losartan has been researched along with Goldblatt Syndrome in 73 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to provide new insights into the role of angiotensin II and arterial pressure in the regulation of antioxidant enzyme activities in a renovascular model of cardiac hypertrophy." | 7.74 | Angiotensin II regulates cardiac hypertrophy via oxidative stress but not antioxidant enzyme activities in experimental renovascular hypertension. ( Balestrasse, KB; Gorzalczany, S; Noriega, GO; Polizio, AH; Taira, C; Tomaro, ML; Yannarelli, GG, 2008) |
| " Herein, we report two episodes of anuria and acute pulmonary edema associated with losartan treatment in a hypertensive patient with preexisting severe renal artery stenosis in a solitary kidney." | 7.72 | Two episodes of anuria and acute pulmonary edema in a losartan-treated patient with solitary kidney. ( Boz, M; Camsari, A; Kiykim, AA; Ozer, C; Yildiz, A, 2004) |
| "We report the case of a 70-year-old hypertensive man with a solitary kidney and chronic renal insufficiency who developed two episodes of transient anuria after losartan administration." | 7.71 | Repeated transient anuria following losartan administration in a patient with a solitary kidney. ( Descombes, E; Fellay, G; Maillard, JO; Regamey, C, 2001) |
| "Cardiac hypertrophy is common in hypertension but its development is influenced by angiotensin II, sodium intake aldosterone, and the time of day blood pressure (BP) is elevated." | 7.71 | Interaction between sodium intake, angiotensin II, and blood pressure as a cause of cardiac hypertrophy. ( Aubert, JF; Brunner, H; Morgan, T, 2001) |
| "Angiotensin II related cardiomyocyte necrosis and coronary vascular damage are angiotensin type 1 receptor mediated and completely preventable with the receptor antagonist losartan." | 7.69 | Prevention of angiotensin II induced myocyte necrosis and coronary vascular damage by lisinopril and losartan in the rat. ( Devineni, VR; Henegar, JR; Janicki, JS; Kabour, A, 1995) |
| "To investigate the role of angiotensin II (Ang II) in cardiovascular hypertrophy in the Goldblatt one-kidney, one clip (1-K, 1C) renal hypertensive rat." | 7.69 | Cardiovascular hypertrophy in one-kidney, one clip renal hypertensive rats: a role for angiotensin II? ( Bertram, JF; Black, MJ; Bobik, A; O'Sullivan, JB, 1994) |
| "Losartan treatment decreased systolic pressure and yellow-red collagen fiber content in all areas, whereas spironolactone treatment decreased green collagen fiber content without decreasing systolic pressure." | 5.29 | Left ventricular fibrosis in renovascular hypertensive rats. Effect of losartan and spironolactone. ( Appay, MD; Bariety, J; Heudes, D; Hinglais, N; Michel, JB; Nicoletti, A; Philippe, M; Sassy-Prigent, C, 1995) |
| " The aim of this work was to assess the impact of hemin (heme oxygenase-1 inducer) on NADPH oxidase activation, cardiac oxidative stress, and development of fibrosis in a rat model of renovascular hypertensive cardiomyopathy in comparison to an anti-hypertensive reference treatment with losartan." | 3.77 | Hemin decreases cardiac oxidative stress and fibrosis in a rat model of systemic hypertension via PI3K/Akt signalling. ( Belmokhtar, K; Bonnet, P; Eder, V; Khamis, G; Machet, MC; Vourc'h, P; Worou, ME, 2011) |
| "The aim of this study was to provide new insights into the role of angiotensin II and arterial pressure in the regulation of antioxidant enzyme activities in a renovascular model of cardiac hypertrophy." | 3.74 | Angiotensin II regulates cardiac hypertrophy via oxidative stress but not antioxidant enzyme activities in experimental renovascular hypertension. ( Balestrasse, KB; Gorzalczany, S; Noriega, GO; Polizio, AH; Taira, C; Tomaro, ML; Yannarelli, GG, 2008) |
