Page last updated: 2024-10-30

losartan and Glaucoma

losartan has been researched along with Glaucoma in 2 studies

Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position

Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)

Research Excerpts

ExcerptRelevanceReference
"The neuroprotective effect of losartan in mouse glaucoma is associated with adaptive changes in the sclera expressed at the optic nerve head."7.81Losartan Treatment Protects Retinal Ganglion Cells and Alters Scleral Remodeling in Experimental Glaucoma. ( Berlinicke, CA; Jefferys, JJ; Kim, J; Kimball, EC; Mitchell, KL; Nguyen, C; Nguyen, TD; Oglesby, EN; Pease, ME; Pitha, IF; Quigley, HA; Steinhart, MR; Welsbie, DS, 2015)
"The neuroprotective effect of losartan in mouse glaucoma is associated with adaptive changes in the sclera expressed at the optic nerve head."3.81Losartan Treatment Protects Retinal Ganglion Cells and Alters Scleral Remodeling in Experimental Glaucoma. ( Berlinicke, CA; Jefferys, JJ; Kim, J; Kimball, EC; Mitchell, KL; Nguyen, C; Nguyen, TD; Oglesby, EN; Pease, ME; Pitha, IF; Quigley, HA; Steinhart, MR; Welsbie, DS, 2015)
"To examine the effects of losartan on scar formation after trabeculectomy and on fibrotic changes of human Tenon's fibroblasts (HTFs)."1.46Losartan Attenuates Scar Formation in Filtering Bleb After Trabeculectomy. ( Fu, S; Shi, H; Wang, H; Xiao, Y; Xu, K; Ye, W; Zhang, X, 2017)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Quigley, HA1
Pitha, IF1
Welsbie, DS1
Nguyen, C1
Steinhart, MR1
Nguyen, TD1
Pease, ME1
Oglesby, EN1
Berlinicke, CA1
Mitchell, KL1
Kim, J1
Jefferys, JJ1
Kimball, EC1
Shi, H1
Wang, H1
Fu, S1
Xu, K1
Zhang, X1
Xiao, Y1
Ye, W1

Other Studies

2 other studies available for losartan and Glaucoma

ArticleYear
Losartan Treatment Protects Retinal Ganglion Cells and Alters Scleral Remodeling in Experimental Glaucoma.
    PloS one, 2015, Volume: 10, Issue:10

    Topics: Animals; Disease Models, Animal; Glaucoma; Humans; Intraocular Pressure; Losartan; Mice; Neuroprotec

2015
Losartan Attenuates Scar Formation in Filtering Bleb After Trabeculectomy.
    Investigative ophthalmology & visual science, 2017, 03-01, Volume: 58, Issue:3

    Topics: Actins; Aged; Angiotensin II Type 1 Receptor Blockers; Animals; Blotting, Western; Cell Movement; Ce

2017