losartan has been researched along with Glial Cell Tumors in 5 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
| Excerpt | Relevance | Reference |
|---|---|---|
| "Malignant gliomas have a highly immune suppressive tumor microenvironment (TME) which renders them largely unresponsive to conventional therapeutics." | 5.72 | Reprogramming the Canine Glioma Microenvironment with Tumor Vaccination plus Oral Losartan and Propranolol Induces Objective Responses. ( Ammons, DT; Boss, MK; Chow, L; Dow, S; Frank, C; Griffin, JF; Guth, A; Kurihara, J; MacQuiddy, B; Makii, R; Marolf, AJ; McGrath, S; Packer, RA; Regan, DP; Rozental, AJ, 2022) |
| "Malignant gliomas have a highly immune suppressive tumor microenvironment (TME) which renders them largely unresponsive to conventional therapeutics." | 1.72 | Reprogramming the Canine Glioma Microenvironment with Tumor Vaccination plus Oral Losartan and Propranolol Induces Objective Responses. ( Ammons, DT; Boss, MK; Chow, L; Dow, S; Frank, C; Griffin, JF; Guth, A; Kurihara, J; MacQuiddy, B; Makii, R; Marolf, AJ; McGrath, S; Packer, RA; Regan, DP; Rozental, AJ, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ammons, DT | 1 |
| Guth, A | 1 |
| Rozental, AJ | 1 |
| Kurihara, J | 1 |
| Marolf, AJ | 1 |
| Chow, L | 1 |
| Griffin, JF | 1 |
| Makii, R | 1 |
| MacQuiddy, B | 1 |
| Boss, MK | 1 |
| Regan, DP | 1 |
| Frank, C | 1 |
| McGrath, S | 1 |
| Packer, RA | 1 |
| Dow, S | 1 |
| Moeller, I | 1 |
| Albiston, AL | 1 |
| Lew, RA | 1 |
| Mendelsohn, FA | 1 |
| Chai, SY | 1 |
| Rivera, E | 1 |
| Arrieta, O | 1 |
| Guevara, P | 1 |
| Duarte-Rojo, A | 1 |
| Sotelo, J | 1 |
| Leung, KH | 1 |
| Chang, RS | 1 |
| Lotti, VJ | 1 |
| Roscoe, WA | 1 |
| Smith, RD | 1 |
| Timmermans, PB | 1 |
| Chiu, AT | 1 |
| Jaiswal, N | 1 |
| Diz, DI | 1 |
| Tallant, EA | 1 |
| Khosla, MC | 1 |
| Ferrario, CM | 1 |
5 other studies available for losartan and Glial Cell Tumors
| Article | Year |
|---|---|
Reprogramming the Canine Glioma Microenvironment with Tumor Vaccination plus Oral Losartan and Propranolol Induces Objective Responses.
Topics: Animals; Brain Neoplasms; Cancer Vaccines; Dogs; Glioma; Losartan; Propranolol; Prospective Studies; | 2022 |
A globin fragment, LVV-hemorphin-7, induces [3H]thymidine incorporation in a neuronal cell line via the AT4 receptor.
Topics: Angiotensin II; Binding, Competitive; DNA; Glioma; Hemoglobins; Hybrid Cells; Losartan; Neuroblastom | 1999 |
AT1 receptor is present in glioma cells; its blockage reduces the growth of rat glioma.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Brain Neoplasms; Cell Division; Glioma; Losartan; | 2001 |
AT1 receptors mediate the release of prostaglandins in porcine smooth muscle cells and rat astrocytes.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arachidonic Acids; Astrocytes; Biphenyl C | 1992 |
Characterization of angiotensin receptors mediating prostaglandin synthesis in C6 glioma cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Glioma; Imidazoles; Losart | 1991 |