| " Herein, we report two episodes of anuria and acute pulmonary edema associated with losartan treatment in a hypertensive patient with preexisting severe renal artery stenosis in a solitary kidney." | 3.72 | Two episodes of anuria and acute pulmonary edema in a losartan-treated patient with solitary kidney. ( Boz, M; Camsari, A; Kiykim, AA; Ozer, C; Yildiz, A, 2004) |
| "We report the case of a 70-year-old hypertensive man with a solitary kidney and chronic renal insufficiency who developed two episodes of transient anuria after losartan administration." | 3.71 | Repeated transient anuria following losartan administration in a patient with a solitary kidney. ( Descombes, E; Fellay, G; Maillard, JO; Regamey, C, 2001) |
| "Cardiac hypertrophy is common in hypertension but its development is influenced by angiotensin II, sodium intake aldosterone, and the time of day blood pressure (BP) is elevated." | 3.71 | Interaction between sodium intake, angiotensin II, and blood pressure as a cause of cardiac hypertrophy. ( Aubert, JF; Brunner, H; Morgan, T, 2001) |
| "Angiotensin II related cardiomyocyte necrosis and coronary vascular damage are angiotensin type 1 receptor mediated and completely preventable with the receptor antagonist losartan." | 3.69 | Prevention of angiotensin II induced myocyte necrosis and coronary vascular damage by lisinopril and losartan in the rat. ( Devineni, VR; Henegar, JR; Janicki, JS; Kabour, A, 1995) |
| "To investigate the role of angiotensin II (Ang II) in cardiovascular hypertrophy in the Goldblatt one-kidney, one clip (1-K, 1C) renal hypertensive rat." | 3.69 | Cardiovascular hypertrophy in one-kidney, one clip renal hypertensive rats: a role for angiotensin II? ( Bertram, JF; Black, MJ; Bobik, A; O'Sullivan, JB, 1994) |
| "Stasis-induced venous thrombus was allowed to age for 7 hours before intravenous injection of EXP3174 (10 mg/kg and 30 mg/kg)." | 1.51 | Losartan metabolite EXP3174 reduces the weight of formed thrombus in 2K1C hypertensive rats. ( Chabielska, E; Gromotowicz-Poplawska, A; Nazarko-Sadowska, J, 2019) |
| "Treatment with losartan, aliskiren, or both exerted similar antihypertensive effects." | 1.48 | Direct renin inhibition is not enough to prevent reactive oxygen species generation and vascular dysfunction in renovascular hypertension. ( Casarini, DE; Ceron, CS; Fernandes, FB; Guimaraes, DA; Martins-Oliveira, A; Oliveira, DMM; Pinheiro, LC; Rizzi, E; Tanus-Santos, JE; Tirapelli, CR, 2018) |
| "Losartan treatment increased the baroreflex sensitivity of rSNA to pressor (67%) and depressor (140%) stimuli in the 2K-1C rats." | 1.39 | Losartan reduces oxidative stress within the rostral ventrolateral medulla of rats with renovascular hypertension. ( Bergamaschi, CT; Campos, RR; Nishi, EE; Oliveira-Sales, EB; Simon, KA, 2013) |
| "Losartan treatment normalized blood pressure and prevented the changes in plasma testosterone and prolactin, sexual behavior and spermatogenesis in the 2K1C+Los group." | 1.38 | The role of AT1 receptor-mediated reproductive function in renovascular hypertension in male rats. ( Franci, CR; Lucion, AB; Sanvitto, GL; Weissheimer, KV, 2012) |
