losartan has been researched along with Hypertrophy, Right Ventricular in 7 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
Hypertrophy, Right Ventricular: Enlargement of the RIGHT VENTRICLE of the heart. This increase in ventricular mass is often attributed to PULMONARY HYPERTENSION and is a contributor to cardiovascular morbidity and mortality.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Losartan treatment improved PVS-associated pulmonary hypertension and intimal hyperplasia and might be a beneficial prophylactic therapy for patients at high risk of developing PVS after pulmonary vein surgery." | 3.80 | Losartan ameliorates "upstream" pulmonary vein vasculopathy in a piglet model of pulmonary vein stenosis. ( Caldarone, CA; Coles, JG; Fu, YY; Ide, H; Kato, H; Maynes, JT; Teichert, AM; Weisel, RD; Zhu, J, 2014) |
| "The aim of this study was to investigate the effect of prophylactic treatment with the angiotensin type 1 (AT1) receptor antagonist losartan on right ventricular hypertrophy and cardiac angiotensin 1-converting enzyme (ACE) activity in a rat model of monocrotaline-induced pulmonary hypertension." | 3.69 | Effect of losartan on right ventricular hypertrophy and cardiac angiotensin I-converting enzyme activity in pulmonary hypertensive rats. ( Fernandez-Alfonso, MS; Ganten, D; Kreutz, R; Paul, M, 1996) |
| "Treatment with bisoprolol slowed the heart rate, and treatment with losartan lowered mean arterial pressure, confirming adequate dosing, but none of the treatments improved RV function or arrested the progression of RV hypertrophy and failure compared with vehicle." | 1.40 | Effects of bisoprolol and losartan treatment in the hypertrophic and failing right heart. ( Andersen, A; Andersen, S; Bogaard, HJ; de Man, FS; Holmboe, S; Nielsen, JM; Nielsen-Kudsk, JE; Ringgaard, S; Schultz, JG; Vildbrad, MD; Vonk-Noordegraaf, A, 2014) |
| "Hypoxia produced right ventricular hypertrophy of about 100% after 3 wk, which reversed with normoxia recovery." | 1.31 | Modulation of angiotensin II receptor expression during development and regression of hypoxic pulmonary hypertension. ( Adamy, C; Adnot, S; Chassagne, C; Dubois-Randé, JL; Eddahibi, S; Marotte, F; Rideau, D; Samuel, JL; Teiger, E, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Fried, ND | 1 |
| Morris, TM | 1 |
| Whitehead, A | 1 |
| Lazartigues, E | 1 |
| Yue, X | 1 |
| Gardner, JD | 1 |
| Andersen, S | 1 |
| Schultz, JG | 1 |
| Andersen, A | 1 |
| Ringgaard, S | 1 |
| Nielsen, JM | 1 |
| Holmboe, S | 1 |
| Vildbrad, MD | 1 |
| de Man, FS | 1 |
| Bogaard, HJ | 1 |
| Vonk-Noordegraaf, A | 1 |
| Nielsen-Kudsk, JE | 1 |
| Zhu, J | 1 |
| Ide, H | 1 |
| Fu, YY | 1 |
| Teichert, AM | 1 |
| Kato, H | 1 |
| Weisel, RD | 1 |
| Maynes, JT | 1 |
| Coles, JG | 1 |
| Caldarone, CA | 1 |
| Kreutz, R | 1 |
| Fernandez-Alfonso, MS | 1 |
| Ganten, D | 1 |
| Paul, M | 1 |
| Koide, M | 1 |
| Carabello, BA | 1 |
| Conrad, CC | 1 |
| Buckley, JM | 1 |
| DeFreyte, G | 1 |
| Barnes, M | 1 |
| Tomanek, RJ | 1 |
| Wei, CC | 1 |
| Dell'Italia, LJ | 1 |
| Cooper, G | 1 |
| Zile, MR | 1 |
| Chassagne, C | 1 |
| Eddahibi, S | 1 |
| Adamy, C | 1 |
| Rideau, D | 1 |
| Marotte, F | 1 |
| Dubois-Randé, JL | 1 |
| Adnot, S | 1 |
| Samuel, JL | 1 |
| Teiger, E | 1 |
| Katz, SA | 1 |
| Opsahl, JA | 1 |
| Wernsing, SE | 1 |
| Forbis, LM | 1 |
| Smith, J | 1 |
| Heller, LJ | 1 |
7 other studies available for losartan and Hypertrophy, Right Ventricular
| Article | Year |
|---|---|
Angiotensin II type 1 receptor mediates pulmonary hypertension and right ventricular remodeling induced by inhaled nicotine.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Arterial Pressure; Disease Models, Animal; E-Cigar | 2021 |
Effects of bisoprolol and losartan treatment in the hypertrophic and failing right heart.
Topics: Adrenergic beta-1 Receptor Antagonists; Angiotensin II Type 1 Receptor Blockers; Animals; Bisoprolol | 2014 |
Losartan ameliorates "upstream" pulmonary vein vasculopathy in a piglet model of pulmonary vein stenosis.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Antigens, CD; Cadherins; Constri | 2014 |
Effect of losartan on right ventricular hypertrophy and cardiac angiotensin I-converting enzyme activity in pulmonary hypertensive rats.
Topics: Animals; Antihypertensive Agents; Biphenyl Compounds; Heart Ventricles; Hemodynamics; Humans; Hypert | 1996 |
Hypertrophic response to hemodynamic overload: role of load vs. renin-angiotensin system activation.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pr | 1999 |
Modulation of angiotensin II receptor expression during development and regression of hypoxic pulmonary hypertension.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Antihypertensive Agents | 2000 |
Myocardial renin is neither necessary nor sufficient to initiate or maintain ventricular hypertrophy.
Topics: Angiotensins; Animals; Antihypertensive Agents; Desoxycorticosterone; Hypertrophy, Left Ventricular; | 2000 |