losartan and Glaucoma
losartan has been researched along with Glaucoma in 2 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "The neuroprotective effect of losartan in mouse glaucoma is associated with adaptive changes in the sclera expressed at the optic nerve head." | 7.81 | Losartan Treatment Protects Retinal Ganglion Cells and Alters Scleral Remodeling in Experimental Glaucoma. ( Berlinicke, CA; Jefferys, JJ; Kim, J; Kimball, EC; Mitchell, KL; Nguyen, C; Nguyen, TD; Oglesby, EN; Pease, ME; Pitha, IF; Quigley, HA; Steinhart, MR; Welsbie, DS, 2015) |
| "The neuroprotective effect of losartan in mouse glaucoma is associated with adaptive changes in the sclera expressed at the optic nerve head." | 3.81 | Losartan Treatment Protects Retinal Ganglion Cells and Alters Scleral Remodeling in Experimental Glaucoma. ( Berlinicke, CA; Jefferys, JJ; Kim, J; Kimball, EC; Mitchell, KL; Nguyen, C; Nguyen, TD; Oglesby, EN; Pease, ME; Pitha, IF; Quigley, HA; Steinhart, MR; Welsbie, DS, 2015) |
| "To examine the effects of losartan on scar formation after trabeculectomy and on fibrotic changes of human Tenon's fibroblasts (HTFs)." | 1.46 | Losartan Attenuates Scar Formation in Filtering Bleb After Trabeculectomy. ( Fu, S; Shi, H; Wang, H; Xiao, Y; Xu, K; Ye, W; Zhang, X, 2017) |
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Quigley, HA | 1 |
| Pitha, IF | 1 |
| Welsbie, DS | 1 |
| Nguyen, C | 1 |
| Steinhart, MR | 1 |
| Nguyen, TD | 1 |
| Pease, ME | 1 |
| Oglesby, EN | 1 |
| Berlinicke, CA | 1 |
| Mitchell, KL | 1 |
| Kim, J | 1 |
| Jefferys, JJ | 1 |
| Kimball, EC | 1 |
| Shi, H | 1 |
| Wang, H | 1 |
| Fu, S | 1 |
| Xu, K | 1 |
| Zhang, X | 1 |
| Xiao, Y | 1 |
| Ye, W | 1 |
Other Studies
2 other studies available for losartan and Glaucoma
| Article | Year |
|---|---|
Losartan Treatment Protects Retinal Ganglion Cells and Alters Scleral Remodeling in Experimental Glaucoma.
Topics: Animals; Disease Models, Animal; Glaucoma; Humans; Intraocular Pressure; Losartan; Mice; Neuroprotec | 2015 |
Losartan Attenuates Scar Formation in Filtering Bleb After Trabeculectomy.
Topics: Actins; Aged; Angiotensin II Type 1 Receptor Blockers; Animals; Blotting, Western; Cell Movement; Ce | 2017 |