| " Chronic administration of Rut (10, 20, or 40 mg/kg/day, respectively) for 4 weeks caused a depressor effect and significantly regressed the lumen diameter and decreased the medium thickness of mesenteric arteries in hypertensive rats concomitantly with an increase in the plasma concentration of CGRP and the expression of CGRP mRNA in DRG." | 1.34 | Calcitonin gene-related Peptide-mediated depressor effect and inhibiting vascular hypertrophy of rutaecarpine in renovascular hypertensive rats. ( Chen, QQ; Deng, HW; Hu, GY; Li, D; Li, YJ; Luo, D; Qin, XP; Zeng, SY; Zhang, Z, 2007) |
| "Treatment with enalapril, losartan and their combination attenuated the observed memory deficits indicating a possible role of renin angiotensin system in cognitive function." | 1.33 | Effect of losartan and enalapril on cognitive deficit caused by Goldblatt induced hypertension. ( Ahamed, KF; Jayadev, S; Kumaran, D; Ramanathan, M; Srinivasan, J; Suresh, B, 2005) |
| "Venous thrombosis was induced by ligation of vena cava." | 1.33 | Angiotensin II enhances thrombosis development in renovascular hypertensive rats. ( Buczko, W; Chabielska, E; Mogielnicki, A; Pawlak, R; Szemraj, J, 2005) |
| "2K1C renovascular hypertension was produced in male Wistar-Kyoto(WKY) rats by placing a silver clip with an internal diameter of 0." | 1.33 | Losartan reduces monocyte chemoattractant protein-1 expression in aortic tissues of 2K1C hypertensive rats. ( Sun, M; Sun, ZL; Xie, QY; Yang, TL, 2006) |
| "The treatment with losartan not only inhibited structural and functional changes, but also the frequencies and titres of AT1R-AA was significantly lower (P < 0." | 1.32 | [Effect of losartan on produce of sera autoantibodies to angiotensin II-1 receptor in renovascular hypertension rats]. ( Jiao, XY; Liu, YX; Liu, ZB; Zhao, RR; Zhi, JM, 2003) |
| "Prognosis in Takayasu's arteritis is limited owing to renovascular hypertension." | 1.31 | Enalapril and losartan augment endogenous nitric oxide release in Takayasu's arteritis--a case report. ( Baldamus, CA; Marsen, TA; Pollok, M; Sukau, G, 2000) |
| " In contrast, chronic administration of L-arginine had no effect on the magnitude of hypertension or on the increases in renin activity and hyperangiotensinemia associated with the evolution of renal hypertension." | 1.29 | Angiotensin-(1-7) and nitric oxide interaction in renovascular hypertension. ( Dean, RH; Ferrario, CM; Fuller, SB; Nakamoto, H; Robaczewski, DL; Winicov, E, 1995) |
| "Losartan treatment decreased systolic pressure and yellow-red collagen fiber content in all areas, whereas spironolactone treatment decreased green collagen fiber content without decreasing systolic pressure." | 1.29 | Left ventricular fibrosis in renovascular hypertensive rats. Effect of losartan and spironolactone. ( Appay, MD; Bariety, J; Heudes, D; Hinglais, N; Michel, JB; Nicoletti, A; Philippe, M; Sassy-Prigent, C, 1995) |
| "Both losartan and enalapril treatments maintained conscious BP at comparably lowered levels compared to control animals (116 +/- 6 mm Hg and 113 +/- 2 mm Hg vs." | 1.29 | Effects of chronic treatment with angiotensin converting enzyme inhibitor or an angiotensin receptor antagonist in two-kidney, one-clip hypertensive rats. ( Fitzgibbon, WR; Hutchison, FN; Imamura, A; Lacy, ER; Mackenzie, HS; Ploth, DW, 1995) |
| "Losartan and enalapril treatments decreased blood pressure and induced complete regression of LVH in this model of renovascular hypertension." | 1.29 | Regression of left ventricular hypertrophy in experimental renovascular hypertension: diastolic dysfunction depends more on myocardial collagen than it does on myocardial mass. ( Cespedes, C; Dussaillant, GR; Gonzalez, H; Jalil, JE, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 30 (41.10) | 18.2507 |
