losartan has been researched along with Glucose Intolerance in 6 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
Glucose Intolerance: A pathological state in which BLOOD GLUCOSE level is less than approximately 140 mg/100 ml of PLASMA at fasting, and above approximately 200 mg/100 ml plasma at 30-, 60-, or 90-minute during a GLUCOSE TOLERANCE TEST. This condition is seen frequently in DIABETES MELLITUS, but also occurs with other diseases and MALNUTRITION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of this study was to observe the antihypertensive effect of losartan and levamlodipine besylate on insulin resistance in patients with essential hypertension (EH) combined with isolated impaired fasting glucose (i-IFG)." | 9.22 | Effects of antihypertensive drugs losartan and levamlodipine besylate on insulin resistance in patients with essential hypertension combined with isolated impaired fasting glucose. ( Jiang, XS; Liu, L; Ning, N; Tan, MH; Wei, P; Xiao, WY; Yi, D; Zhou, L, 2016) |
| " Since treatment with angiotensin II receptor blockers retards the development of diabetes, the effects of losartan on serum adiponectin levels were examined with regard to insulin sensitivity in pre-diabetic patients." | 9.13 | Losartan elevates the serum high-molecular weight-adiponectin isoform and concurrently improves insulin sensitivity in patients with impaired glucose metabolism. ( Higuchi, C; Naito, T; Nishimura, H; Otsuka, K; Sanaka, T; Tanihata, Y, 2008) |
| "The objective of this study was to observe the antihypertensive effect of losartan and levamlodipine besylate on insulin resistance in patients with essential hypertension (EH) combined with isolated impaired fasting glucose (i-IFG)." | 5.22 | Effects of antihypertensive drugs losartan and levamlodipine besylate on insulin resistance in patients with essential hypertension combined with isolated impaired fasting glucose. ( Jiang, XS; Liu, L; Ning, N; Tan, MH; Wei, P; Xiao, WY; Yi, D; Zhou, L, 2016) |
| " Since treatment with angiotensin II receptor blockers retards the development of diabetes, the effects of losartan on serum adiponectin levels were examined with regard to insulin sensitivity in pre-diabetic patients." | 5.13 | Losartan elevates the serum high-molecular weight-adiponectin isoform and concurrently improves insulin sensitivity in patients with impaired glucose metabolism. ( Higuchi, C; Naito, T; Nishimura, H; Otsuka, K; Sanaka, T; Tanihata, Y, 2008) |
| "Oral losartan treatment delayed the onset of diabetes, and reduced hyperglycemia and glucose intolerance in db/db mice, but did not affect the insulin sensitivity of peripheral tissues." | 1.33 | Angiotensin II type 1 receptor blockade improves beta-cell function and glucose tolerance in a mouse model of type 2 diabetes. ( Carlsson, PO; Chu, KY; Lau, T; Leung, PS, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xiao, WY | 1 |
| Ning, N | 1 |
| Tan, MH | 1 |
| Jiang, XS | 1 |
| Zhou, L | 1 |
| Liu, L | 1 |
| Yi, D | 1 |
| Wei, P | 1 |
| Nishimura, H | 1 |
| Sanaka, T | 1 |
| Tanihata, Y | 1 |
| Naito, T | 1 |
| Higuchi, C | 1 |
| Otsuka, K | 1 |
| Wong, YC | 1 |
| Sim, MK | 1 |
| Lee, KO | 1 |
| Yoshida, D | 1 |
| Higashiura, K | 1 |
| Shimamoto, K | 1 |
| Chu, KY | 1 |
| Lau, T | 1 |
| Carlsson, PO | 1 |
| Leung, PS | 1 |
| Zandbergen, AA | 1 |
| Lamberts, SW | 1 |
| Janssen, JA | 1 |
| Bootsma, AH | 1 |
1 review available for losartan and Glucose Intolerance
| Article | Year |
|---|---|
[Treatment of hypertensive patients with impaired glucose tolerance (IGT)].
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive | 2005 |
3 trials available for losartan and Glucose Intolerance
| Article | Year |
|---|---|
Effects of antihypertensive drugs losartan and levamlodipine besylate on insulin resistance in patients with essential hypertension combined with isolated impaired fasting glucose.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Essential Hypertension; F | 2016 |
Losartan elevates the serum high-molecular weight-adiponectin isoform and concurrently improves insulin sensitivity in patients with impaired glucose metabolism.
Topics: Adiponectin; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Fe | 2008 |
Short-term administration of an angiotensin-receptor antagonist in patients with impaired fasting glucose improves insulin sensitivity and increases free IGF-I.
Topics: Angiotensin II Type 1 Receptor Blockers; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; F | 2006 |
2 other studies available for losartan and Glucose Intolerance
| Article | Year |
|---|---|
Des-aspartate-angiotensin-I and angiotensin IV improve glucose tolerance and insulin signalling in diet-induced hyperglycaemic mice.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Glucose; Cystinyl Aminopeptidase; Dietary Fats; Dietar | 2011 |
Angiotensin II type 1 receptor blockade improves beta-cell function and glucose tolerance in a mouse model of type 2 diabetes.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Disease | 2006 |