losartan has been researched along with Hyperemia in 7 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
Hyperemia: The presence of an increased amount of blood in a body part or an organ leading to congestion or engorgement of blood vessels. Hyperemia can be due to increase of blood flow into the area (active or arterial), or due to obstruction of outflow of blood from the area (passive or venous).
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the present study, we evaluated the effects of blockade of the RAS by the angiotensin-converting enzyme inhibitor enalapril and the angiotensin II receptor blocker losartan on left ventricular (LV) and right ventricular mass and LV dilation in relation to changes in central hemodynamics during the maintenance of minoxidil and aortocaval shunt-induced cardiac hypertrophy." | 7.69 | Effects of enalapril versus losartan on regression of volume overload-induced cardiac hypertrophy in rats. ( Leenen, FH; Ruzicka, M; Yuan, B, 1994) |
| "In the femoral circulation of 19 patients with atherosclerosis and of 9 control subjects, we studied microvascular responses to reactive hyperemia, angiotensin II, acetylcholine, and sodium nitroprusside before and after the administration of intra-arterial losartan (10 mg)." | 5.09 | Acute and chronic angiotensin-1 receptor antagonism reverses endothelial dysfunction in atherosclerosis. ( Ellahham, S; Mincemoyer, R; Panza, JA; Prasad, A; Quyyumi, AA; Schenke, WH; Tupas-Habib, T; Waclawin, MA, 2000) |
| "In the present study, we evaluated the effects of blockade of the RAS by the angiotensin-converting enzyme inhibitor enalapril and the angiotensin II receptor blocker losartan on left ventricular (LV) and right ventricular mass and LV dilation in relation to changes in central hemodynamics during the maintenance of minoxidil and aortocaval shunt-induced cardiac hypertrophy." | 3.69 | Effects of enalapril versus losartan on regression of volume overload-induced cardiac hypertrophy in rats. ( Leenen, FH; Ruzicka, M; Yuan, B, 1994) |
| "Hypertension is the major risk factor for SVDs, but how hypertension damages the brain microcirculation is unclear." | 1.62 | Differential restoration of functional hyperemia by antihypertensive drug classes in hypertension-related cerebral small vessel disease. ( Dabertrand, F; Ferris, HR; Greenstein, AS; Harraz, OF; Hill-Eubanks, DC; Koide, M; Longden, TA; Nelson, MT; Wellman, GC, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Koide, M | 1 |
| Harraz, OF | 1 |
| Dabertrand, F | 1 |
| Longden, TA | 1 |
| Ferris, HR | 1 |
| Wellman, GC | 1 |
| Hill-Eubanks, DC | 1 |
| Greenstein, AS | 1 |
| Nelson, MT | 1 |
| Ziegler, MA | 1 |
| DiStasi, MR | 1 |
| Miller, SJ | 1 |
| Dalsing, MC | 1 |
| Unthank, JL | 1 |
| Kazama, K | 1 |
| Anrather, J | 1 |
| Zhou, P | 1 |
| Girouard, H | 1 |
| Frys, K | 1 |
| Milner, TA | 1 |
| Iadecola, C | 1 |
| Ruzicka, M | 3 |
| Keeley, FW | 1 |
| Leenen, FH | 3 |
| Yuan, B | 2 |
| Prasad, A | 1 |
| Tupas-Habib, T | 1 |
| Schenke, WH | 1 |
| Mincemoyer, R | 1 |
| Panza, JA | 1 |
| Waclawin, MA | 1 |
| Ellahham, S | 1 |
| Quyyumi, AA | 1 |
1 trial available for losartan and Hyperemia
| Article | Year |
|---|---|
Acute and chronic angiotensin-1 receptor antagonism reverses endothelial dysfunction in atherosclerosis.
Topics: Acetylcholine; Angiotensin II; Angiotensin Receptor Antagonists; Arteriosclerosis; Brachial Artery; | 2000 |
6 other studies available for losartan and Hyperemia
| Article | Year |
|---|---|
Differential restoration of functional hyperemia by antihypertensive drug classes in hypertension-related cerebral small vessel disease.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Cerebral Smal | 2021 |
Novel method to assess arterial insufficiency in rodent hind limb.
Topics: Animals; Feasibility Studies; Femoral Artery; Femoral Vein; Hindlimb; Hyperemia; Ligation; Losartan; | 2016 |
Angiotensin II impairs neurovascular coupling in neocortex through NADPH oxidase-derived radicals.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetophenones; Amino Acid Sequence; Angioten | 2004 |
The renin-angiotensin system and volume overload-induced changes in cardiac collagen and elastin.
Topics: Aging; Animals; Biphenyl Compounds; Blood Pressure; Collagen; Coronary Circulation; Elastin; Enalapr | 1994 |
Effects of enalapril versus losartan on regression of volume overload-induced cardiac hypertrophy in rats.
Topics: Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Volume; Body Weight; Cardiomegaly; Coron | 1994 |
Blockade of AT(1) receptors and Na(+)/H(+) exchanger and LV dysfunction after myocardial infarction in rats.
Topics: Amiloride; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Blood Volume; Drug Combination | 1999 |