| 2000's | 22 (30.14) | 29.6817 |
| 2010's | 17 (23.29) | 24.3611 |
| 2020's | 4 (5.48) | 2.80 |
| Authors | Studies |
|---|---|
| Gromotowicz-Poplawska, A | 1 |
| Nazarko-Sadowska, J | 1 |
| Chabielska, E | 4 |
| Lima, TC | 1 |
| Barbosa, MA | 1 |
| Costa, DC | 1 |
| Becker, LK | 1 |
| Cardoso, LM | 1 |
| Alzamora, AC | 1 |
| Milanez, MIO | 2 |
| Nishi, EE | 3 |
| Rocha, AA | 1 |
| Bergamaschi, CT | 3 |
| Campos, RR | 4 |
| Fernandes, MV | 1 |
| Rosso Melo, M | 1 |
| Mowry, FE | 1 |
| Lucera, GM | 1 |
| Lauar, MR | 1 |
| Frigieri, G | 1 |
| Biancardi, VC | 1 |
| Menani, JV | 1 |
| Colombari, DSA | 1 |
| Colombari, E | 1 |
| Akbar Nekooeian, A | 1 |
| Rasti Pour, A | 1 |
| Dehghani, F | 1 |
| Mashghoolozekr, E | 1 |
| Esmaeilpour, T | 1 |
| Boshra, V | 2 |
| Abbas, AM | 1 |
| Martins-Oliveira, A | 1 |
| Guimaraes, DA | 1 |
| Ceron, CS | 1 |
| Rizzi, E | 1 |
| Oliveira, DMM | 1 |
| Tirapelli, CR | 1 |
| Casarini, DE | 1 |
| Fernandes, FB | 1 |
| Pinheiro, LC | 1 |
| Tanus-Santos, JE | 1 |
| Sato, AYS | 1 |
| Futuro Neto, HA | 1 |
| Oliveira-Sales, EB | 2 |
| Simon, KA | 1 |
| Qin, YF | 1 |
| Tian, HH | 2 |
| Sun, F | 1 |
| Qin, XP | 4 |
| Braga, VA | 1 |
| Ramos-Filho, AC | 1 |
| Moscoso, JA | 1 |
| Calmasini, F | 1 |
| Faria, Jde A | 1 |
| Anhê, GF | 1 |
| Mónica, FZ | 1 |
| Antunes, E | 1 |
| Li, P | 3 |
| Zhang, F | 2 |
| Sun, HJ | 2 |
| Han, Y | 2 |
| Zhang, Y | 1 |
| Yu, XJ | 1 |
| Chen, WS | 1 |
| Gao, HL | 1 |
| Liu, KL | 1 |
| Shi, XL | 1 |
| Fan, XY | 1 |
| Jia, LL | 1 |
| Cui, W | 1 |
| Zhu, GQ | 2 |
| Liu, JJ | 1 |
| Kang, YM | 1 |
| Zeng, SY | 2 |
| Deng, SX | 1 |
| Ren, JF | 1 |
| Zheng, YB | 1 |
| Li, D | 2 |
| Li, YJ | 3 |
| Liao, DF | 2 |
| Chen, SY | 1 |
| Wu, MY | 1 |
| Ma, XJ | 1 |
| Yang, C | 1 |
| Tao, X | 1 |
| Liu, AJ | 1 |
| Su, DF | 1 |
| Liu, JG | 1 |
| Xu, Y | 1 |
| Zhou, LM | 1 |
| Li, YH | 1 |
| Fan, LM | 1 |
| Wang, W | 1 |
| Gao, XY | 1 |
| Chen, Q | 1 |
| Polizio, AH | 2 |
| Balestrasse, KB | 2 |
| Gornalusse, GG | 1 |
| Gorzalczany, SB | 1 |
| Santa-Cruz, DM | 1 |
| Yannarelli, GG | 2 |
| Peña, C | 1 |
| Tomaro, ML | 2 |
| Pereira, TM | 1 |
| Balarini, CM | 1 |
| Silva, IV | 1 |
| Cabral, AM | 1 |
| Vasquez, EC | 1 |
| Meyrelles, SS | 1 |
| Zhi, JM | 1 |
| Liu, ZB | 1 |
| Jiao, XY | 1 |
| Liu, YX | 1 |
| Zhao, RR | 1 |
| El Wakeel, GA | 1 |
| Nader, MA | 1 |
| Kalk, P | 1 |
| Sharkovska, Y | 1 |
| Kashina, E | 1 |
| von Websky, K | 1 |
| Relle, K | 1 |
| Pfab, T | 1 |
| Alter, M | 1 |
| Guillaume, P | 1 |
| Provost, D | 1 |
| Hoffmann, K | 1 |
| Fischer, Y | 1 |
| Hocher, B | 1 |
| Worou, ME | 1 |
| Belmokhtar, K | 1 |
| Bonnet, P | 1 |
| Vourc'h, P | 1 |
| Machet, MC | 1 |
| Khamis, G | 1 |
| Eder, V | 1 |
| Weissheimer, KV | 1 |
| Franci, CR | 1 |
| Lucion, AB | 1 |
| Sanvitto, GL | 1 |
| Xu, H | 1 |
| McBride, F | 1 |
| Liu, B | 1 |
| Hewinson, J | 1 |
| Toward, M | 1 |
| Hendy, EB | 1 |
| Graham, D | 1 |
| Dominiczak, AF | 1 |
| Giannotta, M | 1 |
| Waki, H | 1 |
| Ascione, R | 1 |
| Paton, JF | 1 |
| Kasparov, S | 1 |
| Chen, WW | 1 |
| Xiong, XQ | 1 |
| Ye, F | 1 |
| Saranteas, T | 1 |
| Lolis, E | 1 |
| Mourouzis, C | 1 |
| Potamianou, A | 1 |
| Tesseromatis, C | 1 |
| Varonos, D | 1 |
| Kiykim, AA | 1 |
| Boz, M | 1 |
| Ozer, C | 1 |
| Camsari, A | 1 |
| Yildiz, A | 1 |
| Srinivasan, J | 1 |
| Jayadev, S | 1 |
| Kumaran, D | 1 |
| Ahamed, KF | 1 |
| Suresh, B | 1 |
| Ramanathan, M | 1 |
| Mogielnicki, A | 2 |
| Pawlak, R | 1 |
| Szemraj, J | 1 |
| Buczko, W | 3 |
| Xie, QY | 1 |
| Sun, M | 1 |
| Yang, TL | 1 |
| Sun, ZL | 1 |
| Kamińska, M | 1 |
| Stankiewicz, A | 1 |
