losartan has been researched along with Encephalopathy, Traumatic in 3 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
| Excerpt | Relevance | Reference |
|---|---|---|
| " Furthermore, most preclinical antiepileptogenic studies lack information needed for translation, such as dose-blood level relationship, brain target engagement, and dose-response, and many use treatment parameters that cannot be applied clinically, for example, treatment initiation before or at the time of injury and dosing higher than tolerated human equivalent dosing." | 2.66 | Repurposed molecules for antiepileptogenesis: Missing an opportunity to prevent epilepsy? ( Bar-Klein, G; Friedman, A; Hameed, MQ; Jozwiak, S; Kaminski, RM; Klein, P; Klitgaard, H; Koepp, M; Löscher, W; Prince, DA; Rotenberg, A; Twyman, R; Vezzani, A; Wong, M, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Welling, LC | 1 |
| Rabelo, NN | 1 |
| Gonçalves de Sena Barbosa, M | 1 |
| Luciano, LL | 1 |
| Figueiredo, EG | 1 |
| Klein, P | 1 |
| Friedman, A | 2 |
| Hameed, MQ | 1 |
| Kaminski, RM | 1 |
| Bar-Klein, G | 1 |
| Klitgaard, H | 1 |
| Koepp, M | 1 |
| Jozwiak, S | 1 |
| Prince, DA | 2 |
| Rotenberg, A | 1 |
| Twyman, R | 1 |
| Vezzani, A | 1 |
| Wong, M | 1 |
| Löscher, W | 1 |
| Kim, SY | 1 |
| Senatorov, VV | 1 |
| Morrissey, CS | 1 |
| Lippmann, K | 1 |
| Vazquez, O | 1 |
| Milikovsky, DZ | 1 |
| Gu, F | 1 |
| Parada, I | 1 |
| Becker, AJ | 1 |
| Heinemann, U | 1 |
| Kaufer, D | 1 |
1 review available for losartan and Encephalopathy, Traumatic
| Article | Year |
|---|---|
Repurposed molecules for antiepileptogenesis: Missing an opportunity to prevent epilepsy?
Topics: Acetylcysteine; Animals; Anticonvulsants; Antioxidants; Atorvastatin; Brain Injuries, Traumatic; Cef | 2020 |
2 other studies available for losartan and Encephalopathy, Traumatic
| Article | Year |
|---|---|
Losartan and Traumatic Brain Injury: Why Is a Retrospective Study Urgent?
Topics: Angiotensin II Type 1 Receptor Blockers; Blood-Brain Barrier; Brain Injuries, Traumatic; Humans; Los | 2021 |
TGFβ signaling is associated with changes in inflammatory gene expression and perineuronal net degradation around inhibitory neurons following various neurological insults.
Topics: Astrocytes; Blood-Brain Barrier; Brain Injuries, Traumatic; Cerebral Cortex; Computational Biology; | 2017 |