan has been researched along with Hypoglycemia in 3 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
Hypoglycemia: A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Losartan attenuated the hypoglycemia-induced rise in plasma epinephrine (6480 +/- 490 pmol/L versus placebo 8970 +/- 790 pmol/L; P <." | 9.09 | Losartan attenuates symptomatic and hormonal responses to hypoglycemia in humans. ( Born, J; Deininger, E; Dominiak, P; Fehm, HL; Fruehwald-Schultes, B; Heuer, B; Kern, W; Oltmanns, KM; Peters, A; Wellhoener, P, 2001) |
| "Losartan attenuated the hypoglycemia-induced rise in plasma epinephrine (6480 +/- 490 pmol/L versus placebo 8970 +/- 790 pmol/L; P <." | 5.09 | Losartan attenuates symptomatic and hormonal responses to hypoglycemia in humans. ( Born, J; Deininger, E; Dominiak, P; Fehm, HL; Fruehwald-Schultes, B; Heuer, B; Kern, W; Oltmanns, KM; Peters, A; Wellhoener, P, 2001) |
| "Pretreatment with losartan alone did not affect AUC(plasma epinephrine) (113+/-17 nmol x h/L), while pretreatment with PD123319 tended to reduce the response (87+/-10 nmol x h/L; P=." | 1.30 | AT1 and AT2 receptor blockade and epinephrine release during insulin-induced hypoglycemia. ( Frandsen, E; Ibsen, H; Petersen, JS; Worck, RH, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Worck, RH | 2 |
| Frandsen, E | 2 |
| Ibsen, H | 2 |
| Petersen, JS | 2 |
| Staahltoft, D | 1 |
| Jonassen, TE | 1 |
| Deininger, E | 1 |
| Oltmanns, KM | 1 |
| Wellhoener, P | 1 |
| Fruehwald-Schultes, B | 1 |
| Kern, W | 1 |
| Heuer, B | 1 |
| Dominiak, P | 1 |
| Born, J | 1 |
| Fehm, HL | 1 |
| Peters, A | 1 |
1 trial available for losartan and Hypoglycemia
| Article | Year |
|---|---|
Losartan attenuates symptomatic and hormonal responses to hypoglycemia in humans.
Topics: Adrenocorticotropic Hormone; Adult; Angiotensin Receptor Antagonists; Antihypertensive Agents; Contr | 2001 |
2 other studies available for losartan and Hypoglycemia
| Article | Year |
|---|---|
AT1 and AT2 receptor blockade and epinephrine release during insulin-induced hypoglycemia.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; | 1998 |
Brain angiotensin receptors and sympathoadrenal regulation during insulin-induced hypoglycemia.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; | 2001 |