| Kramkowski, K | 1 |
| Domaniewski, T | 1 |
| Tanemoto, M | 1 |
| Takase, K | 1 |
| Yamada, T | 1 |
| Satoh, A | 1 |
| Abe, T | 1 |
| Ito, S | 1 |
| Chen, QQ | 1 |
| Luo, D | 1 |
| Zhang, Z | 1 |
| Hu, GY | 1 |
| Deng, HW | 1 |
| Noriega, GO | 1 |
| Gorzalczany, S | 1 |
| Taira, C | 1 |
| Nakamoto, H | 1 |
| Ferrario, CM | 1 |
| Fuller, SB | 1 |
| Robaczewski, DL | 1 |
| Winicov, E | 1 |
| Dean, RH | 1 |
| Nicoletti, A | 1 |
| Heudes, D | 1 |
| Hinglais, N | 1 |
| Appay, MD | 1 |
| Philippe, M | 1 |
| Sassy-Prigent, C | 1 |
| Bariety, J | 1 |
| Michel, JB | 1 |
| Imamura, A | 1 |
| Mackenzie, HS | 1 |
| Lacy, ER | 1 |
| Hutchison, FN | 1 |
| Fitzgibbon, WR | 1 |
| Ploth, DW | 1 |
| Della Bruna, R | 1 |
| Bernhard, I | 1 |
| Gess, B | 1 |
| Schricker, K | 1 |
| Kurtz, A | 1 |
| Braam, B | 1 |
| Navar, LG | 1 |
| Mitchell, KD | 1 |
| Kabour, A | 1 |
| Henegar, JR | 1 |
| Devineni, VR | 1 |
| Janicki, JS | 1 |
| O'Sullivan, JB | 1 |
| Black, MJ | 1 |
| Bertram, JF | 1 |
| Bobik, A | 1 |
| Kost, CK | 1 |
| Pfeifer, CA | 1 |
| Jackson, EK | 1 |
| Ling, Q | 1 |
| Guo, ZG | 1 |
| Su, Z | 1 |
| Guo, X | 1 |
| Ponchon, P | 3 |
| Grichois, ML | 1 |
| Elghozi, JL | 3 |
| Sigmon, DH | 2 |
| Beierwaltes, WH | 3 |
| Wilcox, CS | 1 |
| Cardozo, J | 1 |
| Welch, WJ | 1 |
| Krasnikova, TL | 1 |
| Ashizawa, N | 1 |
| Graf, K | 1 |
| Do, YS | 1 |
| Nunohiro, T | 1 |
| Giachelli, CM | 1 |
| Meehan, WP | 1 |
| Tuan, TL | 1 |
| Hsueh, WA | 1 |
| Dussaillant, GR | 1 |
| Gonzalez, H | 1 |
| Cespedes, C | 1 |
| Jalil, JE | 1 |
| Barra, JG | 1 |
| Levenson, J | 1 |
| Armentano, RL | 1 |
| Cabrera Fischer, EI | 1 |
| Pichel, RH | 1 |
| Simon, A | 1 |
| Lee, BH | 1 |
| Shin, HS | 1 |
| Abdi, A | 1 |
| Johns, EJ | 1 |
| Wang, X | 1 |
| Aukland, K | 1 |
| Iversen, BM | 1 |
| Wolf, G | 1 |
| Schneider, A | 1 |
| Wenzel, U | 1 |
| Helmchen, U | 1 |
| Stahl, RA | 1 |
| Massart, PE | 1 |
| Hodeige, DG | 1 |
| Van Mechelen, H | 1 |
| Charlier, AA | 1 |
| Ketelslegers, JM | 1 |
| Heyndrickx, GR | 1 |
| Donckier, JE | 1 |
| Pipinos, II | 1 |
| Nypaver, TJ | 1 |
| Moshin, SK | 1 |
| Careterro, OA | 1 |
| Demeilliers, B | 1 |
| Jover, B | 1 |
| Mimran, A | 1 |
| Fuster, D | 1 |
| Paz Marco, M | 1 |
| Setoain, FJ | 1 |
| Oppenheimer, F | 1 |
| Lomeña, F | 1 |
| Siragy, HM | 1 |
| Carey, RM | 1 |
| Marsen, TA | 1 |
| Sukau, G | 1 |
| Pollok, M | 1 |
| Baldamus, CA | 1 |
| Rials, SJ | 1 |
| Xu, X | 1 |
| Wu, Y | 1 |
| Liu, T | 1 |
| Marinchack, RA | 1 |
| Kowey, PR | 1 |
| Maillard, JO | 1 |
| Descombes, E | 1 |
| Fellay, G | 1 |
| Regamey, C | 1 |
| Dobrian, AD | 1 |
| Schriver, SD | 1 |
| Prewitt, RL | 1 |
| Morgan, T | 1 |
| Aubert, JF | 1 |
| Brunner, H | 1 |
| Matys, T | 1 |
| Kucharewicz, I | 1 |
| Pawlak, D | 1 |
| Rólkowski, R | 1 |
| Wang, YX | 1 |
| Gavras, I | 1 |
| Wierzba, T | 1 |
| Gavras, H | 1 |
| De Nicola, L | 1 |
| Keiser, JA | 1 |
| Blantz, RC | 1 |
| Gabbai, FB | 1 |
1 review available for losartan and Goldblatt Syndrome
| Article | Year |
|---|---|
[Losartan, an angiotensin II receptor blocker: a new trend in cardiovascular chemotherapy].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compoun | 1996 |
72 other studies available for losartan and Goldblatt Syndrome
| Article | Year |
|---|---|
Losartan metabolite EXP3174 reduces the weight of formed thrombus in 2K1C hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Coagulation; Blood Platelets; Blood Pressure; Hemostasis; Hy | 2019 |
Fitness is improved by adjustments in muscle intracellular signaling in rats with renovascular hypertension 2K1C undergoing voluntary physical exercise.
