losartan has been researched along with Heritable Pulmonary Arterial Hypertension in 2 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
| Excerpt | Relevance | Reference |
|---|---|---|
| "Losartan delayed disease progression, decreased right ventricular afterload and pulmonary vascular remodeling, and restored right ventricular-arterial coupling in rats with PAH." | 1.38 | Dysregulated renin-angiotensin-aldosterone system contributes to pulmonary arterial hypertension. ( Boonstra, A; de Man, FS; Dorfmüller, P; Eddahibi, S; Fadel, E; François, C; Guignabert, C; Handoko, ML; Humbert, M; Perros, F; Postmus, PE; Rain, S; Ruiter, G; Schalij, I; Simonneau, G; Tu, L; van der Velden, J; Vonk-Noordegraaf, A, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Friedberg, MK | 1 |
| Cho, MY | 1 |
| Li, J | 1 |
| Assad, RS | 1 |
| Sun, M | 1 |
| Rohailla, S | 1 |
| Honjo, O | 1 |
| Apitz, C | 1 |
| Redington, AN | 1 |
| de Man, FS | 1 |
| Tu, L | 1 |
| Handoko, ML | 1 |
| Rain, S | 1 |
| Ruiter, G | 1 |
| François, C | 1 |
| Schalij, I | 1 |
| Dorfmüller, P | 1 |
| Simonneau, G | 1 |
| Fadel, E | 1 |
| Perros, F | 1 |
| Boonstra, A | 1 |
| Postmus, PE | 1 |
| van der Velden, J | 1 |
| Vonk-Noordegraaf, A | 1 |
| Humbert, M | 1 |
| Eddahibi, S | 1 |
| Guignabert, C | 1 |
2 other studies available for losartan and Heritable Pulmonary Arterial Hypertension
| Article | Year |
|---|---|
Adverse biventricular remodeling in isolated right ventricular hypertension is mediated by increased transforming growth factor-β1 signaling and is abrogated by angiotensin receptor blockade.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Connective Tissue Growth Factor; Endoth | 2013 |
Dysregulated renin-angiotensin-aldosterone system contributes to pulmonary arterial hypertension.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Case-Control Studies; Cells, Cultured; Disease Pro | 2012 |