Topics: Animals; Baroreflex; Blood Pressure; Bradycardia; Disease Models, Animal; Heart Rate; Hypertension, | 2020 |
Interaction between angiotensin II and GABA in the spinal cord regulates sympathetic vasomotor activity in Goldblatt hypertension.
Topics: Angiotensin II; Animals; Bicuculline; Blood Pressure; gamma-Aminobutyric Acid; Heart Rate; Hypertens | 2020 |
Intracranial Pressure During the Development of Renovascular Hypertension.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blood-Brain Barrier; Disease Models, Animal; Hyper | 2021 |
Effects of Captopril and Losartan on Cardiac Stereology in Rats with Renovascular Hypertension.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Dise | 2021 |
Effects of peripherally and centrally applied ghrelin on the oxidative stress induced by renin angiotensin system in a rat model of renovascular hypertension.
Topics: Angiotensin Receptor Antagonists; Animals; Arterial Pressure; Disease Models, Animal; Ghrelin; Heart | 2017 |
Direct renin inhibition is not enough to prevent reactive oxygen species generation and vascular dysfunction in renovascular hypertension.
Topics: Amides; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihyperte | 2018 |
Control of renal sympathetic nerve activity by neurotransmitters in the spinal cord in Goldblatt hypertension.
Topics: Animals; Baroreflex; Blood Pressure; Excitatory Amino Acid Agents; Heart Rate; Hypertension, Renovas | 2018 |
Losartan reduces oxidative stress within the rostral ventrolateral medulla of rats with renovascular hypertension.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Arterial Pressure; Baroreflex; Disease Models, Ani | 2013 |
[Effect of losartan on the protection of the kidney and PRCP-kallikrein axis of the two-kidney, one-clipped renovascular hypertensive rats].
Topics: Animals; Antihypertensive Agents; Blood Pressure; Carboxypeptidases; Hypertension, Renovascular; Kal | 2013 |
Reducing oxidative stress in the rostral ventrolateral medulla in renovascular hypertension by peripheral administration of losartan: how and where?
Topics: Animals; Hypertension, Renovascular; Losartan; Male; Oxidative Stress; Superoxide Dismutase; Ventral | 2013 |
Response to "Reducing oxidative stress in the rostral ventrolateral medulla in renovascular hypertension by peripheral administration of losartan: how and where?".
Topics: Animals; Hypertension, Renovascular; Losartan; Male; Oxidative Stress; Superoxide Dismutase; Ventral | 2013 |
Blockade of renin-angiotensin system prevents micturition dysfunction in renovascular hypertensive rats.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Animals; Antihypertensive Agents; Atenolol; Blood Press | 2014 |
Angiotensin-(1-7) enhances the effects of angiotensin II on the cardiac sympathetic afferent reflex and sympathetic activity in rostral ventrolateral medulla in renovascular hypertensive rats.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal | 2015 |
Exercise training attenuates renovascular hypertension partly via RAS- ROS- glutamate pathway in the hypothalamic paraventricular nucleus.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Disease Models, Animal; Dizocilpine Maleate; Excit | 2016 |
Involvement of prolylcarboxypeptidase in the effect of rutaecarpine on the regression of mesenteric artery hypertrophy in renovascular hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pre | 2009 |
Effects of allisartan, a new AT(1) receptor blocker, on blood pressure and end-organ damage in hypertensive animals.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Dogs; Female; Heart Rate; Humans; | 2009 |
Enhanced cardiac sympathetic afferent reflex involved in sympathetic overactivity in renovascular hypertensive rats.
Topics: Angiotensin II; Animals; Aortic Coarctation; Hypertension, Renovascular; Injections, Intravenous; In | 2009 |
Losartan exerts renoprotection through NAD(P)H oxidase downregulation in a renovascular model of hypertension.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Blotting, Western; Down-Regulation | 2009 |
Endogenous angiotensin II modulates nNOS expression in renovascular hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cyclic N-Oxides; Disease Models, A | 2009 |
[Effect of losartan on produce of sera autoantibodies to angiotensin II-1 receptor in renovascular hypertension rats].
Topics: Animals; Autoantibodies; Hypertension, Renovascular; Losartan; Male; Rats; Rats, Wistar; Receptors, | 2003 |
Effect of celecoxib on the antihypertensive effect of losartan in a rat model of renovascular hypertension.
Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Celecoxib; Cyclo | 2011 |
Endothelin-converting enzyme/neutral endopeptidase inhibitor SLV338 prevents hypertensive cardiac remodeling in a blood pressure-independent manner.
Topics: Analysis of Variance; Animals; Antihypertensive Agents; Aspartic Acid Endopeptidases; Blood Pressure | 2011 |
Hemin decreases cardiac oxidative stress and fibrosis in a rat model of systemic hypertension via PI3K/Akt signalling.
Topics: Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, New | 2011 |
The role of AT1 receptor-mediated reproductive function in renovascular hypertension in male rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Corticosterone; Hypertension, Reno | 2012 |
Upregulation of junctional adhesion molecule-A is a putative prognostic marker of hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Arterial | 2012 |
Angiotensin II and angiotensin-(1-7) in paraventricular nucleus modulate cardiac sympathetic afferent reflex in renovascular hypertensive rats.
Topics: Afferent Pathways; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Body Weight; Heart; Heart | 2012 |
Involvement of calcitonin gene-related peptide in the depressor effects of losartan and perindopril in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Calciton | 2003 |
Effect of losartan on insulin plasma concentrations and LPL activity in adipose tissue of hypertensive rats.
Topics: Adipose Tissue; Adrenal Glands; Angiotensin II; Animals; Antihypertensive Agents; Constriction; Hype | 2003 |
Two episodes of anuria and acute pulmonary edema in a losartan-treated patient with solitary kidney.
Topics: Adult; Antihypertensive Agents; Anuria; Female; Humans; Hypertension, Renovascular; Losartan; Pulmon | 2004 |
Effect of losartan and enalapril on cognitive deficit caused by Goldblatt induced hypertension.
Topics: Acetylcholinesterase; Animals; Antihypertensive Agents; Blood Pressure; Brain; Cognition; Enalapril; | 2005 |
Angiotensin II enhances thrombosis development in renovascular hypertensive rats.
Topics: alpha-2-Antiplasmin; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin III; Anima | 2005 |
Losartan reduces monocyte chemoattractant protein-1 expression in aortic tissues of 2K1C hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta; Bl | 2006 |
Angiotensin II via AT1 receptor accelerates arterial thrombosis in renovascular hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Carotid Artery Thrombosis; Carotid | 2005 |
Dilation of renal artery stenosis after administration of losartan.
Topics: Adult; Angioplasty, Balloon; Antihypertensive Agents; Female; Fibromuscular Dysplasia; Humans; Hyper | 2007 |
Calcitonin gene-related Peptide-mediated depressor effect and inhibiting vascular hypertrophy of rutaecarpine in renovascular hypertensive rats.
Topics: Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Vessels; Calcitonin Ge | 2007 |
Angiotensin II regulates cardiac hypertrophy via oxidative stress but not antioxidant enzyme activities in experimental renovascular hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Catalase; Glutathione; Hypertension, Renovasc | 2008 |
Angiotensin-(1-7) and nitric oxide interaction in renovascular hypertension.
Topics: Amino Acid Oxidoreductases; Angiotensin I; Angiotensin II; Angiotensins; Animals; Arginine; Biphenyl | 1995 |
Left ventricular fibrosis in renovascular hypertensive rats. Effect of losartan and spironolactone.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biochemical Phen | 1995 |
Effects of chronic treatment with angiotensin converting enzyme inhibitor or an angiotensin receptor antagonist in two-kidney, one-clip hypertensive rats.
Topics: Albuminuria; Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphen | 1995 |
Renin gene and angiotensin II AT1 receptor gene expression in the kidneys of normal and of two-kidney/one-clip rats.
Topics: Angiotensin Receptor Antagonists; Animals; Base Sequence; Biphenyl Compounds; Gene Expression; Hyper | 1995 |
Modulation of tubuloglomerular feedback by angiotensin II type 1 receptors during the development of Goldblatt hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Pressur | 1995 |
Prevention of angiotensin II induced myocyte necrosis and coronary vascular damage by lisinopril and losartan in the rat.
Topics: Angiotensin I; Angiotensin II; Animals; Biphenyl Compounds; Coronary Vessels; Dose-Response Relation | 1995 |
Cardiovascular hypertrophy in one-kidney, one clip renal hypertensive rats: a role for angiotensin II?
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; | 1994 |
Telemetric blood pressure monitoring in benign 2-kidney, 1-clip renovascular hypertension: effect of chronic caffeine ingestion.
Topics: Angiotensin II; Animals; Biphenyl Compounds; Blood Pressure; Caffeine; Captopril; Constriction; Hear | 1994 |
Regression of cardiac hypertrophy and myosin isoenzyme patterns by losartan and captopril in renovascular hypertensive rats.
Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Captopril; H | 1994 |
Effect of losartan on short-term variability of blood pressure of renovascular hypertensive rats: a spectral study.
Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressu | 1993 |
Renal nitric oxide and angiotensin II interaction in renovascular hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Arginine; Biphenyl Compounds; Endothelium, Vascula | 1993 |
[Hormonal contribution to short-term variability of blood pressure in a renovascular hypertension model].
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihyperten | 1995 |
Contribution of the renin-angiotensin and kallikrein-kinin systems to short-term variability of blood pressure in two-kidney, one-clip hypertensive rats.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihyperten | 1996 |
AT1 and TxA2/PGH2 receptors maintain hypertension throughout 2K,1C Goldblatt hypertension in the rat.
Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressu | 1996 |
Osteopontin is produced by rat cardiac fibroblasts and mediates A(II)-induced DNA synthesis and collagen gel contraction.
Topics: Angiotensin II; Animals; Antibodies, Blocking; Antibodies, Monoclonal; Biphenyl Compounds; Blotting, | 1996 |
Regression of left ventricular hypertrophy in experimental renovascular hypertension: diastolic dysfunction depends more on myocardial collagen than it does on myocardial mass.
Topics: Animals; Biphenyl Compounds; Blood Pressure; Collagen; Diastole; Enalapril; Hypertension, Renovascul | 1996 |
In vivo angiotensin II receptor blockade and converting enzyme inhibition on canine aortic viscoelasticity.
Topics: Angiotensin I; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; | 1997 |
Interaction of nitric oxide and the renin angiotensin system in renal hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Enzyme Inhibit | 1997 |
The effect of angiotensin II receptor antagonists on kidney function in two-kidney, two-clip Goldblatt hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; | 1997 |
Acute effects of angiotensin II receptor antagonist on autoregulation of zonal glomerular filtration rate in renovascular hypertensive rats.
Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Glomerular Filtr | 1997 |
Influence of nitric oxide in the chronic phase of two-kidney, one clip renovascular hypertension.
Topics: Animals; Antihypertensive Agents; Chronic Disease; Enzyme Inhibitors; Hemodynamics; Hypertension, Re | 1998 |
Regulation of glomerular TGF-beta expression in the contralateral kidney of two-kidney, one-clip hypertensive rats.
Topics: Animals; Antihypertensive Agents; Drug Combinations; Hydralazine; Hydrochlorothiazide; Hypertension, | 1998 |
Angiotensin II and endothelin-1 receptor antagonists have cumulative hypotensive effects in canine Page hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Bosentan; Disease Models, | 1998 |
Response to angiotensin inhibition in rats with sustained renovascular hypertension correlates with response to removing renal artery stenosis.
Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Disease Models, Animal; Hyperten | 1998 |
Contrasting renal effects of chronic administrations of enalapril and losartan on one-kidney, one clip hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pr | 1998 |
A case of renal artery stenosis after transplantation: can losartan be more accurate than captopril renography?
Topics: Adult; Antihypertensive Agents; Captopril; Humans; Hypertension, Renovascular; Kidney Transplantatio | 1998 |
Protective role of the angiotensin AT2 receptor in a renal wrap hypertension model.
Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Ag | 1999 |
Enalapril and losartan augment endogenous nitric oxide release in Takayasu's arteritis--a case report.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Enalapril; Endothelin-1; Female; | 2000 |
Restoration of normal ventricular electrophysiology in renovascular hypertensive rabbits after treatment with losartan.
Topics: Action Potentials; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Hyper | 2001 |
Repeated transient anuria following losartan administration in a patient with a solitary kidney.
Topics: Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Anuria; Humans; Hypertension, Renov | 2001 |
Role of angiotensin II and free radicals in blood pressure regulation in a rat model of renal hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Blood Pressure; Blotting | 2001 |
Interaction between sodium intake, angiotensin II, and blood pressure as a cause of cardiac hypertrophy.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Cardiomegaly; Circadian | 2001 |
The involvement of AT(2)-receptor in the antithrombotic effect of losartan in renal hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Fibrinolytic Agents; Hypertension, Renovascular; I | 2000 |
Comparison of systemic and regional hemodynamic effects of a diuretic, an angiotensin II receptor antagonist, and an angiotensin-converting enzyme inhibitor in conscious renovascular hypertensive rats.
Topics: Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Consciousness; Enalapril; Furo | 1992 |
Angiotensin II and renal functional reserve in rats with Goldblatt hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Captopril; Glycine; Hemodynami | 1992 |